SUPERFAMILY 1.75 HMM library and genome assignments server

TolA/TonB C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TolA/TonB C-terminal domain [ 74652]
Superfamily:   TolA/TonB C-terminal domain [ 74653] (2)
Families:   TolA [ 55217]
  TonB [ 64326]

Superfamily statistics
Genomes (1,309) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,881 27,942 8
Proteins 4,814 27,463 8

Functional annotation
General category Other
Detailed category Viral proteins

Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details) Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.0006463 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of biological quality 0.02601 Moderately Informative Inherited
Biological Process (BP) cation homeostasis 0.000003648 Informative Direct
Biological Process (BP) cellular chemical homeostasis 0.000002879 Informative Direct
Biological Process (BP) transition metal ion homeostasis 0.000000006305 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processVirulence0.00000001124InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0.00000008685Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a TolA/TonB C-terminal domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the TolA/TonB C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]