SUPERFAMILY 1.75 HMM library and genome assignments server

ABC transporter involved in vitamin B12 uptake, BtuC superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   ABC transporter involved in vitamin B12 uptake, BtuC [ 81346]
Superfamily:   ABC transporter involved in vitamin B12 uptake, BtuC [ 81345]
Families:   ABC transporter involved in vitamin B12 uptake, BtuC [ 75648]


Superfamily statistics
Genomes (2,525) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 13,734 120,853 1
Proteins 13,285 117,127 1


Functional annotation
General category Processes_IC
Detailed category Transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0094850.06113Least InformativeInherited
Biological Process (BP)ion transport0.00084050.0003909Moderately InformativeDirect
Biological Process (BP)regulation of biological quality0.000099360.002302Moderately InformativeInherited
Biological Process (BP)cation homeostasis0.0000000034890.00000004327InformativeDirect
Biological Process (BP)cellular chemical homeostasis0.0000000033040.00000003266InformativeDirect
Biological Process (BP)transmembrane transport0.000000000014650.000000000000001938InformativeDirect
Biological Process (BP)metal ion transport0.33860.9768InformativeInherited
Biological Process (BP)transition metal ion transport0.0000000000032010.00000000000003627Highly InformativeDirect
Biological Process (BP)transition metal ion homeostasis0.0000000000053640.00000000002306Highly InformativeDirect
Molecular Function (MF)hydrolase activity0.0000000068990.00000000003111Least InformativeDirect
Molecular Function (MF)transporter activity00Moderately InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances0.000000013340.0000000000497InformativeDirect
Molecular Function (MF)nucleoside-triphosphatase activity00InformativeDirect
Molecular Function (MF)active transmembrane transporter activity0.0057130.00005481InformativeInherited
Molecular Function (MF)metal ion transmembrane transporter activity0.050450.6128InformativeInherited
Molecular Function (MF)inorganic cation transmembrane transporter activity0.99161InformativeInherited
Molecular Function (MF)transition metal ion transmembrane transporter activity0.000000000000088410.000000000000003078Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.06113 Least Informative Inherited
Biological Process (BP) ion transport 0.0003909 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.002302 Moderately Informative Inherited
Biological Process (BP) cation homeostasis 0.00000004327 Informative Direct
Biological Process (BP) cellular chemical homeostasis 0.00000003266 Informative Direct
Biological Process (BP) transmembrane transport 0.000000000000001938 Informative Direct
Biological Process (BP) metal ion transport 0.9768 Informative Inherited
Biological Process (BP) transition metal ion transport 0.00000000000003627 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 0.00000000002306 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.00000000003111 Least Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.0000000000497 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) active transmembrane transporter activity 0.00005481 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.6128 Informative Inherited
Molecular Function (MF) inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) transition metal ion transmembrane transporter activity 0.000000000000003078 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentCell inner membrane0.00000008305InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionZinc0.6305Least InformativeInherited
Molecular functionIron0.0000000000002157Moderately InformativeDirect
Molecular functionZinc transport0Highly InformativeDirect
Molecular functionIron transport0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ABC transporter involved in vitamin B12 uptake, BtuC domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the ABC transporter involved in vitamin B12 uptake, BtuC superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]