SUPERFAMILY 1.75 HMM library and genome assignments server


RNA polymerase subunits superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Rubredoxin-like [ 57769] (17)
Superfamily:   RNA polymerase subunits [ 63393] (2)
Families:   RBP12 subunit of RNA polymerase II [ 64576]
  RpoE2-like [ 111454]


Superfamily statistics
Genomes (581) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 1,247 1,318 2
Proteins 1,245 1,317 2


Functional annotation
General category Information
Detailed category DNA replication/repair

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process2.558e-061.624e-05Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process3.206e-058.863e-05Least InformativeDirect
Biological Process (BP)biosynthetic process8.723e-061e-05Least InformativeDirect
Biological Process (BP)cellular macromolecule metabolic process1.721e-050.00063Least InformativeDirect
Biological Process (BP)heterocycle metabolic process2.219e-061.262e-05Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process6.834e-063.269e-05Least InformativeDirect
Biological Process (BP)regulation of cellular process0.010350.2288Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.00020750.02022Least InformativeInherited
Biological Process (BP)gene expression9.255e-111.088e-08Moderately InformativeDirect
Biological Process (BP)RNA metabolic process5.969e-123.278e-09Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process8.819e-111.872e-10Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process2.268e-112.028e-10Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process4.464e-113.369e-09Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process1.309e-102.91e-10Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process3.445e-101.08e-09Moderately InformativeDirect
Biological Process (BP)regulation of cellular metabolic process3.527e-050.009537Moderately InformativeInherited
Biological Process (BP)regulation of nitrogen compound metabolic process1.753e-060.002067Moderately InformativeInherited
Biological Process (BP)regulation of biosynthetic process1.282e-060.001646Moderately InformativeInherited
Biological Process (BP)regulation of gene expression1.847e-060.002178Moderately InformativeInherited
Biological Process (BP)transcription, DNA-dependent01.896e-14InformativeDirect
Biological Process (BP)transcription from RNA polymerase II promoter00Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle1.518e-060.00014Least InformativeDirect
Cellular Component (CC)protein complex3.071e-118.519e-09Least InformativeDirect
Cellular Component (CC)intracellular organelle part3.586e-072.487e-06Least InformativeDirect
Cellular Component (CC)nuclear part1.504e-091.348e-07Moderately InformativeDirect
Cellular Component (CC)intracellular organelle lumen04.844e-12Moderately InformativeDirect
Cellular Component (CC)DNA-directed RNA polymerase complex1.914e-105.31e-10InformativeDirect
Cellular Component (CC)nucleoplasm part9.819e-091.784e-07InformativeDirect
Cellular Component (CC)transcription elongation factor complex03.129e-15Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 1.624e-05 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 8.863e-05 Least Informative Direct
Biological Process (BP) biosynthetic process 1e-05 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.00063 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 1.262e-05 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 3.269e-05 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.2288 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.02022 Least Informative Inherited
Biological Process (BP) gene expression 1.088e-08 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 3.278e-09 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 1.872e-10 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 2.028e-10 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 3.369e-09 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 2.91e-10 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 1.08e-09 Moderately Informative Direct
Biological Process (BP) regulation of cellular metabolic process 0.009537 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 0.002067 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.001646 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.002178 Moderately Informative Inherited
Biological Process (BP) transcription, DNA-dependent 1.896e-14 Informative Direct
Biological Process (BP) transcription from RNA polymerase II promoter 0 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.00014 Least Informative Direct
Cellular Component (CC) protein complex 8.519e-09 Least Informative Direct
Cellular Component (CC) intracellular organelle part 2.487e-06 Least Informative Direct
Cellular Component (CC) nuclear part 1.348e-07 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 4.844e-12 Moderately Informative Direct
Cellular Component (CC) DNA-directed RNA polymerase complex 5.31e-10 Informative Direct
Cellular Component (CC) nucleoplasm part 1.784e-07 Informative Direct
Cellular Component (CC) DNA-directed RNA polymerase II, core complex 8.211e-06 Highly Informative Direct
Cellular Component (CC) transcription elongation factor complex 3.129e-15 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)DNA-directed RNA polymerase0InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)DNA-directed RNA polymerase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA-directed RNA polymerase3.411e-11Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentChromosome0InformativeDirect
Cellular componentCentromere0Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionZinc-finger0Moderately InformativeDirect
Post-translational modificationTransferase5.424e-06Least InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationActivator1.547e-10Moderately InformativeDirect
Post-translational modificationRepressor3.673e-10Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a RNA polymerase subunits domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the RNA polymerase subunits superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]