SUPERFAMILY 1.75 HMM library and genome assignments server

Nqo1C-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bromodomain-like [ 47363] (15)
Superfamily:   Nqo1C-terminal domain-like [ 140490]
Families:   Nqo1C-terminal domain-like [ 140491]


Superfamily statistics
Genomes (1,864) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 2,752 10,681 1
Proteins 2,750 10,674 1


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.002663 Least Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.0009027 Informative Direct
Molecular Function (MF) oxidoreductase activity 0.00000000004021 Moderately Informative Direct
Cellular Component (CC) protein complex 0.000003101 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.05919 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.148 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.07084 Least Informative Inherited
Cellular Component (CC) membrane 0.005561 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.00000004049 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.00000008795 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.000007612 Moderately Informative Direct
Cellular Component (CC) respiratory chain 0.00000000005481 Informative Direct
Cellular Component (CC) respiratory chain complex I 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)With other acceptors0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0Highly InformativeDirect
Enzyme Commission (EC)NADH dehydrogenase0.000006064Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.0001609Least InformativeDirect
Biological processElectron transport0.000000000009598InformativeDirect
Biological processRespiratory chain2.372e-16Highly InformativeDirect
Cellular componentMembrane0.0006495Least InformativeDirect
Cellular componentMitochondrion0.0000000000727Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0.00004269InformativeDirect
DomainTransit peptide0.0000000000003351Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationQuinone0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nqo1C-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Nqo1C-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]