SUPERFAMILY 1.75 HMM library and genome assignments server


Growth factor receptor domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Knottins (small inhibitors, toxins, lectins) [ 57015] (19)
Superfamily:   Growth factor receptor domain [ 57184]
Families:   Growth factor receptor domain [ 57185] (8)


Superfamily statistics
Genomes (356) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 39,781 43,726 28
Proteins 18,912 21,271 21


Functional annotation
General category Regulation
Detailed category Signal transduction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process1.317e-060Least InformativeDirect
Biological Process (BP)multicellular organismal process3.403e-060Least InformativeDirect
Biological Process (BP)localization0.0026975.5e-13Least InformativeInherited
Biological Process (BP)single-organism cellular process0.049580Least InformativeInherited
Biological Process (BP)regulation of cellular process0.0062790.02639Least InformativeInherited
Biological Process (BP)response to stimulus0.013050Least InformativeInherited
Biological Process (BP)single-organism developmental process3.692e-070Moderately InformativeDirect
Biological Process (BP)signal transduction0.00019390Moderately InformativeDirect
Biological Process (BP)enzyme linked receptor protein signaling pathway4.627e-080InformativeDirect
Biological Process (BP)localization of cell3.608e-070InformativeDirect
Biological Process (BP)locomotion1.575e-060InformativeDirect
Biological Process (BP)cellular component movement8.543e-050InformativeDirect
Biological Process (BP)transmembrane receptor protein tyrosine kinase signaling pathway1.187e-086.598e-06Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) localization 5.5e-13 Least Informative Direct
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.02639 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.003102 Least Informative Inherited
Biological Process (BP) single-organism developmental process 0 Moderately Informative Direct
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) nervous system development 7.487e-06 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 4.512e-11 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 1.083e-14 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 6.059e-14 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 4.67e-11 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 1.366e-09 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 2.697e-09 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 1.231e-06 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 4.65e-06 Moderately Informative Direct
Biological Process (BP) immune system process 0.0001352 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.0002418 Moderately Informative Direct
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.05058 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.8626 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.1876 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.3329 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.001307 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.01417 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 0.1841 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.5211 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.04932 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.6552 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.01075 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.6363 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.4683 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.6111 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.3123 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.317 Moderately Informative Inherited
Biological Process (BP) reproduction 0.01983 Moderately Informative Inherited
Biological Process (BP) tissue development 0.008501 Moderately Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 0 Informative Direct
Biological Process (BP) localization of cell 0 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) phosphorylation 0 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) response to wounding 9.864e-14 Informative Direct
Biological Process (BP) regulation of cell proliferation 1.111e-13 Informative Direct
Biological Process (BP) negative regulation of developmental process 6.808e-11 Informative Direct
Biological Process (BP) regulation of apoptotic process 1.386e-10 Informative Direct
Biological Process (BP) positive regulation of developmental process 8.205e-10 Informative Direct
Biological Process (BP) cellular component morphogenesis 2.706e-09 Informative Direct
Biological Process (BP) positive regulation of cellular component organization 4.215e-09 Informative Direct
Biological Process (BP) protein oligomerization 2.478e-08 Informative Direct
Biological Process (BP) vesicle-mediated transport 1.294e-07 Informative Direct
Biological Process (BP) growth 5.753e-07 Informative Direct
Biological Process (BP) cardiovascular system development 1.116e-06 Informative Direct
Biological Process (BP) regulation of protein phosphorylation 1.277e-06 Informative Direct
Biological Process (BP) organ morphogenesis 3.623e-06 Informative Direct
Biological Process (BP) central nervous system development 3.88e-06 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 1.915e-05 Informative Direct
Biological Process (BP) tube development 2.446e-05 Informative Direct
Biological Process (BP) tissue morphogenesis 4.029e-05 Informative Direct
Biological Process (BP) negative regulation of signaling 7.898e-05 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0.0002072 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.0002343 Informative Direct
Biological Process (BP) generation of neurons 0.0004082 Informative Direct
Biological Process (BP) negative regulation of cell communication 0.0004406 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.000818 Informative Direct
Biological Process (BP) regulation of system process 1 Informative Inherited
Biological Process (BP) negative regulation of cell death 0.2702 Informative Inherited
Biological Process (BP) cellular membrane organization 0.08519 Informative Inherited
Biological Process (BP) protein transport 0.00254 Informative Inherited
Biological Process (BP) muscle structure development 0.6524 Informative Inherited
Biological Process (BP) muscle tissue development 1 Informative Inherited
Biological Process (BP) cellular chemical homeostasis 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.07565 Informative Inherited
Biological Process (BP) regulation of growth 0.002617 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.3042 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 0.00814 Informative Inherited
Biological Process (BP) synaptic transmission 1 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.1496 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.02703 Informative Inherited
Biological Process (BP) negative regulation of transport 0.007718 Informative Inherited
Biological Process (BP) regulation of secretion 0.1415 Informative Inherited
Biological Process (BP) sensory organ development 0.01531 Informative Inherited
Biological Process (BP) embryonic organ development 0.04701 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.1408 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) secretion by cell 0.02316 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.00336 Informative Inherited
Biological Process (BP) positive regulation of transport 0.4417 Informative Inherited
Biological Process (BP) regulation of intracellular protein kinase cascade 0.07938 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.8089 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.5092 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.8634 Informative Inherited
Biological Process (BP) regulation of mitotic cell cycle 0.02326 Informative Inherited
Biological Process (BP) regulation of cell cycle process 0.6661 Informative Inherited
Biological Process (BP) regulation of cellular component movement 0.001782 Informative Inherited
Biological Process (BP) regulation of locomotion 0.001789 Informative Inherited
Biological Process (BP) apoptotic process 0.0896 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.8178 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of immune system process 0.9009 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.3484 Informative Inherited
Biological Process (BP) defense response 0.03928 Informative Inherited
Biological Process (BP) immune response 0.5617 Informative Inherited
Biological Process (BP) immune effector process 0.7356 Informative Inherited
Biological Process (BP) secondary metabolic process 0.09294 Informative Inherited
Biological Process (BP) regulation of nucleoside metabolic process 0.001742 Informative Inherited
Biological Process (BP) regulation of purine nucleotide metabolic process 0.002384 Informative Inherited
Biological Process (BP) response to hormone stimulus 0.7216 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.5611 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.6508 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 1 Informative Inherited
Biological Process (BP) regulation of cytokine production 1 Informative Inherited
Biological Process (BP) response to lipid 0.3954 Informative Inherited
Biological Process (BP) response to organic cyclic compound 1 Informative Inherited
Biological Process (BP) regulation of kinase activity 0.6287 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.0597 Informative Inherited
Biological Process (BP) positive regulation of protein modification process 0.1277 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.2128 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 0.1525 Informative Inherited
Biological Process (BP) gland development 0.001764 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.5508 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.2146 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.1604 Informative Inherited
Biological Process (BP) lipid localization 0.3913 Informative Inherited
Biological Process (BP) regulation of cell development 0.8495 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of peptidase activity 0.002239 Informative Inherited
Biological Process (BP) negative regulation of catalytic activity 0.1711 Informative Inherited
Biological Process (BP) response to nutrient levels 0.001212 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) cytoplasmic transport 1 Informative Inherited
Biological Process (BP) protein localization to organelle 1 Informative Inherited
Biological Process (BP) pigment metabolic process 0.001706 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.01361 Informative Inherited
Biological Process (BP) blood circulation 1 Informative Inherited
Biological Process (BP) epithelium development 0.3196 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.011 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.2018 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.6212 Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 6.598e-06 Highly Informative Direct
Biological Process (BP) protein phosphorylation 0 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) peptidyl-tyrosine modification 0 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) regulation of Rho GTPase activity 1.834e-10 Highly Informative Direct
Biological Process (BP) regulation of protein localization to nucleus 1.831e-08 Highly Informative Direct
Biological Process (BP) cellular response to growth factor stimulus 1.862e-08 Highly Informative Direct
Biological Process (BP) negative regulation of cell differentiation 2.111e-08 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 6.706e-08 Highly Informative Direct
Biological Process (BP) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1.027e-07 Highly Informative Direct
Biological Process (BP) regulation of cell adhesion 1.482e-07 Highly Informative Direct
Biological Process (BP) negative regulation of sequence-specific DNA binding transcription factor activity 2.141e-07 Highly Informative Direct
Biological Process (BP) positive regulation of intracellular transport 2.78e-07 Highly Informative Direct
Biological Process (BP) negative regulation of secretion 4.069e-07 Highly Informative Direct
Biological Process (BP) regulation of cell size 1.056e-06 Highly Informative Direct
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 1.095e-06 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 1.969e-06 Highly Informative Direct
Biological Process (BP) regulation of nucleocytoplasmic transport 4.333e-06 Highly Informative Direct
Biological Process (BP) regulation of intracellular protein transport 5.174e-06 Highly Informative Direct
Biological Process (BP) regulation of cellular response to growth factor stimulus 5.808e-06 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 1.116e-05 Highly Informative Direct
Biological Process (BP) phagocytosis 1.316e-05 Highly Informative Direct
Biological Process (BP) regulation of cysteine-type endopeptidase activity involved in apoptotic process 1.382e-05 Highly Informative Direct
Biological Process (BP) hormone transport 1.992e-05 Highly Informative Direct
Biological Process (BP) phenol-containing compound metabolic process 2.08e-05 Highly Informative Direct
Biological Process (BP) negative regulation of intracellular transport 3.434e-05 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 3.938e-05 Highly Informative Direct
Biological Process (BP) respiratory system development 5.779e-05 Highly Informative Direct
Biological Process (BP) telencephalon development 8.033e-05 Highly Informative Direct
Biological Process (BP) regulation of protein kinase B signaling cascade 9.471e-05 Highly Informative Direct
Biological Process (BP) organic hydroxy compound transport 0.0001166 Highly Informative Direct
Biological Process (BP) neuron projection development 0.0001215 Highly Informative Direct
Biological Process (BP) angiogenesis 0.0001591 Highly Informative Direct
Biological Process (BP) establishment or maintenance of cell polarity 0.0001887 Highly Informative Direct
Biological Process (BP) regulation of mononuclear cell proliferation 0.0002164 Highly Informative Direct
Biological Process (BP) sterol metabolic process 0.0002924 Highly Informative Direct
Biological Process (BP) symbiosis, encompassing mutualism through parasitism 0.0003181 Highly Informative Direct
Biological Process (BP) pattern specification process 0.0003468 Highly Informative Direct
Biological Process (BP) regulation of striated muscle tissue development 0.000368 Highly Informative Direct
Biological Process (BP) cell fate commitment 0.0005715 Highly Informative Direct
Biological Process (BP) multi-organism cellular process 0.0006004 Highly Informative Direct
Biological Process (BP) positive regulation of peptidyl-tyrosine phosphorylation 0.0006524 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.0007375 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.0007644 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0009775 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.00813 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 0.2061 Highly Informative Inherited
Biological Process (BP) stem cell development 0.3046 Highly Informative Inherited
Biological Process (BP) negative regulation of locomotion 0.008974 Highly Informative Inherited
Biological Process (BP) negative regulation of cellular component movement 0.01484 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 0.1449 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.3418 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.007296 Highly Informative Inherited
Biological Process (BP) positive regulation of protein kinase activity 0.01182 Highly Informative Inherited
Biological Process (BP) developmental growth 0.005956 Highly Informative Inherited
Biological Process (BP) mammary gland epithelium development 0.001814 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.05217 Highly Informative Inherited
Biological Process (BP) regulation of actin cytoskeleton organization 0.001163 Highly Informative Inherited
Biological Process (BP) protein tetramerization 0.001326 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.6763 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 0.1524 Highly Informative Inherited
Biological Process (BP) regulation of endocytosis 0.03258 Highly Informative Inherited
Biological Process (BP) post-embryonic development 1 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.3562 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.1486 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.7582 Highly Informative Inherited
Biological Process (BP) leukocyte migration 0.002495 Highly Informative Inherited
Biological Process (BP) regulation of synaptic transmission 0.003429 Highly Informative Inherited
Biological Process (BP) positive regulation of neurogenesis 0.7433 Highly Informative Inherited
Biological Process (BP) signal release 0.7061 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.4012 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 1 Highly Informative Inherited
Biological Process (BP) regulation of mitosis 0.04282 Highly Informative Inherited
Biological Process (BP) positive regulation of cell cycle process 0.07873 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.0972 Highly Informative Inherited
Biological Process (BP) negative regulation of endopeptidase activity 0.007406 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 1 Highly Informative Inherited
Biological Process (BP) wound healing 0.02486 Highly Informative Inherited
Biological Process (BP) regulation of protein catabolic process 0.4654 Highly Informative Inherited
Biological Process (BP) lipoprotein metabolic process 0.001209 Highly Informative Inherited
Biological Process (BP) regulation of T cell activation 1 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte proliferation 0.9154 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.3313 Highly Informative Inherited
Biological Process (BP) innate immune response 0.1142 Highly Informative Inherited
Biological Process (BP) negative regulation of protein transport 0.001849 Highly Informative Inherited
Biological Process (BP) response to peptide hormone stimulus 0.0106 Highly Informative Inherited
Biological Process (BP) cellular response to peptide 0.03073 Highly Informative Inherited
Biological Process (BP) positive regulation of Ras GTPase activity 1 Highly Informative Inherited
Biological Process (BP) positive regulation of cell activation 0.001516 Highly Informative Inherited
Biological Process (BP) response to alcohol 0.3124 Highly Informative Inherited
Biological Process (BP) negative regulation of cell growth 0.01349 Highly Informative Inherited
Biological Process (BP) membrane fusion 0.022 Highly Informative Inherited
Biological Process (BP) protein processing 0.001547 Highly Informative Inherited
Biological Process (BP) ear development 0.02154 Highly Informative Inherited
Biological Process (BP) epidermal cell differentiation 0.4551 Highly Informative Inherited
Biological Process (BP) post-embryonic organ development 0.9481 Highly Informative Inherited
Biological Process (BP) nuclear import 0.0131 Highly Informative Inherited
Biological Process (BP) protein import 0.02058 Highly Informative Inherited
Biological Process (BP) protein localization to nucleus 0.03413 Highly Informative Inherited
Biological Process (BP) protein targeting to nucleus 0.3427 Highly Informative Inherited
Biological Process (BP) regulation of blood pressure 0.001208 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) transferase activity 2.299e-13 Least Informative Direct
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 2.355e-05 Moderately Informative Direct
Molecular Function (MF) anion binding 0.1444 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) cation binding 1 Moderately Informative Inherited
Molecular Function (MF) structural molecule activity 0.01004 Moderately Informative Inherited
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) receptor binding 0 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) sulfur compound binding 6.97e-12 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 7.628e-11 Informative Direct
Molecular Function (MF) peptidase regulator activity 4.564e-07 Informative Direct
Molecular Function (MF) enzyme inhibitor activity 1.727e-05 Informative Direct
Molecular Function (MF) enzyme activator activity 6.886e-05 Informative Direct
Molecular Function (MF) inorganic cation transmembrane transporter activity 0.192 Informative Inherited
Molecular Function (MF) carboxylic acid binding 0.002646 Informative Inherited
Molecular Function (MF) amide binding 0.01986 Informative Inherited
Molecular Function (MF) metal ion transmembrane transporter activity 0.03011 Informative Inherited
Molecular Function (MF) peptidase activity 0.04594 Informative Inherited
Molecular Function (MF) lipid binding 0.4068 Informative Inherited
Molecular Function (MF) enzyme binding 0.9105 Informative Inherited
Molecular Function (MF) protein kinase activity 0 Highly Informative Direct
Molecular Function (MF) heparin binding 1.812e-11 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 2.887e-11 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 1.748e-09 Highly Informative Direct
Molecular Function (MF) calcium ion binding 1.263e-08 Highly Informative Direct
Molecular Function (MF) serine hydrolase activity 1.125e-07 Highly Informative Direct
Molecular Function (MF) hormone binding 1.378e-05 Highly Informative Direct
Molecular Function (MF) calcium ion transmembrane transporter activity 2.508e-05 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase inhibitor activity 3.281e-05 Highly Informative Direct
Molecular Function (MF) peptide binding 0.0001464 Highly Informative Direct
Molecular Function (MF) protein complex binding 0.00065 Highly Informative Direct
Molecular Function (MF) phosphatase regulator activity 0.01262 Highly Informative Inherited
Molecular Function (MF) amino acid binding 0.00232 Highly Informative Inherited
Molecular Function (MF) cation channel activity 0.006425 Highly Informative Inherited
Molecular Function (MF) ion gated channel activity 0.009103 Highly Informative Inherited
Molecular Function (MF) growth factor receptor binding 0.4049 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) cell projection 1.465e-08 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.05652 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 0.02081 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) endosome 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular membrane-bounded organelle 3.172e-12 Informative Direct
Cellular Component (CC) Golgi apparatus 6.612e-07 Informative Direct
Cellular Component (CC) lytic vacuole 0.0001094 Informative Direct
Cellular Component (CC) cell leading edge 0.0003885 Informative Direct
Cellular Component (CC) neuron projection 0.9752 Informative Inherited
Cellular Component (CC) cell junction 0.001076 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.09002 Informative Inherited
Cellular Component (CC) integral to membrane 0.9431 Informative Inherited
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) endosomal part 7.431e-08 Highly Informative Direct
Cellular Component (CC) receptor complex 7.92e-08 Highly Informative Direct
Cellular Component (CC) lysosome 1.256e-05 Highly Informative Direct
Cellular Component (CC) apical plasma membrane 1.381e-05 Highly Informative Direct
Cellular Component (CC) dendrite 0.0001536 Highly Informative Direct
Cellular Component (CC) cell body 0.000435 Highly Informative Direct
Cellular Component (CC) adherens junction 0.0009854 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 0.0009905 Highly Informative Direct
Cellular Component (CC) membrane raft 0.002671 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

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EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)8.291e-07Least InformativeDirect
Enzyme Commission (EC)Serine endopeptidases6.22e-06Moderately InformativeDirect
Enzyme Commission (EC)Receptor protein-tyrosine kinase0InformativeDirect
Enzyme Commission (EC)Furin0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.09955Least InformativeInherited
Disease Ontology (DO)immune system disease0.5096Least InformativeInherited
Disease Ontology (DO)hypersensitivity reaction type II disease0.006278Moderately InformativeInherited
Disease Ontology (DO)cell type cancer0.01151Moderately InformativeInherited
Disease Ontology (DO)benign neoplasm0.09261Moderately InformativeInherited
Disease Ontology (DO)nervous system cancer0.1163Moderately InformativeInherited
Disease Ontology (DO)urinary system cancer3.034e-05InformativeDirect
Disease Ontology (DO)malignant glioma0.0004317InformativeDirect
Disease Ontology (DO)gastrointestinal system cancer0.006999InformativeInherited
Disease Ontology (DO)organ system benign neoplasm0.07241InformativeInherited
Disease Ontology (DO)peripheral nervous system neoplasm0.4476InformativeInherited
Disease Ontology (DO)skin hemangioma9.956e-06Highly InformativeDirect
Disease Ontology (DO)primary thrombocytopenia1.248e-05Highly InformativeDirect
Disease Ontology (DO)neurofibroma2.387e-05Highly InformativeDirect
Disease Ontology (DO)colorectal cancer0.000214Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

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HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.1613Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digit0.002196Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vasculature0.01306Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the hand0.01512Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal respiratory system morphology0.3295Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the systemic arterial tree0.2916InformativeInherited
Phenotypic Abnormality (PA)Arachnodactyly0.0003203Highly InformativeDirect
Phenotypic Abnormality (PA)Dilatation of the ascending aorta0.0005386Highly InformativeDirect
Phenotypic Abnormality (PA)Emphysema0.000845Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

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MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype2.362e-06Least InformativeDirect
Mammalian Phenotype (MP)nervous system phenotype0.1106Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.13Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.3324Least InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology7.748e-07Moderately InformativeDirect
Mammalian Phenotype (MP)renal/urinary system phenotype3.952e-06Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system development0.0001391Moderately InformativeDirect
Mammalian Phenotype (MP)muscle phenotype0.0002586Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.002261Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic nervous system morphology0.007037Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.01651Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal gland morphology0.03856Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.06575Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.07485Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.08539Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular development0.1806Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.4776Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.56Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.8078Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal craniofacial morphology1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal lung morphology1.034e-06InformativeDirect
Mammalian Phenotype (MP)abnormal cranium morphology1.746e-05InformativeDirect
Mammalian Phenotype (MP)abnormal membranous labyrinth morphology0.0008625InformativeDirect
Mammalian Phenotype (MP)abnormal systemic artery morphology0.02058InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.0248InformativeInherited
Mammalian Phenotype (MP)abnormal neuron number0.1178InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle morphology0.1944InformativeInherited
Mammalian Phenotype (MP)abnormal angiogenesis0.2397InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear sensory epithelium morphology0.3288InformativeInherited
Mammalian Phenotype (MP)abnormal brain development0.3936InformativeInherited
Mammalian Phenotype (MP)abnormal hair cell morphology0.4885InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.5227InformativeInherited
Mammalian Phenotype (MP)decreased cell proliferation0.5866InformativeInherited
Mammalian Phenotype (MP)abnormal intestine morphology0.7491InformativeInherited
Mammalian Phenotype (MP)abnormal aorta tunica media morphology3.145e-05Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cardinal vein morphology9.993e-05Highly InformativeDirect
Mammalian Phenotype (MP)decreased organ of Corti supporting cell number0.0002132Highly InformativeDirect
Mammalian Phenotype (MP)aneurysm0.0003966Highly InformativeDirect
Mammalian Phenotype (MP)small kidney0.0006207Highly InformativeDirect
Mammalian Phenotype (MP)absent sebaceous gland0.0006253Highly InformativeDirect
Mammalian Phenotype (MP)abnormal olfactory bulb development0.01921Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear hair cell number0.05182Highly InformativeInherited
Mammalian Phenotype (MP)increased sensory neuron number0.07457Highly InformativeInherited
Mammalian Phenotype (MP)abnormal respiratory system development0.08288Highly InformativeInherited
Mammalian Phenotype (MP)abnormal ureteric bud morphology0.08577Highly InformativeInherited
Mammalian Phenotype (MP)abnormal diaphragm morphology0.4874Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear inner hair cell morphology0.7314Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval development variant0.4669Least InformativeInherited
Worm Phenotype (WP)organ system development variant3.679e-06Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant1.627e-05Moderately InformativeDirect
Worm Phenotype (WP)locomotion variant0.0006497Moderately InformativeDirect
Worm Phenotype (WP)larval lethal0.2271Moderately InformativeInherited
Worm Phenotype (WP)male morphology variant3.331e-05InformativeDirect
Worm Phenotype (WP)muscle cell morphology variant4.042e-05InformativeDirect
Worm Phenotype (WP)egg laying variant0.0001402InformativeDirect
Worm Phenotype (WP)body length variant0.0002221InformativeDirect
Worm Phenotype (WP)body width variant0.0003162InformativeDirect
Worm Phenotype (WP)activity level variant0.01925InformativeInherited
Worm Phenotype (WP)neuron development variant0.02399InformativeInherited
Worm Phenotype (WP)molt variant1.729e-07Highly InformativeDirect
Worm Phenotype (WP)myopodia present3.625e-07Highly InformativeDirect
Worm Phenotype (WP)loss of asymmetry ASE4.27e-06Highly InformativeDirect
Worm Phenotype (WP)paralyzed1.734e-05Highly InformativeDirect
Worm Phenotype (WP)muscle arm development defective2.228e-05Highly InformativeDirect
Worm Phenotype (WP)axon guidance variant5.658e-05Highly InformativeDirect
Worm Phenotype (WP)dauer arrest variant0.0005952Highly InformativeDirect
Worm Phenotype (WP)muscle system development variant0.005357Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

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FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)size defective7.928e-05InformativeDirect
Fly Phenotype (FP)cell polarity defective0.0001676InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0.09062Least InformativeInherited
Fly Anatomy (FA)multi-tissue structure0.1877Least InformativeInherited
Fly Anatomy (FA)larva0.1924Least InformativeInherited
Fly Anatomy (FA)organ system0.2079Least InformativeInherited
Fly Anatomy (FA)adult0.2921Least InformativeInherited
Fly Anatomy (FA)anatomical group0.3724Least InformativeInherited
Fly Anatomy (FA)cell0.9872Least InformativeInherited
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)multi-cell-component structure0.01383Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.06376Moderately InformativeInherited
Fly Anatomy (FA)neuron0.1029Moderately InformativeInherited
Fly Anatomy (FA)sensillum0.1036Moderately InformativeInherited
Fly Anatomy (FA)adult nervous system0.1311Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.1522Moderately InformativeInherited
Fly Anatomy (FA)external sensory organ0.1766Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.1947Moderately InformativeInherited
Fly Anatomy (FA)adult sense organ0.3401Moderately InformativeInherited
Fly Anatomy (FA)reproductive system0.3524Moderately InformativeInherited
Fly Anatomy (FA)developing material anatomical entity0.5011Moderately InformativeInherited
Fly Anatomy (FA)adult head0.5346Moderately InformativeInherited
Fly Anatomy (FA)integumentary specialisation0.0004185InformativeDirect
Fly Anatomy (FA)commissure0.0007979InformativeDirect
Fly Anatomy (FA)germline stem cell0.0009097InformativeDirect
Fly Anatomy (FA)tracheal system0.002099InformativeInherited
Fly Anatomy (FA)rhabdomeric photoreceptor cell0.005894InformativeInherited
Fly Anatomy (FA)alimentary canal0.007395InformativeInherited
Fly Anatomy (FA)synaptic neuropil0.009632InformativeInherited
Fly Anatomy (FA)primordium0.01023InformativeInherited
Fly Anatomy (FA)histaminergic neuron0.04461InformativeInherited
Fly Anatomy (FA)interneuron0.04917InformativeInherited
Fly Anatomy (FA)ommatidium0.04936InformativeInherited
Fly Anatomy (FA)circulatory system0.05014InformativeInherited
Fly Anatomy (FA)optic lobe neuron0.05327InformativeInherited
Fly Anatomy (FA)male reproductive system0.06331InformativeInherited
Fly Anatomy (FA)extended germ band embryo0.08342InformativeInherited
Fly Anatomy (FA)sensory organ cell0.09426InformativeInherited
Fly Anatomy (FA)dorsal closure embryo0.1054InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval digestive system0.1061InformativeInherited
Fly Anatomy (FA)labral segment0.1176InformativeInherited
Fly Anatomy (FA)pupa0.1576InformativeInherited
Fly Anatomy (FA)embryonic/larval central nervous system0.1673InformativeInherited
Fly Anatomy (FA)neuromere0.1872InformativeInherited
Fly Anatomy (FA)somatic stem cell0.6368InformativeInherited
Fly Anatomy (FA)ventral nervous system9.913e-06Highly InformativeDirect
Fly Anatomy (FA)hub cell5.678e-05Highly InformativeDirect
Fly Anatomy (FA)adult heart0.0001526Highly InformativeDirect
Fly Anatomy (FA)adult gut0.0007113Highly InformativeDirect
Fly Anatomy (FA)neuroblast of ventral nerve cord primordium0.002163Highly InformativeInherited
Fly Anatomy (FA)hindgut0.008141Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval neuron0.008556Highly InformativeInherited
Fly Anatomy (FA)larval procephalic segment0.01253Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval brain0.02428Highly InformativeInherited
Fly Anatomy (FA)inner photoreceptor cell0.02869Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

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ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)portion of tissue0.08824Least InformativeInherited
Zebrafish Anatomy (ZA)multi-tissue structure0.1642Least InformativeInherited
Zebrafish Anatomy (ZA)trunk0.3737Least InformativeInherited
Zebrafish Anatomy (ZA)head0.7447Least InformativeInherited
Zebrafish Anatomy (ZA)skeletal element0.2867Moderately InformativeInherited
Zebrafish Anatomy (ZA)suspensorium0.3059Moderately InformativeInherited
Zebrafish Anatomy (ZA)pharyngeal arch0.7816Moderately InformativeInherited
Zebrafish Anatomy (ZA)symplectic0.000341InformativeDirect
Zebrafish Anatomy (ZA)somite 20.0004237InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)central nervous system0.2152Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.4288Least InformativeInherited
Xenopus ANatomical entity (XAN)portion of tissue0.4572Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.7774Least InformativeInherited
Xenopus ANatomical entity (XAN)cell1Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.01255Moderately InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.07468Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.3447Moderately InformativeInherited
Xenopus ANatomical entity (XAN)surface structure0.9596Moderately InformativeInherited
Xenopus ANatomical entity (XAN)visual system1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)mesenchyme6.302e-06InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm1.789e-05InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0.0001201InformativeDirect
Xenopus ANatomical entity (XAN)vestibuloauditory system0.0002574InformativeDirect
Xenopus ANatomical entity (XAN)endoderm0.0003153InformativeDirect
Xenopus ANatomical entity (XAN)pre-chordal neural plate0.0003653InformativeDirect
Xenopus ANatomical entity (XAN)anatomical space0.0007626InformativeDirect
Xenopus ANatomical entity (XAN)spinal cord0.003477InformativeInherited
Xenopus ANatomical entity (XAN)tail0.592InformativeInherited
Xenopus ANatomical entity (XAN)hypochord1.643e-05Highly InformativeDirect
Xenopus ANatomical entity (XAN)chordoneural hinge0.0004293Highly InformativeDirect
Xenopus ANatomical entity (XAN)optic vesicle0.0005831Highly InformativeDirect
Xenopus ANatomical entity (XAN)midbrain0.0007184Highly InformativeDirect
Xenopus ANatomical entity (XAN)floor plate0.00079Highly InformativeDirect
Xenopus ANatomical entity (XAN)zygote0.001469Highly InformativeInherited
Xenopus ANatomical entity (XAN)neural plate border0.00226Highly InformativeInherited
Xenopus DEvelopment stage (XDE)embryonic stage6.366e-05Least InformativeDirect
Xenopus DEvelopment stage (XDE)NF stage0.0001543Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

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EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)3.125e-06Moderately InformativeDirect
Enzyme Commission (EC)Protein-tyrosine kinases0InformativeDirect
Enzyme Commission (EC)Serine endopeptidases5.718e-07InformativeDirect
Enzyme Commission (EC)Receptor protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

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KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processDifferentiation0Moderately InformativeDirect
Biological processApoptosis8.252e-07Moderately InformativeDirect
Biological processLipid metabolism0.4959Moderately InformativeInherited
Biological processAngiogenesis0InformativeDirect
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processHemostasis0InformativeDirect
Biological processNeurogenesis0InformativeDirect
Biological processWnt signaling pathway0InformativeDirect
Biological processSensory transduction4.764e-14InformativeDirect
Biological processSteroid metabolism1.35e-13InformativeDirect
Biological processLipid transport7.04e-11InformativeDirect
Biological processInnate immunity1.332e-06InformativeDirect
Biological processCytolysis1.078e-05InformativeDirect
Biological processBlood coagulation0Highly InformativeDirect
Biological processCholesterol metabolism0Highly InformativeDirect
Biological processGrowth regulation0Highly InformativeDirect
Biological processNotch signaling pathway0Highly InformativeDirect
Biological processComplement alternate pathway2.61e-07Highly InformativeDirect
Biological processDNA synthesis3.587e-06Highly InformativeDirect
Biological processComplement pathway9.518e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentEndosome8.649e-14Moderately InformativeDirect
Cellular componentGolgi apparatus9.277e-05Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Cellular componentLysosome3.735e-06InformativeDirect
Cellular componentCoated pit0Highly InformativeDirect
Coding sequence diversityPolymorphism1.185e-05Moderately InformativeDirect
DiseaseDisease mutation1.513e-06Least InformativeDirect
DiseaseDwarfism0.000898Highly InformativeDirect
DomainRepeat0Least InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane1.276e-08Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainANK repeat7.956e-05InformativeDirect
DomainLaminin EGF-like domain6.707e-08Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionHeparin-binding0InformativeDirect
Molecular functionGrowth factor binding