SUPERFAMILY 1.75 HMM library and genome assignments server

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Non-globular alpha+beta subunits of globular proteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Non-globular alpha+beta subunits of globular proteins [ 56567]
Superfamily:   Non-globular alpha+beta subunits of globular proteins [ 56568] (3)
Families:   Phycoerythrin 545 alpha-subunits [ 56569]
  Virulence effector SptP domain [ 69868]
  Ubiquinol-cytochrome c reductase 8 kDa protein [ 90077]


Superfamily statistics
Genomes (114) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 152 913 6
Proteins 149 907 6


Functional annotation
General category Metabolism
Detailed category Photosynthesis

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.000000000004856Least InformativeDirect
Enzyme Commission (EC)With a cytochrome as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.000000000005509Least InformativeDirect
Enzyme Commission (EC)Hydrolases0.6625Least InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0.0003529Moderately InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0.0000002736InformativeDirect
Enzyme Commission (EC)Acting on diphenols and related substances as donors0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.000000000005366Least InformativeDirect
Biological processElectron transport0InformativeDirect
Biological processVirulence0.000000000000002773InformativeDirect
Biological processPhotosynthesis0.00002978InformativeDirect
Biological processRespiratory chain0.0003599Highly InformativeDirect
Cellular componentMembrane0.0000003043Least InformativeDirect
Cellular componentMitochondrion0.00000000000005751Moderately InformativeDirect
Cellular componentSecreted0.00005004Moderately InformativeDirect
Cellular componentPlastid0.0027Moderately InformativeInherited
Cellular componentMitochondrion inner membrane0InformativeDirect
Cellular componentThylakoid0.00005943InformativeDirect
Cellular componentChloroplast0.0002175InformativeDirect
DomainTransmembrane0.001153Least InformativeInherited
DomainTransit peptide0Moderately InformativeDirect
Molecular functionMetal-binding0.0001625Least InformativeDirect
Molecular functionIron0.0000000000001161Moderately InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular function2Fe-2S0InformativeDirect
Molecular functionChromophore0.000000003578InformativeDirect
Post-translational modificationOxidoreductase0.0000000003621Moderately InformativeDirect
Post-translational modificationDisulfide bond0.000003918Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR011070 SSF56568 Protein matches
Abstract

Certain globular proteins from different functional families contain non-globular alpha+beta subunits. These proteins do not form a true superfamily, but share a similar topology in their non-globular subunits. Proteins that display this structure include phycoerythrin 545 alpha subunits , which are light-harvesting biliproteins found in cryptomonads [PubMed9425063], the chaperone-binding domain of the virulence effector SptP from Salmonella typhimurium, which acts to modulate host cellular responses [PubMed11689946], and the ubiquinol-cytochrome c reductase 8-kDa protein , an integral membrane protein complex essential to cellular respiration [PubMed12269811].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Non-globular alpha+beta subunits of globular proteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Non-globular alpha+beta subunits of globular proteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]