SUPERFAMILY 1.75 HMM library and genome assignments server

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FYSH domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   FYSH domain [ 89894]
Superfamily:   FYSH domain [ 89895] (2)
Families:   Hypothetical protein Yhr087W [ 89896]
  Hypothetical protein AF0491, N-terminal domain [ 110893]


Superfamily statistics
Genomes (631) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 922 1,246 3
Proteins 921 1,245 3


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.00003074 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.2918 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.02413 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.05709 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.1172 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.02206 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.03512 Least Informative Inherited
Biological Process (BP) organelle organization 0.0001934 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0.000193 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.000000391 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0000000003114 Moderately Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 0 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 0.0000000001304 Informative Direct
Biological Process (BP) organelle assembly 0.000000000007902 Informative Direct
Biological Process (BP) ribonucleoprotein complex subunit organization 0.000000000000003755 Highly Informative Direct
Molecular Function (MF) binding 0.8723 Least Informative Inherited
Molecular Function (MF) ribonucleoprotein complex binding 0 Highly Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.00001646 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.00267 Least Informative Inherited
Cellular Component (CC) protein complex 0.7132 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0.005277 Moderately Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 0.000000005321 Informative Direct
Cellular Component (CC) spindle 0.00000000004622 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processRibosome biogenesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus0.0000000000003481Least InformativeDirect
Cellular componentCytoskeleton0.00000000001351Moderately InformativeDirect
Post-translational modificationAcetylation0.00000001552Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a FYSH domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the FYSH domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]