SUPERFAMILY 1.75 HMM library and genome assignments server

Undecaprenyl diphosphate synthase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Undecaprenyl diphosphate synthase [ 64004]
Superfamily:   Undecaprenyl diphosphate synthase [ 64005]
Families:   Undecaprenyl diphosphate synthase [ 64006]


Superfamily statistics
Genomes (3,110) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,716 19,480 2
Proteins 4,613 19,365 2


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.088820.0001073Least InformativeInherited
Biological Process (BP)single-organism cellular process0.12060.08594Least InformativeInherited
Biological Process (BP)biosynthetic process0.017340.00000005965Least InformativeInherited
Biological Process (BP)lipid metabolic process0.00019450.000000000002159Moderately InformativeDirect
Biological Process (BP)organic hydroxy compound metabolic process0.0000062280.0000000000007822Moderately InformativeDirect
Biological Process (BP)small molecule biosynthetic process0.0028040.00000002033Moderately InformativeInherited
Biological Process (BP)alcohol metabolic process0.00000020880.0000000000007455InformativeDirect
Biological Process (BP)isoprenoid metabolic process0.000000032190.0000000001345InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process0.000012170.000000000003019InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process0.00000051480Highly InformativeDirect
Molecular Function (MF)transferase activity0.0000000450.000000003231Least InformativeDirect
Molecular Function (MF)transferase activity, transferring alkyl or aryl (other than methyl) groups00InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.00000005965 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.0001073 Least Informative Direct
Biological Process (BP) protein metabolic process 0.9448 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.08594 Least Informative Inherited
Biological Process (BP) lipid metabolic process 0.000000000002159 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.00000002033 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.0000000000007822 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.002824 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.01151 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.04216 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.02375 Moderately Informative Inherited
Biological Process (BP) alcohol metabolic process 0.0000000000007455 Informative Direct
Biological Process (BP) isoprenoid metabolic process 0.0000000001345 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.000000000003019 Informative Direct
Biological Process (BP) protein glycosylation 0.00000002355 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0 Highly Informative Direct
Molecular Function (MF) transferase activity 0.000000003231 Least Informative Direct
Molecular Function (MF) transferase activity, transferring alkyl or aryl (other than methyl) groups 0 Informative Direct
Molecular Function (MF) prenyltransferase activity 0.00002845 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.9847 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.3286 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.00001724 Moderately Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited

Document: EC annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell shape0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Cellular componentEndoplasmic reticulum0.0000007115Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.0000000000003063Least InformativeDirect
UniPathway (UP)protein glycosylation0InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR001441 SSF64005 Protein matches
Abstract

Synonym(s): Di-trans-poly-cis-undecaprenyl-diphosphate synthase, Undecaprenyl pyrophosphate synthetase, Undecaprenyl pyrophosphate synthase, UPP synthetase

Di-trans-poly-cis-decaprenylcistransferase (UPP synthetase) generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) [PubMed9882662]. This bacterial enzyme is also found in archaebacteria and in a number of uncharacterised proteins including some from yeasts.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Undecaprenyl diphosphate synthase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Undecaprenyl diphosphate synthase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]