SUPERFAMILY 1.75 HMM library and genome assignments server

MetI-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   MetI-like [ 161097]
Superfamily:   MetI-like [ 161098]
Families:   MetI-like [ 161099] (5)


Superfamily statistics
Genomes (2,732) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 91,669 592,184 5
Proteins 87,566 570,064 5


Functional annotation
Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.44511Least InformativeInherited
Biological Process (BP)ion transport0.0000000023530.000001502Moderately InformativeDirect
Biological Process (BP)organic substance transport0.0036160.0000000002077Moderately InformativeInherited
Biological Process (BP)multi-organism process0.043360.4928Moderately InformativeInherited
Biological Process (BP)transmembrane transport00InformativeDirect
Biological Process (BP)nitrogen compound transport0.0000034370InformativeDirect
Biological Process (BP)growth0.00066120.04399InformativeInherited
Biological Process (BP)anion transport0.0069720.000003266InformativeInherited
Biological Process (BP)carbohydrate derivative transport0.10140.005206Highly InformativeInherited
Biological Process (BP)organophosphate ester transport0.12310.02109Highly InformativeInherited
Biological Process (BP)inorganic anion transport0.27220.3611Highly InformativeInherited
Molecular Function (MF)hydrolase activity00Least InformativeDirect
Molecular Function (MF)transporter activity00Moderately InformativeDirect
Molecular Function (MF)nucleoside-triphosphatase activity00InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances00InformativeDirect
Molecular Function (MF)active transmembrane transporter activity0.00000000054590InformativeDirect
Molecular Function (MF)anion transmembrane transporter activity0.00026690.0000000008651InformativeDirect
Molecular Function (MF)amino acid transmembrane transporter activity0.000000000002260Highly InformativeDirect
Molecular Function (MF)ATPase activity, coupled to transmembrane movement of ions0.000007980.0005431Highly InformativeDirect
Molecular Function (MF)carbohydrate transmembrane transporter activity0.2390.08772Highly InformativeInherited
Molecular Function (MF)organic hydroxy compound transmembrane transporter activity0.39870.0104Highly InformativeInherited
Cellular Component (CC)protein complex0.095030.06391Least InformativeInherited
Cellular Component (CC)membrane0.13370.2382Least InformativeInherited
Cellular Component (CC)ATP-binding cassette (ABC) transporter complex0.0000000000000014340Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) ion transport 0.000001502 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.0000000002077 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.4928 Moderately Informative Inherited
Biological Process (BP) transmembrane transport 0 Informative Direct
Biological Process (BP) nitrogen compound transport 0 Informative Direct
Biological Process (BP) organic acid transport 0.000157 Informative Direct
Biological Process (BP) anion transport 0.000003266 Informative Direct
Biological Process (BP) growth 0.04399 Informative Inherited
Biological Process (BP) metal ion transport 1 Informative Inherited
Biological Process (BP) amide transport 0 Highly Informative Direct
Biological Process (BP) transition metal ion transport 0.00000002556 Highly Informative Direct
Biological Process (BP) carbohydrate derivative transport 0.005206 Highly Informative Inherited
Biological Process (BP) organophosphate ester transport 0.02109 Highly Informative Inherited
Biological Process (BP) inorganic anion transport 0.3611 Highly Informative Inherited
Biological Process (BP) amino acid transport 0.132 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0 Informative Direct
Molecular Function (MF) active transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) anion transmembrane transporter activity 0.0000000008651 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.896 Informative Inherited
Molecular Function (MF) amino acid transmembrane transporter activity 0 Highly Informative Direct
Molecular Function (MF) ATPase activity, coupled to transmembrane movement of ions 0.0005431 Highly Informative Direct
Molecular Function (MF) transition metal ion transmembrane transporter activity 0.000000000007855 Highly Informative Direct
Molecular Function (MF) carbohydrate transmembrane transporter activity 0.08772 Highly Informative Inherited
Molecular Function (MF) organic hydroxy compound transmembrane transporter activity 0.0104 Highly Informative Inherited
Cellular Component (CC) membrane 0.2382 Least Informative Inherited
Cellular Component (CC) protein complex 0.06391 Least Informative Inherited
Cellular Component (CC) ATP-binding cassette (ABC) transporter complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0.984Moderately InformativeInherited
Biological processSporulation0.00003091InformativeDirect
Biological processAmino-acid transport0Highly InformativeDirect
Biological processSugar transport0.00000000000002568Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionIron1Moderately InformativeInherited
Molecular functionMolybdenum0InformativeDirect
Molecular functionIron transport0.000002359Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a MetI-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the MetI-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]