SUPERFAMILY 1.75 HMM library and genome assignments server


C-type lectin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Families:   C-type lectin domain [ 56437] (28)
  Aerolysin/Pertussis toxin (APT) domain [ 56467] (2)
  Invasin/intimin cell-adhesion fragment, C-terminal domain [ 56472] (2)
  Link domain [ 56477] (2)
  Endostatin [ 56480] (2)
  Noncollagenous (NC1) domain of collagen IV [ 75585]
  Sulfatase-modifying factor-like [ 143959] (2)
  Mtd variable domain [ 143964]


Superfamily statistics
Genomes (1,619) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 26,537 39,333 125
Proteins 19,012 31,472 121


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of cellular process0.59921Least InformativeInherited
Biological Process (BP)single-organism cellular process0.15560.1278Least InformativeInherited
Biological Process (BP)response to stimulus0.0011851.634e-09Least InformativeInherited
Biological Process (BP)multicellular organismal process0.16111.211e-13Least InformativeInherited
Biological Process (BP)immune system process1.169e-061.091e-14Moderately InformativeDirect
Biological Process (BP)multi-organism process7.615e-091.886e-06Moderately InformativeDirect
Biological Process (BP)positive regulation of response to stimulus0.040991.628e-11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.10741Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.050130.232Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.062941Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.19450.7593Moderately InformativeInherited
Biological Process (BP)signal transduction0.040010.03421Moderately InformativeInherited
Biological Process (BP)defense response5.6e-060InformativeDirect
Biological Process (BP)immune response0.00015610.0001175InformativeDirect
Biological Process (BP)biological adhesion3.817e-110InformativeDirect
Biological Process (BP)regulation of immune response0.00036883.831e-10InformativeDirect
Biological Process (BP)negative regulation of developmental process0.00047240.1004InformativeInherited
Biological Process (BP)positive regulation of cell proliferation0.00026870.7036InformativeInherited
Biological Process (BP)positive regulation of immune system process0.02579.819e-11InformativeInherited
Biological Process (BP)regulation of defense response0.34290.33InformativeInherited
Biological Process (BP)ossification0.0001781.379e-08Highly InformativeDirect
Biological Process (BP)cell adhesion2.5e-110Highly InformativeDirect
Biological Process (BP)regulation of wound healing5.937e-060.003884Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation2.658e-080.01528Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.00021440.3192Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.00018660.06388Highly InformativeInherited
Biological Process (BP)immune response-activating signal transduction0.64090.6653Highly InformativeInherited
Biological Process (BP)positive regulation of defense response0.0026626.158e-06Highly InformativeInherited
Biological Process (BP)regulation of innate immune response0.0090077.189e-06Highly InformativeInherited
Molecular Function (MF)binding3.87e-110Least InformativeDirect
Molecular Function (MF)receptor activity8.188e-090InformativeDirect
Molecular Function (MF)monosaccharide binding10.7761Highly InformativeInherited
Cellular Component (CC)membrane0.00069070Least InformativeDirect
Cellular Component (CC)plasma membrane1.555e-050Moderately InformativeDirect
Cellular Component (CC)extracellular region part5.632e-060Moderately InformativeDirect
Cellular Component (CC)cell surface8.158e-120InformativeDirect
Cellular Component (CC)extracellular matrix5.07e-060InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix9.677e-050Highly InformativeDirect
Cellular Component (CC)extracellular matrix part3.891e-050Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) multicellular organismal process 1.211e-13 Least Informative Direct
Biological Process (BP) developmental process 2.087e-08 Least Informative Direct
Biological Process (BP) response to stimulus 1.634e-09 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.1278 Least Informative Inherited
Biological Process (BP) localization 0.6982 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) immune system process 1.091e-14 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 1.628e-11 Moderately Informative Direct
Biological Process (BP) multi-organism process 1.886e-06 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.7593 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.001523 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.05975 Moderately Informative Inherited
Biological Process (BP) reproduction 0.4932 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.232 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.8199 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.4452 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.1423 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.03421 Moderately Informative Inherited
Biological Process (BP) regulation of cytokine production 1.468e-09 Informative Direct
Biological Process (BP) positive regulation of immune system process 9.819e-11 Informative Direct
Biological Process (BP) regulation of immune effector process 0.0004324 Informative Direct
Biological Process (BP) muscle system process 4.294e-06 Informative Direct
Biological Process (BP) cellular component movement 1.676e-05 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) immune response 0.0001175 Informative Direct
Biological Process (BP) response to wounding 0.0001419 Informative Direct
Biological Process (BP) vesicle-mediated transport 2.544e-05 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) locomotion 1.833e-05 Informative Direct
Biological Process (BP) regulation of immune response 3.831e-10 Informative Direct
Biological Process (BP) regulation of secretion 0.0009755 Informative Direct
Biological Process (BP) positive regulation of transport 2.487e-07 Informative Direct
Biological Process (BP) cell projection organization 0.005188 Informative Inherited
Biological Process (BP) response to oxidative stress 0.3076 Informative Inherited
Biological Process (BP) generation of neurons 0.1625 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.4714 Informative Inherited
Biological Process (BP) tube development 0.005202 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) reproductive system development 1 Informative Inherited
Biological Process (BP) response to other organism 0.01599 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 0.001137 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.1622 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.1927 Informative Inherited
Biological Process (BP) regulation of defense response 0.33 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.3663 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.3051 Informative Inherited
Biological Process (BP) regulation of ion transport 0.1424 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.1004 Informative Inherited
Biological Process (BP) leukocyte activation 0.2811 Informative Inherited
Biological Process (BP) gland development 0.2035 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) positive regulation of cell proliferation 0.7036 Informative Inherited
Biological Process (BP) muscle structure development 0.7106 Informative Inherited
Biological Process (BP) muscle tissue development 0.431 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.8681 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) ossification 1.379e-08 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte mediated immunity 0 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 6.549e-07 Highly Informative Direct
Biological Process (BP) chemotaxis 8.161e-05 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.0004845 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.0001753 Highly Informative Direct
Biological Process (BP) regulation of endocytosis 0.0007288 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) glycosaminoglycan metabolic process 0.0002196 Highly Informative Direct
Biological Process (BP) regulation of cell killing 0 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 6.158e-06 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.0003482 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.0001153 Highly Informative Direct
Biological Process (BP) multicellular organismal metabolic process 1.586e-08 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 7.189e-06 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in neuron differentiation 9.68e-05 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0003913 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0.000615 Highly Informative Direct
Biological Process (BP) chemical homeostasis within a tissue 3.781e-06 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 1.041e-07 Highly Informative Direct
Biological Process (BP) regulation of coagulation 0.0001146 Highly Informative Direct
Biological Process (BP) axon development 0.0001702 Highly Informative Direct
Biological Process (BP) regulation of protein processing 2.717e-12 Highly Informative Direct
Biological Process (BP) renal system development 6.187e-08 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.000547 Highly Informative Direct
Biological Process (BP) regulation of hemostasis 0.0005076 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.009416 Highly Informative Inherited
Biological Process (BP) cell projection morphogenesis 0.002846 Highly Informative Inherited
Biological Process (BP) regulation of wound healing 0.003884 Highly Informative Inherited
Biological Process (BP) defense response to bacterium 0.2865 Highly Informative Inherited
Biological Process (BP) regulation of cytokine secretion 0.0213 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.2893 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.01528 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.3192 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 0.02991 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.06388 Highly Informative Inherited
Biological Process (BP) aging 0.01573 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.09648 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.001183 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.5539 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte mediated immunity 0.002412 Highly Informative Inherited
Biological Process (BP) inflammatory response 0.004835 Highly Informative Inherited
Biological Process (BP) wound healing 0.00864 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.6653 Highly Informative Inherited
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0.002695 Highly Informative Inherited
Biological Process (BP) humoral immune response 0.06651 Highly Informative Inherited
Biological Process (BP) innate immune response 0.8217 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) structural molecule activity 1.756e-05 Moderately Informative Direct
Molecular Function (MF) anion binding 0.3386 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.03444 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) receptor binding 0.0001309 Informative Direct
Molecular Function (MF) protein dimerization activity 2.883e-06 Informative Direct
Molecular Function (MF) molecular transducer activity 3.833e-06 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0 Informative Direct
Molecular Function (MF) sulfur compound binding 7.529e-07 Informative Direct
Molecular Function (MF) enzyme binding 0.006919 Informative Inherited
Molecular Function (MF) calcium ion binding 1.936e-10 Highly Informative Direct
Molecular Function (MF) heparin binding 1.552e-07 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 1.645e-06 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.7761 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.06533 Moderately Informative Inherited
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) integral to membrane 0.02026 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.9059 Informative Inherited
Cellular Component (CC) nucleolus 0.2005 Informative Inherited
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 8.911e-06 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0 Highly Informative Direct
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) nucleolar part 2.577e-10 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details) Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)urinary system disease0.01509Moderately InformativeInherited
Disease Ontology (DO)lung disease0.01655Moderately InformativeInherited
Disease Ontology (DO)glomerulonephritis7.574e-05InformativeDirect
Disease Ontology (DO)opportunistic mycosis0.0004367InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.5122Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the globe0.09976Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.2979Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of urine homeostasis0.003041InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.004034InformativeInherited
Phenotypic Abnormality (PA)Abnormal renal physiology0.006401InformativeInherited
Phenotypic Abnormality (PA)Anterior lenticonus1.02e-08Highly InformativeDirect
Phenotypic Abnormality (PA)Hematuria0.0003459Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype2.387e-06Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.003794Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.2154Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.3894Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.9143Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal protein level1.812e-05Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell physiology0.003791Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.1015Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.1077Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2433Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.5248Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.7863Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.8235Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.8485Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.9825Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal liver physiology0.0009692InformativeDirect
Mammalian Phenotype (MP)abnormal leukocyte migration0.02842InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.05228InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.085InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.2491InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.3302InformativeInherited
Mammalian Phenotype (MP)skin hemorrhage0.0005102Highly InformativeDirect
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0005888Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating interleukin-17 level0.05932Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.1171Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.1214Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)epithelium0.01864Moderately InformativeInherited
Fly Anatomy (FA)epithelial tube0.0006067InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0.0006488Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0.0001238Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases3.69e-05Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase1.296e-08InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity1.219e-07InformativeDirect
Biological processCytolysis0.0001349InformativeDirect
Biological processAngiogenesis0.0004228InformativeDirect
Biological processAcute phase3.21e-11Highly InformativeDirect
Biological processAdaptive immunity1.275e-07Highly InformativeDirect
Biological processHemolysis1.738e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Coding sequence diversityPolymorphism2.908e-05Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane5.876e-07Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainSignal-anchor0InformativeDirect
DomainImmunoglobulin domain4.186e-08InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi0Highly InformativeDirect
DomainLaminin EGF-like domain1.53e-10Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationToxin0InformativeDirect
Post-translational modificationAntimicrobial3.398e-10InformativeDirect
Post-translational modificationHemagglutinin0Highly InformativeDirect
Post-translational modificationHemostasis impairing toxin0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPalmitate0.0006456Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.001237Least InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 72 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 72 hidden Markov models representing the C-type lectin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]