SUPERFAMILY 1.75 HMM library and genome assignments server

GyrA/ParC C-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   6-bladed beta-propeller [ 50938] (11)
Superfamily:   GyrA/ParC C-terminal domain-like [ 101904]
Families:   GyrA/ParC C-terminal domain-like [ 101905] (2)


Superfamily statistics
Genomes (2,728) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,569 30,267 2
Proteins 4,508 30,072 2


Functional annotation
General category Information
Detailed category DNA replication/repair

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 0.000000004176 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.000000004901 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.000000009684 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.00000001608 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.00000002425 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0000001042 Least Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.00000000000006719 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.0000000000005038 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.0000000000007155 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.0000000001344 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.00001127 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.00002442 Moderately Informative Direct
Biological Process (BP) DNA metabolic process 0.00000000000004447 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0.0000000000001457 Informative Direct
Biological Process (BP) organophosphate catabolic process 0.000006583 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0.00001294 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0.00001887 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0.0000473 Informative Direct
Biological Process (BP) purine ribonucleotide metabolic process 0.6008 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 0.001961 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 0.01607 Informative Inherited
Biological Process (BP) nucleoside monophosphate catabolic process 0 Highly Informative Direct
Biological Process (BP) purine ribonucleoside monophosphate metabolic process 0.000000000000003755 Highly Informative Direct
Biological Process (BP) ribonucleoside triphosphate catabolic process 0.00000000000002119 Highly Informative Direct
Biological Process (BP) purine nucleoside triphosphate catabolic process 0.00000000000002292 Highly Informative Direct
Biological Process (BP) purine ribonucleoside catabolic process 0.00000000000003126 Highly Informative Direct
Biological Process (BP) purine ribonucleotide catabolic process 0.00000000000003459 Highly Informative Direct
Biological Process (BP) purine ribonucleoside triphosphate metabolic process 0.00000000000003788 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.0006935 Least Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0.000000000001777 Informative Direct
Cellular Component (CC) protein complex 0.0001164 Least Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for isomerases that do not belon1InformativeInherited

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)DNA topoisomerase (ATP-hydrolyzing)0Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)antiinfectives for systemic use0Least InformativeDirect
Drugbank ATC_code (DB)sensory organs0.0004965Least InformativeDirect
Drugbank ATC_code (DB)antibacterials for systemic use0Moderately InformativeDirect
Drugbank ATC_code (DB)antiinfectives0.000001164Moderately InformativeDirect
Drugbank ATC_code (DB)quinolone antibacterials0InformativeDirect
Drugbank ATC_code (DB)fluoroquinolones0.00000000002824InformativeDirect
Drugbank ATC_code (DB)besifloxacin0.000000000001798Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAntibiotic resistance0InformativeDirect
Cellular componentMembrane0.1676Least InformativeInherited
Cellular componentCell membrane0.00000000002432Moderately InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Molecular functionNucleotide-binding0.0000000000004802Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationTopoisomerase0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GyrA/ParC C-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the GyrA/ParC C-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · Internal database links ]