SUPERFAMILY 1.75 HMM library and genome assignments server

NTF2-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cystatin-like [ 54402] (7)
Superfamily:   NTF2-like [ 54427] (30)
Families:   Scytalone dehydratase [ 54428]
  NTF2-like [ 54431] (6)
  Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A [ 89851]
  Limonene-1,2-epoxide hydrolase-like [ 89854] (2)
  SnoaL-like polyketide cyclase [ 102810] (5)
  PhzA/PhzB-like [ 102813] (4)
  Ketosteroid isomerase-like [ 54434] (2)
  Ring hydroxylating beta subunit [ 54438] (6)
  Penicillin binding protein 2a (PBP2A), N-terminal domain [ 82595]
  Orange carotenoid protein, C-terminal domain [ 82598]
  Hypothetical protein egc068 from a soil-derived mobile gene cassette [ 110826]
  PA1314-like [ 110829]
  TIM44-like [ 143001]
  Sbal0622-like [ 159985]
  CHU142-like [ 159988]
  SO0125-like [ 159991] (2)
  SAV4671-like [ 159996]
  BxeB1374-like [ 159999] (2)
  Atu0744-like [ 160004]
  Rpa4348-like [ 160007] (2)
  Ava4193-like [ 160012]
  YybH-like [ 160015]
  PFL3262-like [ 160018]
  Exig0174-like [ 160021]
  Rv3472-like [ 160024] (2)
  VirB8-like [ 160029]
  ECA1476-like [ 160033]
  BaiE/LinA-like [ 160036] (5)
  Atu0742-like [ 160047]
  SEC-C associated NTF2-like domain [ 160050]


Superfamily statistics
Genomes (2,566) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 25,796 86,248 102
Proteins 25,278 84,109 102


Functional annotation
General category Processes_IC
Detailed category Transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)protein metabolic process10.01217Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.6241Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.99961Least InformativeInherited
Biological Process (BP)localization0.73590.005744Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.99051Least InformativeInherited
Biological Process (BP)cellular protein modification process0.66390.0000006434Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process10.000004257Moderately InformativeInherited
Biological Process (BP)organic substance transport0.11210.03108Moderately InformativeInherited
Biological Process (BP)cellular localization0.06970.000007343Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.016370.001958Moderately InformativeInherited
Biological Process (BP)ion transport0.26710.001681Moderately InformativeInherited
Biological Process (BP)system process0.38040.0007261Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.29461Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.92271Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.16481Moderately InformativeInherited
Biological Process (BP)muscle system process0.00026630.0001771InformativeDirect
Biological Process (BP)blood circulation0.00091620.000006408InformativeDirect
Biological Process (BP)cytoplasmic transport0.000074990.00003024InformativeDirect
Biological Process (BP)phosphorylation0.078820.00000000000005099InformativeInherited
Biological Process (BP)cell cycle process0.12370.0000004591InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.0036050.000000001179InformativeInherited
Biological Process (BP)nitrogen compound transport0.091090.00006268InformativeInherited
Biological Process (BP)metal ion transport0.044110.0001732InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.032911InformativeInherited
Biological Process (BP)regulation of immune response0.0042650.3328InformativeInherited
Biological Process (BP)regulation of immune effector process0.0017460.06399InformativeInherited
Biological Process (BP)mitotic cell cycle0.018920.000000000001339InformativeInherited
Biological Process (BP)regulation of production of molecular mediator of immune response0.0000043650.0003539Highly InformativeDirect
Biological Process (BP)regulation of humoral immune response0.0000018410.00005068Highly InformativeDirect
Biological Process (BP)calcium ion transport0.0001520Highly InformativeDirect
Biological Process (BP)striated muscle contraction0.000017440.00000000001019Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.000097940.0000000000001519Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00000005010.00000006936Highly InformativeDirect
Biological Process (BP)cell cycle phase0.000016220Highly InformativeDirect
Biological Process (BP)mitotic cell cycle phase transition0.000079020Highly InformativeDirect
Biological Process (BP)establishment of RNA localization0.000012020Highly InformativeDirect
Biological Process (BP)heart contraction0.00002310.000000000002869Highly InformativeDirect
Biological Process (BP)protein phosphorylation0.0130Highly InformativeInherited
Biological Process (BP)peptidyl-serine modification0.0024810Highly InformativeInherited
Biological Process (BP)nuclear export0.0073330.00000001704Highly InformativeInherited
Biological Process (BP)regulation of multi-organism process0.00016290.09842Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)enzyme binding0.0037290.6029InformativeInherited
Molecular Function (MF)Ras GTPase binding10.001577Highly InformativeInherited
Cellular Component (CC)protein complex10.8878Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)intracellular organelle part10.2332Least InformativeInherited
Cellular Component (CC)endomembrane system0.000083580.0000008546Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.59060.9582Moderately InformativeInherited
Cellular Component (CC)cell projection0.17410.2056Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.22830.3417Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0017040.00000000001827Moderately InformativeInherited
Cellular Component (CC)nuclear part0.013870.01311Moderately InformativeInherited
Cellular Component (CC)nuclear envelope0.0000000023670InformativeDirect
Cellular Component (CC)integral to membrane0.51650.8528InformativeInherited
Cellular Component (CC)neuron projection0.0072070.001405InformativeInherited
Cellular Component (CC)cell junction0.026460.06603InformativeInherited
Cellular Component (CC)sarcoplasmic reticulum0.0000020910.00000000001289Highly InformativeDirect
Cellular Component (CC)sarcolemma0.0000097670.00000001842Highly InformativeDirect
Cellular Component (CC)cell-cell contact zone0.0000012380.000000007074Highly InformativeDirect
Cellular Component (CC)main axon0.00000068340.0000000001054Highly InformativeDirect
Cellular Component (CC)pore complex0.00070170.00000001761Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) localization 0.005744 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.01217 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.6241 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) system process 0.0007261 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.0000006434 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.000004257 Moderately Informative Direct
Biological Process (BP) cellular localization 0.000007343 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 0.5433 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.001958 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.03108 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.8355 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.08468 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.009172 Moderately Informative Inherited
Biological Process (BP) ion transport 0.001681 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) mitotic cell cycle 0.000000000001339 Informative Direct
Biological Process (BP) muscle system process 0.0001771 Informative Direct
Biological Process (BP) mitochondrion organization 0.0006965 Informative Direct
Biological Process (BP) blood circulation 0.000006408 Informative Direct
Biological Process (BP) phosphorylation 0.00000000000005099 Informative Direct
Biological Process (BP) cytoplasmic transport 0.00003024 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0.000000001179 Informative Direct
Biological Process (BP) cell cycle process 0.0000004591 Informative Direct
Biological Process (BP) metal ion transport 0.0001732 Informative Direct
Biological Process (BP) regulation of ion transport 0.000000004609 Informative Direct
Biological Process (BP) regulation of system process 0.00000000002036 Informative Direct
Biological Process (BP) nitrogen compound transport 0.00006268 Informative Direct
Biological Process (BP) regulation of apoptotic signaling pathway 0.000005038 Informative Direct
Biological Process (BP) positive regulation of signal transduction 0.08199 Informative Inherited
Biological Process (BP) protein transport 0.9778 Informative Inherited
Biological Process (BP) transmembrane transport 0.5401 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.2247 Informative Inherited
Biological Process (BP) sexual reproduction 0.2308 Informative Inherited
Biological Process (BP) single organism reproductive process 0.3601 Informative Inherited
Biological Process (BP) cellular membrane organization 0.3248 Informative Inherited
Biological Process (BP) response to inorganic substance 0.001844 Informative Inherited
Biological Process (BP) regulation of cell cycle process 0.004298 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.006118 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.005741 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.0191 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.2931 Informative Inherited
Biological Process (BP) apoptotic process 0.527 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of immune response 0.3328 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.06399 Informative Inherited
Biological Process (BP) regulation of production of molecular mediator of immune response 0.0003539 Highly Informative Direct
Biological Process (BP) regulation of humoral immune response 0.00005068 Highly Informative Direct
Biological Process (BP) protein phosphorylation 0 Highly Informative Direct
Biological Process (BP) calcium ion transport 0 Highly Informative Direct
Biological Process (BP) mitochondrial transport 0.00003759 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.00000000001019 Highly Informative Direct
Biological Process (BP) mitochondrial membrane organization 0.00002307 Highly Informative Direct
Biological Process (BP) regulation of G-protein coupled receptor protein signaling pathway 0.0000000003875 Highly Informative Direct
Biological Process (BP) fertilization 0.000000009714 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.0000000000001519 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.00000006936 Highly Informative Direct
Biological Process (BP) peptidyl-serine modification 0 Highly Informative Direct
Biological Process (BP) cell cycle phase 0 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0 Highly Informative Direct
Biological Process (BP) response to cadmium ion 0.00002209 Highly Informative Direct
Biological Process (BP) regulation of synaptic transmission 0.0000000000004438 Highly Informative Direct
Biological Process (BP) neuromuscular process 0.00000001681 Highly Informative Direct
Biological Process (BP) nuclear export 0.00000001704 Highly Informative Direct
Biological Process (BP) establishment of RNA localization 0 Highly Informative Direct
Biological Process (BP) heart contraction 0.000000000002869 Highly Informative Direct
Biological Process (BP) positive regulation of cell cycle process 0.0000007394 Highly Informative Direct
Biological Process (BP) regulation of reproductive process 0.000008938 Highly Informative Direct
Biological Process (BP) positive regulation of apoptotic signaling pathway 0.0000000004877 Highly Informative Direct
Biological Process (BP) positive regulation of programmed cell death 0.3797 Highly Informative Inherited
Biological Process (BP) regulation of multi-organism process 0.09842 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.00302 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.000000002724 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.5281 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.00001342 Informative Direct
Molecular Function (MF) kinase activity 0.00000000002278 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.00003627 Informative Direct
Molecular Function (MF) receptor binding 0.7608 Informative Inherited
Molecular Function (MF) enzyme binding 0.6029 Informative Inherited
Molecular Function (MF) protein kinase activity 0.0000003447 Highly Informative Direct
Molecular Function (MF) Ras GTPase binding 0.001577 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.8878 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.2332 Least Informative Inherited
Cellular Component (CC) endomembrane system 0.0000008546 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.00000000001827 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 0.9582 Moderately Informative Inherited
Cellular Component (CC) cell projection 0.2056 Moderately Informative Inherited
Cellular Component (CC) plasma membrane 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.9871 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.3417 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 0.7238 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.01311 Moderately Informative Inherited
Cellular Component (CC) nuclear envelope 0 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0.05358 Informative Inherited
Cellular Component (CC) integral to membrane 0.8528 Informative Inherited
Cellular Component (CC) neuron projection 0.001405 Informative Inherited
Cellular Component (CC) nucleoplasm part 0.5153 Informative Inherited
Cellular Component (CC) cell junction 0.06603 Informative Inherited
Cellular Component (CC) spindle 0.000003815 Highly Informative Direct
Cellular Component (CC) sarcoplasmic reticulum 0.00000000001289 Highly Informative Direct
Cellular Component (CC) sarcolemma 0.00000001842 Highly Informative Direct
Cellular Component (CC) cell-cell contact zone 0.000000007074 Highly Informative Direct
Cellular Component (CC) main axon 0.0000000001054 Highly Informative Direct
Cellular Component (CC) pore complex 0.00000001761 Highly Informative Direct
Cellular Component (CC) nuclear body 0.03219 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.0002027Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.0006578Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.000000002583Moderately InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)fertile0Moderately InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0.2631Least InformativeInherited
Xenopus ANatomical entity (XAN)germ cell0.0003959Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.00002444Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups0.0002943Least InformativeDirect
Enzyme Commission (EC)Hydrolases0.3832Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.00000001191Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0.2699Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases0.4074Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.6071Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA helicase0.0007127InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases0.1618InformativeInherited
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor0Highly InformativeDirect
Enzyme Commission (EC)Transposing C==C bonds0.0001374Highly InformativeDirect
Enzyme Commission (EC)Intramolecular lyases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0.0000000000001263Moderately InformativeDirect
Biological processDifferentiation0.0001511Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0InformativeDirect
Biological processVirulence0.00000001658InformativeDirect
Biological processNeurogenesis0.0000001616InformativeDirect
Biological processmRNA transport0Highly InformativeDirect
Biological processAntibiotic biosynthesis0.000000000000001398Highly InformativeDirect
Cellular componentNucleus0.0000001648Least InformativeDirect
Cellular componentMitochondrion0.00003236Moderately InformativeDirect
Cellular componentSarcoplasmic reticulum0Highly InformativeDirect
DomainTransit peptide0.0000001008Moderately InformativeDirect
DomainLeucine-rich repeat6.161e-16InformativeDirect
Molecular functionNAD0.000000006415Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationKinase0.000003737Moderately InformativeDirect
Post-translational modificationOxidoreductase0.003419Moderately InformativeInherited
Post-translational modificationSerine/threonine-protein kinase0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationPhosphoprotein0.00000003454Least InformativeDirect
Post-translational modificationAcetylation0.000007636Least InformativeDirect
Post-translational modificationNitration0.000000009028InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.000008534Least InformativeDirect
UniPathway (UP)aromatic compound degradation0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0.00000001571Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0.001585Moderately InformativeInherited
UniPathway (UP)polyketide biosynthesis0.000001101InformativeDirect
UniPathway (UP)antibiotic biosynthesis0.00002746InformativeDirect
UniPathway (UP)phenylpropanoid degradation0.0005041InformativeDirect
UniPathway (UP)sucrose biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 67 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a NTF2-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 67 hidden Markov models representing the NTF2-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]