SUPERFAMILY 1.75 HMM library and genome assignments server

Electron transport accessory proteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   SH3-like barrel [ 50036] (21)
Superfamily:   Electron transport accessory proteins [ 50090] (4)
Families:   R67 dihydrofolate reductase [ 50091]
  Photosystem I accessory protein E (PsaE) [ 50094]
  Ferredoxin thioredoxin reductase (FTR), alpha (variable) chain [ 50098]
  Nitrile hydratase beta chain [ 50101] (2)


Superfamily statistics
Genomes (290) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 719 1,516 13
Proteins 719 1,516 13


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.000000752Least InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.0000000002493Moderately InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cotyledon0Moderately InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.0000009601Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.1268Least InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases0.000000002878Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors0.000002045InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processPhotosynthesis0InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentPlastid0.000000000009822Moderately InformativeDirect
Cellular componentThylakoid0InformativeDirect
Cellular componentPhotosystem I0Highly InformativeDirect
DomainTransit peptide0.000003658Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0.003282Least InformativeInherited
UniPathway (UP)aromatic compound metabolism0.003879Least InformativeInherited
UniPathway (UP)aromatic compound biosynthesis0.00001123Moderately InformativeDirect
UniPathway (UP)pteridine biosynthesis0.00000001103InformativeDirect
UniPathway (UP)tetrahydrofolate metabolism0.0000002505InformativeDirect
UniPathway (UP)tetrahydrofolate biosynthesis0.000000000183Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR008990 SSF50090 Protein matches
Abstract

The electron transport accessory proteins adopt the beta topology of an SH3 domain, with a partly opened beta barrel and a 3-10 helical turn interrupting the last strand. Proteins displaying this topology include R67 dihydrofolate reductase, which catalyses the hydration of nitriles to amides [PubMed9195885], photosystem I accessory proteins (PsaE), which participate in cyclic electron transport and modulate the interaction of photosystem I with ferrodoxin [PubMed10521281], the alpha chain of ferrodoxin thioredoxin reductase (FTR), which is involved in the regulation of the activity of chloroplast enzymes [PubMed10649999], and the beta chain of nitrile hydratase, which confers trimethoprim-resistance to R67-expressing bacteria [PubMed12501195].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Electron transport accessory proteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the Electron transport accessory proteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]