Ada DNA repair protein, N-terminal domain (N-Ada 10) superfamily
|General category ||Information|
|Detailed category ||DNA replication/repair|
Document: Function annotation of SCOP domain superfamilies
Enzyme Commission (EC)(show details)
Highlighted in gray are those with FDR_all>0.001
Document: EC annotation of SCOP domains
|Cross references ||IPR004026 SSF57884 Protein matches|
|Abstract ||The Escherichia coli Ada protein repairs O6-methylguanine residues and methyl phosphotriesters in DNA by direct transfer of the methyl group to a
cysteine residue. This domain contains four conserved cysteines that form a
zinc binding site [1581309, 8500619]. One of these cysteines is a methyl group acceptor. The methylated domain can then specifically bind to the ada box on a DNA duplex .|
PDBeMotif information about ligands, sequence and structure motifs
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Internal database links
Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
Alignments of sequences to 1 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
Browse and view proteins in genomes which have
different domain combinations including a Ada DNA repair protein, N-terminal domain (N-Ada 10) domain.
Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
There are 1 hidden Markov models representing the Ada DNA repair protein, N-terminal domain (N-Ada 10) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Internal database links ]