SUPERFAMILY 1.75 HMM library and genome assignments server

Fzo-like conserved region superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Antiparallel coiled-coil [ 58086] (17)
Superfamily:   Fzo-like conserved region [ 111479]
Families:   Fzo-like conserved region [ 111480]


Superfamily statistics
Genomes (132) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 241 261 1
Proteins 241 261 1


Functional annotation
General category coiled coil
Detailed category The code refers to a Dimeric_canonical_antiparallel_coiled_coils in the CC+ database. Please click on the link for more information and to visit the CC+ website.

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.0371 Least Informative Inherited
Biological Process (BP) localization 0.005499 Least Informative Inherited
Biological Process (BP) developmental process 0.09314 Least Informative Inherited
Biological Process (BP) organelle organization 0.000000007191 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.0008468 Moderately Informative Direct
Biological Process (BP) cellular localization 0.005362 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.006759 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.002039 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.007067 Moderately Informative Inherited
Biological Process (BP) mitochondrion organization 0 Informative Direct
Biological Process (BP) protein transport 0.0000002691 Informative Direct
Biological Process (BP) cellular membrane organization 0 Informative Direct
Biological Process (BP) protein localization to organelle 0.00000001984 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.0000138 Informative Direct
Biological Process (BP) cell cycle process 0.001708 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.0377 Informative Inherited
Biological Process (BP) mitochondrial transport 0.000000009312 Highly Informative Direct
Biological Process (BP) mitochondrial membrane organization 0.0001392 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.00000003114 Highly Informative Direct
Biological Process (BP) negative regulation of cell cycle 0.0000000002863 Highly Informative Direct
Biological Process (BP) organelle fusion 0 Highly Informative Direct
Biological Process (BP) regulation of smooth muscle cell proliferation 0.0000000000005298 Highly Informative Direct
Biological Process (BP) membrane fusion 0.00001484 Highly Informative Direct
Biological Process (BP) protein localization to mitochondrion 0.0000000000002252 Highly Informative Direct
Biological Process (BP) establishment of protein localization to organelle 0.0000000002072 Highly Informative Direct
Molecular Function (MF) binding 0.00695 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.0001239 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.00001066 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.08856 Least Informative Inherited
Cellular Component (CC) membrane 0.02077 Least Informative Inherited
Cellular Component (CC) organelle membrane 0.0002978 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 0.00002058 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.000002699 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.000001381 Moderately Informative Direct
Cellular Component (CC) mitochondrial membrane part 0.00000003824 Informative Direct
Cellular Component (CC) intrinsic to organelle membrane 0.0000000004886 Highly Informative Direct
Cellular Component (CC) organelle outer membrane 0.00000000007087 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion outer membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationUbl conjugation0.000000008498Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Fzo-like conserved region domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Fzo-like conserved region superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]