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• Structural
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Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001

	GO term	FDR (all)	IC level	SDFO level	Annotation (direct or inherited)
Biological Process (BP)	regulation of defense response	0	1.658	--	DIRECT
Biological Process (BP)	positive regulation of response to stimulus	0	1.284	--	DIRECT
Biological Process (BP)	biological regulation	0	0.4202	--	DIRECT
Biological Process (BP)	interaction with host	0	2.222	--	DIRECT
Biological Process (BP)	regulation of sequence-specific DNA binding transcription factor activity	0	1.854	--	DIRECT
Biological Process (BP)	activation of innate immune response	0	2.699	--	DIRECT
Biological Process (BP)	macrophage activation	0	2.699	--	DIRECT
Biological Process (BP)	positive regulation of cytokine biosynthetic process	0	2.398	--	DIRECT
Biological Process (BP)	response to molecule of bacterial origin	0	2.222	--	DIRECT
Biological Process (BP)	negative regulation of growth of symbiont involved in interaction with host	0	2.699	--	DIRECT
Biological Process (BP)	positive regulation of defense response	0	2.398	--	DIRECT
Biological Process (BP)	negative regulation of multi-organism process	0	2.398	--	DIRECT
Biological Process (BP)	signaling	0	0.8416	--	DIRECT
Biological Process (BP)	regulation of biological process	0	0.4486	--	DIRECT
Biological Process (BP)	positive regulation of innate immune response	0	2.699	--	DIRECT
Biological Process (BP)	regulation of I-kappaB kinase/NF-kappaB cascade	0	2.699	--	DIRECT
Biological Process (BP)	positive regulation of immune response	0	1.796	--	DIRECT
Biological Process (BP)	regulation of growth of symbiont in host	0	2.699	--	DIRECT
Biological Process (BP)	modification of morphology or physiology of other organism involved in symbiotic interaction	0	2.222	--	DIRECT
Biological Process (BP)	cell communication	0	0.8477	--	DIRECT
Biological Process (BP)	innate immune response-activating signal transduction	0	2.699	--	DIRECT
Biological Process (BP)	modulation of growth of symbiont involved in interaction with host	0	2.699	--	DIRECT
Biological Process (BP)	positive regulation of NF-kappaB transcription factor activity	0	2.222	--	DIRECT
Biological Process (BP)	regulation of JNK cascade	0	2.398	--	DIRECT
Biological Process (BP)	regulation of immune system process	0	1.398	--	DIRECT
Biological Process (BP)	response to biotic stimulus	0	1.377	--	DIRECT
Biological Process (BP)	negative regulation of growth of symbiont in host	0	2.699	--	DIRECT
Biological Process (BP)	single organism signaling	0	0.8601	--	DIRECT
Biological Process (BP)	modification by symbiont of host morphology or physiology	0	2.699	--	DIRECT
Biological Process (BP)	positive regulation of cellular metabolic process	2.076e-15	1.208	--	DIRECT
Biological Process (BP)	positive regulation of biological process	2.076e-15	0.8182	--	DIRECT
Biological Process (BP)	positive regulation of tumor necrosis factor production	5.966e-15	2.699	--	DIRECT
Biological Process (BP)	detection of chemical stimulus	1.53e-14	2.398	--	DIRECT
Biological Process (BP)	cytokine production	1.019e-13	2.699	--	DIRECT
Biological Process (BP)	positive regulation of mononuclear cell proliferation	1.516e-13	2.398	--	DIRECT
Biological Process (BP)	positive regulation of biosynthetic process	2.164e-11	1.495	--	DIRECT
Biological Process (BP)	adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli	2.371e-11	2.398	--	DIRECT
Biological Process (BP)	response to stress	3.353e-11	0.8125	--	DIRECT
Biological Process (BP)	negative regulation of growth	5.693e-11	1.854	--	DIRECT
Biological Process (BP)	lipopolysaccharide-mediated signaling pathway	7.042e-11	2.398	--	DIRECT
Biological Process (BP)	regulation of symbiosis, encompassing mutualism through parasitism	9.228e-11	2.699	--	DIRECT
Biological Process (BP)	cellular response to mechanical stimulus	1.453e-10	2.699	--	DIRECT
Biological Process (BP)	Toll signaling pathway	7.814e-10	2.699	--	DIRECT
Biological Process (BP)	response to exogenous dsRNA	8.524e-10	2.699	--	DIRECT
Biological Process (BP)	response to molecule of fungal origin	3.249e-09	2.699	--	DIRECT
Biological Process (BP)	regulation of transcription factor import into nucleus	3.375e-09	2.699	--	DIRECT
Biological Process (BP)	cellular response to stimulus	5.276e-09	0.7645	--	DIRECT
Biological Process (BP)	regulation of leukocyte proliferation	7.197e-09	2.222	--	DIRECT
Biological Process (BP)	positive regulation of nucleocytoplasmic transport	7.39e-09	2.699	--	DIRECT
Biological Process (BP)	regulation of chemokine production	1.469e-08	2.699	--	DIRECT
Biological Process (BP)	single-organism process	1.813e-08	0.3316	--	DIRECT
Biological Process (BP)	immunoglobulin mediated immune response	5.121e-08	2.699	--	DIRECT
Biological Process (BP)	regulation of interleukin-6 production	7.952e-08	2.398	--	DIRECT
Biological Process (BP)	regulation of establishment of protein localization	8.462e-08	1.62	--	DIRECT
Biological Process (BP)	regulation of tumor necrosis factor production	1.769e-07	2.699	--	DIRECT
Biological Process (BP)	detection of stimulus	2.523e-07	1.854	--	DIRECT
Biological Process (BP)	regulation of production of molecular mediator of immune response	2.655e-07	2.398	--	DIRECT
Biological Process (BP)	positive regulation of toll-like receptor signaling pathway	3.007e-07	2.699	--	DIRECT
Biological Process (BP)	positive regulation of macromolecule metabolic process	3.194e-07	1.301	--	DIRECT
Biological Process (BP)	lymphocyte mediated immunity	4.019e-07	2.398	--	DIRECT
Biological Process (BP)	regulation of protein import into nucleus	6.964e-07	2.222	--	DIRECT
Biological Process (BP)	positive regulation of nitric oxide biosynthetic process	1.6e-06	2.699	--	DIRECT
Biological Process (BP)	positive regulation of cytokine secretion	2.914e-06	2.699	--	DIRECT
Biological Process (BP)	biological_process	4.117e-06	0	--	DIRECT
Biological Process (BP)	regulation of protein serine/threonine kinase activity	4.173e-06	1.854	--	DIRECT
Biological Process (BP)	male gonad development	4.199e-06	2.699	--	DIRECT
Biological Process (BP)	defense response to bacterium	4.356e-06	2.097	--	DIRECT
Biological Process (BP)	regulation of autophagy	7.376e-06	2.398	--	DIRECT
Biological Process (BP)	cellular response to lipopolysaccharide	1.53e-05	2.222	--	DIRECT
Biological Process (BP)	development of primary male sexual characteristics	2.553e-05	2.398	--	DIRECT
Biological Process (BP)	regulation of stress-activated MAPK cascade	2.866e-05	2.398	--	DIRECT
Biological Process (BP)	response to mechanical stimulus	3.265e-05	2.699	--	DIRECT
Biological Process (BP)	male sex differentiation	3.912e-05	2.398	--	DIRECT
Biological Process (BP)	positive regulation of lymphocyte proliferation	3.971e-05	2.398	--	DIRECT
Biological Process (BP)	positive regulation of transferase activity	4.351e-05	1.854	--	DIRECT
Biological Process (BP)	regulation of protein modification process	5.273e-05	1.377	--	DIRECT
Biological Process (BP)	regulation of cell activation	5.901e-05	1.854	--	DIRECT
Biological Process (BP)	cellular response to molecule of bacterial origin	6.73e-05	2.222	--	DIRECT
Biological Process (BP)	regulation of toll-like receptor signaling pathway	6.736e-05	2.699	--	DIRECT
Biological Process (BP)	positive regulation of production of molecular mediator of immune response	7.168e-05	2.699	--	DIRECT
Biological Process (BP)	regulation of phosphorylation	8.09e-05	1.469	--	DIRECT
Biological Process (BP)	positive regulation of cell communication	8.959e-05	1.377	--	DIRECT
Biological Process (BP)	regulation of stress-activated protein kinase signaling cascade	0.0001003	2.398	--	DIRECT
Biological Process (BP)	positive regulation of phosphate metabolic process	0.0001082	1.699	--	DIRECT
Biological Process (BP)	regulation of transferase activity	0.0001709	1.62	--	DIRECT
Biological Process (BP)	response to bacterium	0.0001719	1.658	--	DIRECT
Biological Process (BP)	positive regulation of intracellular protein kinase cascade	0.0001788	1.658	--	DIRECT
Biological Process (BP)	myeloid cell differentiation	0.0001911	2.097	--	DIRECT
Biological Process (BP)	regulation of protein transport	0.0001954	1.658	--	DIRECT
Biological Process (BP)	intracellular protein kinase cascade	0.0001955	1.745	--	DIRECT
Biological Process (BP)	regulation of neuron projection development	0.0002088	2.398	--	DIRECT
Biological Process (BP)	activation of MAPK activity	0.0003656	2.398	--	DIRECT
Biological Process (BP)	positive regulation of cell motility	0.0004763	1.921	--	DIRECT
Biological Process (BP)	regulation of interleukin-8 production	0.0006578	2.398	--	DIRECT
Biological Process (BP)	cellular process	0.000756	0.1415	--	DIRECT
Biological Process (BP)	regulation of response to biotic stimulus	0.007436	2.699	--	INHERITED FROM: regulation of defense response to fungus || regulation of antifungal peptide production || positive regulation of antifungal peptide biosynthetic process || regulation of antifungal peptide biosynthetic process || regulation of antimicrobial humoral response || positive regulation of antimicrobial peptide biosynthetic process || regulation of antimicrobial peptide biosynthetic process
Biological Process (BP)	cellular response to external stimulus	0.04079	1.921	--	INHERITED FROM: cellular response to mechanical stimulus
Biological Process (BP)	positive regulation of cell proliferation	0.5662	1.658	--	INHERITED FROM: positive regulation of leukocyte proliferation || positive regulation of mononuclear cell proliferation || positive regulation of lymphocyte proliferation
Biological Process (BP)	positive regulation of cytokine production involved in immune response	0.00693	2.699	--	INHERITED FROM: positive regulation of macrophage cytokine production || positive regulation of myeloid leukocyte cytokine production involved in immune response
Biological Process (BP)	regulation of cytokine production involved in immune response	0.1165	2.398	--	INHERITED FROM: positive regulation of macrophage cytokine production || regulation of macrophage cytokine production || positive regulation of myeloid leukocyte cytokine production involved in immune response
Biological Process (BP)	regulation of biological quality	1	0.8539	--	INHERITED FROM: modulation by symbiont of host innate immune response || modulation by symbiont of host defense response || positive regulation by organism of immune response of other organism involved in symbiotic interacti || modification of morphology or physiology of other organism || modification of morphology or physiology of other organism involved in symbiotic interaction || positive regulation by organism of defense response of other organism involved in symbiotic interact || pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune respons || positive regulation by symbiont of host defense response || modulation by organism of immune response of other organism involved in symbiotic interaction || pathogen-associated molecular pattern dependent modulation by organism of innate immune response in || positive regulation by organism of innate immune response in other organism involved in symbiotic in || modulation by organism of innate immune response in other organism involved in symbiotic interaction || positive regulation by symbiont of host immune response || modulation by organism of defense response of other organism involved in symbiotic interaction || modulation by symbiont of host immune response || positive regulation by symbiont of host innate immune response || modification by symbiont of host morphology or physiology
Biological Process (BP)	interspecies interaction between organisms	0.6416	1.796	--	INHERITED FROM: modulation by symbiont of host innate immune response || symbiosis, encompassing mutualism through parasitism || modulation by symbiont of host defense response || positive regulation by organism of immune response of other organism involved in symbiotic interacti || response to host defenses || response to immune response of other organism involved in symbiotic interaction || modification of morphology or physiology of other organism involved in symbiotic interaction || positive regulation by organism of defense response of other organism involved in symbiotic interact || pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune respons || positive regulation by symbiont of host defense response || modulation by organism of immune response of other organism involved in symbiotic interaction || pathogen-associated molecular pattern dependent modulation by organism of innate immune response in || positive regulation by organism of innate immune response in other organism involved in symbiotic in || interaction with host || response to host immune response || modulation by organism of innate immune response in other organism involved in symbiotic interaction || positive regulation by symbiont of host immune response || modulation by organism of defense response of other organism involved in symbiotic interaction || modulation by symbiont of host immune response || positive regulation by symbiont of host innate immune response || response to host || modification by symbiont of host morphology or physiology
Biological Process (BP)	regulation of macromolecule metabolic process	1	0.7959	--	INHERITED FROM: regulation of nitric-oxide synthase biosynthetic process || regulation of sequence-specific DNA binding transcription factor activity || regulation of protein metabolic process || positive regulation of cytokine biosynthetic process || regulation of interferon-beta biosynthetic process || positive regulation of protein metabolic process || positive regulation of interferon-beta biosynthetic process || regulation of interferon-gamma biosynthetic process || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || regulation of interferon-alpha biosynthetic process || positive regulation of nitric-oxide synthase biosynthetic process || activation of MAPK activity || positive regulation of macromolecule metabolic process || regulation of cytokine biosynthetic process || positive regulation of protein serine/threonine kinase activity || regulation of protein modification process || positive regulation of interferon-alpha biosynthetic process || positive regulation of interferon-gamma biosynthetic process || positive regulation of macromolecule biosynthetic process || positive regulation of NF-kappaB transcription factor activity || regulation of chemokine biosynthetic process
Biological Process (BP)	regulation of macromolecule biosynthetic process	0.02165	1.066	--	INHERITED FROM: regulation of nitric-oxide synthase biosynthetic process || regulation of sequence-specific DNA binding transcription factor activity || regulation of cytokine biosynthetic process || positive regulation of cytokine biosynthetic process || regulation of interferon-beta biosynthetic process || positive regulation of interferon-alpha biosynthetic process || positive regulation of interferon-gamma biosynthetic process || positive regulation of interferon-beta biosynthetic process || regulation of interferon-gamma biosynthetic process || positive regulation of macromolecule biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity || regulation of chemokine biosynthetic process || regulation of interferon-alpha biosynthetic process || positive regulation of nitric-oxide synthase biosynthetic process
Biological Process (BP)	regulation of transport	0.06173	1.155	--	INHERITED FROM: regulation of protein transport || positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || regulation of nucleocytoplasmic transport || positive regulation of protein transport || positive regulation of protein import into nucleus || regulation of protein import into nucleus || positive regulation of cytokine secretion || regulation of transcription factor import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	positive regulation of molecular function	0.005439	1.222	--	INHERITED FROM: positive regulation of NF-kappaB transcription factor activity || activation of MAPK activity || positive regulation of protein serine/threonine kinase activity || positive regulation of transferase activity || positive regulation of sequence-specific DNA binding transcription factor activity
Biological Process (BP)	regulation of primary metabolic process	1	0.7852	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || regulation of protein metabolic process || positive regulation of cytokine biosynthetic process || regulation of interferon-beta biosynthetic process || positive regulation of protein metabolic process || positive regulation of interferon-beta biosynthetic process || regulation of interferon-gamma biosynthetic process || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || regulation of interferon-alpha biosynthetic process || activation of MAPK activity || regulation of cytokine biosynthetic process || positive regulation of protein serine/threonine kinase activity || regulation of protein modification process || positive regulation of interferon-alpha biosynthetic process || positive regulation of interferon-gamma biosynthetic process || positive regulation of NF-kappaB transcription factor activity || regulation of chemokine biosynthetic process
Biological Process (BP)	regulation of transcription, DNA-dependent	0.06051	1.237	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of nucleobase-containing compound metabolic process	1	1.027	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of cellular macromolecule biosynthetic process	1	1.119	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of RNA metabolic process	1	1.131	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of RNA biosynthetic process	1	1.167	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of cellular biosynthetic process	0.02036	1.009	--	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of cytokine biosynthetic process || regulation of interferon-beta biosynthetic process || regulation of antimicrobial peptide biosynthetic process || positive regulation of interferon-beta biosynthetic process || regulation of antifungal peptide biosynthetic process || regulation of interferon-gamma biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || regulation of interferon-alpha biosynthetic process || regulation of cytokine biosynthetic process || positive regulation of cellular biosynthetic process || positive regulation of antifungal peptide biosynthetic process || positive regulation of antimicrobial peptide biosynthetic process || positive regulation of interferon-alpha biosynthetic process || positive regulation of interferon-gamma biosynthetic process || regulation of nitric oxide biosynthetic process || positive regulation of NF-kappaB transcription factor activity || regulation of chemokine biosynthetic process
Biological Process (BP)	positive regulation of protein secretion	0.01681	2.222	--	INHERITED FROM: positive regulation of cytokine secretion
Biological Process (BP)	regulation of cytokine secretion	1	2.222	--	INHERITED FROM: positive regulation of cytokine secretion
Biological Process (BP)	regulation of lymphocyte proliferation	0.001167	2.398	--	INHERITED FROM: positive regulation of lymphocyte proliferation
Biological Process (BP)	positive regulation of lymphocyte activation	0.01085	2.222	--	INHERITED FROM: positive regulation of lymphocyte proliferation
Biological Process (BP)	regulation of leukocyte activation	1	1.921	--	INHERITED FROM: positive regulation of lymphocyte proliferation
Biological Process (BP)	positive regulation of leukocyte activation	1	2.097	--	INHERITED FROM: positive regulation of lymphocyte proliferation
Biological Process (BP)	multicellular organismal development	1	0.7496	--	INHERITED FROM: regulation of dendrite morphogenesis || development of primary male sexual characteristics || gonad development || male gonad development || regulation of neuron projection development || myeloid cell differentiation || male sex differentiation
Biological Process (BP)	system development	0.6999	0.8069	--	INHERITED FROM: regulation of dendrite morphogenesis || gonad development || male gonad development || regulation of neuron projection development || myeloid cell differentiation
Biological Process (BP)	anatomical structure development	0.7618	0.7212	--	INHERITED FROM: regulation of dendrite morphogenesis || gonad development || male gonad development || regulation of neuron projection development || myeloid cell differentiation
Biological Process (BP)	single-multicellular organism process	1	0.6383	--	INHERITED FROM: regulation of dendrite morphogenesis || cytokine production || development of primary male sexual characteristics || regulation of neuron projection development || cytokine biosynthetic process || male sex differentiation || gonad development || male gonad development || type I interferon production || myeloid cell differentiation
Biological Process (BP)	regulation of cell morphogenesis involved in differentiation	0.06802	2.222	--	INHERITED FROM: regulation of dendrite morphogenesis
Biological Process (BP)	regulation of cellular localization	0.01819	1.357	--	INHERITED FROM: positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || regulation of protein import into nucleus || regulation of nucleocytoplasmic transport || positive regulation of cytokine secretion || regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	reproductive process	1	1.143	--	INHERITED FROM: male sex differentiation || development of primary male sexual characteristics || male gonad development || gonad development
Biological Process (BP)	negative regulation of biological process	1	0.8665	--	INHERITED FROM: negative regulation of growth of symbiont involved in interaction with host || negative regulation of interleukin-17 production || negative regulation of multi-organism process || negative regulation of growth || negative regulation of growth of symbiont in host
Biological Process (BP)	response to dsRNA	0.02855	2.699	--	INHERITED FROM: response to exogenous dsRNA
Biological Process (BP)	positive regulation of intracellular protein transport	0.01147	2.699	--	INHERITED FROM: positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of NF-kappaB import into nucleus	0.0727	2.699	--	INHERITED FROM: positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	organic substance metabolic process	1	0.2676	--	INHERITED FROM: cytokine metabolic process || cytokine biosynthetic process || activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	metabolic process	1	0.2411	--	INHERITED FROM: cytokine metabolic process || cytokine biosynthetic process || activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	negative regulation of cytokine production	0.7797	2.398	--	INHERITED FROM: negative regulation of interleukin-17 production
Biological Process (BP)	response to nitrogen compound	0.008842	1.377	--	INHERITED FROM: response to peptidoglycan || response to exogenous dsRNA
Biological Process (BP)	cellular response to lipid	0.01823	1.745	--	INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to lipopolysaccharide
Biological Process (BP)	regulation of cell motility	0.01593	1.745	--	INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility
Biological Process (BP)	positive regulation of cellular component movement	0.2319	1.854	--	INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility
Biological Process (BP)	positive regulation of locomotion	0.5351	1.854	--	INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility
Biological Process (BP)	regulation of cell migration	0.01322	1.745	--	INHERITED FROM: positive regulation of cell migration
Biological Process (BP)	hemopoiesis	0.003055	1.699	--	INHERITED FROM: myeloid cell differentiation
Biological Process (BP)	immune system development	1	1.585	--	INHERITED FROM: myeloid cell differentiation
Biological Process (BP)	cellular response to organic substance	0.05088	1.208	--	INHERITED FROM: cytokine-mediated signaling pathway || cellular response to lipopolysaccharide || lipopolysaccharide-mediated signaling pathway
Biological Process (BP)	response to chemical stimulus	0.2969	0.8861	--	INHERITED FROM: cytokine-mediated signaling pathway || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound || response to lipoteichoic acid || cellular response to lipopolysaccharide || detection of chemical stimulus || response to exogenous dsRNA || response to lipopolysaccharide || response to oxygen-containing compound || response to bacterial lipoprotein || response to organic substance || response to molecule of fungal origin || cellular response to molecule of bacterial origin || detection of lipopolysaccharide || response to molecule of bacterial origin || cellular response to bacterial lipoprotein || detection of molecule of bacterial origin || cellular response to lipoteichoic acid || response to peptidoglycan
Biological Process (BP)	cell surface receptor signaling pathway	0.9531	1.237	--	INHERITED FROM: cytokine-mediated signaling pathway || innate immune response activating cell surface receptor signaling pathway || Toll signaling pathway || lipopolysaccharide-mediated signaling pathway
Biological Process (BP)	cellular response to cytokine stimulus	0.01229	1.745	--	INHERITED FROM: cytokine-mediated signaling pathway
Biological Process (BP)	adaptive immune response	1	2.398	--	INHERITED FROM: immunoglobulin mediated immune response || adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli
Biological Process (BP)	B cell mediated immunity	0.662	2.699	--	INHERITED FROM: immunoglobulin mediated immune response
Biological Process (BP)	cellular developmental process	1	0.9666	--	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis || myeloid cell differentiation
Biological Process (BP)	regulation of neurogenesis	0.005724	1.699	--	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	neurogenesis	0.1881	1.357	--	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	regulation of cell differentiation	1	1.357	--	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	regulation of multicellular organismal development	1	1.268	--	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	positive regulation of cellular catabolic process	0.04381	2.398	--	INHERITED FROM: positive regulation of autophagy
Biological Process (BP)	positive regulation of catabolic process	0.112	2.398	--	INHERITED FROM: positive regulation of autophagy
Biological Process (BP)	regulation of catabolic process	0.9249	1.553	--	INHERITED FROM: regulation of autophagy || positive regulation of autophagy
Biological Process (BP)	defense response to fungus	0.5535	2.222	--	INHERITED FROM: defense response to fungus, incompatible interaction
Biological Process (BP)	reproductive structure development	0.1541	1.658	--	INHERITED FROM: male gonad development || gonad development
Biological Process (BP)	sex differentiation	0.003122	1.796	--	INHERITED FROM: gonad development || development of primary male sexual characteristics || male gonad development || male sex differentiation
Biological Process (BP)	development of primary sexual characteristics	0.00131	1.921	--	INHERITED FROM: gonad development || development of primary male sexual characteristics || male gonad development
Biological Process (BP)	regulation of humoral immune response	0.3187	2.398	--	INHERITED FROM: regulation of antimicrobial humoral response || regulation of antifungal peptide production || positive regulation of antifungal peptide biosynthetic process || positive regulation of antimicrobial peptide biosynthetic process || regulation of antifungal peptide biosynthetic process || regulation of antimicrobial peptide biosynthetic process
Biological Process (BP)	leukocyte activation	0.3329	1.553	--	INHERITED FROM: macrophage activation involved in immune response || leukocyte activation involved in immune response || myeloid leukocyte activation || microglial cell activation involved in immune response || macrophage activation
Biological Process (BP)	cell activation involved in immune response	0.002801	2	--	INHERITED FROM: macrophage activation involved in immune response || microglial cell activation involved in immune response || leukocyte activation involved in immune response
Biological Process (BP)	myeloid cell activation involved in immune response	0.005408	2.222	--	INHERITED FROM: macrophage activation involved in immune response || microglial cell activation involved in immune response
Biological Process (BP)	immune response-activating signal transduction	0.004306	2.097	--	INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || innate immune response-activating signal transduction
Biological Process (BP)	immune response-regulating cell surface receptor signaling pathway	0.8131	2.222	--	INHERITED FROM: innate immune response activating cell surface receptor signaling pathway
Biological Process (BP)	immune response-activating cell surface receptor signaling pathway	1	2.222	--	INHERITED FROM: innate immune response activating cell surface receptor signaling pathway
Biological Process (BP)	behavior	1	1.357	--	INHERITED FROM: inter-male aggressive behavior || aggressive behavior
Biological Process (BP)	regulation of protein kinase activity	0.5149	1.62	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity || regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of protein phosphorylation	0.001326	1.745	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of phosphorylation	0.001699	1.745	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of protein modification process	0.004617	1.585	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of kinase activity	0.01897	1.854	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of protein kinase activity	0.03175	1.854	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of cellular protein metabolic process	0.9364	1.585	--	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	regulation of cellular protein metabolic process	0.8741	1.252	--	INHERITED FROM: activation of MAPK activity || regulation of protein serine/threonine kinase activity || positive regulation of protein serine/threonine kinase activity || regulation of protein modification process
Biological Process (BP)	regulation of catalytic activity	1	1.155	--	INHERITED FROM: activation of MAPK activity || positive regulation of transferase activity || regulation of protein serine/threonine kinase activity || positive regulation of protein serine/threonine kinase activity || regulation of transferase activity
Biological Process (BP)	regulation of phosphate metabolic process	0.00604	1.284	--	INHERITED FROM: activation of MAPK activity || regulation of phosphorylation || regulation of protein serine/threonine kinase activity || positive regulation of phosphate metabolic process || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	regulation of phosphorus metabolic process	1	1.252	--	INHERITED FROM: activation of MAPK activity || regulation of phosphorylation || regulation of protein serine/threonine kinase activity || positive regulation of phosphate metabolic process || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	macromolecule metabolic process	1	0.4634	--	INHERITED FROM: activation of MAPK activity || cytokine metabolic process || I-kappaB phosphorylation || cytokine biosynthetic process
Biological Process (BP)	primary metabolic process	1	0.2976	--	INHERITED FROM: activation of MAPK activity || cytokine metabolic process || I-kappaB phosphorylation || cytokine biosynthetic process
Biological Process (BP)	positive regulation of signaling	0.002561	1.377	--	INHERITED FROM: activation of MAPK activity || positive regulation of stress-activated MAPK cascade || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of JNK cascade || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of toll-like receptor signaling pathway || positive regulation of intracellular protein kinase cascade
Biological Process (BP)	regulation of MAPK cascade	0.8392	1.699	--	INHERITED FROM: activation of MAPK activity || positive regulation of stress-activated MAPK cascade || regulation of JNK cascade || positive regulation of JNK cascade || regulation of stress-activated MAPK cascade
Biological Process (BP)	regulation of signal transduction	1	1.119	--	INHERITED FROM: activation of MAPK activity || positive regulation of stress-activated MAPK cascade || regulation of toll-like receptor signaling pathway || regulation of intracellular protein kinase cascade || regulation of stress-activated MAPK cascade || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of JNK cascade || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of toll-like receptor signaling pathway || positive regulation of intracellular protein kinase cascade || regulation of JNK cascade || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	phosphorylation	0.04016	1.398	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	phosphorus metabolic process	0.9587	0.8013	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	protein modification process	0.9662	0.9066	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	macromolecule modification	1	0.8416	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	cellular protein metabolic process	1	0.6778	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	cellular metabolic process	1	0.2708	--	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	positive regulation of MAP kinase activity	0.6313	2.222	--	INHERITED FROM: activation of MAPK activity
Biological Process (BP)	single-organism cellular process	0	0.3915	Least Informative	DIRECT
Biological Process (BP)	response to stimulus	0	0.5498	Least Informative	DIRECT
Biological Process (BP)	regulation of cellular process	0.01046	0.5317	Least Informative	INHERITED FROM: positive regulation of cell motility || Toll signaling pathway || regulation of dendrite morphogenesis || positive regulation of cytokine secretion || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || immune response-regulating signaling pathway || regulation of interferon-alpha biosynthetic process || positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || regulation of nucleocytoplasmic transport || positive regulation of cellular biosynthetic process || toll-like receptor signaling pathway || regulation of cellular response to stress || positive regulation of interferon-alpha biosynthetic process || positive regulation of lymphocyte proliferation || regulation of nitric oxide biosynthetic process || positive regulation of cellular process || positive regulation of NF-kappaB transcription factor activity || regulation of phosphorylation || regulation of neuron projection development || cytokine-mediated signaling pathway || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of phosphate metabolic process || lipopolysaccharide-mediated signaling pathway || positive regulation of interferon-beta biosynthetic process || regulation of antifungal peptide biosynthetic process || I-kappaB kinase/NF-kappaB cascade || regulation of mononuclear cell proliferation || regulation of cytokine biosynthetic process || positive regulation of cell communication || positive regulation of mononuclear cell proliferation || regulation of leukocyte proliferation || positive regulation of toll-like receptor signaling pathway || regulation of transcription factor import into nucleus || positive regulation of cellular amide metabolic process || regulation of chemokine biosynthetic process || positive regulation of autophagy || regulation of toll-like receptor signaling pathway || regulation of interferon-beta biosynthetic process || regulation of stress-activated MAPK cascade || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || regulation of interferon-gamma biosynthetic process || positive regulation of cell migration || positive regulation of nitric oxide biosynthetic process || activation of MAPK activity || positive regulation of stress-activated MAPK cascade || signal transduction || positive regulation of leukocyte proliferation || regulation of autophagy || positive regulation of antimicrobial peptide biosynthetic process || regulation of protein modification process || I-kappaB phosphorylation || intracellular protein kinase cascade || regulation of cellular amide metabolic process || pattern recognition receptor signaling pathway || regulation of cell activation || positive regulation of NF-kappaB import into nucleus || positive regulation of cytokine biosynthetic process || positive regulation of protein import into nucleus || regulation of antimicrobial peptide biosynthetic process || positive regulation of JNK cascade || regulation of protein import into nucleus || positive regulation of I-kappaB kinase/NF-kappaB cascade || innate immune response activating cell surface receptor signaling pathway || positive regulation of intracellular protein kinase cascade || regulation of JNK cascade || regulation of intracellular protein kinase cascade || positive regulation of antifungal peptide biosynthetic process || positive regulation of protein serine/threonine kinase activity || positive regulation of interferon-gamma biosynthetic process || regulation of cell projection organization || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of cell activation || innate immune response-activating signal transduction || positive regulation of cellular metabolic process
Biological Process (BP)	regulation of metabolic process	0.6495	0.6946	Least Informative	INHERITED FROM: regulation of nitric-oxide synthase biosynthetic process || regulation of interferon-beta biosynthetic process || positive regulation of protein metabolic process || regulation of interferon-gamma biosynthetic process || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || regulation of interferon-alpha biosynthetic process || positive regulation of nitric-oxide synthase biosynthetic process || activation of MAPK activity || positive regulation of macromolecule metabolic process || positive regulation of cellular biosynthetic process || positive regulation of biosynthetic process || regulation of autophagy || regulation of transferase activity || positive regulation of antimicrobial peptide biosynthetic process || regulation of protein modification process || positive regulation of interferon-alpha biosynthetic process || regulation of nitric oxide biosynthetic process || regulation of cellular amide metabolic process || positive regulation of macromolecule biosynthetic process || regulation of biosynthetic process || positive regulation of NF-kappaB transcription factor activity || regulation of phosphorylation || regulation of sequence-specific DNA binding transcription factor activity || regulation of protein metabolic process || positive regulation of cytokine biosynthetic process || positive regulation of phosphate metabolic process || regulation of antimicrobial peptide biosynthetic process || positive regulation of interferon-beta biosynthetic process || regulation of antifungal peptide biosynthetic process || positive regulation of transferase activity || regulation of cytokine biosynthetic process || positive regulation of antifungal peptide biosynthetic process || positive regulation of protein serine/threonine kinase activity || positive regulation of interferon-gamma biosynthetic process || positive regulation of cellular amide metabolic process || positive regulation of metabolic process || regulation of chemokine biosynthetic process || positive regulation of cellular metabolic process || positive regulation of autophagy
Biological Process (BP)	developmental process	1	0.6904	Least Informative	INHERITED FROM: regulation of dendrite morphogenesis || development of primary male sexual characteristics || regulation of neuron projection development || male sex differentiation || gonad development || male gonad development || myeloid cell differentiation
Biological Process (BP)	multicellular organismal process	0.2608	0.6091	Least Informative	INHERITED FROM: regulation of dendrite morphogenesis || cytokine production || development of primary male sexual characteristics || regulation of neuron projection development || cytokine biosynthetic process || male sex differentiation || gonad development || male gonad development || type I interferon production || myeloid cell differentiation
Biological Process (BP)	protein metabolic process	0.7624	0.6383	Least Informative	INHERITED FROM: cytokine biosynthetic process || activation of MAPK activity || cytokine metabolic process || I-kappaB phosphorylation
Biological Process (BP)	cellular macromolecule metabolic process	1	0.4976	Least Informative	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	signal transduction	0	0.9914	Moderately Informative	DIRECT
Biological Process (BP)	regulation of protein metabolic process	0	1.119	Moderately Informative	DIRECT
Biological Process (BP)	immune system process	0	1.076	Moderately Informative	DIRECT
Biological Process (BP)	multi-organism process	0	1.086	Moderately Informative	DIRECT
Biological Process (BP)	regulation of response to stimulus	0	0.9914	Moderately Informative	DIRECT
Biological Process (BP)	response to organic substance	1.53e-14	1.018	Moderately Informative	DIRECT
Biological Process (BP)	regulation of multicellular organismal process	1.434e-12	0.9666	Moderately Informative	DIRECT
Biological Process (BP)	positive regulation of metabolic process	2.757e-08	1.167	Moderately Informative	DIRECT
Biological Process (BP)	response to oxygen-containing compound	6.689e-07	1.108	Moderately Informative	DIRECT
Biological Process (BP)	positive regulation of cellular process	6.862e-05	0.9066	Moderately Informative	DIRECT
Biological Process (BP)	regulation of biosynthetic process	0.0003684	0.9914	Moderately Informative	DIRECT
Biological Process (BP)	response to abiotic stimulus	1	1.108	Moderately Informative	INHERITED FROM: cellular response to mechanical stimulus || response to mechanical stimulus
Biological Process (BP)	regulation of localization	0.4873	1.066	Moderately Informative	INHERITED FROM: regulation of protein transport || positive regulation of cell motility || positive regulation of protein import into nucleus || regulation of protein import into nucleus || positive regulation of cytokine secretion || positive regulation of cell migration || positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || regulation of nucleocytoplasmic transport || regulation of establishment of protein localization || positive regulation of protein transport || regulation of transcription factor import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of gene expression	1	0.9914	Moderately Informative	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	regulation of nitrogen compound metabolic process	1	0.9914	Moderately Informative	INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || regulation of antimicrobial peptide biosynthetic process || regulation of antifungal peptide biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || positive regulation of antifungal peptide biosynthetic process || positive regulation of antimicrobial peptide biosynthetic process || regulation of nitric oxide biosynthetic process || regulation of cellular amide metabolic process || positive regulation of cellular amide metabolic process || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	reproduction	1	1.097	Moderately Informative	INHERITED FROM: development of primary male sexual characteristics || gonad development || male sex differentiation || male gonad development
Biological Process (BP)	regulation of cellular metabolic process	0.1408	0.7905	Moderately Informative	INHERITED FROM: regulation of interferon-beta biosynthetic process || regulation of interferon-gamma biosynthetic process || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || regulation of interferon-alpha biosynthetic process || activation of MAPK activity || positive regulation of cellular biosynthetic process || regulation of autophagy || positive regulation of antimicrobial peptide biosynthetic process || regulation of protein modification process || positive regulation of interferon-alpha biosynthetic process || regulation of nitric oxide biosynthetic process || regulation of cellular amide metabolic process || positive regulation of NF-kappaB transcription factor activity || regulation of phosphorylation || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of cytokine biosynthetic process || positive regulation of phosphate metabolic process || regulation of antimicrobial peptide biosynthetic process || positive regulation of interferon-beta biosynthetic process || regulation of antifungal peptide biosynthetic process || regulation of cytokine biosynthetic process || positive regulation of antifungal peptide biosynthetic process || positive regulation of protein serine/threonine kinase activity || positive regulation of interferon-gamma biosynthetic process || positive regulation of cellular amide metabolic process || regulation of chemokine biosynthetic process || positive regulation of cellular metabolic process || positive regulation of autophagy
Biological Process (BP)	regulation of signaling	0.0191	1.076	Moderately Informative	INHERITED FROM: regulation of toll-like receptor signaling pathway || regulation of stress-activated MAPK cascade || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || positive regulation of JNK cascade || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of intracellular protein kinase cascade || regulation of JNK cascade || activation of MAPK activity || positive regulation of stress-activated MAPK cascade || regulation of intracellular protein kinase cascade || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of toll-like receptor signaling pathway || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of cell communication	0.047	1.066	Moderately Informative	INHERITED FROM: regulation of toll-like receptor signaling pathway || regulation of stress-activated MAPK cascade || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || positive regulation of JNK cascade || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of intracellular protein kinase cascade || regulation of JNK cascade || activation of MAPK activity || positive regulation of stress-activated MAPK cascade || regulation of intracellular protein kinase cascade || positive regulation of cell communication || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of toll-like receptor signaling pathway || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	response to endogenous stimulus	1	1.237	Moderately Informative	INHERITED FROM: response to peptidoglycan
Biological Process (BP)	cellular response to chemical stimulus	0.002536	1.097	Moderately Informative	INHERITED FROM: cytokine-mediated signaling pathway || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound || cellular response to lipopolysaccharide || cellular response to lipoteichoic acid
Biological Process (BP)	regulation of cellular component organization	1	1.18	Moderately Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis || regulation of cell projection organization
Biological Process (BP)	cell differentiation	0.4705	1.009	Moderately Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis || myeloid cell differentiation
Biological Process (BP)	nervous system development	0.4499	1.194	Moderately Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	regulation of developmental process	1	1.155	Moderately Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	organ development	1	0.9355	Moderately Informative	INHERITED FROM: gonad development || male gonad development || myeloid cell differentiation
Biological Process (BP)	single-organism developmental process	1	0.7645	Moderately Informative	INHERITED FROM: gonad development || male gonad development || myeloid cell differentiation
Biological Process (BP)	regulation of molecular function	0.07051	1.056	Moderately Informative	INHERITED FROM: activation of MAPK activity || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of protein serine/threonine kinase activity || regulation of transferase activity || positive regulation of transferase activity || regulation of protein serine/threonine kinase activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of NF-kappaB transcription factor activity
Biological Process (BP)	phosphate-containing compound metabolic process	0.918	0.8182	Moderately Informative	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	cellular protein modification process	0.9662	0.9066	Moderately Informative	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	immune response	0	1.495	Informative	DIRECT
Biological Process (BP)	regulation of cytokine production	0	1.62	Informative	DIRECT
Biological Process (BP)	positive regulation of immune system process	0	1.62	Informative	DIRECT
Biological Process (BP)	positive regulation of protein metabolic process	0	1.469	Informative	DIRECT
Biological Process (BP)	regulation of response to stress	0	1.42	Informative	DIRECT
Biological Process (BP)	regulation of immune response	0	1.553	Informative	DIRECT
Biological Process (BP)	defense response	0	1.357	Informative	DIRECT
Biological Process (BP)	response to other organism	0	1.398	Informative	DIRECT
Biological Process (BP)	cell activation	2.548e-13	1.495	Informative	DIRECT
Biological Process (BP)	positive regulation of cellular biosynthetic process	4.626e-11	1.495	Informative	DIRECT
Biological Process (BP)	positive regulation of multicellular organismal process	1.157e-10	1.585	Informative	DIRECT
Biological Process (BP)	regulation of intracellular protein kinase cascade	5.232e-09	1.469	Informative	DIRECT
Biological Process (BP)	positive regulation of macromolecule biosynthetic process	8.172e-09	1.585	Informative	DIRECT
Biological Process (BP)	cellular response to oxygen-containing compound	8.487e-06	1.319	Informative	DIRECT
Biological Process (BP)	response to external stimulus	1	1.319	Informative	INHERITED FROM: cellular response to mechanical stimulus || response to mechanical stimulus
Biological Process (BP)	regulation of cell proliferation	0.7033	1.42	Informative	INHERITED FROM: positive regulation of leukocyte proliferation || positive regulation of mononuclear cell proliferation || regulation of leukocyte proliferation || regulation of mononuclear cell proliferation || positive regulation of lymphocyte proliferation
Biological Process (BP)	regulation of protein localization	0.001223	1.585	Informative	INHERITED FROM: regulation of protein transport || regulation of establishment of protein localization || positive regulation of transcription factor import into nucleus || regulation of protein import into nucleus || positive regulation of protein transport || positive regulation of protein import into nucleus || positive regulation of cytokine secretion || regulation of transcription factor import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of secretion	0.194	1.658	Informative	INHERITED FROM: positive regulation of cytokine secretion
Biological Process (BP)	regulation of anatomical structure morphogenesis	0.6542	1.42	Informative	INHERITED FROM: regulation of dendrite morphogenesis
Biological Process (BP)	positive regulation of transport	0.4025	1.495	Informative	INHERITED FROM: positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || positive regulation of cytokine secretion || positive regulation of protein transport || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of intracellular transport	0.06019	1.585	Informative	INHERITED FROM: positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || regulation of protein import into nucleus || regulation of nucleocytoplasmic transport || positive regulation of protein import into nucleus || regulation of transcription factor import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	developmental process involved in reproduction	0.4993	1.469	Informative	INHERITED FROM: male sex differentiation || development of primary male sexual characteristics || male gonad development || gonad development
Biological Process (BP)	regulation of growth	0.06767	1.42	Informative	INHERITED FROM: regulation of growth of symbiont in host || negative regulation of growth of symbiont involved in interaction with host || negative regulation of growth of symbiont in host || modulation of growth of symbiont involved in interaction with host || negative regulation of growth
Biological Process (BP)	response to organic cyclic compound	1	1.523	Informative	INHERITED FROM: response to exogenous dsRNA
Biological Process (BP)	positive regulation of nitrogen compound metabolic process	0.8577	1.523	Informative	INHERITED FROM: positive regulation of cellular amide metabolic process || positive regulation of nitric oxide biosynthetic process || positive regulation of antifungal peptide biosynthetic process || positive regulation of antimicrobial peptide biosynthetic process
Biological Process (BP)	response to organic nitrogen	0.8394	1.495	Informative	INHERITED FROM: response to peptidoglycan
Biological Process (BP)	response to lipid	0.006083	1.658	Informative	INHERITED FROM: lipopolysaccharide-mediated signaling pathway || detection of lipopolysaccharide || response to lipopolysaccharide || cellular response to lipopolysaccharide
Biological Process (BP)	regulation of cellular component movement	0.647	1.699	Informative	INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility
Biological Process (BP)	regulation of locomotion	0.7096	1.745	Informative	INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility
Biological Process (BP)	hematopoietic or lymphoid organ development	0.005818	1.585	Informative	INHERITED FROM: myeloid cell differentiation
Biological Process (BP)	response to cytokine stimulus	0.06815	1.658	Informative	INHERITED FROM: cytokine-mediated signaling pathway
Biological Process (BP)	regulation of nervous system development	0.00509	1.658	Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	regulation of cell development	0.01126	1.469	Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	generation of neurons	0.08016	1.469	Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	regulation of cellular catabolic process	0.9247	1.553	Informative	INHERITED FROM: regulation of autophagy || positive regulation of autophagy
Biological Process (BP)	reproductive system development	0.1541	1.658	Informative	INHERITED FROM: male gonad development || gonad development
Biological Process (BP)	intracellular signal transduction	1	1.398	Informative	INHERITED FROM: I-kappaB phosphorylation || intracellular protein kinase cascade || I-kappaB kinase/NF-kappaB cascade
Biological Process (BP)	regulation of immune effector process	0.902	1.658	Informative	INHERITED FROM: regulation of antifungal peptide production || regulation of antifungal peptide biosynthetic process || regulation of production of molecular mediator of immune response || positive regulation of myeloid leukocyte cytokine production involved in immune response || regulation of macrophage cytokine production || positive regulation of production of molecular mediator of immune response || positive regulation of antifungal peptide biosynthetic process || positive regulation of macrophage cytokine production || positive regulation of antimicrobial peptide biosynthetic process || regulation of antimicrobial peptide biosynthetic process
Biological Process (BP)	immune effector process	0.01294	1.658	Informative	INHERITED FROM: macrophage activation involved in immune response || immunoglobulin mediated immune response || leukocyte activation involved in immune response || lymphocyte mediated immunity || microglial cell activation involved in immune response
Biological Process (BP)	regulation of kinase activity	0.2412	1.62	Informative	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity || regulation of protein serine/threonine kinase activity
Biological Process (BP)	regulation of protein phosphorylation	0.3967	1.495	Informative	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity || regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of catalytic activity	1	1.337	Informative	INHERITED FROM: activation of MAPK activity || positive regulation of protein serine/threonine kinase activity || positive regulation of transferase activity
Biological Process (BP)	positive regulation of phosphorus metabolic process	0.7357	1.658	Informative	INHERITED FROM: activation of MAPK activity || positive regulation of phosphate metabolic process || positive regulation of protein serine/threonine kinase activity
Biological Process (BP)	positive regulation of signal transduction	0.3278	1.377	Informative	INHERITED FROM: activation of MAPK activity || positive regulation of stress-activated MAPK cascade || positive regulation of stress-activated protein kinase signaling cascade || positive regulation of JNK cascade || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of toll-like receptor signaling pathway || positive regulation of intracellular protein kinase cascade
Biological Process (BP)	protein phosphorylation	0.0146	1.585	Informative	INHERITED FROM: activation of MAPK activity || I-kappaB phosphorylation
Biological Process (BP)	regulation of cytokine biosynthetic process	0	2.222	Highly Informative	DIRECT
Biological Process (BP)	activation of immune response	0	1.921	Highly Informative	DIRECT
Biological Process (BP)	regulation of innate immune response	0	2.097	Highly Informative	DIRECT
Biological Process (BP)	immune response-regulating signaling pathway	0	2	Highly Informative	DIRECT
Biological Process (BP)	myeloid leukocyte activation	4.008e-15	2	Highly Informative	DIRECT
Biological Process (BP)	regulation of multi-organism process	7.835e-15	2.097	Highly Informative	DIRECT
Biological Process (BP)	response to lipopolysaccharide	7.835e-15	2.222	Highly Informative	DIRECT
Biological Process (BP)	cellular response to biotic stimulus	3.329e-14	2.097	Highly Informative	DIRECT
Biological Process (BP)	symbiosis, encompassing mutualism through parasitism	4.382e-14	1.854	Highly Informative	DIRECT
Biological Process (BP)	regulation of mononuclear cell proliferation	2.313e-11	2.222	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of protein transport	3.688e-11	2.097	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of leukocyte proliferation	7.769e-11	2.222	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of cytokine production	2.948e-10	1.921	Highly Informative	DIRECT
Biological Process (BP)	modification of morphology or physiology of other organism	2.164e-08	2.097	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of sequence-specific DNA binding transcription factor activity	5.894e-08	2.097	Highly Informative	DIRECT
Biological Process (BP)	regulation of nitric oxide biosynthetic process	8.205e-08	2.222	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of protein serine/threonine kinase activity	8.642e-08	2.097	Highly Informative	DIRECT
Biological Process (BP)	regulation of cellular response to stress	1.911e-06	1.921	Highly Informative	DIRECT
Biological Process (BP)	regulation of nucleocytoplasmic transport	3.417e-06	2	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of cell activation	1.363e-05	2	Highly Informative	DIRECT
Biological Process (BP)	leukocyte activation involved in immune response	4.105e-05	2	Highly Informative	DIRECT
Biological Process (BP)	cytokine-mediated signaling pathway	8.53e-05	1.921	Highly Informative	DIRECT
Biological Process (BP)	gonad development	0.0004231	2	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of cell migration	0.0004377	1.921	Highly Informative	DIRECT
Biological Process (BP)	regulation of cell projection organization	0.0009438	2.097	Highly Informative	DIRECT
Biological Process (BP)	cellular response to abiotic stimulus	0.1108	2.097	Highly Informative	INHERITED FROM: cellular response to mechanical stimulus
Biological Process (BP)	regulation of protein secretion	0.1385	2	Highly Informative	INHERITED FROM: positive regulation of cytokine secretion
Biological Process (BP)	positive regulation of secretion	0.4662	2	Highly Informative	INHERITED FROM: positive regulation of cytokine secretion
Biological Process (BP)	regulation of lymphocyte activation	0.3761	2	Highly Informative	INHERITED FROM: positive regulation of lymphocyte proliferation
Biological Process (BP)	regulation of cell morphogenesis	0.05752	1.854	Highly Informative	INHERITED FROM: regulation of dendrite morphogenesis
Biological Process (BP)	positive regulation of intracellular transport	0.001034	2	Highly Informative	INHERITED FROM: positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of protein localization to nucleus	0.003526	2.097	Highly Informative	INHERITED FROM: regulation of transcription factor import into nucleus || positive regulation of transcription factor import into nucleus || regulation of protein import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	regulation of intracellular protein transport	0.1177	1.921	Highly Informative	INHERITED FROM: regulation of transcription factor import into nucleus || positive regulation of transcription factor import into nucleus || regulation of protein import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus
Biological Process (BP)	negative regulation of multicellular organismal process	0.08664	1.854	Highly Informative	INHERITED FROM: negative regulation of interleukin-17 production
Biological Process (BP)	leukocyte mediated immunity	1	1.921	Highly Informative	INHERITED FROM: immunoglobulin mediated immune response || lymphocyte mediated immunity
Biological Process (BP)	regulation of neuron differentiation	0.6223	1.854	Highly Informative	INHERITED FROM: regulation of neuron projection development || regulation of dendrite morphogenesis
Biological Process (BP)	response to fungus	0.138	2	Highly Informative	INHERITED FROM: defense response to fungus, incompatible interaction || response to molecule of fungal origin
Biological Process (BP)	innate immune response	0.03711	1.921	Highly Informative	INHERITED FROM: defense response to fungus, incompatible interaction
Biological Process (BP)	positive regulation of immune effector process	1	1.921	Highly Informative	INHERITED FROM: positive regulation of production of molecular mediator of immune response || positive regulation of myeloid leukocyte cytokine production involved in immune response || positive regulation of macrophage cytokine production
Biological Process (BP)	multi-organism behavior	0.7037	2.222	Highly Informative	INHERITED FROM: inter-male aggressive behavior || aggressive behavior
Biological Process (BP)	positive regulation of MAPK cascade	0.007701	1.854	Highly Informative	INHERITED FROM: activation of MAPK activity || positive regulation of stress-activated MAPK cascade || positive regulation of JNK cascade
Biological Process (BP)	activation of protein kinase activity	0.01423	2	Highly Informative	INHERITED FROM: activation of MAPK activity
Biological Process (BP)	regulation of MAP kinase activity	0.8503	2.097	Highly Informative	INHERITED FROM: activation of MAPK activity
Molecular Function (MF)	signal transducer activity	0	1.599	--	DIRECT
Molecular Function (MF)	amide binding	1.762e-11	1.775	--	DIRECT
Molecular Function (MF)	cytokine receptor activity	1.137e-10	2.377	--	DIRECT
Molecular Function (MF)	double-stranded RNA binding	6.023e-10	2.377	--	DIRECT
Molecular Function (MF)	growth factor binding	0.0002277	2.679	--	DIRECT
Molecular Function (MF)	transmembrane signaling receptor activity	1	1.724	--	INHERITED FROM: cytokine receptor activity || interleukin-1 receptor activity
Molecular Function (MF)	nucleic acid binding	0.00112	1.11	--	INHERITED FROM: single-stranded RNA binding || siRNA binding || RNA binding || double-stranded RNA binding
Molecular Function (MF)	molecular_function	1	0	--	INHERITED FROM: lipopolysaccharide receptor activity || peptide binding || cytokine receptor activity || receptor activity || RNA binding || signal transducer activity || pattern recognition receptor activity || interleukin-1 receptor activity || molecular transducer activity || amide binding || protein heterodimerization activity || lipopeptide binding || lipid binding || interleukin-1 binding || cytokine binding || double-stranded RNA binding || growth factor binding || siRNA binding || binding || single-stranded RNA binding
Molecular Function (MF)	signaling receptor activity	0.2772	1.724	--	INHERITED FROM: lipopolysaccharide receptor activity || pattern recognition receptor activity || cytokine receptor activity || interleukin-1 receptor activity
Molecular Function (MF)	binding	2.181e-08	0.3952	Least Informative	DIRECT
Molecular Function (MF)	protein binding	1	0.77	Moderately Informative	INHERITED FROM: interleukin-1 binding || growth factor binding || cytokine binding || protein heterodimerization activity
Molecular Function (MF)	heterocyclic compound binding	0.2634	0.8932	Moderately Informative	INHERITED FROM: single-stranded RNA binding || siRNA binding || RNA binding || double-stranded RNA binding
Molecular Function (MF)	organic cyclic compound binding	0.3044	0.846	Moderately Informative	INHERITED FROM: single-stranded RNA binding || siRNA binding || RNA binding || double-stranded RNA binding
Molecular Function (MF)	molecular transducer activity	0	1.565	Informative	DIRECT
Molecular Function (MF)	receptor activity	0	1.637	Informative	DIRECT
Molecular Function (MF)	lipid binding	1.641e-10	1.377	Informative	DIRECT
Molecular Function (MF)	RNA binding	2.625e-09	1.4	Informative	DIRECT
Molecular Function (MF)	protein dimerization activity	0.0115	1.637	Informative	INHERITED FROM: protein heterodimerization activity
Molecular Function (MF)	peptide binding	7.49e-15	1.833	Highly Informative	DIRECT
Molecular Function (MF)	protein heterodimerization activity	1.936e-06	2.076	Highly Informative	DIRECT
Cellular Component (CC)	endosome membrane	7.282e-09	2.241	--	DIRECT
Cellular Component (CC)	membrane part	2.002e-08	0.6842	--	DIRECT
Cellular Component (CC)	cell periphery	1.878e-07	0.8256	--	DIRECT
Cellular Component (CC)	plasma membrane part	7.061e-05	1.036	--	DIRECT
Cellular Component (CC)	organelle part	1	0.3713	--	INHERITED FROM: endosomal part || endosome membrane
Cellular Component (CC)	cytoplasm	0.9338	0.2515	--	INHERITED FROM: endosomal part || lysosome || endosome || endocytic vesicle || early phagosome || vacuole || endosome membrane
Cellular Component (CC)	macromolecular complex	0.1463	0.4276	--	INHERITED FROM: Toll-like receptor 2-Toll-like receptor 6 protein complex || lipopolysaccharide receptor complex || receptor complex
Cellular Component (CC)	cytoplasmic membrane-bounded vesicle	0.00105	1.241	--	INHERITED FROM: endocytic vesicle || early phagosome
Cellular Component (CC)	membrane-bounded vesicle	0.001744	1.219	--	INHERITED FROM: endocytic vesicle || early phagosome
Cellular Component (CC)	cytoplasmic vesicle	0.002766	1.18	--	INHERITED FROM: endocytic vesicle || early phagosome
Cellular Component (CC)	cell part	0.699	0.08068	--	INHERITED FROM: lysosome || plasma membrane || endosome || vacuole || endosomal part || early phagosome || Toll-like receptor 2-Toll-like receptor 6 protein complex || cell periphery || plasma membrane part || endocytic vesicle || endosome membrane || cell surface
Cellular Component (CC)	cell	0.7013	0.08068	--	INHERITED FROM: lysosome || plasma membrane || endosome || vacuole || endosomal part || early phagosome || Toll-like receptor 2-Toll-like receptor 6 protein complex || cell periphery || plasma membrane part || endocytic vesicle || endosome membrane || cell surface
Cellular Component (CC)	cellular_component	1	0	--	INHERITED FROM: lysosome || plasma membrane || endosome || vacuole || integral to membrane || receptor complex || endosomal part || early phagosome || Toll-like receptor 2-Toll-like receptor 6 protein complex || cell periphery || lipopolysaccharide receptor complex || membrane part || plasma membrane part || membrane || endocytic vesicle || endosome membrane || cell surface
Cellular Component (CC)	intracellular part	1	0.1266	--	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	membrane-bounded organelle	1	0.2912	--	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	intracellular	1	0.1266	--	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	organelle	1	0.1836	--	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	intracellular organelle	1	0.1875	--	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	lytic vacuole	0.01556	1.696	--	INHERITED FROM: lysosome
Cellular Component (CC)	membrane	1.494e-14	0.5731	Least Informative	DIRECT
Cellular Component (CC)	intracellular organelle part	1	0.3893	Least Informative	INHERITED FROM: endosomal part || endosome membrane
Cellular Component (CC)	cytoplasmic part	0.9606	0.2605	Least Informative	INHERITED FROM: endosomal part || lysosome || endosome || endocytic vesicle || early phagosome || vacuole || endosome membrane
Cellular Component (CC)	protein complex	0.01761	0.5639	Least Informative	INHERITED FROM: Toll-like receptor 2-Toll-like receptor 6 protein complex || lipopolysaccharide receptor complex || receptor complex
Cellular Component (CC)	intracellular membrane-bounded organelle	1	0.2961	Least Informative	INHERITED FROM: lysosome || endosome || vacuole || endosomal part || endocytic vesicle || early phagosome || endosome membrane
Cellular Component (CC)	plasma membrane	1.451e-08	0.9734	Moderately Informative	DIRECT
Cellular Component (CC)	vesicle	0.005417	1.144	Moderately Informative	INHERITED FROM: endocytic vesicle || early phagosome
Cellular Component (CC)	intrinsic to membrane	0.6751	1.18	Moderately Informative	INHERITED FROM: integral to membrane || lipopolysaccharide receptor complex
Cellular Component (CC)	organelle membrane	0.03321	0.8514	Moderately Informative	INHERITED FROM: endosome membrane
Cellular Component (CC)	endosome	1.817e-11	1.462	Informative	DIRECT
Cellular Component (CC)	cell surface	9.71e-11	1.542	Informative	DIRECT
Cellular Component (CC)	integral to membrane	1.988e-05	1.286	Informative	DIRECT
Cellular Component (CC)	vacuole	4.213e-05	1.337	Informative	DIRECT
Cellular Component (CC)	receptor complex	0	2.064	Highly Informative	DIRECT
Cellular Component (CC)	endosomal part	2.498e-11	2.064	Highly Informative	DIRECT
Cellular Component (CC)	endocytic vesicle	3.106e-08	2.064	Highly Informative	DIRECT
Cellular Component (CC)	lysosome	3.479e-07	1.94	Highly Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	DO term	FDR (all)	IC level	SDDO level	Annotation (direct or inherited)
Disease Ontology (DO)	systemic mycosis	1.08e-09	1.855	--	DIRECT
Disease Ontology (DO)	respiratory system disease	8.919e-08	0.8853	--	DIRECT
Disease Ontology (DO)	fungal infectious disease	8.712e-05	1.855	--	DIRECT
Disease Ontology (DO)	nasal cavity disease	0.0001207	1.429	--	DIRECT
Disease Ontology (DO)	nose disease	0.0001582	1.429	--	DIRECT
Disease Ontology (DO)	disease of anatomical entity	0.0002866	0.2119	--	DIRECT
Disease Ontology (DO)	hypersensitivity reaction disease	0.0003055	0.8139	--	DIRECT
Disease Ontology (DO)	bone inflammation disease	0.0004495	1.186	--	DIRECT
Disease Ontology (DO)	parasitic infectious disease	0.00399	1.332	--	INHERITED FROM: filariasis || malaria
Disease Ontology (DO)	bronchial disease	0.004495	1.332	--	INHERITED FROM: asthma
Disease Ontology (DO)	musculoskeletal system disease	0.0117	0.8273	--	INHERITED FROM: myositis || bone inflammation disease
Disease Ontology (DO)	obstructive lung disease	0.06044	1.156	--	INHERITED FROM: asthma
Disease Ontology (DO)	hepatobiliary disease	0.1671	1.429	--	INHERITED FROM: liver disease
Disease Ontology (DO)	upper respiratory tract disease	0.2077	1.378	--	INHERITED FROM: nose disease || nasal cavity disease || allergic rhinitis
Disease Ontology (DO)	muscular disease	0.484	1.332	--	INHERITED FROM: myositis
Disease Ontology (DO)	parasitic protozoa infectious disease	0.5032	1.429	--	INHERITED FROM: malaria
Disease Ontology (DO)	lower respiratory tract disease	0.6502	0.9522	--	INHERITED FROM: asthma || lung disease
Disease Ontology (DO)	myopathy	1	1.332	--	INHERITED FROM: myositis
Disease Ontology (DO)	rhinitis	1	1.429	--	INHERITED FROM: allergic rhinitis
Disease Ontology (DO)	muscle tissue disease	1	1.332	--	INHERITED FROM: myositis
Disease Ontology (DO)	immune system disease	0.08183	0.6792	Least Informative	INHERITED FROM: hypersensitivity reaction disease || sarcoidosis
Disease Ontology (DO)	lung disease	1.209e-09	0.9707	Moderately Informative	DIRECT
Disease Ontology (DO)	disease by infectious agent	6.517e-07	0.8273	Moderately Informative	DIRECT
Disease Ontology (DO)	gastrointestinal system disease	0.01074	0.8139	Moderately Informative	INHERITED FROM: liver disease
Disease Ontology (DO)	bone disease	0.4221	1.128	Moderately Informative	INHERITED FROM: bone inflammation disease
Disease Ontology (DO)	asthma	1.66e-11	1.554	Informative	DIRECT
Disease Ontology (DO)	malaria	5.369e-06	1.554	Informative	DIRECT
Disease Ontology (DO)	allergic rhinitis	0.0001092	1.429	Informative	DIRECT
Disease Ontology (DO)	liver disease	0.0002166	1.429	Informative	DIRECT
Disease Ontology (DO)	parasitic helminthiasis infectious disease	0.02406	1.73	Informative	INHERITED FROM: filariasis
Disease Ontology (DO)	hypersensitivity reaction type IV disease	0.05185	1.73	Informative	INHERITED FROM: sarcoidosis
Disease Ontology (DO)	opportunistic mycosis	6.085e-10	1.855	Highly Informative	DIRECT
Disease Ontology (DO)	filariasis	1.46e-09	2.031	Highly Informative	DIRECT
Disease Ontology (DO)	myositis	0.0007893	2.031	Highly Informative	DIRECT
Disease Ontology (DO)	sarcoidosis	0.0008283	1.855	Highly Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	MP term	FDR (all)	IC level	SDMP level	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal cytokine secretion	0	1.261	--	DIRECT
Mammalian Phenotype (MP)	decreased immunoglobulin level	5.671e-10	1.766	--	DIRECT
Mammalian Phenotype (MP)	decreased tumor necrosis factor secretion	5.733e-10	2.164	--	DIRECT
Mammalian Phenotype (MP)	abnormal immune system physiology	1.795e-09	0.733	--	DIRECT
Mammalian Phenotype (MP)	abnormal intercellular signaling peptide or protein level	1.129e-07	1.465	--	DIRECT
Mammalian Phenotype (MP)	decreased macrophage cytokine production	1.818e-07	2.465	--	DIRECT
Mammalian Phenotype (MP)	decreased circulating interleukin-6 level	3.595e-07	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal retinal progenitor cell morphology	6.583e-07	2.465	--	DIRECT
Mammalian Phenotype (MP)	decreased macrophage nitric oxide production	1.082e-06	2.465	--	DIRECT
Mammalian Phenotype (MP)	rectal hemorrhage	4.878e-06	2.465	--	DIRECT
Mammalian Phenotype (MP)	large intestinal inflammation	8.11e-06	1.766	--	DIRECT
Mammalian Phenotype (MP)	abnormal circulating interferon-alpha level	8.422e-06	2.465	--	DIRECT
Mammalian Phenotype (MP)	decreased circulating alanine transaminase level	1.711e-05	2.164	--	DIRECT
Mammalian Phenotype (MP)	abnormal NK T cell physiology	1.86e-05	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal circulating protein level	4.856e-05	1.235	--	DIRECT
Mammalian Phenotype (MP)	increased mature B cell number	6.395e-05	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal interleukin-12b secretion	7.019e-05	1.988	--	DIRECT
Mammalian Phenotype (MP)	decreased interleukin-12 secretion	9.653e-05	2.465	--	DIRECT
Mammalian Phenotype (MP)	decreased susceptibility to endotoxin shock	0.0001139	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal intestine physiology	0.000177	1.687	--	DIRECT
Mammalian Phenotype (MP)	abnormal splenocyte proliferation	0.0001854	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal self tolerance	0.0001872	1.424	--	DIRECT
Mammalian Phenotype (MP)	decreased fat cell size	0.0002224	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal dendritic cell physiology	0.0002994	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal bronchial provocation	0.0003416	1.766	--	DIRECT
Mammalian Phenotype (MP)	decreased circulating tumor necrosis factor level	0.0003416	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal fat pad morphology	0.0004629	1.766	--	DIRECT
Mammalian Phenotype (MP)	altered susceptibility to kidney reperfusion injury	0.0004879	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal leukocyte morphology	0.0007415	0.8743	--	DIRECT
Mammalian Phenotype (MP)	abnormal macrophage cytokine production	0.0007456	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal immune system cell morphology	0.0007851	0.8633	--	DIRECT
Mammalian Phenotype (MP)	decreased susceptibility to induced joint inflammation	0.0009296	2.465	--	DIRECT
Mammalian Phenotype (MP)	abnormal NK cell physiology	0.001232	1.766	--	INHERITED FROM: impaired natural killer cell mediated cytotoxicity
Mammalian Phenotype (MP)	abnormal splenocyte physiology	0.00127	2.465	--	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal spleen physiology	0.001527	2.164	--	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal renal/urinary system physiology	0.003007	1.289	--	INHERITED FROM: altered susceptibility to kidney reperfusion injury || abnormal kidney physiology
Mammalian Phenotype (MP)	hematopoietic system phenotype	0.003056	0.7578	--	INHERITED FROM: abnormal lymphocyte morphology || abnormal leukocyte morphology || abnormal splenocyte proliferation || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal hematopoiesis	0.003286	0.8219	--	INHERITED FROM: abnormal lymphocyte morphology || abnormal leukocyte morphology || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal response to infection	0.003302	1.143	--	INHERITED FROM: increased susceptibility to infection || altered susceptibility to infection
Mammalian Phenotype (MP)	abnormal blood cell morphology/development	0.003541	0.8219	--	INHERITED FROM: abnormal lymphocyte morphology || abnormal leukocyte morphology || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal macrophage nitric oxide production	0.004103	2.465	--	INHERITED FROM: decreased macrophage nitric oxide production
Mammalian Phenotype (MP)	abnormal professional antigen presenting cell physiology	0.007294	1.289	--	INHERITED FROM: decreased macrophage cytokine production || decreased macrophage nitric oxide production || decreased immunoglobulin level || abnormal macrophage cytokine production || abnormal dendritic cell physiology
Mammalian Phenotype (MP)	increased B cell number	0.01174	2.465	--	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal blood homeostasis	0.01393	0.7494	--	INHERITED FROM: decreased circulating alanine transaminase level || abnormal circulating protein level || decreased circulating tumor necrosis factor level || decreased circulating interleukin-6 level || abnormal circulating interferon-alpha level
Mammalian Phenotype (MP)	intestinal inflammation	0.02292	1.766	--	INHERITED FROM: large intestinal inflammation || colitis
Mammalian Phenotype (MP)	abnormal adipose tissue morphology	0.02679	1.351	--	INHERITED FROM: decreased fat cell size || abnormal fat pad morphology
Mammalian Phenotype (MP)	abnormal eye development	0.02679	1.766	--	INHERITED FROM: abnormal retinal development || abnormal retinal progenitor cell morphology
Mammalian Phenotype (MP)	adipose tissue phenotype	0.02883	1.319	--	INHERITED FROM: decreased fat cell size || abnormal fat pad morphology
Mammalian Phenotype (MP)	abnormal B-1 B cell morphology	0.0291	1.863	--	INHERITED FROM: abnormal B-1 B cell number
Mammalian Phenotype (MP)	abnormal respiratory system physiology	0.03406	1.351	--	INHERITED FROM: abnormal bronchial provocation || abnormal airway responsiveness
Mammalian Phenotype (MP)	abnormal immune tolerance	0.07737	1.424	--	INHERITED FROM: autoimmune response || abnormal self tolerance
Mammalian Phenotype (MP)	abnormal mature B cell morphology	0.08042	1.766	--	INHERITED FROM: abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal respiratory function	0.08701	1.62	--	INHERITED FROM: abnormal airway responsiveness || abnormal bronchial provocation
Mammalian Phenotype (MP)	abnormal leukocyte cell number	0.1017	1.21	--	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal retina morphology	0.1276	1.289	--	INHERITED FROM: abnormal retinal development || abnormal retinal progenitor cell morphology
Mammalian Phenotype (MP)	abnormal immunoglobulin level	0.1337	1.687	--	INHERITED FROM: decreased immunoglobulin level
Mammalian Phenotype (MP)	abnormal ocular fundus morphology	0.1368	1.187	--	INHERITED FROM: abnormal retinal development || abnormal retinal progenitor cell morphology
Mammalian Phenotype (MP)	abnormal cytokine level	0.1368	1.465	--	INHERITED FROM: abnormal circulating interferon-alpha level || decreased circulating tumor necrosis factor level || decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	abnormal posterior eye segment morphology	0.175	1.187	--	INHERITED FROM: abnormal retinal development || abnormal retinal progenitor cell morphology
Mammalian Phenotype (MP)	homeostasis/metabolism phenotype	0.203	0.4162	--	INHERITED FROM: decreased circulating tumor necrosis factor level || abnormal circulating interferon-alpha level || abnormal protein level || decreased circulating alanine transaminase level || abnormal intercellular signaling peptide or protein level || abnormal vascular wound healing || abnormal circulating protein level || decreased macrophage nitric oxide production || decreased circulating interleukin-6 level || altered susceptibility to kidney reperfusion injury
Mammalian Phenotype (MP)	abnormal cell physiology	0.2214	0.5463	--	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal circulating interleukin-6 level	0.2634	2.465	--	INHERITED FROM: decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	increased lymphocyte cell number	0.2847	1.863	--	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal B cell morphology	0.3172	1.319	--	INHERITED FROM: abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal lymphocyte physiology	0.3195	1.235	--	INHERITED FROM: abnormal NK T cell physiology || decreased immunoglobulin level || impaired natural killer cell mediated cytotoxicity
Mammalian Phenotype (MP)	vision/eye phenotype	0.3504	0.8972	--	INHERITED FROM: abnormal retinal progenitor cell morphology || abnormal retinal development
Mammalian Phenotype (MP)	abnormal wound healing	0.3598	1.863	--	INHERITED FROM: abnormal vascular wound healing
Mammalian Phenotype (MP)	abnormal interleukin-1 secretion	0.396	1.863	--	INHERITED FROM: abnormal interleukin-1 beta secretion
Mammalian Phenotype (MP)	abnormal interleukin-12 secretion	0.407	2.465	--	INHERITED FROM: decreased interleukin-12 secretion
Mammalian Phenotype (MP)	abnormal tumor necrosis factor level	0.4362	2.465	--	INHERITED FROM: decreased circulating tumor necrosis factor level
Mammalian Phenotype (MP)	abnormal mononuclear cell morphology	0.4612	0.8972	--	INHERITED FROM: abnormal lymphocyte morphology || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal circulating interleukin level	0.4702	1.687	--	INHERITED FROM: decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	skeleton phenotype	0.4926	0.9213	--	INHERITED FROM: decreased susceptibility to induced joint inflammation
Mammalian Phenotype (MP)	abnormal interleukin-10 secretion	0.5062	1.988	--	INHERITED FROM: decreased interleukin-10 secretion
Mammalian Phenotype (MP)	abnormal circulating interferon level	0.546	1.62	--	INHERITED FROM: abnormal circulating interferon-alpha level
Mammalian Phenotype (MP)	increased hematopoietic cell number	0.5559	1.386	--	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal leukocyte physiology	0.6647	1.05	--	INHERITED FROM: abnormal NK T cell physiology || decreased macrophage cytokine production || decreased macrophage nitric oxide production || decreased immunoglobulin level || abnormal macrophage cytokine production || impaired natural killer cell mediated cytotoxicity
Mammalian Phenotype (MP)	decreased acute inflammation	0.6744	2.164	--	INHERITED FROM: decreased susceptibility to endotoxin shock
Mammalian Phenotype (MP)	abnormal natural killer cell mediated cytotoxicity	0.698	1.766	--	INHERITED FROM: impaired natural killer cell mediated cytotoxicity
Mammalian Phenotype (MP)	abnormal circulating enzyme level	0.7046	1.562	--	INHERITED FROM: decreased circulating alanine transaminase level
Mammalian Phenotype (MP)	abnormal circulating tumor necrosis factor level	0.7403	2.465	--	INHERITED FROM: decreased circulating tumor necrosis factor level
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0.782	0.7752	--	INHERITED FROM: abnormal lymphocyte morphology || abnormal leukocyte morphology || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal immune system morphology	0.7932	0.8026	--	INHERITED FROM: abnormal immune system cell morphology || abnormal lymphocyte morphology || abnormal leukocyte morphology || abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	abnormal blood circulation	0.8013	1.261	--	INHERITED FROM: rectal hemorrhage
Mammalian Phenotype (MP)	immune system phenotype	1.172e-07	0.5846	Least Informative	DIRECT
Mammalian Phenotype (MP)	cardiovascular system phenotype	0.2106	0.6801	Least Informative	INHERITED FROM: rectal hemorrhage || abnormal vascular wound healing
Mammalian Phenotype (MP)	cellular phenotype	0.2498	0.516	Least Informative	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal homeostasis	0.2707	0.5209	Least Informative	INHERITED FROM: decreased circulating tumor necrosis factor level || abnormal circulating interferon-alpha level || abnormal protein level || decreased circulating alanine transaminase level || abnormal intercellular signaling peptide or protein level || abnormal circulating protein level || decreased macrophage nitric oxide production || decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	altered susceptibility to infection	9.131e-09	1.143	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal protein level	1.925e-05	1.187	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal immune serum protein physiology	3.277e-05	1.143	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal lymphocyte morphology	0.0003015	1.034	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal immune cell physiology	0.02506	1.034	Moderately Informative	INHERITED FROM: decreased macrophage cytokine production || decreased macrophage nitric oxide production || decreased immunoglobulin level || abnormal NK T cell physiology || abnormal macrophage cytokine production || impaired natural killer cell mediated cytotoxicity || abnormal dendritic cell physiology
Mammalian Phenotype (MP)	abnormal cell-mediated immunity	0.02676	1.034	Moderately Informative	INHERITED FROM: decreased macrophage cytokine production || decreased macrophage nitric oxide production || decreased immunoglobulin level || abnormal NK T cell physiology || abnormal macrophage cytokine production || impaired natural killer cell mediated cytotoxicity || abnormal dendritic cell physiology
Mammalian Phenotype (MP)	renal/urinary system phenotype	0.02727	0.9883	Moderately Informative	INHERITED FROM: abnormal kidney physiology || altered susceptibility to kidney reperfusion injury
Mammalian Phenotype (MP)	abnormal adaptive immunity	0.03093	1.018	Moderately Informative	INHERITED FROM: decreased macrophage cytokine production || decreased macrophage nitric oxide production || decreased immunoglobulin level || abnormal NK T cell physiology || abnormal macrophage cytokine production || impaired natural killer cell mediated cytotoxicity || abnormal dendritic cell physiology
Mammalian Phenotype (MP)	abnormal cardiovascular system physiology	0.03942	0.9602	Moderately Informative	INHERITED FROM: abnormal vascular wound healing || rectal hemorrhage
Mammalian Phenotype (MP)	respiratory system phenotype	0.1097	0.9883	Moderately Informative	INHERITED FROM: abnormal airway responsiveness || abnormal bronchial provocation
Mammalian Phenotype (MP)	digestive/alimentary phenotype	0.1156	1.034	Moderately Informative	INHERITED FROM: rectal hemorrhage || abnormal intestine physiology || large intestinal inflammation || colitis
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0.1345	1.123	Moderately Informative	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal inflammatory response	0.18	1.187	Moderately Informative	INHERITED FROM: decreased susceptibility to endotoxin shock || large intestinal inflammation || colitis || decreased susceptibility to induced joint inflammation
Mammalian Phenotype (MP)	abnormal eye morphology	0.305	0.9469	Moderately Informative	INHERITED FROM: abnormal retinal progenitor cell morphology || abnormal retinal development
Mammalian Phenotype (MP)	abnormal professional antigen presenting cell morphology	0.4018	1.187	Moderately Informative	INHERITED FROM: abnormal B-1 B cell number || increased mature B cell number
Mammalian Phenotype (MP)	increased susceptibility to infection	1.019e-09	1.351	Informative	DIRECT
Mammalian Phenotype (MP)	autoimmune response	0.0001838	1.424	Informative	DIRECT
Mammalian Phenotype (MP)	abnormal kidney physiology	0.0002154	1.511	Informative	DIRECT
Mammalian Phenotype (MP)	abnormal innate immunity	0.001278	1.424	Informative	INHERITED FROM: impaired natural killer cell mediated cytotoxicity || decreased macrophage cytokine production || decreased macrophage nitric oxide production || abnormal macrophage cytokine production
Mammalian Phenotype (MP)	abnormal response to injury	0.001452	1.465	Informative	INHERITED FROM: altered susceptibility to kidney reperfusion injury || abnormal vascular wound healing
Mammalian Phenotype (MP)	abnormal circulating cytokine level	0.002597	1.511	Informative	INHERITED FROM: abnormal circulating interferon-alpha level || decreased circulating tumor necrosis factor level || decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	abnormal humoral immune response	0.006602	1.62	Informative	INHERITED FROM: decreased immunoglobulin level
Mammalian Phenotype (MP)	abnormal digestive system physiology	0.008235	1.465	Informative	INHERITED FROM: large intestinal inflammation || rectal hemorrhage || colitis || abnormal intestine physiology
Mammalian Phenotype (MP)	abnormal gas homeostasis	0.01948	1.562	Informative	INHERITED FROM: decreased macrophage nitric oxide production
Mammalian Phenotype (MP)	abnormal skeleton physiology	0.07363	1.511	Informative	INHERITED FROM: decreased susceptibility to induced joint inflammation
Mammalian Phenotype (MP)	abnormal B cell physiology	0.07504	1.351	Informative	INHERITED FROM: decreased immunoglobulin level
Mammalian Phenotype (MP)	abnormal interleukin secretion	0.09432	1.386	Informative	INHERITED FROM: abnormal interleukin-12b secretion || abnormal interleukin-1 beta secretion || decreased interleukin-12b secretion || decreased interleukin-12 secretion || decreased interleukin-10 secretion
Mammalian Phenotype (MP)	abnormal enzyme/ coenzyme level	0.09704	1.511	Informative	INHERITED FROM: decreased circulating alanine transaminase level
Mammalian Phenotype (MP)	abnormal interferon level	0.1586	1.62	Informative	INHERITED FROM: abnormal circulating interferon-alpha level
Mammalian Phenotype (MP)	abnormal lymphocyte cell number	0.1889	1.465	Informative	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	hemorrhage	0.1894	1.351	Informative	INHERITED FROM: rectal hemorrhage
Mammalian Phenotype (MP)	abnormal blood vessel physiology	0.2006	1.562	Informative	INHERITED FROM: abnormal vascular wound healing
Mammalian Phenotype (MP)	increased inflammatory response	0.226	1.261	Informative	INHERITED FROM: large intestinal inflammation || colitis || decreased susceptibility to induced joint inflammation
Mammalian Phenotype (MP)	abnormal interleukin level	0.2556	1.62	Informative	INHERITED FROM: decreased circulating interleukin-6 level
Mammalian Phenotype (MP)	abnormal cell proliferation	0.3028	1.351	Informative	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal hematopoietic system physiology	0.3896	1.687	Informative	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	increased leukocyte cell number	0.4961	1.424	Informative	INHERITED FROM: increased mature B cell number
Mammalian Phenotype (MP)	abnormal T cell physiology	0.7156	1.465	Informative	INHERITED FROM: abnormal NK T cell physiology
Mammalian Phenotype (MP)	abnormal respiration	0.817	1.465	Informative	INHERITED FROM: abnormal airway responsiveness || abnormal bronchial provocation
Mammalian Phenotype (MP)	decreased interleukin-12b secretion	0	1.988	Highly Informative	DIRECT
Mammalian Phenotype (MP)	colitis	5.453e-06	1.863	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal retinal development	6.569e-05	1.988	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal B-1 B cell number	0.0002606	1.863	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal airway responsiveness	0.0003154	1.766	Highly Informative	DIRECT
Mammalian Phenotype (MP)	impaired natural killer cell mediated cytotoxicity	0.0003974	1.766	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal vascular wound healing	0.0004272	1.988	Highly Informative	DIRECT
Mammalian Phenotype (MP)	decreased interleukin-10 secretion	0.0004272	1.988	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal interleukin-1 beta secretion	0.0008252	1.863	Highly Informative	DIRECT
Mammalian Phenotype (MP)	gastrointestinal hemorrhage	0.001728	2.164	Highly Informative	INHERITED FROM: rectal hemorrhage
Mammalian Phenotype (MP)	abnormal circulating alanine transaminase level	0.00336	1.988	Highly Informative	INHERITED FROM: decreased circulating alanine transaminase level
Mammalian Phenotype (MP)	abnormal macrophage physiology	0.005142	1.988	Highly Informative	INHERITED FROM: decreased macrophage cytokine production || decreased macrophage nitric oxide production || abnormal macrophage cytokine production
Mammalian Phenotype (MP)	abnormal nitric oxide homeostasis	0.006871	1.766	Highly Informative	INHERITED FROM: decreased macrophage nitric oxide production
Mammalian Phenotype (MP)	decreased inflammatory response	0.00699	1.863	Highly Informative	INHERITED FROM: decreased susceptibility to endotoxin shock
Mammalian Phenotype (MP)	abnormal fat cell morphology	0.05581	2.164	Highly Informative	INHERITED FROM: decreased fat cell size
Mammalian Phenotype (MP)	joint inflammation	0.1334	2.164	Highly Informative	INHERITED FROM: decreased susceptibility to induced joint inflammation
Mammalian Phenotype (MP)	abnormal immune organ physiology	0.1987	1.988	Highly Informative	INHERITED FROM: abnormal splenocyte proliferation
Mammalian Phenotype (MP)	abnormal tumor necrosis factor secretion	0.2266	1.863	Highly Informative	INHERITED FROM: decreased tumor necrosis factor secretion
Mammalian Phenotype (MP)	abnormal acute inflammation	0.2935	1.988	Highly Informative	INHERITED FROM: decreased susceptibility to endotoxin shock
Mammalian Phenotype (MP)	abnormal B cell number	0.6528	2.164	Highly Informative	INHERITED FROM: increased mature B cell number