SUPERFAMILY 1.75 HMM library and genome assignments server

Geminin coiled-coil domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Geminin coiled-coil domain [ 111469]
Families:   Geminin coiled-coil domain [ 111470]


Superfamily statistics
Genomes (131) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 226 251 3
Proteins 226 250 3


Functional annotation
General category coiled coil
Detailed category The code refers to a Dimeric_canonical_parallel_coiled_coils in the CC+ database. Please click on the link for more information and to visit the CC+ website.

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.00002471 Least Informative Direct
Biological Process (BP) developmental process 0.00000008346 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00001753 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.1168 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.001425 Least Informative Inherited
Biological Process (BP) organelle organization 0.00004981 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.000000000009001 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0.0000001963 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.0000005282 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.0000003222 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0003066 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.002717 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.2093 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.01098 Moderately Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.0007001 Informative Direct
Biological Process (BP) cell projection organization 0.0000000171 Informative Direct
Biological Process (BP) cellular component morphogenesis 0.000001914 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.000004441 Informative Direct
Biological Process (BP) organelle assembly 0.00000000000002793 Informative Direct
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.01748 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.006987 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.0107 Informative Inherited
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 0.004966 Informative Inherited
Biological Process (BP) cellular component assembly involved in morphogenesis 0.00000000005419 Highly Informative Direct
Biological Process (BP) cell projection assembly 0 Highly Informative Direct
Biological Process (BP) cilium organization 0 Highly Informative Direct
Biological Process (BP) positive regulation of transcription, DNA-dependent 0.002674 Highly Informative Inherited
Biological Process (BP) cell part morphogenesis 0.02464 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.0007642 Least Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0Moderately InformativeDirect
Biological processTranscription regulation0.0000000005463Moderately InformativeDirect
Biological processCilium biogenesis/degradation0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainCoiled coil0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Geminin coiled-coil domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Geminin coiled-coil domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]