SUPERFAMILY 1.75 HMM library and genome assignments server

Glutamyl tRNA-reductase dimerization domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Glutamyl tRNA-reductase dimerization domain [ 69074]
Superfamily:   Glutamyl tRNA-reductase dimerization domain [ 69075]
Families:   Glutamyl tRNA-reductase dimerization domain [ 69076]


Superfamily statistics
Genomes (1,749) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,881 11,607 1
Proteins 1,881 11,607 1


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.000002449 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.000003485 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.000003871 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.000006031 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.00001108 Least Informative Direct
Biological Process (BP) cofactor metabolic process 0.00000000003145 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0.000000001773 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.000000007 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.000000007111 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.000000007135 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.00000001732 Moderately Informative Direct
Biological Process (BP) tetrapyrrole metabolic process 0.000000000000007248 Informative Direct
Biological Process (BP) porphyrin-containing compound biosynthetic process 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Glutamyl-tRNA reductase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processChlorophyll biosynthesis0Highly InformativeDirect
Biological processPorphyrin biosynthesis0Highly InformativeDirect
Molecular functionNADP0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0Least InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)porphyrin-containing compound metabolism0Moderately InformativeDirect
UniPathway (UP)pigment biosynthesis0InformativeDirect
UniPathway (UP)protoporphyrin-IX biosynthesis0InformativeDirect
UniPathway (UP)heterocycle biosynthesis0.000000000004692InformativeDirect
UniPathway (UP)chlorophyll biosynthesis0.0000005111Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR015896 SSF69075 Protein matches
Abstract

This entry represents the C-terminal domain of glutamyl-tRNA reductase , which reduces glutamyl-tRNA to glutamate-1-semialdehyde during the first stage of tetrapyrrole biosynthesis by the C5 pathway [PubMed11215515, PubMed1502723]. The enzyme requires NADPH as a cofactor.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glutamyl tRNA-reductase dimerization domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Glutamyl tRNA-reductase dimerization domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]