SUPERFAMILY 1.75 HMM library and genome assignments server

"Helical backbone" metal receptor superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Chelatase-like [ 53799] (3)
Superfamily:   "Helical backbone" metal receptor [ 53807] (4)
Families:   Periplasmic ferric siderophore binding protein FhuD [ 53808]
  TroA-like [ 53811] (5)
  Nitrogenase iron-molybdenum protein [ 53816] (2)
  TM0189-like [ 142789] (3)


Superfamily statistics
Genomes (2,613) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 15,128 106,017 23
Proteins 15,073 105,896 23


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization0.0000014930.00004049Least InformativeDirect
Biological Process (BP)single-organism cellular process0.010380.09766Least InformativeInherited
Biological Process (BP)ion transport0.020410.03214Moderately InformativeInherited
Biological Process (BP)transmembrane transport0.000000001380.00000000006123InformativeDirect
Biological Process (BP)metal ion transport0.025240.1698InformativeInherited
Biological Process (BP)transition metal ion transport0.00000000001140.00000000002594Highly InformativeDirect
Molecular Function (MF)hydrolase activity0.0000072720.00001286Least InformativeDirect
Molecular Function (MF)transporter activity0.0000000000087170.000000000121Moderately InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances0.00000000063880.0000000001321InformativeDirect
Molecular Function (MF)nucleoside-triphosphatase activity0.0000000000031780.00000000006018InformativeDirect
Molecular Function (MF)active transmembrane transporter activity0.00011930.000006885InformativeDirect
Molecular Function (MF)metal ion transmembrane transporter activity0.0018920.06152InformativeInherited
Molecular Function (MF)transition metal ion transmembrane transporter activity0.00000000000026170.00000000000355Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.00004049 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.09766 Least Informative Inherited
Biological Process (BP) ion transport 0.03214 Moderately Informative Inherited
Biological Process (BP) transmembrane transport 0.00000000006123 Informative Direct
Biological Process (BP) metal ion transport 0.1698 Informative Inherited
Biological Process (BP) transition metal ion transport 0.00000000002594 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.00001286 Least Informative Direct
Molecular Function (MF) transporter activity 0.000000000121 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.0000000001321 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0.00000000006018 Informative Direct
Molecular Function (MF) active transmembrane transporter activity 0.000006885 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.06152 Informative Inherited
Molecular Function (MF) transition metal ion transmembrane transporter activity 0.00000000000355 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on iron-sulfur proteins as donors0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on iron-sulfur proteins as donors0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.0006214Least InformativeDirect
Biological processNitrogen fixation0InformativeDirect
Biological processPhotosynthesis0InformativeDirect
Biological processChlorophyll biosynthesis0Highly InformativeDirect
Cellular componentPlastid0Moderately InformativeDirect
Cellular componentPeriplasm0InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc1Least InformativeInherited
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionMolybdenum0InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Molecular functionZinc transport0Highly InformativeDirect
Molecular functionIron transport0.00009645Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationPalmitate0.0000001042Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)porphyrin-containing compound metabolism0Moderately InformativeDirect
UniPathway (UP)heterocycle biosynthesis0InformativeDirect
UniPathway (UP)pigment biosynthesis0InformativeDirect
UniPathway (UP)chlorophyll biosynthesis (light-independent)0Highly InformativeDirect
UniPathway (UP)bacteriochlorophyll biosynthesis (light-independent)0Highly InformativeDirect
UniPathway (UP)bacteriochlorophyll biosynthesis0.0001079Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a "Helical backbone" metal receptor domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 15 hidden Markov models representing the "Helical backbone" metal receptor superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]