SUPERFAMILY 1.75 HMM library and genome assignments server

Hook domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   CH domain-like [ 47575] (3)
Superfamily:   Hook domain [ 116907]
Families:   Hook domain [ 116908]


Superfamily statistics
Genomes (331) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 926 1,083 1
Proteins 921 1,078 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) multicellular organismal process 0.00009664 Least Informative Direct
Biological Process (BP) developmental process 0.00001575 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000000000006719 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00000001198 Least Informative Direct
Biological Process (BP) regulation of metabolic process 0.9042 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0.0001495 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.1435 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.001809 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 0.01182 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.01696 Moderately Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.0007517 Informative Direct
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) cytoplasmic transport 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.001236 Informative Inherited
Biological Process (BP) lysosome organization 0 Highly Informative Direct
Biological Process (BP) aging 0.000000001116 Highly Informative Direct
Biological Process (BP) regulation of cell size 0.0000001877 Highly Informative Direct
Biological Process (BP) cytoskeleton-dependent intracellular transport 0 Highly Informative Direct
Molecular Function (MF) binding 0.000001897 Least Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0 Informative Direct
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.0007187 Least Informative Direct
Cellular Component (CC) protein complex 0.03108 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.1335 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.948 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.8391 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0.008456 Moderately Informative Inherited
Cellular Component (CC) endosome 0.00000000000009106 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0.0000001773 Informative Direct
Cellular Component (CC) centrosome 0.00001621 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.001472Least InformativeInherited
Biological processProtein transport0.0000000000003141Moderately InformativeDirect
Biological processEndocytosis0InformativeDirect
Cellular componentCytoplasm0.000000000006038Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentMicrotubule0InformativeDirect
Cellular componentSynapse0InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0000005259Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Hook domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Hook domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]