SUPERFAMILY 1.75 HMM library and genome assignments server


HAMP domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   HAMP domain-like [ 158471]
Superfamily:   HAMP domain-like [ 158472]
Families:   HAMP domain [ 158473]


Superfamily statistics
Genomes (2,236) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 14,729 37,235 2
Proteins 14,727 37,225 2


Functional annotation
Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 5.196e-05 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.001042 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.001381 Least Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1.022e-10 Moderately Informative Direct
Biological Process (BP) signal transduction 1.177e-06 Moderately Informative Direct
Biological Process (BP) phosphorylation 1.379e-06 Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1.724e-13 Moderately Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 1.555e-15 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 3.054e-15 Informative Direct
Molecular Function (MF) kinase activity 1.322e-14 Informative Direct
Molecular Function (MF) protein kinase activity 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-histidine kinases0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Protein-histidine kinases0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processVirulence0InformativeDirect
Biological processStress response9.569e-07InformativeDirect
Biological processTwo-component regulatory system0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionManganese0.0002084Moderately InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationProtein phosphatase5.027e-15InformativeDirect
Post-translational modificationTransducer1.09e-05InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a HAMP domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the HAMP domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]