SUPERFAMILY 1.75 HMM library and genome assignments server


ABC transporter involved in vitamin B12 uptake, BtuC superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   ABC transporter involved in vitamin B12 uptake, BtuC [ 81346]
Superfamily:   ABC transporter involved in vitamin B12 uptake, BtuC [ 81345]
Families:   ABC transporter involved in vitamin B12 uptake, BtuC [ 75648]


Superfamily statistics
Genomes (2,534) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 13,867 43,356 1
Proteins 13,416 41,477 1


Functional annotation
General category Processes_IC
Detailed category Transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0091230.0585Least InformativeInherited
Biological Process (BP)ion transport0.00090840.0003884Moderately InformativeDirect
Biological Process (BP)homeostatic process3.437e-071.093e-05Moderately InformativeDirect
Biological Process (BP)cation homeostasis2.417e-093.064e-08InformativeDirect
Biological Process (BP)cellular chemical homeostasis3.174e-092.888e-08InformativeDirect
Biological Process (BP)transmembrane transport1.314e-110InformativeDirect
Biological Process (BP)metal ion transport0.3230.9563InformativeInherited
Biological Process (BP)transition metal ion transport3.573e-123.773e-14Highly InformativeDirect
Biological Process (BP)transition metal ion homeostasis4.205e-121.553e-11Highly InformativeDirect
Molecular Function (MF)hydrolase activity7.429e-093.194e-11Least InformativeDirect
Molecular Function (MF)transporter activity00Moderately InformativeDirect
Molecular Function (MF)nucleoside-triphosphatase activity00InformativeDirect
Molecular Function (MF)active transmembrane transporter activity0.0069765.523e-05InformativeInherited
Molecular Function (MF)metal ion transmembrane transporter activity0.046940.5959InformativeInherited
Molecular Function (MF)inorganic cation transmembrane transporter activity0.98151InformativeInherited
Molecular Function (MF)transition metal ion transmembrane transporter activity7.524e-143.054e-15Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0585 Least Informative Inherited
Biological Process (BP) ion transport 0.0003884 Moderately Informative Direct
Biological Process (BP) homeostatic process 1.093e-05 Moderately Informative Direct
Biological Process (BP) cation homeostasis 3.064e-08 Informative Direct
Biological Process (BP) cellular chemical homeostasis 2.888e-08 Informative Direct
Biological Process (BP) transmembrane transport 0 Informative Direct
Biological Process (BP) metal ion transport 0.9563 Informative Inherited
Biological Process (BP) transition metal ion transport 3.773e-14 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 1.553e-11 Highly Informative Direct
Molecular Function (MF) hydrolase activity 3.194e-11 Least Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) active transmembrane transporter activity 5.523e-05 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.5959 Informative Inherited
Molecular Function (MF) inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) transition metal ion transmembrane transporter activity 3.054e-15 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentCell inner membrane1.018e-07InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionZinc0.6137Least InformativeInherited
Molecular functionIron2.561e-13Moderately InformativeDirect
Molecular functionZinc transport0Highly InformativeDirect
Molecular functionIron transport0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ABC transporter involved in vitamin B12 uptake, BtuC domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the ABC transporter involved in vitamin B12 uptake, BtuC superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]