SUPERFAMILY 1.75 HMM library and genome assignments server

N-terminal coiled coil domain from apc superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   N-terminal coiled coil domain from apc [ 58050]
Families:   N-terminal coiled coil domain from apc [ 58051]


Superfamily statistics
Genomes (86) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 169 178 1
Proteins 169 178 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 0.00000001664 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.0000000326 Least Informative Direct
Biological Process (BP) localization 0.0000002886 Least Informative Direct
Biological Process (BP) response to stimulus 0.000004382 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00001074 Least Informative Direct
Biological Process (BP) developmental process 0.00008167 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.0002066 Least Informative Direct
Biological Process (BP) regulation of metabolic process 0.002087 Least Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.0000000000001194 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 0.000000000002933 Moderately Informative Direct
Biological Process (BP) nervous system development 0.000000000454 Moderately Informative Direct
Biological Process (BP) organ development 0.00000003073 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.00000003092 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0000001425 Moderately Informative Direct
Biological Process (BP) immune system process 0.0000003124 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.000001466 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.000001629 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.000003794 Moderately Informative Direct
Biological Process (BP) tissue development 0.0001378 Moderately Informative Direct
Biological Process (BP) signal transduction 0.0005768 Moderately Informative Direct
Biological Process (BP) organelle organization 0.001679 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.003743 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.03825 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.005665 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.001692 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.009381 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.002775 Moderately Informative Inherited
Biological Process (BP) localization of cell 0 Informative Direct
Biological Process (BP) regulation of protein localization 0 Informative Direct
Biological Process (BP) locomotion 0.0000000000002929 Informative Direct
Biological Process (BP) leukocyte activation 0.0000000000005212 Informative Direct
Biological Process (BP) generation of neurons 0.000000000009399 Informative Direct
Biological Process (BP) cell cycle process 0.00000000001713 Informative Direct
Biological Process (BP) regulation of organelle organization 0.00000000005861 Informative Direct
Biological Process (BP) cellular component movement 0.0000000002053 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.0000000003133 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.0000000003392 Informative Direct
Biological Process (BP) chromosome organization 0.0000000003991 Informative Direct
Biological Process (BP) cytoskeleton organization 0.000000001058 Informative Direct
Biological Process (BP) cell projection organization 0.000000001862 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.000000002434 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.000000004252 Informative Direct
Biological Process (BP) regulation of locomotion 0.000000004579 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.000000006562 Informative Direct
Biological Process (BP) microtubule-based process 0.00000002035 Informative Direct
Biological Process (BP) sensory organ development 0.0000000483 Informative Direct
Biological Process (BP) negative regulation of signaling 0.0000000801 Informative Direct
Biological Process (BP) negative regulation of cell communication 0.0000002072 Informative Direct
Biological Process (BP) positive regulation of cellular component organization 0.0000003212 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.0000003754 Informative Direct
Biological Process (BP) hematopoietic or lymphoid organ development 0.0000004077 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.0000009825 Informative Direct
Biological Process (BP) cellular component morphogenesis 0.000009178 Informative Direct
Biological Process (BP) negative regulation of developmental process 0.0001637 Informative Direct
Biological Process (BP) positive regulation of protein metabolic process 0.00024 Informative Direct
Biological Process (BP) negative regulation of cell death 0.0003527 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 0.01237 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.0282 Informative Inherited
Biological Process (BP) hair follicle development 0 Highly Informative Direct
Biological Process (BP) regulation of epithelial cell differentiation 0 Highly Informative Direct
Biological Process (BP) regulation of myeloid cell differentiation 0 Highly Informative Direct
Biological Process (BP) regulation of microtubule polymerization or depolymerization 0 Highly Informative Direct
Biological Process (BP) positive regulation of programmed cell death 0 Highly Informative Direct
Biological Process (BP) positive regulation of cell migration 0 Highly Informative Direct
Biological Process (BP) regulation of leukocyte differentiation 0 Highly Informative Direct
Biological Process (BP) T cell differentiation 0 Highly Informative Direct
Biological Process (BP) positive regulation of catabolic process 0 Highly Informative Direct
Biological Process (BP) negative regulation of cytoskeleton organization 0 Highly Informative Direct
Biological Process (BP) regulation of protein complex disassembly 0 Highly Informative Direct
Biological Process (BP) regulation of organ morphogenesis 0.000000000000001938 Highly Informative Direct
Biological Process (BP) neuron projection development 0.0000000000000161 Highly Informative Direct
Biological Process (BP) retina development in camera-type eye 0.00000000000005424 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 0.000000000002667 Highly Informative Direct
Biological Process (BP) regulation of cell division 0.000000000002675 Highly Informative Direct
Biological Process (BP) cell division 0.000000000005609 Highly Informative Direct
Biological Process (BP) regulation of reproductive process 0.000000001041 Highly Informative Direct
Biological Process (BP) pattern specification process 0.000000003069 Highly Informative Direct
Biological Process (BP) regulation of cell adhesion 0.000000004021 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.000000005861 Highly Informative Direct
Biological Process (BP) regulation of protein catabolic process 0.00000000829 Highly Informative Direct
Biological Process (BP) renal system development 0.00000001389 Highly Informative Direct
Biological Process (BP) positive regulation of organelle organization 0.00000006301 Highly Informative Direct
Biological Process (BP) stem cell development 0.000001493 Highly Informative Direct
Biological Process (BP) regulation of protein complex assembly 0.000008965 Highly Informative Direct
Biological Process (BP) negative regulation of cell differentiation 0.00007678 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.00009998 Highly Informative Direct
Biological Process (BP) mitosis 0.0001576 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.0004055 Highly Informative Direct
Biological Process (BP) negative regulation of apoptotic process 0.007895 Highly Informative Inherited
Molecular Function (MF) binding 0.00006067 Least Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.000000000001214 Informative Direct
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.000000000009637 Least Informative Direct
Cellular Component (CC) protein complex 0.0000000000243 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000000002509 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000001408 Least Informative Direct
Cellular Component (CC) membrane 0.000001468 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.000002406 Least Informative Direct
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.000000000006339 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.0000002061 Moderately Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0 Informative Direct
Cellular Component (CC) neuron projection 0.02261 Informative Inherited
Cellular Component (CC) cell projection membrane 0 Highly Informative Direct
Cellular Component (CC) growth cone 0.000000004677 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processWnt signaling pathway0InformativeDirect
Cellular componentMembrane0.00002937Least InformativeDirect
Cellular componentCytoplasm0.002349Least InformativeInherited
Cellular componentCytoskeleton0.00000000001027Moderately InformativeDirect
Cellular componentCell membrane0.0000005356Moderately InformativeDirect
Cellular componentMicrotubule0.00000000000001006InformativeDirect
DomainRepeat0Least InformativeDirect
DomainCoiled coil0Moderately InformativeDirect

Document: KW annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a N-terminal coiled coil domain from apc domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the N-terminal coiled coil domain from apc superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]