SUPERFAMILY 1.75 HMM library and genome assignments server

Eferin C-derminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Eferin C-derminal domain-like [ 144270]
Families:   Eferin C-derminal domain-like [ 144271] (2)


Superfamily statistics
Genomes (134) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 614 621 3
Proteins 614 621 3


Functional annotation
General category N_A
Detailed category not annotated

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.0000000000412 Least Informative Direct
Biological Process (BP) developmental process 0.0006553 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.0006875 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.002259 Least Informative Inherited
Biological Process (BP) localization 0.002869 Least Informative Inherited
Biological Process (BP) organ development 0.0000002461 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.000001578 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.00002042 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0005359 Moderately Informative Direct
Biological Process (BP) cellular localization 0.0007805 Moderately Informative Direct
Biological Process (BP) organelle organization 0.003819 Moderately Informative Inherited
Biological Process (BP) sensory organ development 0 Informative Direct
Biological Process (BP) organ morphogenesis 0.00000000000005099 Informative Direct
Biological Process (BP) cell cycle process 0.000000000000155 Informative Direct
Biological Process (BP) vesicle-mediated transport 0.000000001293 Informative Direct
Biological Process (BP) microtubule-based process 0.00000003649 Informative Direct
Biological Process (BP) actin filament-based process 0.00000007522 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.000002586 Informative Direct
Biological Process (BP) cytoskeleton organization 0.0006986 Informative Direct
Biological Process (BP) actomyosin structure organization 0 Highly Informative Direct
Biological Process (BP) cell division 0 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0.00000000008574 Highly Informative Direct
Biological Process (BP) pattern specification process 0.00000000285 Highly Informative Direct
Biological Process (BP) cell fate commitment 0.000000006506 Highly Informative Direct
Biological Process (BP) post-embryonic development 0.00000003291 Highly Informative Direct
Molecular Function (MF) binding 0.000000005958 Least Informative Direct
Molecular Function (MF) enzyme binding 0.000000000007498 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.00000001418 Informative Direct
Molecular Function (MF) protein dimerization activity 0.0006496 Informative Direct
Molecular Function (MF) Ras GTPase binding 0 Highly Informative Direct
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 0.0000000002642 Highly Informative Direct
Cellular Component (CC) protein complex 0.00006618 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0002225 Least Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.000499 Least Informative Direct
Cellular Component (CC) membrane 0.09726 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.002382 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0.000002865 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.001312 Moderately Informative Inherited
Cellular Component (CC) vesicle 0.003951 Moderately Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 0 Informative Direct
Cellular Component (CC) cell cortex 0.00000000002422 Informative Direct
Cellular Component (CC) endosome 0.0000000008486 Informative Direct
Cellular Component (CC) centrosome 0 Highly Informative Direct
Cellular Component (CC) cell division site part 0.00000000000008715 Highly Informative Direct
Cellular Component (CC) midbody 0.0000000000002516 Highly Informative Direct
Cellular Component (CC) microtubule associated complex 0.000000000002354 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 0.0000000005561 Highly Informative Direct
Cellular Component (CC) endosomal part 0.000004626 Highly Informative Direct

Document: GO annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)gamete0Moderately InformativeDirect

Document: XA annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processCell cycle0.00000009757Moderately InformativeDirect
Biological processProtein transport0.0001063Moderately InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Coding sequence diversityAlternative splicing0.000000009013Least InformativeDirect
DomainCoiled coil0.0000000000472Moderately InformativeDirect
Molecular functionCalcium0.0000000002667Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0000000004258Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Xenopus Anatomy (XA) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Eferin C-derminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Eferin C-derminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Xenopus Anatomy (XA) · UniProtKB KeyWords (KW) · Internal database links ]