SUPERFAMILY 1.75 HMM library and genome assignments server

Trimerization domain of TRAF superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Trimerization domain of TRAF [ 57953]
Families:   Trimerization domain of TRAF [ 57954] (2)


Superfamily statistics
Genomes (69) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 220 220 6
Proteins 220 220 6


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 0.0001232 Least Informative Direct
Biological Process (BP) response to stimulus 0.000004591 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.001103 Least Informative Inherited
Biological Process (BP) signal transduction 0.000000008832 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.0001336 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 0.2242 Moderately Informative Inherited
Biological Process (BP) regulation of immune effector process 0.000066 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 0.005113 Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.000003075 Highly Informative Direct
Cellular Component (CC) membrane 0.00004079 Least Informative Direct

Document: GO annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Trimerization domain of TRAF domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Trimerization domain of TRAF superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Internal database links ]