|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
establishment of localization |
0 |
0.7696 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism transport |
7.488e-10 |
0.8013 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of localization in cell |
0.0001144 |
1.119 |
-- |
DIRECT |
| Biological Process (BP) |
retrograde transport, endosome to Golgi |
4.008e-15 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
phagosome maturation |
7.835e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
reactive oxygen species metabolic process |
1.152e-13 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization |
1.902e-12 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
neutrophil mediated immunity |
2.632e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of smooth muscle contraction |
2.375e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte mediated cytotoxicity |
3.167e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
glycerolipid biosynthetic process |
3.229e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization to vacuole |
8.141e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
modification by host of symbiont morphology or physiology |
9.575e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
hydrogen peroxide biosynthetic process |
1.205e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
phagolysosome assembly |
1.21e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of muscle contraction |
1.615e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
myeloid leukocyte mediated immunity |
4.621e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell killing |
1.075e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
phospholipid biosynthetic process |
1.301e-07 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle contraction |
1.958e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization to vacuole |
1.321e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
receptor metabolic process |
1.444e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellularization |
2.686e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of GTPase activity |
4.088e-06 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization |
5.064e-06 |
1.42 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nucleotide catabolic process |
5.105e-06 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
membrane organization |
5.414e-06 |
1.523 |
-- |
DIRECT |
| Biological Process (BP) |
interaction with symbiont |
8.738e-06 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular transport |
9.254e-06 |
1.194 |
-- |
DIRECT |
| Biological Process (BP) |
icosanoid metabolic process |
1.045e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid derivative metabolic process |
1.045e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
vesicle fusion |
1.277e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting to vacuole |
3.404e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
vacuolar transport |
3.793e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
detection of light stimulus |
3.842e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic cell clearance |
3.924e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
defense response to fungus |
4.044e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
early endosome to late endosome transport |
6.882e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of purine nucleotide metabolic process |
8.259e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nucleotide metabolic process |
8.634e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
defense response to bacterium |
0.0001484 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catabolic process |
0.0004805 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
Golgi organization |
0.0005929 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
detection of abiotic stimulus |
0.0006551 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of GTPase activity |
0.0007648 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
lipid metabolic process |
0.0008119 |
0.9431 |
-- |
DIRECT |
| Biological Process (BP) |
endocytosis |
1 |
1.854 |
-- |
INHERITED FROM: phagosome-lysosome fusion involved in apoptotic cell clearance || apoptotic cell clearance || phagosome maturation involved in apoptotic cell clearance || phagosome-lysosome fusion || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance |
| Biological Process (BP) |
membrane fusion |
0.01057 |
2 |
-- |
INHERITED FROM: phagosome-lysosome fusion involved in apoptotic cell clearance || vesicle fusion || phagosome-lysosome fusion |
| Biological Process (BP) |
cellular macromolecule localization |
0.005327 |
1.319 |
-- |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole || protein localization to vacuole |
| Biological Process (BP) |
cellular protein localization |
0.07424 |
1.337 |
-- |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole || protein localization to vacuole |
| Biological Process (BP) |
establishment of protein localization to organelle |
0.6159 |
1.796 |
-- |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole |
| Biological Process (BP) |
biological regulation |
1 |
0.4202 |
-- |
INHERITED FROM: neutrophil mediated killing of symbiont cell || killing of cells of other organism || positive regulation of Golgi vesicle fusion to target membrane || regulation of purine nucleotide metabolic process || negative regulation of smooth muscle contraction || disruption of cells of other organism || neutrophil mediated killing of fungus || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of vesicle fusion || killing by host of symbiont cells || regulation of muscle contraction || modification of morphology or physiology of other organism || neutrophil mediated killing of gram-positive bacterium || phototransduction || negative regulation of muscle contraction || regulation of purine nucleotide catabolic process || regulation of vesicle-mediated transport || regulation of Golgi vesicle fusion to target membrane || regulation of smooth muscle contraction || regulation of nucleotide metabolic process || disruption of cells of other organism involved in symbiotic interaction || neutrophil mediated killing of bacterium || regulation of nucleotide catabolic process || regulation of catabolic process || positive regulation of transport || modification by host of symbiont morphology or physiology || regulation of vesicle fusion || disruption by host of symbiont cells || regulation of GTPase activity || small GTPase mediated signal transduction || killing of cells in other organism involved in symbiotic interaction || positive regulation of GTPase activity |
| Biological Process (BP) |
cellular component assembly |
0.4102 |
1.076 |
-- |
INHERITED FROM: organelle assembly || phagosome-lysosome fusion || phagosome-lysosome fusion involved in apoptotic cell clearance || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance |
| Biological Process (BP) |
modification of morphology or physiology of other organism involved in symbiotic interaction |
0.02173 |
2.222 |
-- |
INHERITED FROM: killing of cells in other organism involved in symbiotic interaction || neutrophil mediated killing of symbiont cell || killing by host of symbiont cells || modification by host of symbiont morphology or physiology || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || disruption of cells of other organism involved in symbiotic interaction || disruption by host of symbiont cells || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8539 |
-- |
INHERITED FROM: killing of cells in other organism involved in symbiotic interaction || neutrophil mediated killing of symbiont cell || disruption of cells of other organism || modification of morphology or physiology of other organism || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || disruption by host of symbiont cells || killing by host of symbiont cells || modification by host of symbiont morphology or physiology || killing of cells of other organism || disruption of cells of other organism involved in symbiotic interaction || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
response to biotic stimulus |
0.2985 |
1.377 |
-- |
INHERITED FROM: defense response to Gram-positive bacterium || defense response to bacterium || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || response to fungus || defense response to fungus || neutrophil mediated killing of bacterium || response to yeast |
| Biological Process (BP) |
response to stress |
1 |
0.8125 |
-- |
INHERITED FROM: defense response to Gram-positive bacterium || defense response to bacterium || inflammatory response || neutrophil mediated killing of gram-positive bacterium || respiratory burst involved in defense response || neutrophil mediated killing of fungus || cellular defense response || defense response to fungus || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
cellular biosynthetic process |
1 |
0.5498 |
-- |
INHERITED FROM: hydrogen peroxide biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
regulation of biological process |
1 |
0.4486 |
-- |
INHERITED FROM: positive regulation of Golgi vesicle fusion to target membrane || regulation of purine nucleotide metabolic process || negative regulation of smooth muscle contraction || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of vesicle fusion || regulation of muscle contraction || phototransduction || negative regulation of muscle contraction || regulation of purine nucleotide catabolic process || regulation of vesicle-mediated transport || regulation of Golgi vesicle fusion to target membrane || regulation of smooth muscle contraction || regulation of nucleotide metabolic process || regulation of nucleotide catabolic process || regulation of catabolic process || positive regulation of transport || regulation of vesicle fusion || regulation of GTPase activity || small GTPase mediated signal transduction || positive regulation of GTPase activity |
| Biological Process (BP) |
regulation of cellular localization |
0.01495 |
1.357 |
-- |
INHERITED FROM: regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
transport |
0.1529 |
0.7747 |
-- |
INHERITED FROM: intracellular transport || vesicle-mediated transport || protein transport || phagolysosome assembly || endosome to lysosome transport || phagosome-lysosome fusion || early endosome to Golgi transport || apoptotic cell clearance || phagolysosome assembly involved in apoptotic cell clearance || vesicle fusion || endosomal transport || vacuolar transport || retrograde transport, endosome to Golgi || phagosome maturation involved in apoptotic cell clearance || early endosome to late endosome transport || protein targeting to vacuole || phagosome-lysosome fusion involved in apoptotic cell clearance || single-organism transport |
| Biological Process (BP) |
organophosphate biosynthetic process |
0.001127 |
1.155 |
-- |
INHERITED FROM: glycerophospholipid biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
glycerophospholipid metabolic process |
0.002689 |
1.699 |
-- |
INHERITED FROM: glycerophospholipid biosynthetic process |
| Biological Process (BP) |
negative regulation of biological process |
1 |
0.8665 |
-- |
INHERITED FROM: negative regulation of smooth muscle contraction || negative regulation of muscle contraction |
| Biological Process (BP) |
organic substance biosynthetic process |
1 |
0.5376 |
-- |
INHERITED FROM: glycerolipid biosynthetic process || phospholipid biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
interspecies interaction between organisms |
0.001615 |
1.796 |
-- |
INHERITED FROM: symbiosis, encompassing mutualism through parasitism || killing of cells in other organism involved in symbiotic interaction || neutrophil mediated killing of symbiont cell || interaction with symbiont || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || disruption by host of symbiont cells || killing by host of symbiont cells || modification by host of symbiont morphology or physiology || disruption of cells of other organism involved in symbiotic interaction || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
regulation of phosphate metabolic process |
0.1816 |
1.284 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity || regulation of nucleotide catabolic process || regulation of purine nucleotide metabolic process || regulation of nucleotide metabolic process || regulation of purine nucleotide catabolic process |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
0.186 |
1.252 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity || regulation of nucleotide catabolic process || regulation of purine nucleotide metabolic process || regulation of nucleotide metabolic process || regulation of purine nucleotide catabolic process |
| Biological Process (BP) |
regulation of catalytic activity |
0.2761 |
1.155 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity |
| Biological Process (BP) |
regulation of GTP catabolic process |
0.6327 |
2.097 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity |
| Biological Process (BP) |
positive regulation of hydrolase activity |
0.00251 |
1.62 |
-- |
INHERITED FROM: positive regulation of GTPase activity |
| Biological Process (BP) |
positive regulation of molecular function |
0.364 |
1.222 |
-- |
INHERITED FROM: positive regulation of GTPase activity |
| Biological Process (BP) |
macromolecule metabolic process |
1 |
0.4634 |
-- |
INHERITED FROM: receptor metabolic process |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
1 |
1.027 |
-- |
INHERITED FROM: regulation of GTPase activity || regulation of nucleotide catabolic process || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || regulation of purine nucleotide metabolic process || regulation of purine nucleotide catabolic process |
| Biological Process (BP) |
response to bacterium |
0.01305 |
1.658 |
-- |
INHERITED FROM: defense response to bacterium || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of bacterium || defense response to Gram-positive bacterium |
| Biological Process (BP) |
metabolic process |
1 |
0.2411 |
-- |
INHERITED FROM: unsaturated fatty acid metabolic process || phospholipid biosynthetic process || fatty acid derivative metabolic process || reactive oxygen species metabolic process || lipid metabolic process || icosanoid metabolic process || respiratory burst involved in defense response || superoxide metabolic process || glycerophospholipid biosynthetic process || hydrogen peroxide biosynthetic process || respiratory burst || glycerolipid metabolic process || leukotriene metabolic process || glycerolipid biosynthetic process || phospholipid metabolic process || cellular lipid metabolic process || receptor metabolic process |
| Biological Process (BP) |
organic substance metabolic process |
1 |
0.2676 |
-- |
INHERITED FROM: unsaturated fatty acid metabolic process || phospholipid biosynthetic process || fatty acid derivative metabolic process || lipid metabolic process || icosanoid metabolic process || glycerophospholipid biosynthetic process || glycerolipid metabolic process || leukotriene metabolic process || glycerolipid biosynthetic process || phospholipid metabolic process || cellular lipid metabolic process || receptor metabolic process |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: unsaturated fatty acid metabolic process || phospholipid biosynthetic process || reactive oxygen species metabolic process || icosanoid metabolic process || superoxide metabolic process || glycerophospholipid biosynthetic process || hydrogen peroxide biosynthetic process || glycerolipid metabolic process || leukotriene metabolic process || glycerolipid biosynthetic process || phospholipid metabolic process || cellular lipid metabolic process || receptor metabolic process |
| Biological Process (BP) |
primary metabolic process |
1 |
0.2976 |
-- |
INHERITED FROM: unsaturated fatty acid metabolic process || phospholipid biosynthetic process || glycerophospholipid biosynthetic process || glycerolipid metabolic process || leukotriene metabolic process || glycerolipid biosynthetic process || phospholipid metabolic process || cellular lipid metabolic process || lipid metabolic process |
| Biological Process (BP) |
positive regulation of biological process |
1 |
0.8182 |
-- |
INHERITED FROM: positive regulation of vesicle fusion || positive regulation of Golgi vesicle fusion to target membrane || positive regulation of transport |
| Biological Process (BP) |
regulation of transport |
0.248 |
1.155 |
-- |
INHERITED FROM: positive regulation of vesicle fusion || regulation of vesicle fusion || regulation of vesicle-mediated transport || positive regulation of transport || regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
regulation of primary metabolic process |
1 |
0.7852 |
-- |
INHERITED FROM: regulation of nucleotide catabolic process || regulation of purine nucleotide catabolic process || regulation of GTPase activity || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || regulation of purine nucleotide metabolic process |
| Biological Process (BP) |
detection of external stimulus |
0.001506 |
1.854 |
-- |
INHERITED FROM: detection of light stimulus || phototransduction |
| Biological Process (BP) |
response to radiation |
0.5199 |
1.357 |
-- |
INHERITED FROM: detection of light stimulus || phototransduction |
| Biological Process (BP) |
detection of stimulus |
0.02158 |
1.854 |
-- |
INHERITED FROM: detection of abiotic stimulus || detection of light stimulus || phototransduction |
| Biological Process (BP) |
cell communication |
1 |
0.8477 |
-- |
INHERITED FROM: phototransduction || small GTPase mediated signal transduction |
| Biological Process (BP) |
cellular response to stimulus |
1 |
0.7645 |
-- |
INHERITED FROM: phototransduction || small GTPase mediated signal transduction |
| Biological Process (BP) |
anatomical structure development |
1 |
0.7212 |
-- |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
single-multicellular organism process |
1 |
0.6383 |
-- |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
multicellular organismal development |
1 |
0.7496 |
-- |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
signaling |
1 |
0.8416 |
-- |
INHERITED FROM: small GTPase mediated signal transduction || phototransduction |
| Biological Process (BP) |
single organism signaling |
1 |
0.8601 |
-- |
INHERITED FROM: small GTPase mediated signal transduction || phototransduction |
| Biological Process (BP) |
single-organism process |
0.09375 |
0.3316 |
-- |
INHERITED FROM: Golgi organization || vesicle organization || phagosome-lysosome fusion || apoptotic cell clearance || retrograde transport, endosome to Golgi || cellular membrane organization || establishment of localization in cell || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance || cellularization || protein targeting to vacuole || protein localization to vacuole || phagosome-lysosome fusion involved in apoptotic cell clearance || single-organism transport || gastrulation with mouth forming first || endosome to lysosome transport || phototransduction || organelle fusion || establishment of protein localization to vacuole || early endosome to late endosome transport || early endosome to Golgi transport || organelle assembly || phagosome maturation involved in apoptotic cell clearance || phagosome maturation || small GTPase mediated signal transduction || intracellular transport || cellular localization || vesicle fusion || endosomal transport || vacuolar transport |
| Biological Process (BP) |
cellular process |
0.9383 |
0.1415 |
-- |
INHERITED FROM: Golgi organization || vesicle organization || phagosome-lysosome fusion || phospholipid biosynthetic process || retrograde transport, endosome to Golgi || cellular membrane organization || establishment of localization in cell || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance || superoxide metabolic process || protein targeting to vacuole || protein localization to vacuole || phagosome-lysosome fusion involved in apoptotic cell clearance || hydrogen peroxide biosynthetic process || endosome to lysosome transport || glycerolipid metabolic process || phototransduction || glycerolipid biosynthetic process || organelle fusion || phospholipid metabolic process || establishment of protein localization to vacuole || early endosome to late endosome transport || unsaturated fatty acid metabolic process || early endosome to Golgi transport || organelle assembly || phagosome maturation involved in apoptotic cell clearance || reactive oxygen species metabolic process || phagosome maturation || icosanoid metabolic process || small GTPase mediated signal transduction || glycerophospholipid biosynthetic process || intracellular transport || leukotriene metabolic process || cellular localization || vesicle fusion || endosomal transport || vacuolar transport || cellular lipid metabolic process || receptor metabolic process |
| Biological Process (BP) |
regulation of muscle system process |
0.004085 |
2.097 |
-- |
INHERITED FROM: regulation of smooth muscle contraction || regulation of muscle contraction || negative regulation of muscle contraction || negative regulation of smooth muscle contraction |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.6421 |
-- |
INHERITED FROM: icosanoid metabolic process || unsaturated fatty acid metabolic process || leukotriene metabolic process |
| Biological Process (BP) |
carboxylic acid metabolic process |
1 |
0.8416 |
-- |
INHERITED FROM: icosanoid metabolic process || leukotriene metabolic process || unsaturated fatty acid metabolic process |
| Biological Process (BP) |
oxoacid metabolic process |
1 |
0.8297 |
-- |
INHERITED FROM: icosanoid metabolic process || leukotriene metabolic process || unsaturated fatty acid metabolic process |
| Biological Process (BP) |
organic acid metabolic process |
1 |
0.8239 |
-- |
INHERITED FROM: icosanoid metabolic process || leukotriene metabolic process || unsaturated fatty acid metabolic process |
| Biological Process (BP) |
phosphorus metabolic process |
0.7479 |
0.8013 |
-- |
INHERITED FROM: phospholipid metabolic process || glycerophospholipid biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
intracellular protein transport |
0.009163 |
1.553 |
-- |
INHERITED FROM: protein targeting to vacuole |
| Biological Process (BP) |
protein targeting |
0.3375 |
1.585 |
-- |
INHERITED FROM: protein targeting to vacuole |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: neutrophil mediated immunity || Golgi organization || apoptotic cell clearance || fatty acid derivative metabolic process || killing of cells of other organism || regulation of purine nucleotide metabolic process || negative regulation of smooth muscle contraction || response to yeast || establishment of localization in cell || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance || regulation of cellular catabolic process || regulation of nucleoside metabolic process || inflammatory response || defense response to Gram-positive bacterium || cellularization || protein targeting to vacuole || single-organism transport || gastrulation with mouth forming first || modification of morphology or physiology of other organism || glycerolipid metabolic process || organelle fusion || regulation of vesicle-mediated transport || membrane organization || phospholipid metabolic process || establishment of protein localization to vacuole || detection of abiotic stimulus || unsaturated fatty acid metabolic process || disruption of cells of other organism involved in symbiotic interaction || neutrophil mediated killing of bacterium || regulation of catabolic process || modification by host of symbiont morphology or physiology || lipid metabolic process || cellular defense response || phagosome maturation || protein transport || icosanoid metabolic process || regulation of GTPase activity || reproduction of a single-celled organism || myeloid leukocyte mediated immunity || intracellular transport || killing of cells in other organism involved in symbiotic interaction || respiratory burst || cellular localization || vacuolar transport || cellular lipid metabolic process || protein localization || defense response to bacterium || neutrophil mediated killing of symbiont cell || vesicle organization || phagosome-lysosome fusion || phospholipid biosynthetic process || positive regulation of Golgi vesicle fusion to target membrane || retrograde transport, endosome to Golgi || cellular membrane organization || disruption of cells of other organism || neutrophil mediated killing of fungus || positive regulation of vesicle fusion || defense response to fungus || killing by host of symbiont cells || superoxide metabolic process || protein localization to vacuole || phagosome-lysosome fusion involved in apoptotic cell clearance || regulation of muscle contraction || localization || neutrophil mediated killing of gram-positive bacterium || hydrogen peroxide biosynthetic process || endosome to lysosome transport || phototransduction || negative regulation of muscle contraction || glycerolipid biosynthetic process || establishment of protein localization || regulation of purine nucleotide catabolic process || cell killing || early endosome to late endosome transport || vesicle-mediated transport || regulation of Golgi vesicle fusion to target membrane || regulation of smooth muscle contraction || leukocyte mediated cytotoxicity || early endosome to Golgi transport || organelle assembly || regulation of nucleotide metabolic process || phagosome maturation involved in apoptotic cell clearance || regulation of nucleotide catabolic process || reactive oxygen species metabolic process || establishment of localization || response to fungus || positive regulation of transport || neutrophil mediated cytotoxicity || regulation of vesicle fusion || interaction with symbiont || respiratory burst involved in defense response || disruption by host of symbiont cells || small GTPase mediated signal transduction || glycerophospholipid biosynthetic process || symbiosis, encompassing mutualism through parasitism || detection of light stimulus || leukotriene metabolic process || vesicle fusion || endosomal transport || receptor metabolic process || positive regulation of GTPase activity |
| Biological Process (BP) |
cellular component organization |
0.5355 |
0.6819 |
-- |
INHERITED FROM: phagolysosome assembly || Golgi organization || vesicle organization || phagosome-lysosome fusion || phagolysosome assembly involved in apoptotic cell clearance || organelle assembly || vesicle fusion || organelle fusion || membrane organization || phagosome maturation involved in apoptotic cell clearance || phagosome-lysosome fusion involved in apoptotic cell clearance || phagosome maturation || cellular membrane organization |
| Biological Process (BP) |
embryo development |
1 |
1.301 |
-- |
INHERITED FROM: gastrulation with mouth forming first |
| Biological Process (BP) |
localization |
2.912e-13 |
0.6946 |
Least Informative |
DIRECT |
| Biological Process (BP) |
biosynthetic process |
1 |
0.52 |
Least Informative |
INHERITED FROM: hydrogen peroxide biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
regulation of cellular process |
1 |
0.5317 |
Least Informative |
INHERITED FROM: regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane || regulation of nucleotide metabolic process || regulation of purine nucleotide metabolic process || regulation of nucleotide catabolic process || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of vesicle fusion || regulation of vesicle fusion || regulation of GTPase activity || small GTPase mediated signal transduction || phototransduction || regulation of purine nucleotide catabolic process || regulation of vesicle-mediated transport || positive regulation of GTPase activity |
| Biological Process (BP) |
cellular macromolecule metabolic process |
1 |
0.4976 |
Least Informative |
INHERITED FROM: receptor metabolic process |
| Biological Process (BP) |
regulation of metabolic process |
1 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of GTPase activity || regulation of nucleotide metabolic process || regulation of purine nucleotide metabolic process || regulation of nucleotide catabolic process || regulation of catabolic process || regulation of purine nucleotide catabolic process || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity |
| Biological Process (BP) |
response to stimulus |
1 |
0.5498 |
Least Informative |
INHERITED FROM: defense response to bacterium || inflammatory response || respiratory burst involved in defense response || detection of abiotic stimulus || defense response to fungus || defense response to Gram-positive bacterium || small GTPase mediated signal transduction || neutrophil mediated killing of bacterium || response to yeast || detection of light stimulus || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || phototransduction || response to fungus || cellular defense response |
| Biological Process (BP) |
developmental process |
1 |
0.6904 |
Least Informative |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
multicellular organismal process |
1 |
0.6091 |
Least Informative |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
single-organism cellular process |
0.07487 |
0.3915 |
Least Informative |
INHERITED FROM: Golgi organization || vesicle organization || phagosome-lysosome fusion || early endosome to Golgi transport || organelle assembly || retrograde transport, endosome to Golgi || phagosome maturation involved in apoptotic cell clearance || cellular membrane organization || establishment of localization in cell || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance || phagosome maturation || small GTPase mediated signal transduction || protein targeting to vacuole || protein localization to vacuole || phagosome-lysosome fusion involved in apoptotic cell clearance || intracellular transport || endosome to lysosome transport || phototransduction || cellular localization || vesicle fusion || organelle fusion || endosomal transport || vacuolar transport || establishment of protein localization to vacuole || early endosome to late endosome transport |
| Biological Process (BP) |
single-organism metabolic process |
0.9899 |
0.5376 |
Least Informative |
INHERITED FROM: icosanoid metabolic process || respiratory burst involved in defense response || unsaturated fatty acid metabolic process || phospholipid biosynthetic process || fatty acid derivative metabolic process || glycerophospholipid biosynthetic process || respiratory burst || glycerolipid metabolic process || leukotriene metabolic process || glycerolipid biosynthetic process || phospholipid metabolic process || cellular lipid metabolic process || lipid metabolic process |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.714 |
0.6536 |
Least Informative |
INHERITED FROM: phagolysosome assembly || Golgi organization || vesicle organization || phagosome-lysosome fusion || phagolysosome assembly involved in apoptotic cell clearance || organelle assembly || vesicle fusion || organelle fusion || membrane organization || phagosome maturation involved in apoptotic cell clearance || phagosome-lysosome fusion involved in apoptotic cell clearance || phagosome maturation || cellular membrane organization |
| Biological Process (BP) |
cellular localization |
3.435e-12 |
1.027 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular lipid metabolic process |
0.0001031 |
0.9747 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
immune system process |
0.7877 |
1.076 |
Moderately Informative |
INHERITED FROM: neutrophil mediated killing of symbiont cell || neutrophil mediated immunity || neutrophil mediated killing of gram-positive bacterium || respiratory burst involved in defense response || neutrophil mediated killing of fungus || leukocyte mediated cytotoxicity || neutrophil mediated cytotoxicity || myeloid leukocyte mediated immunity || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
organelle organization |
0.2821 |
0.8996 |
Moderately Informative |
INHERITED FROM: organelle assembly || vesicle fusion || organelle fusion || phagolysosome assembly || Golgi organization || phagosome maturation involved in apoptotic cell clearance || vesicle organization || phagosome-lysosome fusion || phagosome-lysosome fusion involved in apoptotic cell clearance || phagosome maturation || phagolysosome assembly involved in apoptotic cell clearance |
| Biological Process (BP) |
cellular component biogenesis |
0.7328 |
0.983 |
Moderately Informative |
INHERITED FROM: organelle assembly || phagolysosome assembly || phagosome-lysosome fusion || phagosome-lysosome fusion involved in apoptotic cell clearance || phagolysosome assembly involved in apoptotic cell clearance |
| Biological Process (BP) |
lipid biosynthetic process |
0.005961 |
1.18 |
Moderately Informative |
INHERITED FROM: glycerophospholipid biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
multi-organism process |
0.1632 |
1.086 |
Moderately Informative |
INHERITED FROM: symbiosis, encompassing mutualism through parasitism || killing of cells in other organism involved in symbiotic interaction || defense response to bacterium || neutrophil mediated killing of symbiont cell || disruption of cells of other organism || modification of morphology or physiology of other organism || interaction with symbiont || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of fungus || disruption by host of symbiont cells || response to fungus || defense response to fungus || defense response to Gram-positive bacterium || killing by host of symbiont cells || modification by host of symbiont morphology or physiology || killing of cells of other organism || disruption of cells of other organism involved in symbiotic interaction || neutrophil mediated killing of bacterium || response to yeast |
| Biological Process (BP) |
regulation of molecular function |
0.4704 |
1.056 |
Moderately Informative |
INHERITED FROM: regulation of GTPase activity || positive regulation of GTPase activity |
| Biological Process (BP) |
regulation of cellular metabolic process |
1 |
0.7905 |
Moderately Informative |
INHERITED FROM: regulation of GTPase activity || regulation of nucleotide metabolic process || regulation of purine nucleotide metabolic process || regulation of nucleotide catabolic process || regulation of purine nucleotide catabolic process || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity |
| Biological Process (BP) |
reproduction |
1 |
1.097 |
Moderately Informative |
INHERITED FROM: reproduction of a single-celled organism |
| Biological Process (BP) |
positive regulation of cellular process |
1 |
0.9066 |
Moderately Informative |
INHERITED FROM: positive regulation of vesicle fusion || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
regulation of localization |
0.01596 |
1.066 |
Moderately Informative |
INHERITED FROM: positive regulation of vesicle fusion || regulation of vesicle fusion || regulation of Golgi vesicle fusion to target membrane || regulation of vesicle-mediated transport || positive regulation of transport || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
regulation of cellular component organization |
0.435 |
1.18 |
Moderately Informative |
INHERITED FROM: positive regulation of vesicle fusion || regulation of vesicle fusion || regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of nucleotide catabolic process || regulation of purine nucleotide catabolic process || regulation of GTPase activity || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || regulation of purine nucleotide metabolic process |
| Biological Process (BP) |
macromolecule localization |
0.00947 |
1.046 |
Moderately Informative |
INHERITED FROM: protein transport || establishment of protein localization to vacuole || protein localization || protein targeting to vacuole || protein localization to vacuole || establishment of protein localization |
| Biological Process (BP) |
organic substance transport |
0.3592 |
0.9747 |
Moderately Informative |
INHERITED FROM: protein transport || protein targeting to vacuole |
| Biological Process (BP) |
response to abiotic stimulus |
1 |
1.108 |
Moderately Informative |
INHERITED FROM: phototransduction || detection of abiotic stimulus || detection of light stimulus |
| Biological Process (BP) |
single-organism developmental process |
1 |
0.7645 |
Moderately Informative |
INHERITED FROM: cellularization || gastrulation with mouth forming first |
| Biological Process (BP) |
signal transduction |
0.8503 |
0.9914 |
Moderately Informative |
INHERITED FROM: small GTPase mediated signal transduction || phototransduction |
| Biological Process (BP) |
regulation of multicellular organismal process |
1 |
0.9666 |
Moderately Informative |
INHERITED FROM: regulation of smooth muscle contraction || negative regulation of smooth muscle contraction || regulation of muscle contraction || negative regulation of muscle contraction |
| Biological Process (BP) |
monocarboxylic acid metabolic process |
0.5401 |
1.155 |
Moderately Informative |
INHERITED FROM: leukotriene metabolic process || unsaturated fatty acid metabolic process |
| Biological Process (BP) |
organophosphate metabolic process |
0.02264 |
0.9914 |
Moderately Informative |
INHERITED FROM: phospholipid metabolic process || glycerophospholipid biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
phosphate-containing compound metabolic process |
0.6794 |
0.8182 |
Moderately Informative |
INHERITED FROM: phospholipid metabolic process || glycerophospholipid biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
anatomical structure morphogenesis |
1 |
1.036 |
Moderately Informative |
INHERITED FROM: gastrulation with mouth forming first || cellularization |
| Biological Process (BP) |
vesicle-mediated transport |
0 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
protein transport |
2.155e-10 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
phospholipid metabolic process |
7.363e-08 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular membrane organization |
1.541e-05 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
glycerolipid metabolic process |
0.0001953 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transport |
0.000531 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular catabolic process |
0.0006037 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
protein localization to organelle |
1 |
1.523 |
Informative |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole || protein localization to vacuole |
| Biological Process (BP) |
response to other organism |
0.4691 |
1.398 |
Informative |
INHERITED FROM: neutrophil mediated killing of fungus || defense response to Gram-positive bacterium || defense response to bacterium || response to fungus || defense response to fungus || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of bacterium || response to yeast |
| Biological Process (BP) |
regulation of intracellular transport |
0.05871 |
1.585 |
Informative |
INHERITED FROM: regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
cytoplasmic transport |
1 |
1.337 |
Informative |
INHERITED FROM: early endosome to late endosome transport || endosome to lysosome transport || protein targeting to vacuole || early endosome to Golgi transport |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.158 |
1.337 |
Informative |
INHERITED FROM: positive regulation of GTPase activity |
| Biological Process (BP) |
regulation of hydrolase activity |
0.008551 |
1.42 |
Informative |
INHERITED FROM: regulation of GTPase activity || positive regulation of GTPase activity |
| Biological Process (BP) |
positive regulation of cellular component organization |
0.003214 |
1.699 |
Informative |
INHERITED FROM: positive regulation of vesicle fusion || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
regulation of organelle organization |
0.6305 |
1.495 |
Informative |
INHERITED FROM: positive regulation of vesicle fusion || regulation of vesicle fusion || regulation of Golgi vesicle fusion to target membrane || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
response to light stimulus |
0.3237 |
1.42 |
Informative |
INHERITED FROM: detection of light stimulus || phototransduction |
| Biological Process (BP) |
response to external stimulus |
0.9055 |
1.319 |
Informative |
INHERITED FROM: phototransduction || detection of light stimulus |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
0.2995 |
1.444 |
Informative |
INHERITED FROM: cellularization |
| Biological Process (BP) |
intracellular signal transduction |
0.2729 |
1.398 |
Informative |
INHERITED FROM: small GTPase mediated signal transduction |
| Biological Process (BP) |
response to wounding |
0.2227 |
1.495 |
Informative |
INHERITED FROM: inflammatory response |
| Biological Process (BP) |
regulation of system process |
0.00473 |
1.553 |
Informative |
INHERITED FROM: regulation of muscle contraction || negative regulation of muscle contraction || regulation of smooth muscle contraction || negative regulation of smooth muscle contraction |
| Biological Process (BP) |
fatty acid metabolic process |
0.5508 |
1.42 |
Informative |
INHERITED FROM: leukotriene metabolic process || unsaturated fatty acid metabolic process |
| Biological Process (BP) |
defense response |
0.09668 |
1.357 |
Informative |
INHERITED FROM: respiratory burst involved in defense response || neutrophil mediated killing of fungus || defense response to Gram-positive bacterium || defense response to fungus || defense response to bacterium || inflammatory response || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated killing of bacterium || cellular defense response |
| Biological Process (BP) |
immune effector process |
0.02161 |
1.658 |
Informative |
INHERITED FROM: respiratory burst involved in defense response || neutrophil mediated killing of fungus || neutrophil mediated immunity || myeloid leukocyte mediated immunity || neutrophil mediated killing of gram-positive bacterium || leukocyte mediated cytotoxicity || neutrophil mediated killing of symbiont cell || neutrophil mediated cytotoxicity || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
embryonic morphogenesis |
0.3154 |
1.62 |
Informative |
INHERITED FROM: gastrulation with mouth forming first |
| Biological Process (BP) |
endosomal transport |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
defense response to Gram-positive bacterium |
2.597e-10 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
vesicle organization |
4.335e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
organelle fusion |
1.935e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
superoxide metabolic process |
6.297e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of purine nucleotide catabolic process |
5.05e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of nucleoside metabolic process |
7.618e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
phototransduction |
1.333e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
organelle assembly |
3.424e-05 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of muscle contraction |
3.515e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
unsaturated fatty acid metabolic process |
4.894e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
glycerophospholipid biosynthetic process |
8.767e-05 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
small GTPase mediated signal transduction |
0.0001862 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to fungus |
0.0002252 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
modification of morphology or physiology of other organism |
0.0002269 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
0.0002813 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
symbiosis, encompassing mutualism through parasitism |
0.0008803 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
inflammatory response |
0.0009123 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
phagocytosis |
0.004653 |
2 |
Highly Informative |
INHERITED FROM: phagosome-lysosome fusion involved in apoptotic cell clearance || apoptotic cell clearance || phagosome maturation involved in apoptotic cell clearance || phagosome-lysosome fusion || phagolysosome assembly || phagolysosome assembly involved in apoptotic cell clearance |
| Biological Process (BP) |
cellular membrane fusion |
0.005815 |
2 |
Highly Informative |
INHERITED FROM: phagosome-lysosome fusion involved in apoptotic cell clearance || vesicle fusion || phagosome-lysosome fusion |
| Biological Process (BP) |
hydrogen peroxide metabolic process |
1 |
2.097 |
Highly Informative |
INHERITED FROM: hydrogen peroxide biosynthetic process |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
0.03321 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of muscle contraction || negative regulation of smooth muscle contraction |
| Biological Process (BP) |
Golgi vesicle transport |
0.00698 |
1.854 |
Highly Informative |
INHERITED FROM: early endosome to Golgi transport |
| Biological Process (BP) |
positive regulation of organelle organization |
0.073 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of vesicle fusion || positive regulation of Golgi vesicle fusion to target membrane |
| Biological Process (BP) |
leukocyte mediated immunity |
0.005192 |
1.921 |
Highly Informative |
INHERITED FROM: myeloid leukocyte mediated immunity || neutrophil mediated killing of fungus || neutrophil mediated killing of gram-positive bacterium || neutrophil mediated immunity || leukocyte mediated cytotoxicity || neutrophil mediated killing of symbiont cell || neutrophil mediated cytotoxicity || neutrophil mediated killing of bacterium |
| Biological Process (BP) |
gastrulation |
0.001126 |
2.222 |
Highly Informative |
INHERITED FROM: gastrulation with mouth forming first |
| Molecular Function (MF) |
phospholipid binding |
0 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
ion binding |
0 |
0.8334 |
-- |
DIRECT |
| Molecular Function (MF) |
lipase activity |
5.648e-10 |
1.9 |
-- |
DIRECT |
| Molecular Function (MF) |
protein self-association |
9.568e-09 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
phosphatidylinositol-3-phosphate binding |
1.888e-06 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
GTPase binding |
5.32e-05 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
oxidoreductase activity, acting on NAD(P)H |
7.285e-05 |
1.9 |
-- |
DIRECT |
| Molecular Function (MF) |
catalytic activity |
1 |
0.2686 |
-- |
INHERITED FROM: oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor || phosphatidylinositol 3-kinase activity || phospholipase D activity || phosphatidylinositol kinase activity || phosphoric diester hydrolase activity || phosphatidylinositol phosphate kinase activity || oxidoreductase activity, acting on NAD(P)H || lipase activity || phosphoric ester hydrolase activity || superoxide-generating NADPH oxidase activity || phospholipase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
molecular_function |
0.9384 |
0 |
-- |
INHERITED FROM: phosphatidylinositol 3-kinase activity || enzyme activator activity || phospholipase D activity || phosphatidylinositol binding || anion binding || phosphatidylinositol kinase activity || GTPase binding || lipase activity || protein self-association || phosphoric ester hydrolase activity || superoxide-generating NADPH oxidase activity || oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor || lipid binding || ion binding || phospholipid binding || phosphoric diester hydrolase activity || phosphatidylinositol-3-phosphate binding || phosphatidylinositol phosphate kinase activity || oxidoreductase activity, acting on NAD(P)H || binding || phospholipase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
phosphatidylinositol phosphate binding |
1 |
2.679 |
-- |
INHERITED FROM: phosphatidylinositol-3-phosphate binding |
| Molecular Function (MF) |
binding |
1.89e-05 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity |
0.7813 |
0.7491 |
Least Informative |
INHERITED FROM: phosphatidylinositol 3-kinase activity || phosphatidylinositol phosphate kinase activity || phosphatidylinositol kinase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
hydrolase activity |
1 |
0.6657 |
Least Informative |
INHERITED FROM: phosphoric diester hydrolase activity || phosphoric ester hydrolase activity || phospholipase D activity || phospholipase activity || lipase activity |
| Molecular Function (MF) |
anion binding |
0 |
1.076 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring phosphorus-containing groups |
0.02471 |
1.134 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol kinase activity || phosphatidylinositol 3-kinase activity || phosphatidylinositol phosphate kinase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
protein binding |
0.5429 |
0.77 |
Moderately Informative |
INHERITED FROM: GTPase binding || protein self-association |
| Molecular Function (MF) |
oxidoreductase activity |
1 |
0.9883 |
Moderately Informative |
INHERITED FROM: oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor || superoxide-generating NADPH oxidase activity || oxidoreductase activity, acting on NAD(P)H |
| Molecular Function (MF) |
hydrolase activity, acting on ester bonds |
0.09894 |
1.122 |
Moderately Informative |
INHERITED FROM: phosphoric diester hydrolase activity || phosphoric ester hydrolase activity || lipase activity || phospholipase D activity || phospholipase activity |
| Molecular Function (MF) |
enzyme regulator activity |
0.1035 |
1.134 |
Moderately Informative |
INHERITED FROM: enzyme activator activity |
| Molecular Function (MF) |
lipid binding |
0 |
1.377 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme activator activity |
0.0007592 |
1.679 |
Informative |
DIRECT |
| Molecular Function (MF) |
phosphoric ester hydrolase activity |
0.0008058 |
1.502 |
Informative |
DIRECT |
| Molecular Function (MF) |
phosphotransferase activity, alcohol group as acceptor |
0.009052 |
1.599 |
Informative |
INHERITED FROM: phosphatidylinositol kinase activity || phosphatidylinositol phosphate kinase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
kinase activity |
0.004464 |
1.474 |
Informative |
INHERITED FROM: phosphatidylinositol kinase activity || phosphatidylinositol phosphate kinase activity || phosphatidylinositol 3-kinase activity || 1-phosphatidylinositol-4-phosphate 3-kinase activity |
| Molecular Function (MF) |
enzyme binding |
0.1536 |
1.679 |
Informative |
INHERITED FROM: GTPase binding |
| Molecular Function (MF) |
phospholipase activity |
1.146e-11 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
phosphoric diester hydrolase activity |
5.41e-11 |
2.201 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
phosphatidylinositol binding |
6.885e-10 |
1.98 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
intracellular part |
1.455e-05 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
2.94e-05 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1.614e-15 |
0.2515 |
-- |
DIRECT |
| Cellular Component (CC) |
cellular_component |
3.764e-10 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
endosome membrane |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
extrinsic to membrane |
6.001e-12 |
1.843 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasmic vesicle |
7.447e-11 |
1.18 |
-- |
DIRECT |
| Cellular Component (CC) |
podosome |
3.69e-09 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasmic membrane-bounded vesicle |
7.598e-09 |
1.241 |
-- |
DIRECT |
| Cellular Component (CC) |
extrinsic to internal side of plasma membrane |
2.472e-07 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
site of polarized growth |
0.0007063 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
0.3769 |
0.3713 |
-- |
INHERITED FROM: extrinsic to organelle membrane || organelle membrane || podosome || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
macromolecular complex |
1 |
0.4276 |
-- |
INHERITED FROM: retromer complex || NADPH oxidase complex || podosome |
| Cellular Component (CC) |
cell part |
0.1712 |
0.08068 |
-- |
INHERITED FROM: retromer complex || endosome || extrinsic to organelle membrane || cytoplasmic vesicle || cytoplasm || NADPH oxidase complex || podosome || endosomal part || site of polarized growth || internal side of plasma membrane || extrinsic to internal side of plasma membrane || extrinsic to plasma membrane || cytoplasmic membrane-bounded vesicle || endomembrane system || cytoplasmic part || intracellular part || intracellular || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
cell |
0.1733 |
0.08068 |
-- |
INHERITED FROM: retromer complex || endosome || extrinsic to organelle membrane || cytoplasmic vesicle || cytoplasm || NADPH oxidase complex || podosome || endosomal part || site of polarized growth || internal side of plasma membrane || extrinsic to internal side of plasma membrane || extrinsic to plasma membrane || cytoplasmic membrane-bounded vesicle || endomembrane system || cytoplasmic part || intracellular part || intracellular || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
plasma membrane part |
0.3894 |
1.036 |
-- |
INHERITED FROM: extrinsic to plasma membrane || extrinsic to internal side of plasma membrane || internal side of plasma membrane || NADPH oxidase complex |
| Cellular Component (CC) |
cell periphery |
1 |
0.8256 |
-- |
INHERITED FROM: extrinsic to plasma membrane || extrinsic to internal side of plasma membrane || internal side of plasma membrane || NADPH oxidase complex |
| Cellular Component (CC) |
membrane part |
0.002662 |
0.6842 |
-- |
INHERITED FROM: extrinsic to plasma membrane || retromer complex || internal side of plasma membrane || extrinsic to internal side of plasma membrane || extrinsic to organelle membrane || extrinsic to endosome membrane || extrinsic to membrane || NADPH oxidase complex |
| Cellular Component (CC) |
organelle |
0.002714 |
0.1836 |
-- |
INHERITED FROM: cytoplasmic membrane-bounded vesicle || endosome || vesicle || extrinsic to organelle membrane || cytoplasmic vesicle || organelle membrane || podosome || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
intracellular organelle |
0.7556 |
0.1875 |
-- |
INHERITED FROM: cytoplasmic membrane-bounded vesicle || endosome || extrinsic to organelle membrane || cytoplasmic vesicle || podosome || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
membrane-bounded organelle |
0.9743 |
0.2912 |
-- |
INHERITED FROM: cytoplasmic membrane-bounded vesicle || endosome || extrinsic to organelle membrane || organelle membrane || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
membrane-bounded vesicle |
1 |
1.219 |
-- |
INHERITED FROM: cytoplasmic membrane-bounded vesicle |
| Cellular Component (CC) |
cytoskeletal part |
0.2539 |
1.127 |
-- |
INHERITED FROM: podosome |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6225 |
-- |
INHERITED FROM: podosome |
| Cellular Component (CC) |
cytoplasmic part |
1.922e-11 |
0.2605 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
membrane |
5.714e-05 |
0.5731 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle part |
0.9341 |
0.3893 |
Least Informative |
INHERITED FROM: extrinsic to organelle membrane || podosome || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
protein complex |
0.2866 |
0.5639 |
Least Informative |
INHERITED FROM: retromer complex || NADPH oxidase complex || podosome |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0.5525 |
0.2961 |
Least Informative |
INHERITED FROM: cytoplasmic membrane-bounded vesicle || endosome || endosomal part || extrinsic to endosome membrane || endosome membrane |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6225 |
Least Informative |
INHERITED FROM: podosome |
| Cellular Component (CC) |
organelle membrane |
3.129e-15 |
0.8514 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
vesicle |
2.931e-13 |
1.144 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
endomembrane system |
0.0009581 |
1.11 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intrinsic to membrane |
1 |
1.18 |
Moderately Informative |
INHERITED FROM: NADPH oxidase complex |
| Cellular Component (CC) |
plasma membrane |
0.8784 |
0.9734 |
Moderately Informative |
INHERITED FROM: extrinsic to plasma membrane || extrinsic to internal side of plasma membrane || internal side of plasma membrane || NADPH oxidase complex |
| Cellular Component (CC) |
cytoskeleton |
0.145 |
1.036 |
Moderately Informative |
INHERITED FROM: podosome |
| Cellular Component (CC) |
endosome |
0 |
1.462 |
Informative |
DIRECT |
| Cellular Component (CC) |
intrinsic to plasma membrane |
0.7522 |
1.696 |
Informative |
INHERITED FROM: NADPH oxidase complex |
| Cellular Component (CC) |
integral to membrane |
1 |
1.286 |
Informative |
INHERITED FROM: NADPH oxidase complex |
| Cellular Component (CC) |
actin cytoskeleton |
0.2656 |
1.428 |
Informative |
INHERITED FROM: podosome |
| Cellular Component (CC) |
endosomal part |
0 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
internal side of plasma membrane |
2.321e-06 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
extrinsic to plasma membrane |
5.972e-05 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
integral to plasma membrane |
0.5862 |
2.064 |
Highly Informative |
INHERITED FROM: NADPH oxidase complex |