SUPERFAMILY 1.75 HMM library and genome assignments server


HlyD-like secretion proteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   HlyD-like secretion proteins [ 111368]
Superfamily:   HlyD-like secretion proteins [ 111369]
Families:   HlyD-like secretion proteins [ 111370]


Superfamily statistics
Genomes (1,408) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 17,278 65,047 2
Proteins 13,784 50,554 2


Functional annotation
General category Processes_IC
Detailed category Ion metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details) Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 1.06e-09 Least Informative Direct
Biological Process (BP) response to stimulus 0.04136 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.002655 Least Informative Inherited
Biological Process (BP) cellular localization 0.002896 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.1197 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.1663 Moderately Informative Inherited
Biological Process (BP) transmembrane transport 4.008e-15 Informative Direct
Biological Process (BP) secretion 0.0004829 Informative Direct
Biological Process (BP) protein transport 0.001847 Informative Inherited
Biological Process (BP) response to drug 2.984e-12 Highly Informative Direct
Biological Process (BP) response to toxic substance 0.0001315 Highly Informative Direct
Molecular Function (MF) transporter activity 1.772e-11 Moderately Informative Direct
Molecular Function (MF) protein transporter activity 1.486e-13 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAntibiotic resistance0InformativeDirect
Biological processCytolysis1.449e-07InformativeDirect
Biological processHemolysis9.805e-09Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentPeriplasm0InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainSignal0Least InformativeDirect
DomainCoiled coil8.77e-12Moderately InformativeDirect
Post-translational modificationPalmitate1.728e-11Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a HlyD-like secretion proteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the HlyD-like secretion proteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]