SUPERFAMILY 1.75 HMM library and genome assignments server


BRCA2 tower domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   BRCA2 tower domain [ 81877]
Superfamily:   BRCA2 tower domain [ 81878]
Families:   BRCA2 tower domain [ 81879]


Superfamily statistics
Genomes (114) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 138 129 3
Proteins 137 129 3


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 4.119e-08 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 1.955e-07 Least Informative Direct
Biological Process (BP) regulation of metabolic process 0.0001977 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 8.233e-07 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 3.499e-08 Least Informative Direct
Biological Process (BP) response to stimulus 2.008e-05 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.0002647 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 8.026e-08 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.002029 Least Informative Inherited
Biological Process (BP) developmental process 0.001071 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.003638 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.02387 Least Informative Inherited
Biological Process (BP) reproduction 8.85e-07 Moderately Informative Direct
Biological Process (BP) organelle organization 0.0006194 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 6.85e-06 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1.331e-05 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 9.701e-06 Moderately Informative Direct
Biological Process (BP) cellular response to stress 3.058e-11 Moderately Informative Direct
Biological Process (BP) DNA metabolic process 4.444e-13 Informative Direct
Biological Process (BP) response to DNA damage stimulus 3.114e-14 Informative Direct
Biological Process (BP) cell cycle process 2.471e-08 Informative Direct
Biological Process (BP) single organism reproductive process 3.023e-05 Informative Direct
Biological Process (BP) reproductive structure development 8.425e-06 Informative Direct
Biological Process (BP) cellular process involved in reproduction 7.046e-06 Informative Direct
Biological Process (BP) sexual reproduction 0.01469 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.03692 Informative Inherited
Biological Process (BP) double-strand break repair 0 Highly Informative Direct
Biological Process (BP) DNA recombination 0.0005481 Highly Informative Direct
Biological Process (BP) meiosis 0.0002425 Highly Informative Direct
Biological Process (BP) spermatogenesis 7.371e-10 Highly Informative Direct
Molecular Function (MF) binding 0.001386 Least Informative Inherited

Document: GO annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a BRCA2 tower domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the BRCA2 tower domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Internal database links ]