SUPERFAMILY 1.73 HMM library and genome assignments server


SurE-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   SurE-like [ 64166]
  3 layers: a/b/a; mixed beta-sheet of 9 strands, order 342156798; strands 3, 8 and 9 are antiparallel to the rest; left-handed crossover connection between strands 6 and 7
Superfamily:   SurE-like [ 64167]
Families:   SurE-like [ 64168] (2)


Superfamily statistics
Genomes (751) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 956 1,021 2
Proteins 956 1,020 2


Functional annotation
General category Other
Detailed category Unknown function

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR002828 SSF64167 Protein matches
Abstract

Members of this family are acid phosphatases, [PubMed1423722]. Members include proteins from the yeast Yarrowia lipolytica, eubacterium Thermotoga maritama and crenarchaeon Pyrobactulum aerophilum. In bacteria they may be involved in the stress response [PubMed11709173]. Escherichia coli cells with the surE gene disrupted are found to survive poorly in stationary phase. In this organism, surE is next to pcm, an L-isoaspartyl protein repair methyltransferase that is also required for stationary phase survival [PubMed7928962].


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a SurE-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the SurE-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]