SUPERFAMILY 1.75 HMM library and genome assignments server

Chelatase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Chelatase-like [ 53799] (3)
Superfamily:   Chelatase [ 53800] (3)
Families:   Ferrochelatase [ 53801]
  Cobalt chelatase CbiK [ 53804]
  CbiX-like [ 110742]


Superfamily statistics
Genomes (2,726) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,599 24,067 8
Proteins 4,507 23,795 8


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.00012260.00000000000007678Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.00074280.000000000003264Least InformativeDirect
Biological Process (BP)biosynthetic process0.00026070.00000000000001953Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.00011770.00000000000005424Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.00025560.0000000000003851Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.014020.00000005479Least InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.00000010490Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process0.000000050050Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process0.000000091580Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.0000051960Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.00000028370Moderately InformativeDirect
Biological Process (BP)organonitrogen compound biosynthetic process0.00000026990Moderately InformativeDirect
Biological Process (BP)pigment metabolic process0.0000026660InformativeDirect
Biological Process (BP)pigment biosynthetic process0.000011720Highly InformativeDirect
Molecular Function (MF)binding0.63160.7088Least InformativeInherited
Molecular Function (MF)lyase activity0.000000000012690Moderately InformativeDirect
Molecular Function (MF)cation binding0.0023310.0000000005053Moderately InformativeInherited
Molecular Function (MF)tetrapyrrole binding0.0000014020InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.00000000000007678 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.000000000003264 Least Informative Direct
Biological Process (BP) biosynthetic process 0.00000000000001953 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.00000005479 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.00000000000005424 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000000000003851 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.6453 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.07565 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.2476 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.505 Least Informative Inherited
Biological Process (BP) developmental process 0.3638 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.0926 Least Informative Inherited
Biological Process (BP) immune system process 0.0002819 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.00005335 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.0002286 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.00007147 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0007897 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.0003693 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.0001369 Moderately Informative Direct
Biological Process (BP) organ development 0.01505 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.02655 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.03428 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.0151 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.02226 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.004348 Moderately Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.000006629 Informative Direct
Biological Process (BP) alcohol metabolic process 0.0004848 Informative Direct
Biological Process (BP) response to light stimulus 0.000000001555 Informative Direct
Biological Process (BP) pigment metabolic process 0 Informative Direct
Biological Process (BP) hematopoietic or lymphoid organ development 0.00000007636 Informative Direct
Biological Process (BP) cation homeostasis 0.0000005114 Informative Direct
Biological Process (BP) porphyrin-containing compound biosynthetic process 0.0000000004633 Highly Informative Direct
Biological Process (BP) detection of light stimulus 0.000007922 Highly Informative Direct
Biological Process (BP) sterol metabolic process 0.0000000001016 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 0.00000000000003126 Highly Informative Direct
Biological Process (BP) heme metabolic process 0.00000000001885 Highly Informative Direct
Biological Process (BP) pigment biosynthetic process 0 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 0.0000000002978 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.000000009549 Highly Informative Direct
Biological Process (BP) response to UV 0.005181 Highly Informative Inherited
Molecular Function (MF) binding 0.7088 Least Informative Inherited
Molecular Function (MF) lyase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0.0000000005053 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.7323 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.000007428 Informative Direct
Molecular Function (MF) tetrapyrrole binding 0 Informative Direct
Molecular Function (MF) iron ion binding 0.00002706 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.001905 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.0181 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.1727 Least Informative Inherited
Cellular Component (CC) membrane 0.03706 Least Informative Inherited
Cellular Component (CC) organelle membrane 0.0000222 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.0000009299 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.000000000852 Moderately Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for lyases that do not belong in1InformativeInherited

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cotyledon0Moderately InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for lyases that do not belong in the other subclasses1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHeme biosynthesis0Highly InformativeDirect
Biological processPorphyrin biosynthesis0Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionCobalt0.0000000000005783InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0Least InformativeDirect
UniPathway (UP)porphyrin-containing compound metabolism0Moderately InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Chelatase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Chelatase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]