SUPERFAMILY 1.75 HMM library and genome assignments server


TolA/TonB C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TolA/TonB C-terminal domain [ 74652]
Superfamily:   TolA/TonB C-terminal domain [ 74653] (2)
Families:   TolA [ 55217]
  TonB [ 64326]


Superfamily statistics
Genomes (1,022) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 3,868 13,702 8
Proteins 3,808 13,459 8


Functional annotation
General category Other
Detailed category Viral proteins

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details) Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 2.003e-05 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.8286 Least Informative Inherited
Biological Process (BP) homeostatic process 5.34e-07 Moderately Informative Direct
Biological Process (BP) ion transport 0.001868 Moderately Informative Inherited
Biological Process (BP) metal ion homeostasis 1.472e-12 Informative Direct
Biological Process (BP) cellular cation homeostasis 8.582e-12 Informative Direct
Biological Process (BP) transmembrane transport 7.12e-10 Informative Direct
Biological Process (BP) cellular iron ion homeostasis 0 Highly Informative Direct
Biological Process (BP) ion transmembrane transport 4.306e-12 Highly Informative Direct
Molecular Function (MF) transporter activity 6.327e-07 Moderately Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 8.744e-11 Informative Direct
Molecular Function (MF) inorganic cation transmembrane transporter activity 4.812e-10 Informative Direct
Molecular Function (MF) transition metal ion transmembrane transporter activity 0 Highly Informative Direct
Cellular Component (CC) membrane 0.009102 Least Informative Inherited
Cellular Component (CC) intrinsic to membrane 3.291e-08 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.0002116 Moderately Informative Direct
Cellular Component (CC) external encapsulating structure 4.026e-11 Informative Direct
Cellular Component (CC) intrinsic to plasma membrane 4.628e-05 Informative Direct
Cellular Component (CC) periplasmic space 0 Highly Informative Direct
Cellular Component (CC) cell envelope 0 Highly Informative Direct
Cellular Component (CC) external encapsulating structure part 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processVirulence7.621e-09InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane1.678e-07Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainSignal-anchor0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a TolA/TonB C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the TolA/TonB C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]