SUPERFAMILY 1.75 HMM library and genome assignments server

Sec2 N-terminal region superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Sec2 N-terminal region [ 144284]
Families:   Sec2 N-terminal region [ 144285]


Superfamily statistics
Genomes (328) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 646 730 3
Proteins 646 730 3


Functional annotation
General category Other
Detailed category Viral proteins

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.029 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.4724 Least Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.0000005773 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.000002396 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 0.3076 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.03001 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.00346 Moderately Informative Inherited
Biological Process (BP) regulation of nucleoside metabolic process 0.0000000001188 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 0.0000000006496 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 0.000000001218 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0.000000005901 Informative Direct
Biological Process (BP) positive regulation of GTPase activity 0.00000000001216 Highly Informative Direct
Biological Process (BP) regulation of Ras GTPase activity 0.2846 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.000000000000008977 Moderately Informative Direct
Molecular Function (MF) GTPase regulator activity 0 Informative Direct
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0.001112 Highly Informative Inherited
Molecular Function (MF) small GTPase regulator activity 0.5621 Highly Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.00000005391Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
Post-translational modificationGuanine-nucleotide releasing factor0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Sec2 N-terminal region domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Sec2 N-terminal region superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]