SUPERFAMILY 1.75 HMM library and genome assignments server


BAR/IMD domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   BAR/IMD domain-like [ 116747]
Superfamily:   BAR/IMD domain-like [ 103657] (4)
Families:   BAR domain [ 103658] (3)
  Arfaptin, Rac-binding fragment [ 64599]
  IMD domain [ 140703]
  FCH domain [ 158645] (2)


Superfamily statistics
Genomes (478) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 12,571 11,177 12
Proteins 12,374 11,086 12


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process2.111e-063.836e-12Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00083051.336e-13Least InformativeDirect
Biological Process (BP)regulation of metabolic process0.27141Least InformativeInherited
Biological Process (BP)regulation of cellular process7.656e-060.008926Least InformativeInherited
Biological Process (BP)localization0.0011611.711e-13Least InformativeInherited
Biological Process (BP)multicellular organismal process0.055770.7236Least InformativeInherited
Biological Process (BP)regulation of localization3.162e-079.225e-11Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization3.562e-070Moderately InformativeDirect
Biological Process (BP)negative regulation of cellular process0.4710.7448Moderately InformativeInherited
Biological Process (BP)system process0.00022370.002669Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.074970.0002912Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.14630.001191Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.050540.0001419Moderately InformativeInherited
Biological Process (BP)regulation of cellular metabolic process0.097521Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.58570.1745Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.43071Moderately InformativeInherited
Biological Process (BP)regulation of nitrogen compound metabolic process0.084940.501Moderately InformativeInherited
Biological Process (BP)organelle organization0.014511.561e-05Moderately InformativeInherited
Biological Process (BP)synaptic transmission4.809e-092.124e-05InformativeDirect
Biological Process (BP)vesicle-mediated transport6.089e-070InformativeDirect
Biological Process (BP)negative regulation of cellular component organization1.751e-062.927e-09InformativeDirect
Biological Process (BP)regulation of hydrolase activity1.007e-054.846e-08InformativeDirect
Biological Process (BP)positive regulation of catalytic activity1.38e-059.019e-05InformativeDirect
Biological Process (BP)actin filament-based process4.357e-050InformativeDirect
Biological Process (BP)cytoskeleton organization0.00018142.639e-10InformativeDirect
Biological Process (BP)regulation of cellular catabolic process0.00025880InformativeDirect
Biological Process (BP)regulation of system process7.639e-050.02448InformativeInherited
Biological Process (BP)regulation of vesicle-mediated transport00Highly InformativeDirect
Biological Process (BP)synaptic vesicle transport7.59e-121.158e-14Highly InformativeDirect
Biological Process (BP)regulation of purine nucleotide catabolic process2.79e-090Highly InformativeDirect
Biological Process (BP)regulation of nucleoside metabolic process8.29e-070Highly InformativeDirect
Biological Process (BP)regulation of neurological system process4.113e-060.0005776Highly InformativeDirect
Biological Process (BP)regulation of Ras protein signal transduction2.307e-081Highly InformativeInherited
Molecular Function (MF)binding2.673e-069.221e-14Least InformativeDirect
Molecular Function (MF)protein binding5.101e-114.09e-10Moderately InformativeDirect
Molecular Function (MF)enzyme regulator activity0.00023941.031e-10Moderately InformativeDirect
Molecular Function (MF)GTPase regulator activity4.215e-090InformativeDirect
Molecular Function (MF)cytoskeletal protein binding1.031e-084.411e-08InformativeDirect
Molecular Function (MF)enzyme activator activity4.732e-080InformativeDirect
Molecular Function (MF)GTPase activator activity4.512e-120Highly InformativeDirect
Molecular Function (MF)small GTPase regulator activity0.0071880.001369Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle0.58490.005372Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)cell projection0.015073.695e-08Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.014751.411e-11Moderately InformativeInherited
Cellular Component (CC)synapse2.834e-055.863e-12InformativeDirect
Cellular Component (CC)actin cytoskeleton0.00031415.79e-11InformativeDirect
Cellular Component (CC)cell projection part0.0004421.874e-06InformativeDirect
Cellular Component (CC)neuron part0.0065099.874e-06InformativeInherited
Cellular Component (CC)trans-Golgi network2.93e-111.814e-08Highly InformativeDirect
Cellular Component (CC)axon part0.00160.001044Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 3.836e-12 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1.336e-13 Least Informative Direct
Biological Process (BP) localization 1.711e-13 Least Informative Direct
Biological Process (BP) developmental process 0.3664 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.008926 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.7236 Least Informative Inherited
Biological Process (BP) response to stimulus 0.8086 Least Informative Inherited
Biological Process (BP) regulation of localization 9.225e-11 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0 Moderately Informative Direct
Biological Process (BP) organelle organization 1.561e-05 Moderately Informative Direct
Biological Process (BP) regulation of molecular function 0.0001419 Moderately Informative Direct
Biological Process (BP) regulation of signaling 0.0002912 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0001355 Moderately Informative Direct
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.003165 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.001564 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.588 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.7716 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.7448 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.03323 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.001191 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.005398 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.4377 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.1745 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 0.501 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) system process 0.002669 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.2306 Moderately Informative Inherited
Biological Process (BP) synaptic transmission 2.124e-05 Informative Direct
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 2.927e-09 Informative Direct
Biological Process (BP) regulation of hydrolase activity 4.846e-08 Informative Direct
Biological Process (BP) positive regulation of catalytic activity 9.019e-05 Informative Direct
Biological Process (BP) actin filament-based process 0 Informative Direct
Biological Process (BP) cytoskeleton organization 2.639e-10 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0 Informative Direct
Biological Process (BP) cellular membrane organization 1.941e-11 Informative Direct
Biological Process (BP) cell projection organization 2.757e-07 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 7.096e-06 Informative Direct
Biological Process (BP) generation of neurons 9.51e-05 Informative Direct
Biological Process (BP) regulation of nervous system development 0.0005552 Informative Direct
Biological Process (BP) intracellular signal transduction 0.0009333 Informative Direct
Biological Process (BP) regulation of locomotion 0.01027 Informative Inherited
Biological Process (BP) tube development 0.1472 Informative Inherited
Biological Process (BP) epithelium development 0.2164 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.1948 Informative Inherited
Biological Process (BP) cell proliferation 0.002458 Informative Inherited
Biological Process (BP) regulation of organelle organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component movement 0.001062 Informative Inherited
Biological Process (BP) regulation of system process 0.02448 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.9905 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.003444 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.03185 Informative Inherited
Biological Process (BP) positive regulation of immune system process 0.3662 Informative Inherited
Biological Process (BP) regulation of immune response 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.002544 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.6215 Informative Inherited
Biological Process (BP) protein phosphorylation 0.09427 Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Informative Inherited
Biological Process (BP) regulation of cell development 0.01395 Informative Inherited
Biological Process (BP) regulation of growth 0.8495 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.04254 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.005042 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.003803 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0 Highly Informative Direct
Biological Process (BP) synaptic vesicle transport 1.158e-14 Highly Informative Direct
Biological Process (BP) regulation of purine nucleotide catabolic process 0 Highly Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 0 Highly Informative Direct
Biological Process (BP) regulation of neurological system process 0.0005776 Highly Informative Direct
Biological Process (BP) actin filament organization 0.0002256 Highly Informative Direct
Biological Process (BP) small GTPase mediated signal transduction 5.816e-12 Highly Informative Direct
Biological Process (BP) regulation of actin cytoskeleton organization 1.941e-10 Highly Informative Direct
Biological Process (BP) vesicle organization 2.823e-09 Highly Informative Direct
Biological Process (BP) plasma membrane organization 1.955e-07 Highly Informative Direct
Biological Process (BP) monoamine transport 2.633e-05 Highly Informative Direct
Biological Process (BP) protein localization to membrane 4.637e-05 Highly Informative Direct
Biological Process (BP) kidney development 0.0001217 Highly Informative Direct
Biological Process (BP) endosomal transport 0.0003006 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 0.0006789 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 0.0007432 Highly Informative Direct
Biological Process (BP) peptidyl-tyrosine phosphorylation 0.0007578 Highly Informative Direct
Biological Process (BP) positive regulation of immune effector process 0.0008865 Highly Informative Direct
Biological Process (BP) epithelial tube morphogenesis 0.005924 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.02095 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.1541 Highly Informative Inherited
Biological Process (BP) organelle assembly 0.166 Highly Informative Inherited
Biological Process (BP) organelle fusion 0.04238 Highly Informative Inherited
Biological Process (BP) cellular membrane fusion 1 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.1017 Highly Informative Inherited
Biological Process (BP) cell projection assembly 0.01568 Highly Informative Inherited
Biological Process (BP) regulation of Ras protein signal transduction 1 Highly Informative Inherited
Biological Process (BP) regulation of protein complex assembly 0.1415 Highly Informative Inherited
Biological Process (BP) establishment or maintenance of cell polarity 0.1919 Highly Informative Inherited
Biological Process (BP) protein polymerization 0.001296 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.1114 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis 0.478 Highly Informative Inherited
Biological Process (BP) regulation of cellular component size 0.001607 Highly Informative Inherited
Biological Process (BP) G-protein coupled receptor signaling pathway 0.4553 Highly Informative Inherited
Molecular Function (MF) binding 9.221e-14 Least Informative Direct
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) protein binding 4.09e-10 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 1.031e-10 Moderately Informative Direct
Molecular Function (MF) anion binding 3.908e-12 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) GTPase regulator activity 0 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 4.411e-08 Informative Direct
Molecular Function (MF) enzyme activator activity 0 Informative Direct
Molecular Function (MF) lipid binding 0 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.3891 Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.1564 Informative Inherited
Molecular Function (MF) enzyme binding 0.0658 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.7588 Informative Inherited
Molecular Function (MF) kinase activity 0.911 Informative Inherited
Molecular Function (MF) GTPase activator activity 0 Highly Informative Direct
Molecular Function (MF) O-acyltransferase activity 8.377e-06 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 5.276e-05 Highly Informative Direct
Molecular Function (MF) small GTPase regulator activity 0.001369 Highly Informative Inherited
Molecular Function (MF) protein kinase activity 0.599 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.001671 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 0.001416 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.005372 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 1.411e-11 Moderately Informative Direct
Cellular Component (CC) cell projection 3.695e-08 Moderately Informative Direct
Cellular Component (CC) vesicle 2.163e-11 Moderately Informative Direct
Cellular Component (CC) organelle membrane 2.371e-05 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.0004917 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.01873 Moderately Informative Inherited
Cellular Component (CC) synapse 5.863e-12 Informative Direct
Cellular Component (CC) actin cytoskeleton 5.79e-11 Informative Direct
Cellular Component (CC) cell projection part 1.874e-06 Informative Direct
Cellular Component (CC) neuron part 9.874e-06 Informative Direct
Cellular Component (CC) endosome 0 Informative Direct
Cellular Component (CC) cell leading edge 1.178e-07 Informative Direct
Cellular Component (CC) cell junction 9.012e-05 Informative Direct
Cellular Component (CC) cell cortex 0.0003129 Informative Direct
Cellular Component (CC) trans-Golgi network 1.814e-08 Highly Informative Direct
Cellular Component (CC) endosomal part 0 Highly Informative Direct
Cellular Component (CC) coated pit 1.894e-10 Highly Informative Direct
Cellular Component (CC) internal side of plasma membrane 4.023e-09 Highly Informative Direct
Cellular Component (CC) extrinsic to plasma membrane 3.191e-08 Highly Informative Direct
Cellular Component (CC) cell division site part 3.453e-06 Highly Informative Direct
Cellular Component (CC) ruffle 8.568e-06 Highly Informative Direct
Cellular Component (CC) adherens junction 2.844e-05 Highly Informative Direct
Cellular Component (CC) synaptic membrane 4.146e-05 Highly Informative Direct
Cellular Component (CC) actin filament 4.502e-05 Highly Informative Direct
Cellular Component (CC) vesicle membrane 0.0001488 Highly Informative Direct
Cellular Component (CC) axon part 0.001044 Highly Informative Inherited
Cellular Component (CC) cell-substrate junction 0.047 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.1986Least InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.4965Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.5165Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron physiology0.1485InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic vesicle recycling5.958e-08Highly InformativeDirect
Mammalian Phenotype (MP)decreased excitatory postsynaptic current amplitude5.91e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal synapse morphology0.008895Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.0719Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.1434Moderately InformativeInherited
Worm Phenotype (WP)sensillum morphology variant0.08915InformativeInherited
Worm Phenotype (WP)cell division variant0.1777InformativeInherited
Worm Phenotype (WP)cleavage furrow defective early emb0.0004289Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0.3802Least InformativeInherited
Fly Anatomy (FA)organ system0.3858Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.044Moderately InformativeInherited
Fly Anatomy (FA)cell component0.004721InformativeInherited

Document: FA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Protein-tyrosine kinases0InformativeDirect
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.002269Least InformativeInherited
Biological processProtein transport0Moderately InformativeDirect
Biological processDifferentiation0.0003723Moderately InformativeDirect
Biological processCell cycle0.001422Moderately InformativeInherited
Biological processEndocytosis0InformativeDirect
Biological processNeurogenesis1.205e-14InformativeDirect
Biological processAutophagy5.86e-15Highly InformativeDirect
Biological processSeptation7.2e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasm1.604e-14Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Cellular componentMitochondrion1Moderately InformativeInherited
Cellular componentLysosome2.199e-08InformativeDirect
Cellular componentMitochondrion outer membrane1.533e-05InformativeDirect
Cellular componentVacuole0.0009283InformativeDirect
Cellular componentCoated pit5.063e-14Highly InformativeDirect
Coding sequence diversityAlternative splicing0.0005602Least InformativeDirect
Coding sequence diversityChromosomal rearrangement0.0001048InformativeDirect
DiseaseProto-oncogene3.985e-05Moderately InformativeDirect
DiseaseTumor suppressor0.0002846Moderately InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
DomainSH3 domain0InformativeDirect
DomainANK repeat1.55e-12InformativeDirect
DomainSH2 domain2.686e-08InformativeDirect
DomainSH3-binding8.069e-05InformativeDirect
Molecular functionZinc0.000394Least InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionZinc-finger6.134e-11Moderately InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Molecular functionActin-binding5.232e-06InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationKinase0.7932Moderately InformativeInherited
Post-translational modificationGTPase activation0InformativeDirect
Post-translational modificationTyrosine-protein kinase1.339e-12Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a BAR/IMD domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 8 hidden Markov models representing the BAR/IMD domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]