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Gated mechanosensitive channel superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | coiled coil |
| Detailed category | The code refers to alpha-helical barrels. These are a type of structure which frequently contain coiled-coils. |
Document: Function annotation of SCOP domain superfamilies
UniProtKB KeyWords (KW) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: KW annotation of SCOP domains
InterPro annotation
| Cross references | IPR001185 SSF81330 Protein matches |
| Abstract | Mechanosensitive ion channels (MscL) play a critical role in transducing physical stresses
at the cell membrane into an electrochemical response. MscL is a protein which forms a
channel organised as a homopentamer, with each subunit containing two transmembrane
regions [ 9856938]. Prokaryotes harbor a
large-conductance mechanosensitive channel (gene mscL) that opens in response to stretch
forces in the membrane lipid bilayer and may participate in the regulation of osmotic
pressure changes within the cell [9632260]. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · UniProtKB KeyWords (KW) ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 1 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Gated mechanosensitive channel domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 1 hidden Markov models representing the Gated mechanosensitive channel superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · UniProtKB KeyWords (KW) · Internal database links ]
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