SUPERFAMILY 1.75 HMM library and genome assignments server


BAG domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Spectrin repeat-like [ 46965] (16)
Superfamily:   BAG domain [ 63491]
Families:   BAG domain [ 63492] (4)


Superfamily statistics
Genomes (446) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,639 1,504 7
Proteins 1,449 1,295 7


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 4.313e-05 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0007091 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0007576 Least Informative Direct
Biological Process (BP) developmental process 0.05402 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.4567 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.003556 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.104 Least Informative Inherited
Biological Process (BP) regulation of programmed cell death 1.525e-11 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 6.169e-06 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.005423 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.0206 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.013 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.1279 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) apoptotic process 5.218e-05 Informative Direct
Biological Process (BP) negative regulation of protein metabolic process 0.0005364 Informative Direct
Biological Process (BP) negative regulation of cell death 3.137e-05 Informative Direct
Biological Process (BP) protein folding 9.075e-07 Highly Informative Direct
Biological Process (BP) negative regulation of protein modification process 0.000253 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 8.559e-07 Highly Informative Direct
Biological Process (BP) cell fate commitment 0.0006952 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.001016 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.0268 Least Informative Inherited
Cellular Component (CC) contractile fiber part 8.768e-09 Informative Direct
Cellular Component (CC) sarcomere 7.345e-12 Highly Informative Direct

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0Least InformativeDirect

Document: MP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)gamete0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processApoptosis8.503e-11Moderately InformativeDirect
DomainRepeat0.0006076Least InformativeDirect
Post-translational modificationChaperone0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a BAG domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the BAG domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]