SUPERFAMILY 1.75 HMM library and genome assignments server


Family A G protein-coupled receptor-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Family A G protein-coupled receptor-like [ 81322]
Superfamily:   Family A G protein-coupled receptor-like [ 81321] (2)
Families:   Bacteriorhodopsin-like [ 81319] (5)
  Rhodopsin-like [ 81320]


Superfamily statistics
Genomes (543) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 72,976 0 43
Proteins 71,935 0 43


Functional annotation
General category Regulation
Detailed category Signal transduction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus00Least InformativeDirect
Biological Process (BP)multicellular organismal process00Least InformativeDirect
Biological Process (BP)regulation of cellular process1.937e-090Least InformativeDirect
Biological Process (BP)single-organism cellular process7.871e-060Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)signal transduction00Moderately InformativeDirect
Biological Process (BP)system process00Moderately InformativeDirect
Biological Process (BP)positive regulation of response to stimulus0.0008960Moderately InformativeDirect
Biological Process (BP)regulation of localization0.83520Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.15390.0001654Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.70921Moderately InformativeInherited
Biological Process (BP)homeostatic process0.10740Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound11Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.072911Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus11Moderately InformativeInherited
Biological Process (BP)ion transport10.1856Moderately InformativeInherited
Biological Process (BP)organic substance transport10.7618Moderately InformativeInherited
Biological Process (BP)cellular localization11Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process10.01073Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus11Moderately InformativeInherited
Biological Process (BP)gene expression11Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process11Moderately InformativeInherited
Biological Process (BP)RNA metabolic process11Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.20448.528e-07Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.66870Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10Moderately InformativeInherited
Biological Process (BP)regulation of biosynthetic process0.8580.1597Moderately InformativeInherited
Biological Process (BP)response to organic substance10.000106Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus11Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process11Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process11Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process11Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process11Moderately InformativeInherited
Biological Process (BP)reproduction11Moderately InformativeInherited
Biological Process (BP)immune system process0.087770.001961Moderately InformativeInherited
Biological Process (BP)regulation of secretion7.375e-080InformativeDirect
Biological Process (BP)regulation of purine nucleotide metabolic process7.167e-070InformativeDirect
Biological Process (BP)positive regulation of signal transduction1.822e-060InformativeDirect
Biological Process (BP)regulation of intracellular protein kinase cascade5.756e-050InformativeDirect
Biological Process (BP)locomotion0.00010228.014e-11InformativeDirect
Biological Process (BP)regulation of response to external stimulus0.00013240InformativeDirect
Biological Process (BP)positive regulation of phosphate metabolic process0.00023490InformativeDirect
Biological Process (BP)response to wounding0.00035040InformativeDirect
Biological Process (BP)blood circulation0.00036760InformativeDirect
Biological Process (BP)positive regulation of nitrogen compound metabolic process0.0087187.104e-08InformativeInherited
Biological Process (BP)positive regulation of transport0.07520InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.078241.032e-08InformativeInherited
Biological Process (BP)cellular cation homeostasis0.031351.029e-11InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound0.6221InformativeInherited
Biological Process (BP)response to cytokine stimulus0.081990.01124InformativeInherited
Biological Process (BP)nitrogen compound transport10.8493InformativeInherited
Biological Process (BP)metal ion homeostasis0.011161.075e-13InformativeInherited
Biological Process (BP)single-organism behavior0.0092530.4667InformativeInherited
Biological Process (BP)secretion by cell0.8440.02111InformativeInherited
Biological Process (BP)regulation of hormone levels0.8581InformativeInherited
Biological Process (BP)cell-cell signaling11InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.0011460InformativeInherited
Biological Process (BP)regulation of system process0.033330InformativeInherited
Biological Process (BP)response to lipid10.7555InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.43640.02464InformativeInherited
Biological Process (BP)response to hormone stimulus11InformativeInherited
Biological Process (BP)response to organic cyclic compound11InformativeInherited
Biological Process (BP)transcription, DNA-dependent0.0053251InformativeInherited
Biological Process (BP)regulation of immune effector process0.14081InformativeInherited
Biological Process (BP)positive regulation of immune system process0.036291InformativeInherited
Biological Process (BP)regulation of immune response0.13911InformativeInherited
Biological Process (BP)regulation of cytokine production0.12752.295e-05InformativeInherited
Biological Process (BP)regulation of cell cycle process0.72981InformativeInherited
Biological Process (BP)negative regulation of nitrogen compound metabolic process11InformativeInherited
Biological Process (BP)negative regulation of biosynthetic process11InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.019623.215e-12InformativeInherited
Biological Process (BP)regulation of body fluid levels0.72121.115e-05InformativeInherited
Biological Process (BP)response to light stimulus0.028920.001786InformativeInherited
Biological Process (BP)localization of cell0.028317.291e-09InformativeInherited
Biological Process (BP)cellular component movement0.43811InformativeInherited
Biological Process (BP)sexual reproduction0.77021InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.83360.3798InformativeInherited
Biological Process (BP)cellular process involved in reproduction0.98611InformativeInherited
Biological Process (BP)single organism reproductive process11InformativeInherited
Biological Process (BP)defense response0.53490InformativeInherited
Biological Process (BP)regulation of response to stress0.86521InformativeInherited
Biological Process (BP)regulation of growth11InformativeInherited
Biological Process (BP)sensory perception00Highly InformativeDirect
Biological Process (BP)G-protein coupled receptor signaling pathway00Highly InformativeDirect
Biological Process (BP)detection of light stimulus4.061e-080Highly InformativeDirect
Biological Process (BP)positive regulation of MAPK cascade1.008e-070Highly InformativeDirect
Biological Process (BP)regulation of cyclic nucleotide metabolic process1.656e-070Highly InformativeDirect
Biological Process (BP)inflammatory response1.07e-060Highly InformativeDirect
Biological Process (BP)cellular calcium ion homeostasis5.603e-060Highly InformativeDirect
Biological Process (BP)regulation of blood pressure1.35e-050Highly InformativeDirect
Biological Process (BP)regulation of hormone secretion2.291e-050Highly InformativeDirect
Biological Process (BP)regulation of ERK1 and ERK2 cascade0.00056420Highly InformativeDirect
Biological Process (BP)positive regulation of protein secretion0.057080Highly InformativeInherited
Biological Process (BP)regulation of cytokine secretion0.065721.771e-05Highly InformativeInherited
Biological Process (BP)response to carbohydrate stimulus11Highly InformativeInherited
Biological Process (BP)cytokine-mediated signaling pathway0.78711Highly InformativeInherited
Biological Process (BP)response to drug11Highly InformativeInherited
Biological Process (BP)learning or memory0.74411Highly InformativeInherited
Biological Process (BP)hormone transport0.0040936.71e-12Highly InformativeInherited
Biological Process (BP)signal release0.038370.04928Highly InformativeInherited
Biological Process (BP)cellular response to steroid hormone stimulus0.012830.005259Highly InformativeInherited
Biological Process (BP)hormone-mediated signaling pathway11Highly InformativeInherited
Biological Process (BP)transcription from RNA polymerase II promoter1.966e-051Highly InformativeInherited
Biological Process (BP)positive regulation of cell activation0.64621Highly InformativeInherited
Biological Process (BP)positive regulation of cytokine production0.55061Highly InformativeInherited
Biological Process (BP)regulation of cell division0.21270.3586Highly InformativeInherited
Biological Process (BP)positive regulation of cell cycle process0.43711Highly InformativeInherited
Biological Process (BP)hemostasis0.043751Highly InformativeInherited
Biological Process (BP)coagulation0.44550.1934Highly InformativeInherited
Biological Process (BP)wound healing0.95151Highly InformativeInherited
Biological Process (BP)regulation of amine transport0.022671.175e-09Highly InformativeInherited
Biological Process (BP)cellular process involved in reproduction in multicellular organism0.24911Highly InformativeInherited
Biological Process (BP)regulation of acute inflammatory response0.061470.8066Highly InformativeInherited
Biological Process (BP)positive regulation of response to external stimulus0.093651.069e-08Highly InformativeInherited
Biological Process (BP)positive regulation of defense response0.17111Highly InformativeInherited
Biological Process (BP)activation of immune response0.0081130.5957Highly InformativeInherited
Biological Process (BP)immune response-regulating signaling pathway11Highly InformativeInherited
Biological Process (BP)regulation of multicellular organism growth0.065280.01346Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)molecular transducer activity00InformativeDirect
Molecular Function (MF)receptor activity00InformativeDirect
Molecular Function (MF)amide binding1.671e-050InformativeDirect
Molecular Function (MF)lipid binding0.34410.0004615InformativeInherited
Molecular Function (MF)odorant binding00Highly InformativeDirect
Molecular Function (MF)G-protein coupled receptor activity8.944e-070Highly InformativeDirect
Molecular Function (MF)peptide binding8.459e-060Highly InformativeDirect
Molecular Function (MF)hormone binding1.927e-050Highly InformativeDirect
Molecular Function (MF)isoprenoid binding0.21890.003818Highly InformativeInherited
Cellular Component (CC)membrane00Least InformativeDirect
Cellular Component (CC)intracellular organelle part11Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)plasma membrane00Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane00Moderately InformativeDirect
Cellular Component (CC)cell projection0.057647.113e-07Moderately InformativeInherited
Cellular Component (CC)organelle membrane11Moderately InformativeInherited
Cellular Component (CC)intrinsic to plasma membrane00InformativeDirect
Cellular Component (CC)integral to membrane1.578e-074.861e-14InformativeDirect
Cellular Component (CC)endosome0.00022693.181e-12InformativeDirect
Cellular Component (CC)cilium part3.971e-145.776e-09Highly InformativeDirect
Cellular Component (CC)early endosome2.609e-100.0006609Highly InformativeDirect
Cellular Component (CC)integral to plasma membrane2.265e-073.481e-14Highly InformativeDirect
Cellular Component (CC)cell projection membrane0.17410.8915Highly InformativeInherited
Cellular Component (CC)nonmotile primary cilium00.0018Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.8601 Least Informative Inherited
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) system process 0 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 0 Moderately Informative Direct
Biological Process (BP) homeostatic process 0 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.0001654 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 8.528e-07 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 0 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.000106 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.1597 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) ion transport 0.1856 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.01073 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.7618 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 0.001961 Moderately Informative Inherited
Biological Process (BP) organ development 0.06636 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.01111 Moderately Informative Inherited
Biological Process (BP) regulation of secretion 0 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 0 Informative Direct
Biological Process (BP) positive regulation of signal transduction 0 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 0 Informative Direct
Biological Process (BP) locomotion 8.014e-11 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0 Informative Direct
Biological Process (BP) positive regulation of phosphate metabolic process 0 Informative Direct
Biological Process (BP) response to wounding 0 Informative Direct
Biological Process (BP) blood circulation 0 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0 Informative Direct
Biological Process (BP) positive regulation of nitrogen compound metabolic process 7.104e-08 Informative Direct
Biological Process (BP) metal ion homeostasis 1.075e-13 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 3.215e-12 Informative Direct
Biological Process (BP) localization of cell 7.291e-09 Informative Direct
Biological Process (BP) cellular cation homeostasis 1.029e-11 Informative Direct
Biological Process (BP) regulation of system process 0 Informative Direct
Biological Process (BP) positive regulation of transport 0 Informative Direct
Biological Process (BP) regulation of establishment of protein localization 1.032e-08 Informative Direct
Biological Process (BP) regulation of cytokine production 2.295e-05 Informative Direct
Biological Process (BP) regulation of locomotion 1.69e-12 Informative Direct
Biological Process (BP) regulation of cellular component movement 1.809e-07 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) positive regulation of protein modification process 0.0003209 Informative Direct
Biological Process (BP) regulation of ion transport 7.428e-09 Informative Direct
Biological Process (BP) regulation of body fluid levels 1.115e-05 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 0.0005583 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 3.069e-09 Informative Direct
Biological Process (BP) regulation of lipid metabolic process 1.842e-06 Informative Direct
Biological Process (BP) regulation of nervous system development 0.08876 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.01853 Informative Inherited
Biological Process (BP) response to organonitrogen compound 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 1 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.01124 Informative Inherited
Biological Process (BP) metal ion transport 0.005908 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.1608 Informative Inherited
Biological Process (BP) growth 1 Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0.4579 Informative Inherited
Biological Process (BP) regulation of intracellular transport 1 Informative Inherited
Biological Process (BP) muscle tissue development 0.1898 Informative Inherited
Biological Process (BP) muscle structure development 1 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.3798 Informative Inherited
Biological Process (BP) regulation of kinase activity 0.1017 Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.002157 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.8493 Informative Inherited
Biological Process (BP) negative regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.4667 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.2228 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.2705 Informative Inherited
Biological Process (BP) response to organic cyclic compound 1 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.02464 Informative Inherited
Biological Process (BP) response to hormone stimulus 1 Informative Inherited
Biological Process (BP) response to lipid 0.7555 Informative Inherited
Biological Process (BP) transcription, DNA-dependent 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.3292 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) regulation of immune effector process 1 Informative Inherited
Biological Process (BP) positive regulation of immune system process 1 Informative Inherited
Biological Process (BP) regulation of immune response 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of cell cycle process 1 Informative Inherited
Biological Process (BP) anion transport 1 Informative Inherited
Biological Process (BP) organic acid transport 1 Informative Inherited
Biological Process (BP) response to nutrient levels 0.8107 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) regulation of response to stress 1 Informative Inherited
Biological Process (BP) regulation of cellular catabolic process 0.1238 Informative Inherited
Biological Process (BP) negative regulation of catalytic activity 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) lipid localization 0.4556 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) regulation of hormone levels 1 Informative Inherited
Biological Process (BP) response to other organism 0.0691 Informative Inherited
Biological Process (BP) response to light stimulus 0.001786 Informative Inherited
Biological Process (BP) secretion by cell 0.02111 Informative Inherited
Biological Process (BP) protein transport 0.7303 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 1 Informative Inherited
Biological Process (BP) sexual reproduction 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 1 Informative Inherited
Biological Process (BP) regulation of cell proliferation 1 Informative Inherited
Biological Process (BP) cardiovascular system development 0.001653 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) protein localization to organelle 1 Informative Inherited
Biological Process (BP) phosphorylation 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.9582 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.3539 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 1 Informative Inherited
Biological Process (BP) muscle system process 1 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.004501 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) immune response 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.06805 Informative Inherited
Biological Process (BP) immune effector process 0.2864 Informative Inherited
Biological Process (BP) regulation of growth 1 Informative Inherited
Biological Process (BP) transmission of nerve impulse 1 Informative Inherited
Biological Process (BP) cell-cell signaling 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) sensory perception 0 Highly Informative Direct
Biological Process (BP) G-protein coupled receptor signaling pathway 0 Highly Informative Direct
Biological Process (BP) detection of light stimulus 0 Highly Informative Direct
Biological Process (BP) positive regulation of MAPK cascade 0 Highly Informative Direct
Biological Process (BP) regulation of cyclic nucleotide metabolic process 0 Highly Informative Direct
Biological Process (BP) inflammatory response 0 Highly Informative Direct
Biological Process (BP) cellular calcium ion homeostasis 0 Highly Informative Direct
Biological Process (BP) regulation of blood pressure 0 Highly Informative Direct
Biological Process (BP) regulation of hormone secretion 0 Highly Informative Direct
Biological Process (BP) regulation of ERK1 and ERK2 cascade 0 Highly Informative Direct
Biological Process (BP) hormone transport 6.71e-12 Highly Informative Direct
Biological Process (BP) leukocyte migration 1.611e-13 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0 Highly Informative Direct
Biological Process (BP) regulation of amine transport 1.175e-09 Highly Informative Direct
Biological Process (BP) calcium ion transport 0 Highly Informative Direct
Biological Process (BP) angiogenesis 0.000276 Highly Informative Direct
Biological Process (BP) leukocyte proliferation 1.557e-08 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 4.951e-11 Highly Informative Direct
Biological Process (BP) regulation of behavior 0 Highly Informative Direct
Biological Process (BP) negative regulation of secretion 2.766e-14 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 0 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 8.342e-10 Highly Informative Direct
Biological Process (BP) negative regulation of response to external stimulus 6.463e-12 Highly Informative Direct
Biological Process (BP) regulation of phospholipase activity 0.0006937 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 1.771e-05 Highly Informative Direct
Biological Process (BP) positive regulation of response to external stimulus 1.069e-08 Highly Informative Direct
Biological Process (BP) regulation of ion homeostasis 2.183e-08 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 1.007e-05 Highly Informative Direct
Biological Process (BP) positive regulation of protein kinase activity 8.662e-05 Highly Informative Direct
Biological Process (BP) leukocyte activation involved in immune response 1.286e-10 Highly Informative Direct
Biological Process (BP) regulation of angiogenesis 8.795e-09 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 8.004e-09 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 1.749e-09 Highly Informative Direct
Biological Process (BP) digestion 2.533e-11 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 1.291e-12 Highly Informative Direct
Biological Process (BP) positive regulation of homeostatic process 0 Highly Informative Direct
Biological Process (BP) regulation of muscle contraction 0 Highly Informative Direct
Biological Process (BP) regulation of interleukin-1 beta production 0 Highly Informative Direct
Biological Process (BP) response to alkaloid 2.099e-14 Highly Informative Direct
Biological Process (BP) regulation of G-protein coupled receptor protein signaling pathway 3.624e-09 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 6.751e-08 Highly Informative Direct
Biological Process (BP) adult behavior 1.493e-07 Highly Informative Direct
Biological Process (BP) regulation of cellular amine metabolic process 1.908e-07 Highly Informative Direct
Biological Process (BP) regulation of nitric oxide biosynthetic process 1.521e-06 Highly Informative Direct
Biological Process (BP) amide transport 3.673e-05 Highly Informative Direct
Biological Process (BP) regulation of wound healing 0.0003063 Highly Informative Direct
Biological Process (BP) regulation of circadian rhythm 0.0004057 Highly Informative Direct
Biological Process (BP) regulation of hemostasis 0.0004507 Highly Informative Direct
Biological Process (BP) negative regulation of cellular catabolic process 0.0006312 Highly Informative Direct
Biological Process (BP) response to ethanol 0.0007442 Highly Informative Direct
Biological Process (BP) regulation of coagulation 0.0009047 Highly Informative Direct
Biological Process (BP) regulation of transporter activity 0.06579 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane transport 0.2411 Highly Informative Inherited
Biological Process (BP) negative regulation of protein transport 0.008531 Highly Informative Inherited
Biological Process (BP) cellular response to alcohol 0.6857 Highly Informative Inherited
Biological Process (BP) response to peptide hormone stimulus 0.4084 Highly Informative Inherited
Biological Process (BP) cellular response to peptide 0.1398 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 1 Highly Informative Inherited
Biological Process (BP) positive regulation of lipid metabolic process 0.05704 Highly Informative Inherited
Biological Process (BP) MAPK cascade 1 Highly Informative Inherited
Biological Process (BP) cytokine-mediated signaling pathway 1 Highly Informative Inherited
Biological Process (BP) regulation of reproductive process 1 Highly Informative Inherited
Biological Process (BP) regulation of multi-organism process 1 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.03722 Highly Informative Inherited
Biological Process (BP) cardiac muscle tissue development 1 Highly Informative Inherited
Biological Process (BP) tissue homeostasis 0.008756 Highly Informative Inherited
Biological Process (BP) muscle fiber development 0.004521 Highly Informative Inherited
Biological Process (BP) learning or memory 1 Highly Informative Inherited
Biological Process (BP) signal release 0.04928 Highly Informative Inherited
Biological Process (BP) placenta development 0.371 Highly Informative Inherited
Biological Process (BP) female pregnancy 0.3386 Highly Informative Inherited
Biological Process (BP) positive regulation of catabolic process 1 Highly Informative Inherited
Biological Process (BP) circadian rhythm 0.1306 Highly Informative Inherited
Biological Process (BP) response to drug 1 Highly Informative Inherited
Biological Process (BP) cellular response to steroid hormone stimulus 0.005259 Highly Informative Inherited
Biological Process (BP) hormone-mediated signaling pathway 1 Highly Informative Inherited
Biological Process (BP) transcription from RNA polymerase II promoter 1 Highly Informative Inherited
Biological Process (BP) regulation of cytokine biosynthetic process 0.1859 Highly Informative Inherited
Biological Process (BP) myeloid leukocyte activation 0.06421 Highly Informative Inherited
Biological Process (BP) positive regulation of cell activation 1 Highly Informative Inherited
Biological Process (BP) positive regulation of cytokine production 1 Highly Informative Inherited
Biological Process (BP) regulation of cell division 0.3586 Highly Informative Inherited
Biological Process (BP) positive regulation of cell cycle process 1 Highly Informative Inherited
Biological Process (BP) regulation of response to nutrient levels 1 Highly Informative Inherited
Biological Process (BP) regulation of protein complex assembly 0.1105 Highly Informative Inherited
Biological Process (BP) hemostasis 1 Highly Informative Inherited
Biological Process (BP) coagulation 0.1934 Highly Informative Inherited
Biological Process (BP) monocarboxylic acid transport 0.1168 Highly Informative Inherited
Biological Process (BP) positive regulation of intracellular transport 0.04374 Highly Informative Inherited
Biological Process (BP) phenol-containing compound metabolic process 0.08254 Highly Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 1 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.6401 Highly Informative Inherited
Biological Process (BP) small GTPase mediated signal transduction 1 Highly Informative Inherited
Biological Process (BP) protein targeting to nucleus 0.06629 Highly Informative Inherited
Biological Process (BP) nuclear import 0.07691 Highly Informative Inherited
Biological Process (BP) protein localization to nucleus 0.2153 Highly Informative Inherited
Biological Process (BP) protein import 0.3245 Highly Informative Inherited
Biological Process (BP) peptidyl-tyrosine modification 0.3774 Highly Informative Inherited
Biological Process (BP) protein phosphorylation 1 Highly Informative Inherited
Biological Process (BP) purine ribonucleotide biosynthetic process 0.1049 Highly Informative Inherited
Biological Process (BP) positive regulation of cell migration 0.07333 Highly Informative Inherited
Biological Process (BP) regulation of acute inflammatory response 0.8066 Highly Informative Inherited
Biological Process (BP) positive regulation of defense response 1 Highly Informative Inherited
Biological Process (BP) activation of immune response 0.5957 Highly Informative Inherited
Biological Process (BP) immune response-regulating signaling pathway 1 Highly Informative Inherited
Biological Process (BP) chemotaxis 1 Highly Informative Inherited
Biological Process (BP) wound healing 1 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.5611 Highly Informative Inherited
Biological Process (BP) vascular process in circulatory system 0.01213 Highly Informative Inherited
Biological Process (BP) regulation of multicellular organism growth 0.01346 Highly Informative Inherited
Biological Process (BP) regulation of synaptic transmission 0.002776 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) cation binding 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) amide binding 0 Informative Direct
Molecular Function (MF) lipid binding 0.0004615 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) receptor binding 0.3248 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 1 Informative Inherited
Molecular Function (MF) odorant binding 0 Highly Informative Direct
Molecular Function (MF) G-protein coupled receptor activity 0 Highly Informative Direct
Molecular Function (MF) peptide binding 0 Highly Informative Direct
Molecular Function (MF) hormone binding 0 Highly Informative Direct
Molecular Function (MF) steroid binding 6.353e-06 Highly Informative Direct
Molecular Function (MF) drug binding 3.729e-14 Highly Informative Direct
Molecular Function (MF) isoprenoid binding 0.003818 Highly Informative Inherited
Molecular Function (MF) calcium ion transmembrane transporter activity 0.1498 Highly Informative Inherited
Molecular Function (MF) ion gated channel activity 0.9591 Highly Informative Inherited
Molecular Function (MF) cation channel activity 1 Highly Informative Inherited
Molecular Function (MF) phosphoric diester hydrolase activity 0.04424 Highly Informative Inherited
Molecular Function (MF) lipase activity 0.1311 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 0 Moderately Informative Direct
Cellular Component (CC) cell projection 7.113e-07 Moderately Informative Direct
Cellular Component (CC) organelle membrane 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) organelle envelope 1 Moderately Informative Inherited
Cellular Component (CC) endomembrane system 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0 Informative Direct
Cellular Component (CC) integral to membrane 4.861e-14 Informative Direct
Cellular Component (CC) endosome 3.181e-12 Informative Direct
Cellular Component (CC) synapse part 1.256e-06 Informative Direct
Cellular Component (CC) neuron projection 1 Informative Inherited
Cellular Component (CC) nuclear envelope 0.06831 Informative Inherited
Cellular Component (CC) cilium part 5.776e-09 Highly Informative Direct
Cellular Component (CC) early endosome 0.0006609 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 3.481e-14 Highly Informative Direct
Cellular Component (CC) receptor complex 1.373e-13 Highly Informative Direct
Cellular Component (CC) nuclear membrane 0.0004258 Highly Informative Direct
Cellular Component (CC) cell projection membrane 0.8915 Highly Informative Inherited
Cellular Component (CC) nonmotile primary cilium 0.0018 Highly Informative Inherited
Cellular Component (CC) trans-Golgi network 0.0605 Highly Informative Inherited

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)