SUPERFAMILY 1.75 HMM library and genome assignments server

Probable ACP-binding domain of malonyl-CoA ACP transacylase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   Probable ACP-binding domain of malonyl-CoA ACP transacylase [ 55048]
Families:   Probable ACP-binding domain of malonyl-CoA ACP transacylase [ 55049]


Superfamily statistics
Genomes (2,782) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 8,622 32,921 2
Proteins 7,918 30,942 2


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.3679 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.47 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.8676 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.01538 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.00000002881 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 0.0000001514 Moderately Informative Direct
Biological Process (BP) monocarboxylic acid metabolic process 0.0000004009 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.03289 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.1897 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.0271 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.8855 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.008647 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.931 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.001166 Moderately Informative Inherited
Biological Process (BP) secondary metabolic process 0 Informative Direct
Biological Process (BP) cellular ketone metabolic process 0.00000000000003788 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.0000000000002433 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.00000000001909 Informative Direct
Biological Process (BP) amide biosynthetic process 0.00000002433 Informative Direct
Biological Process (BP) fatty acid metabolic process 0.00000004443 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.0000002945 Informative Direct
Biological Process (BP) peptide metabolic process 0.00003926 Informative Direct
Biological Process (BP) alcohol metabolic process 0.2521 Informative Inherited
Biological Process (BP) phenol-containing compound metabolic process 0 Highly Informative Direct
Biological Process (BP) peptide biosynthetic process 0.00000002129 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 0.00001762 Highly Informative Direct
Biological Process (BP) polyol metabolic process 0.00002513 Highly Informative Direct
Biological Process (BP) pathogenesis 0.00009392 Highly Informative Direct
Biological Process (BP) toxin metabolic process 0.0007787 Highly Informative Direct
Biological Process (BP) secondary metabolite biosynthetic process 0.03144 Highly Informative Inherited
Molecular Function (MF) transferase activity 0.1668 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.0000000000001419 Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) external encapsulating structure 0.002014 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.3899Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds0.07992Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases0.7751Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-CH group of donors0.00001928Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.01338Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.01038Moderately InformativeInherited
Enzyme Commission (EC)Enoyl-[acyl-carrier-protein] reductase (NADPH, B-s0InformativeDirect
Enzyme Commission (EC)3-hydroxypalmitoyl-[acyl-carrier-protein] dehydrat0InformativeDirect
Enzyme Commission (EC)Fatty-acid synthase0.0000000005256InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-acetyltransferase0.000000001939InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.000000002556InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-malonyltransferase0Highly InformativeDirect
Enzyme Commission (EC)3-oxoacyl-[acyl-carrier-protein] reductase0.00000000000001601Highly InformativeDirect
Enzyme Commission (EC)Beta-ketoacyl-acyl-carrier-protein synthase I0.000000000001198Highly InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.4576Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases0.8263Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors0.01263Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases0.05287Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.0000004982InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.008706InformativeInherited
Enzyme Commission (EC)Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)0Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-malonyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Beta-ketoacyl-[acyl-carrier-protein] synthase I0Highly InformativeDirect
Enzyme Commission (EC)Oleoyl-[acyl-carrier-protein] hydrolase0Highly InformativeDirect
Enzyme Commission (EC)3-oxoacyl-[acyl-carrier-protein] reductase0.00000000000002479Highly InformativeDirect
Enzyme Commission (EC)Fatty-acid synthase0.000000000532Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-acetyltransferase0.000000001965Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processLipid metabolism0Moderately InformativeDirect
Biological processFatty acid metabolism0InformativeDirect
Biological processLipid biosynthesis0.8152InformativeInherited
Biological processAntibiotic biosynthesis0Highly InformativeDirect
DomainCoiled coil0.0003083Moderately InformativeDirect
Molecular functionNADP0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationPhosphopantetheine0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)fatty acid metabolism0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)fatty acid biosynthesis0InformativeDirect
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)polyketide biosynthesis0.000000003282InformativeDirect
UniPathway (UP)toxin biosynthesis0.00000004482InformativeDirect
UniPathway (UP)mycotoxin biosynthesis0.00000001885Highly InformativeDirect
UniPathway (UP)bacillaene biosynthesis0.00001134Highly InformativeDirect
UniPathway (UP)erythromycin biosynthesis0.00012Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Probable ACP-binding domain of malonyl-CoA ACP transacylase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Probable ACP-binding domain of malonyl-CoA ACP transacylase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]