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OMPA-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Transmembrane beta-barrels [ 56924] (6)
Superfamily:   OMPA-like [ 56925] (4)
Families:   Outer membrane protein [ 56926] (3)
  Outer membrane enzyme PagP [ 82874]
  GNA1870 immunodominant domain-like [ 144097]
  PsbO-like [ 161115]

 Superfamily statistics
Genomes (1,123) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 6,707 33,638 9
Proteins 6,598 33,050 9

 Functional annotation
General category Processes_IC
Detailed category Transport

Document: Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.0063420.5445Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.058210.8254Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process1.409e-070.0001712Moderately InformativeDirect
Biological Process (BP)lipid biosynthetic process1.932e-091.838e-05Moderately InformativeDirect
Biological Process (BP)organophosphate metabolic process5.344e-070.0007276Moderately InformativeDirect
Biological Process (BP)cellular lipid metabolic process2.161e-070.0009295Moderately InformativeDirect
Biological Process (BP)carbohydrate derivative metabolic process9.235e-070.001152Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process7.3e-050.1321Moderately InformativeInherited
Biological Process (BP)membrane lipid metabolic process09.399e-12InformativeDirect
Biological Process (BP)phospholipid metabolic process7.721e-141.867e-08InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process8.802e-131.443e-08InformativeDirect
Biological Process (BP)oligosaccharide metabolic process07.834e-10Highly InformativeDirect
Biological Process (BP)membrane lipid biosynthetic process03.682e-14Highly InformativeDirect
Molecular Function (MF)transferase activity0.00044480.3309Least InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups9.21e-139.239e-09InformativeDirect
Molecular Function (MF)O-acyltransferase activity4.689e-093.707e-08Highly InformativeDirect
Cellular Component (CC)membrane2.356e-050Least InformativeDirect
Cellular Component (CC)external encapsulating structure00InformativeDirect
Cellular Component (CC)cell envelope00Highly InformativeDirect
Cellular Component (CC)external encapsulating structure part00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.5445 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.8254 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.0001712 Moderately Informative Direct
Biological Process (BP) lipid biosynthetic process 1.838e-05 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.0007276 Moderately Informative Direct
Biological Process (BP) cellular lipid metabolic process 0.0009295 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.001152 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.1321 Moderately Informative Inherited
Biological Process (BP) membrane lipid metabolic process 9.399e-12 Informative Direct
Biological Process (BP) phospholipid metabolic process 1.867e-08 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 1.443e-08 Informative Direct
Biological Process (BP) oligosaccharide metabolic process 7.834e-10 Highly Informative Direct
Biological Process (BP) membrane lipid biosynthetic process 3.682e-14 Highly Informative Direct
Molecular Function (MF) transferase activity 0.3309 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 9.239e-09 Informative Direct
Molecular Function (MF) O-acyltransferase activity 3.707e-08 Highly Informative Direct
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) external encapsulating structure 0 Informative Direct
Cellular Component (CC) cell envelope 0 Highly Informative Direct
Cellular Component (CC) external encapsulating structure part 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.001501Least InformativeInherited
Biological processIon transport4.622e-16Moderately InformativeDirect
Biological processPhotosynthesis7.859e-14InformativeDirect
Biological processVirulence2.036e-10InformativeDirect
Biological processPhotosystem II0Highly InformativeDirect
Biological processConjugation0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentPlastid0.003452Moderately InformativeInherited
Cellular componentCell outer membrane0InformativeDirect
Cellular componentThylakoid1.822e-07InformativeDirect
Cellular componentTransmembrane beta strand0Highly InformativeDirect
Cellular componentChloroplast4.547e-05Highly InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane0.01875Least InformativeInherited
Molecular functionManganese2.191e-09Moderately InformativeDirect
Post-translational modificationTransferase0.001225Least InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationPalmitate0.0008735Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a OMPA-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the OMPA-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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© Copyright 2013 The SUPERFAMILY authors and Julian Gough.