SUPERFAMILY 1.75 HMM library and genome assignments server


Thermophilic metalloprotease-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Thermophilic metalloprotease-like [ 144051]
Superfamily:   Thermophilic metalloprotease-like [ 144052]
Families:   Thermophilic metalloprotease (M29) [ 144053] (2)


Superfamily statistics
Genomes (656) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 934 3,306 2
Proteins 934 3,303 2


Functional annotation
General category Processes_IC
Detailed category Proteases

Document:
Function annotation of SCOP domain superfamilies

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Molecular functionMetal-binding0.0001922Least InformativeDirect
Post-translational modificationHydrolase6.675e-05Least InformativeDirect
Post-translational modificationProtease3.406e-10Moderately InformativeDirect
Post-translational modificationMetalloprotease8.981e-14InformativeDirect
Post-translational modificationAminopeptidase3.503e-15Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Thermophilic metalloprotease-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Thermophilic metalloprotease-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · UniProtKB KeyWords (KW) · Internal database links ]