SUPERFAMILY 1.75 HMM library and genome assignments server

C-terminal domain of PLC-beta superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Antiparallel coiled-coil [ 58086] (17)
Superfamily:   C-terminal domain of PLC-beta [ 69989]
Families:   C-terminal domain of PLC-beta [ 69990]


Superfamily statistics
Genomes (180) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 575 639 1
Proteins 564 636 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) multicellular organismal process 0.00001886 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.0002447 Least Informative Direct
Biological Process (BP) response to stimulus 0.01843 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.5642 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.5738 Least Informative Inherited
Biological Process (BP) system process 0.0000006878 Moderately Informative Direct
Biological Process (BP) lipid metabolic process 0.000002126 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.000002312 Moderately Informative Direct
Biological Process (BP) signal transduction 0.0004181 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.000000007228 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.000164 Moderately Informative Direct
Biological Process (BP) phospholipid metabolic process 0.0000004345 Informative Direct
Biological Process (BP) single-organism behavior 0.000002994 Informative Direct
Biological Process (BP) sensory perception 0.07463 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0.000005868 Least Informative Direct
Molecular Function (MF) binding 0.004862 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.0000000002608 Moderately Informative Direct
Molecular Function (MF) phosphoric ester hydrolase activity 0.0000000000005253 Informative Direct
Molecular Function (MF) phosphoric diester hydrolase activity 0 Highly Informative Direct
Molecular Function (MF) lipase activity 0 Highly Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.0004014 Least Informative Direct
Cellular Component (CC) cell projection 0.01069 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoinositide phospholipase C0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0InformativeDirect
Enzyme Commission (EC)Phosphoinositide phospholipase C0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processLipid metabolism0Moderately InformativeDirect
Biological processLipid degradation0Highly InformativeDirect
Coding sequence diversityAlternative splicing0.0000000000001633Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Post-translational modificationHydrolase0.000000000000009814Least InformativeDirect
Post-translational modificationTransducer0InformativeDirect
Post-translational modificationPhosphoprotein0.000000009923Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-terminal domain of PLC-beta domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the C-terminal domain of PLC-beta superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]