|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
calcium-dependent cell-cell adhesion |
0.0006594 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immune system process |
2.258e-14 |
1.398 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
7.485e-07 |
0.6383 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
3.704e-06 |
0.8182 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of natural killer cell mediated immunity |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular senescence |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein processing |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
natural killer cell activation |
6.291e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
extracellular structure organization |
3.085e-13 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of response to DNA damage stimulus |
1.29e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell killing |
6.147e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to DNA damage stimulus |
6.694e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell aging |
9.477e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
collagen catabolic process |
1.857e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
phagocytosis, recognition |
4.543e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal catabolic process |
5.803e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
reactive oxygen species metabolic process |
7.635e-09 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of anion transport |
1.076e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein secretion |
1.279e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
ureteric bud morphogenesis |
1.71e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
prostate gland development |
1.76e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
collagen metabolic process |
2.003e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal macromolecule metabolic process |
5.409e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
branching involved in ureteric bud morphogenesis |
6.063e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
glycosaminoglycan catabolic process |
7.661e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cytokine production |
1.061e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
renal system development |
1.522e-07 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
6.614e-07 |
0.8069 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
1.782e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
1.825e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
surfactant homeostasis |
2.182e-06 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to oxidative stress |
4.13e-06 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
nephron development |
5.126e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of response to stimulus |
6.557e-06 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
endocytosis |
9.084e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
axon guidance |
1.039e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of immune response |
1.45e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
response to organophosphorus |
1.55e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
synapse organization |
1.572e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
Wnt receptor signaling pathway |
3.545e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
ureteric bud development |
3.586e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis involved in neuron differentiation |
9.488e-05 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of angiogenesis |
0.0001333 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
extracellular matrix disassembly |
0.0002608 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell recognition |
0.0002907 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
neuron projection development |
0.0004048 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of establishment of protein localization |
0.0004438 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
skeletal muscle tissue development |
0.000665 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
gland morphogenesis |
0.0006678 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
taxis |
0.0007488 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte mediated cytotoxicity |
0.0008771 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cytokine secretion |
0.000941 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to stimulus |
0.8547 |
0.7645 |
-- |
INHERITED FROM: oxidative stress-induced premature senescence || cellular response to oxidative stress || innate immune response activating cell surface receptor signaling pathway || cellular senescence || stress-induced premature senescence || Wnt receptor signaling pathway |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: reactive oxygen species metabolic process |
| Biological Process (BP) |
regulation of primary metabolic process |
1 |
0.7852 |
-- |
INHERITED FROM: regulation of protein processing || positive regulation of plasminogen activation || regulation of cytokine biosynthetic process || regulation of plasminogen activation || positive regulation of protein processing |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
1 |
0.7959 |
-- |
INHERITED FROM: regulation of protein processing || positive regulation of plasminogen activation || regulation of cytokine biosynthetic process || regulation of plasminogen activation || positive regulation of protein processing |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.0455 |
1.658 |
-- |
INHERITED FROM: ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || branching involved in ureteric bud morphogenesis || morphogenesis of a branching epithelium || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
tube morphogenesis |
0.03001 |
1.854 |
-- |
INHERITED FROM: ureteric bud morphogenesis || branching involved in ureteric bud morphogenesis |
| Biological Process (BP) |
reproductive process |
1 |
1.143 |
-- |
INHERITED FROM: branching involved in prostate gland morphogenesis || prostate gland development || prostate gland epithelium morphogenesis || prostate gland morphogenesis |
| Biological Process (BP) |
reproductive structure development |
0.6665 |
1.658 |
-- |
INHERITED FROM: branching involved in prostate gland morphogenesis || prostate gland development || prostate gland morphogenesis || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
regulation of endocytosis |
0.001699 |
2.222 |
-- |
INHERITED FROM: regulation of phagocytosis |
| Biological Process (BP) |
regulation of cellular localization |
0.04989 |
1.357 |
-- |
INHERITED FROM: positive regulation of cytokine secretion || positive regulation of protein secretion |
| Biological Process (BP) |
regulation of cytokine secretion |
0.01046 |
2.222 |
-- |
INHERITED FROM: positive regulation of cytokine secretion |
| Biological Process (BP) |
regulation of protein transport |
0.1339 |
1.658 |
-- |
INHERITED FROM: positive regulation of protein secretion || positive regulation of cytokine secretion |
| Biological Process (BP) |
tissue homeostasis |
0.0859 |
1.854 |
-- |
INHERITED FROM: chemical homeostasis within a tissue || surfactant homeostasis |
| Biological Process (BP) |
chemical homeostasis |
0.742 |
1.208 |
-- |
INHERITED FROM: chemical homeostasis within a tissue || surfactant homeostasis |
| Biological Process (BP) |
striated muscle cell development |
0.01934 |
1.854 |
-- |
INHERITED FROM: muscle fiber development |
| Biological Process (BP) |
muscle cell development |
0.05266 |
1.796 |
-- |
INHERITED FROM: muscle fiber development |
| Biological Process (BP) |
striated muscle cell differentiation |
0.1358 |
1.745 |
-- |
INHERITED FROM: muscle fiber development |
| Biological Process (BP) |
muscle cell differentiation |
0.2615 |
1.658 |
-- |
INHERITED FROM: muscle fiber development |
| Biological Process (BP) |
cellular component organization |
1 |
0.6819 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || extracellular matrix organization || axonogenesis || extracellular matrix disassembly || neuron projection development || axon guidance || synapse organization || motor neuron axon guidance || glomerular basement membrane development || extracellular structure organization |
| Biological Process (BP) |
cell development |
0.9633 |
1.222 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || motor neuron axon guidance || axonogenesis || neuron projection development || muscle fiber development || axon guidance |
| Biological Process (BP) |
neurogenesis |
0.6409 |
1.357 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || motor neuron axon guidance || axonogenesis || neuron projection development || axon guidance |
| Biological Process (BP) |
cellular developmental process |
1 |
0.9666 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || neuron projection development || muscle fiber development || axon guidance || motor neuron axon guidance |
| Biological Process (BP) |
neuron development |
0.01513 |
1.796 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || neuron projection development || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
0.001802 |
1.745 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
cell morphogenesis |
0.0615 |
1.658 |
-- |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
regulation of biological process |
0.629 |
0.4486 |
-- |
INHERITED FROM: positive regulation of response to stimulus || regulation of response to stress || positive regulation of fatty acid transport || positive regulation of cytokine secretion || complement activation, lectin pathway || positive regulation of organic acid transport || regulation of icosanoid secretion || negative regulation of innate immune response || regulation of osteoclast differentiation || negative regulation of cell killing || positive regulation of ion transport || positive regulation of natural killer cell mediated cytotoxicity || regulation of leukocyte mediated immunity || positive regulation of icosanoid secretion || positive regulation of arachidonic acid secretion || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of interferon-gamma production || regulation of localization || positive regulation of immune response || positive regulation of protein secretion || negative regulation of angiogenesis || innate immune response activating cell surface receptor signaling pathway || positive regulation of lipid transport || positive regulation of secretion || positive regulation of response to DNA damage stimulus || positive regulation of plasminogen activation || regulation of cell killing || regulation of cytokine production || positive regulation of immune effector process || regulation of response to stimulus || regulation of arachidonic acid secretion || regulation of natural killer cell mediated immunity || positive regulation of immune system process || positive regulation of DNA damage response, signal transduction by p53 class mediator || negative regulation of myeloid leukocyte differentiation || regulation of immune system process || regulation of cytokine biosynthetic process || regulation of fatty acid transport || positive regulation of transport || positive regulation of biological process || positive regulation of natural killer cell mediated immunity || regulation of phagocytosis || regulation of protein processing || regulation of immune response || regulation of natural killer cell mediated cytotoxicity || regulation of plasminogen activation || negative regulation of osteoclast differentiation || positive regulation of signal transduction by p53 class mediator || Wnt receptor signaling pathway || regulation of response to DNA damage stimulus || regulation of lymphocyte mediated immunity || regulation of lipid transport || regulation of establishment of protein localization || regulation of organic acid transport || positive regulation of cell killing || regulation of leukocyte mediated cytotoxicity || regulation of anion transport || positive regulation of protein processing || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
biological regulation |
0.4027 |
0.4202 |
-- |
INHERITED FROM: positive regulation of response to stimulus || surfactant homeostasis || regulation of response to stress || positive regulation of fatty acid transport || positive regulation of cytokine secretion || complement activation, lectin pathway || positive regulation of organic acid transport || regulation of icosanoid secretion || negative regulation of innate immune response || regulation of osteoclast differentiation || negative regulation of cell killing || positive regulation of ion transport || positive regulation of natural killer cell mediated cytotoxicity || regulation of leukocyte mediated immunity || positive regulation of icosanoid secretion || positive regulation of arachidonic acid secretion || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of interferon-gamma production || regulation of localization || positive regulation of immune response || positive regulation of protein secretion || negative regulation of angiogenesis || innate immune response activating cell surface receptor signaling pathway || positive regulation of lipid transport || positive regulation of secretion || positive regulation of response to DNA damage stimulus || positive regulation of plasminogen activation || regulation of cell killing || regulation of cytokine production || positive regulation of immune effector process || regulation of response to stimulus || chemical homeostasis within a tissue || regulation of arachidonic acid secretion || regulation of natural killer cell mediated immunity || positive regulation of immune system process || positive regulation of DNA damage response, signal transduction by p53 class mediator || negative regulation of myeloid leukocyte differentiation || regulation of immune system process || regulation of cytokine biosynthetic process || regulation of fatty acid transport || positive regulation of transport || positive regulation of biological process || positive regulation of natural killer cell mediated immunity || regulation of phagocytosis || regulation of protein processing || regulation of immune response || regulation of natural killer cell mediated cytotoxicity || regulation of plasminogen activation || negative regulation of osteoclast differentiation || positive regulation of signal transduction by p53 class mediator || Wnt receptor signaling pathway || regulation of response to DNA damage stimulus || regulation of lymphocyte mediated immunity || regulation of lipid transport || regulation of establishment of protein localization || regulation of organic acid transport || positive regulation of cell killing || regulation of leukocyte mediated cytotoxicity || regulation of anion transport || positive regulation of protein processing || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
positive regulation of lymphocyte mediated immunity |
0.1754 |
2.222 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
positive regulation of defense response |
0.002893 |
2.398 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || innate immune response activating cell surface receptor signaling pathway || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
positive regulation of leukocyte mediated cytotoxicity |
0.8245 |
2.398 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
negative regulation of immune response |
0.0192 |
2.398 |
-- |
INHERITED FROM: negative regulation of innate immune response |
| Biological Process (BP) |
negative regulation of defense response |
0.1744 |
2.699 |
-- |
INHERITED FROM: negative regulation of innate immune response |
| Biological Process (BP) |
negative regulation of biological process |
1 |
0.8665 |
-- |
INHERITED FROM: negative regulation of osteoclast differentiation || negative regulation of innate immune response || negative regulation of angiogenesis || negative regulation of cell killing || negative regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
negative regulation of leukocyte differentiation |
0.001916 |
2.398 |
-- |
INHERITED FROM: negative regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
regulation of cell differentiation |
1 |
1.357 |
-- |
INHERITED FROM: regulation of osteoclast differentiation || negative regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: multicellular organismal macromolecule metabolic process || positive regulation of response to stimulus || response to purine-containing compound || surfactant homeostasis || natural killer cell activation || cytokine production || regulation of response to stress || cell activation || positive regulation of cytokine secretion || chemotaxis || complement activation, lectin pathway || biological adhesion || positive regulation of organic acid transport || regulation of icosanoid secretion || extracellular structure organization || immune system process || negative regulation of cell killing || multicellular organismal process || axonogenesis || cell-matrix adhesion || positive regulation of ion transport || motor neuron axon guidance || cell aging || regulation of DNA damage response, signal transduction by p53 class mediator || glomerular basement membrane development || aminoglycan catabolic process || positive regulation of interferon-gamma production || system development || bone mineralization || positive regulation of protein secretion || replicative senescence || innate immune response activating cell surface receptor signaling pathway || collagen catabolic process || nephron development || positive regulation of response to DNA damage stimulus || gland morphogenesis || prostate gland morphogenesis || endocytosis || response to ATP || regulation of cytokine production || developmental process || glycosaminoglycan catabolic process || positive regulation of immune effector process || regulation of natural killer cell mediated immunity || positive regulation of DNA damage response, signal transduction by p53 class mediator || cellular response to oxidative stress || negative regulation of myeloid leukocyte differentiation || regulation of immune system process || branching involved in prostate gland morphogenesis || biomineral tissue development || stress-induced premature senescence || multicellular organismal catabolic process || cellular defense response || response to organophosphorus || positive regulation of natural killer cell mediated immunity || regulation of phagocytosis || extracellular matrix disassembly || axon guidance || multi-organism process || prostate gland epithelium morphogenesis || multicellular organismal metabolic process || negative regulation of osteoclast differentiation || response to wounding || regulation of organic acid transport || positive regulation of cell killing || regulation of signal transduction by p53 class mediator || morphogenesis of a branching epithelium || positive regulation of fatty acid transport || skeletal muscle tissue development || negative regulation of innate immune response || receptor-mediated endocytosis || ureteric bud morphogenesis || regulation of osteoclast differentiation || cell morphogenesis involved in neuron differentiation || cell recognition || ossification || positive regulation of natural killer cell mediated cytotoxicity || regulation of leukocyte mediated immunity || positive regulation of icosanoid secretion || positive regulation of arachidonic acid secretion || single-multicellular organism process || defense response || ureteric bud development || oxidative stress-induced premature senescence || extracellular matrix organization || regulation of localization || phagocytosis, recognition || positive regulation of immune response || negative regulation of angiogenesis || glycosaminoglycan metabolic process || positive regulation of lipid transport || muscle fiber development || urogenital system development || single-organism developmental process || calcium-dependent cell-cell adhesion || positive regulation of secretion || renal system development || neuron projection development || positive regulation of plasminogen activation || taxis || regulation of cell killing || regulation of response to stimulus || chemical homeostasis within a tissue || regulation of arachidonic acid secretion || reactive oxygen species metabolic process || positive regulation of immune system process || branching involved in ureteric bud morphogenesis || regulation of cytokine biosynthetic process || regulation of fatty acid transport || positive regulation of transport || positive regulation of biological process || glomerulus development || wound healing involved in inflammatory response || collagen metabolic process || regulation of protein processing || response to stimulus || regulation of immune response || regulation of natural killer cell mediated cytotoxicity || prostate gland development || synapse organization || regulation of plasminogen activation || cell adhesion || positive regulation of signal transduction by p53 class mediator || Wnt receptor signaling pathway || regulation of response to DNA damage stimulus || regulation of lymphocyte mediated immunity || cellular senescence || regulation of lipid transport || regulation of establishment of protein localization || regulation of leukocyte mediated cytotoxicity || regulation of anion transport || positive regulation of protein processing |
| Biological Process (BP) |
single-organism process |
0.2639 |
0.3316 |
-- |
INHERITED FROM: multicellular organismal macromolecule metabolic process || surfactant homeostasis || morphogenesis of a branching epithelium || natural killer cell activation || cytokine production || cell activation || skeletal muscle tissue development || complement activation, lectin pathway || extracellular structure organization || ureteric bud morphogenesis || cell morphogenesis involved in neuron differentiation || cell recognition || axonogenesis || ossification || cell-matrix adhesion || motor neuron axon guidance || single-multicellular organism process || cell aging || glomerular basement membrane development || ureteric bud development || oxidative stress-induced premature senescence || extracellular matrix organization || phagocytosis, recognition || system development || bone mineralization || replicative senescence || innate immune response activating cell surface receptor signaling pathway || muscle fiber development || urogenital system development || collagen catabolic process || single-organism developmental process || nephron development || calcium-dependent cell-cell adhesion || renal system development || gland morphogenesis || prostate gland morphogenesis || neuron projection development || chemical homeostasis within a tissue || cellular response to oxidative stress || branching involved in ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || biomineral tissue development || stress-induced premature senescence || multicellular organismal catabolic process || glomerulus development || collagen metabolic process || extracellular matrix disassembly || axon guidance || prostate gland development || synapse organization || prostate gland epithelium morphogenesis || cell adhesion || multicellular organismal metabolic process || Wnt receptor signaling pathway || cellular senescence |
| Biological Process (BP) |
macromolecule metabolic process |
1 |
0.4634 |
-- |
INHERITED FROM: multicellular organismal macromolecule metabolic process || aminoglycan catabolic process || collagen metabolic process || complement activation, lectin pathway || glycosaminoglycan catabolic process || glycosaminoglycan metabolic process || collagen catabolic process |
| Biological Process (BP) |
metabolic process |
1 |
0.2411 |
-- |
INHERITED FROM: multicellular organismal macromolecule metabolic process || complement activation, lectin pathway || glycosaminoglycan catabolic process || reactive oxygen species metabolic process || multicellular organismal catabolic process || aminoglycan catabolic process || collagen metabolic process || multicellular organismal metabolic process || glycosaminoglycan metabolic process || collagen catabolic process |
| Biological Process (BP) |
organic substance metabolic process |
1 |
0.2676 |
-- |
INHERITED FROM: multicellular organismal macromolecule metabolic process || complement activation, lectin pathway || glycosaminoglycan catabolic process || aminoglycan catabolic process || collagen metabolic process || glycosaminoglycan metabolic process || collagen catabolic process |
| Biological Process (BP) |
positive regulation of cell communication |
0.04325 |
1.377 |
-- |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
positive regulation of signaling |
0.4066 |
1.377 |
-- |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
regulation of signal transduction |
1 |
1.119 |
-- |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8539 |
-- |
INHERITED FROM: surfactant homeostasis || chemical homeostasis within a tissue |
| Biological Process (BP) |
regulation of defense response |
0.6518 |
1.658 |
-- |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || innate immune response activating cell surface receptor signaling pathway || positive regulation of natural killer cell mediated immunity || negative regulation of innate immune response || positive regulation of natural killer cell mediated cytotoxicity || regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1 |
1.066 |
-- |
INHERITED FROM: regulation of cytokine biosynthetic process |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
1 |
1.009 |
-- |
INHERITED FROM: regulation of cytokine biosynthetic process |
| Biological Process (BP) |
response to nitrogen compound |
0.7682 |
1.377 |
-- |
INHERITED FROM: response to ATP || response to purine-containing compound |
| Biological Process (BP) |
regulation of transport |
0.03569 |
1.155 |
-- |
INHERITED FROM: positive regulation of icosanoid secretion || regulation of fatty acid transport || regulation of organic acid transport || regulation of arachidonic acid secretion || positive regulation of transport || positive regulation of arachidonic acid secretion || regulation of phagocytosis || regulation of anion transport || positive regulation of organic acid transport || positive regulation of fatty acid transport || positive regulation of ion transport || positive regulation of cytokine secretion || positive regulation of secretion || regulation of icosanoid secretion || positive regulation of protein secretion || positive regulation of lipid transport || regulation of lipid transport |
| Biological Process (BP) |
cellular process |
1 |
0.1415 |
-- |
INHERITED FROM: natural killer cell activation || cell activation || extracellular structure organization || cell morphogenesis involved in neuron differentiation || cell recognition || axonogenesis || cell-matrix adhesion || motor neuron axon guidance || cell aging || glomerular basement membrane development || oxidative stress-induced premature senescence || extracellular matrix organization || phagocytosis, recognition || replicative senescence || innate immune response activating cell surface receptor signaling pathway || muscle fiber development || calcium-dependent cell-cell adhesion || neuron projection development || reactive oxygen species metabolic process || cellular response to oxidative stress || stress-induced premature senescence || extracellular matrix disassembly || axon guidance || synapse organization || cell adhesion || Wnt receptor signaling pathway || cellular senescence |
| Biological Process (BP) |
leukocyte activation |
0.1174 |
1.553 |
-- |
INHERITED FROM: natural killer cell activation |
| Biological Process (BP) |
lymphocyte activation |
0.5404 |
1.699 |
-- |
INHERITED FROM: natural killer cell activation |
| Biological Process (BP) |
regulation of multicellular organismal development |
1 |
1.268 |
-- |
INHERITED FROM: negative regulation of angiogenesis || regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
regulation of vasculature development |
0.04698 |
1.854 |
-- |
INHERITED FROM: negative regulation of angiogenesis |
| Biological Process (BP) |
cell-cell adhesion |
0.8945 |
2.222 |
-- |
INHERITED FROM: calcium-dependent cell-cell adhesion |
| Biological Process (BP) |
response to chemical stimulus |
1 |
0.8861 |
-- |
INHERITED FROM: response to purine-containing compound || oxidative stress-induced premature senescence || cellular response to oxidative stress || chemotaxis || axon guidance || response to ATP || motor neuron axon guidance || response to organophosphorus |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0.95 |
1.301 |
-- |
INHERITED FROM: positive regulation of protein processing || positive regulation of plasminogen activation |
| Biological Process (BP) |
response to stress |
0.1181 |
0.8125 |
-- |
INHERITED FROM: response to wounding || wound healing involved in inflammatory response || complement activation, lectin pathway || oxidative stress-induced premature senescence || cellular response to oxidative stress || stress-induced premature senescence || cellular senescence || cellular defense response || defense response |
| Biological Process (BP) |
cell projection morphogenesis |
0.002401 |
1.854 |
-- |
INHERITED FROM: motor neuron axon guidance || axonogenesis || axon guidance |
| Biological Process (BP) |
neuron projection morphogenesis |
0.002835 |
2 |
-- |
INHERITED FROM: motor neuron axon guidance || axonogenesis || axon guidance |
| Biological Process (BP) |
cell part morphogenesis |
0.003005 |
1.796 |
-- |
INHERITED FROM: motor neuron axon guidance || axonogenesis || axon guidance |
| Biological Process (BP) |
striated muscle tissue development |
0.0196 |
1.745 |
-- |
INHERITED FROM: skeletal muscle tissue development |
| Biological Process (BP) |
skeletal muscle organ development |
0.08896 |
2.398 |
-- |
INHERITED FROM: skeletal muscle tissue development |
| Biological Process (BP) |
neuron differentiation |
0.06113 |
1.658 |
-- |
INHERITED FROM: axonogenesis || cell morphogenesis involved in neuron differentiation || neuron projection development || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
transport |
1 |
0.7747 |
-- |
INHERITED FROM: phagocytosis, recognition || endocytosis || receptor-mediated endocytosis |
| Biological Process (BP) |
establishment of localization |
1 |
0.7696 |
-- |
INHERITED FROM: phagocytosis, recognition || endocytosis || receptor-mediated endocytosis |
| Biological Process (BP) |
single-organism transport |
1 |
0.8013 |
-- |
INHERITED FROM: phagocytosis, recognition |
| Biological Process (BP) |
organonitrogen compound metabolic process |
1 |
0.699 |
-- |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan metabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
aminoglycan metabolic process |
0.001392 |
2 |
-- |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process || glycosaminoglycan metabolic process |
| Biological Process (BP) |
catabolic process |
1 |
0.7852 |
-- |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
macromolecule catabolic process |
1 |
1.252 |
-- |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
regulation of myeloid leukocyte differentiation |
0.005645 |
2.699 |
-- |
INHERITED FROM: negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation || regulation of osteoclast differentiation |
| Biological Process (BP) |
negative regulation of myeloid cell differentiation |
0.002286 |
2.699 |
-- |
INHERITED FROM: negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
negative regulation of cell differentiation |
0.9972 |
1.745 |
-- |
INHERITED FROM: negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
positive regulation of leukocyte mediated immunity |
0.01332 |
2.222 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.1082 |
1.237 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || Wnt receptor signaling pathway |
| Biological Process (BP) |
signaling |
0.1683 |
0.8416 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || Wnt receptor signaling pathway |
| Biological Process (BP) |
cell communication |
0.2112 |
0.8477 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || Wnt receptor signaling pathway |
| Biological Process (BP) |
single organism signaling |
0.2637 |
0.8601 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || Wnt receptor signaling pathway |
| Biological Process (BP) |
positive regulation of innate immune response |
0.006506 |
2.699 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
immune response-regulating cell surface receptor signaling pathway |
0.001374 |
2.222 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
innate immune response-activating signal transduction |
0.01097 |
2.699 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
immune response-activating cell surface receptor signaling pathway |
0.07025 |
2.222 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
activation of innate immune response |
0.7411 |
2.699 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
immune response-activating signal transduction |
1 |
2.097 |
-- |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
complement activation |
0.05925 |
2.222 |
-- |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
primary metabolic process |
1 |
0.2976 |
-- |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
morphogenesis of a branching structure |
0.002953 |
2 |
-- |
INHERITED FROM: branching involved in ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || morphogenesis of a branching epithelium |
| Biological Process (BP) |
branching morphogenesis of an epithelial tube |
0.001472 |
2.097 |
-- |
INHERITED FROM: branching involved in ureteric bud morphogenesis |
| Biological Process (BP) |
anatomical structure development |
1 |
0.7212 |
-- |
INHERITED FROM: ureteric bud development || renal system development || glomerulus development || morphogenesis of a branching epithelium || gland morphogenesis || prostate gland morphogenesis || neuron projection development || system development || axon guidance || skeletal muscle tissue development || prostate gland development || prostate gland epithelium morphogenesis || bone mineralization || ureteric bud morphogenesis || cell morphogenesis involved in neuron differentiation || axonogenesis || branching involved in ureteric bud morphogenesis || muscle fiber development || urogenital system development || branching involved in prostate gland morphogenesis || motor neuron axon guidance || biomineral tissue development || nephron development || glomerular basement membrane development |
| Biological Process (BP) |
multicellular organismal development |
0.8659 |
0.7496 |
-- |
INHERITED FROM: ureteric bud development || renal system development || glomerulus development || gland morphogenesis || prostate gland morphogenesis || neuron projection development || system development || axon guidance || skeletal muscle tissue development || prostate gland development || prostate gland epithelium morphogenesis || bone mineralization || ureteric bud morphogenesis || cell morphogenesis involved in neuron differentiation || axonogenesis || branching involved in ureteric bud morphogenesis || urogenital system development || branching involved in prostate gland morphogenesis || motor neuron axon guidance || biomineral tissue development || nephron development || glomerular basement membrane development |
| Biological Process (BP) |
response to stimulus |
8.447e-06 |
0.5498 |
Least Informative |
DIRECT |
| Biological Process (BP) |
multicellular organismal process |
9.287e-10 |
0.6091 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
6.858e-06 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
1 |
0.5317 |
Least Informative |
INHERITED FROM: positive regulation of response to DNA damage stimulus || positive regulation of cytokine secretion || regulation of osteoclast differentiation || positive regulation of DNA damage response, signal transduction by p53 class mediator || negative regulation of myeloid leukocyte differentiation || regulation of cytokine biosynthetic process || regulation of DNA damage response, signal transduction by p53 class mediator || regulation of phagocytosis || negative regulation of osteoclast differentiation || positive regulation of signal transduction by p53 class mediator || Wnt receptor signaling pathway || positive regulation of protein secretion || regulation of response to DNA damage stimulus || innate immune response activating cell surface receptor signaling pathway || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
regulation of metabolic process |
1 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of protein processing || positive regulation of plasminogen activation || regulation of plasminogen activation || regulation of cytokine biosynthetic process || positive regulation of protein processing |
| Biological Process (BP) |
cellular component organization or biogenesis |
1 |
0.6536 |
Least Informative |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || extracellular matrix organization || axonogenesis || extracellular matrix disassembly || neuron projection development || axon guidance || synapse organization || motor neuron axon guidance || glomerular basement membrane development || extracellular structure organization |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5376 |
Least Informative |
INHERITED FROM: multicellular organismal macromolecule metabolic process || collagen metabolic process || multicellular organismal metabolic process || collagen catabolic process || multicellular organismal catabolic process |
| Biological Process (BP) |
single-organism cellular process |
0.7781 |
0.3915 |
Least Informative |
INHERITED FROM: natural killer cell activation || cell activation || neuron projection development || extracellular structure organization || cell morphogenesis involved in neuron differentiation || cell recognition || axonogenesis || cellular response to oxidative stress || cell-matrix adhesion || motor neuron axon guidance || cell aging || stress-induced premature senescence || glomerular basement membrane development || oxidative stress-induced premature senescence || extracellular matrix organization || extracellular matrix disassembly || phagocytosis, recognition || axon guidance || synapse organization || cell adhesion || Wnt receptor signaling pathway || replicative senescence || innate immune response activating cell surface receptor signaling pathway || cellular senescence || muscle fiber development || calcium-dependent cell-cell adhesion |
| Biological Process (BP) |
localization |
1 |
0.6946 |
Least Informative |
INHERITED FROM: phagocytosis, recognition || endocytosis || receptor-mediated endocytosis |
| Biological Process (BP) |
nitrogen compound metabolic process |
1 |
0.5171 |
Least Informative |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process || glycosaminoglycan metabolic process |
| Biological Process (BP) |
protein metabolic process |
1 |
0.6383 |
Least Informative |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
multi-organism process |
0.0009252 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
immune system process |
4.455e-09 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
0.0002704 |
0.9914 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
1.91e-05 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
0.0001983 |
0.7645 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0.8155 |
0.9066 |
Moderately Informative |
INHERITED FROM: positive regulation of response to DNA damage stimulus || positive regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of cytokine secretion || positive regulation of signal transduction by p53 class mediator || positive regulation of protein secretion |
| Biological Process (BP) |
cellular response to chemical stimulus |
1 |
1.097 |
Moderately Informative |
INHERITED FROM: oxidative stress-induced premature senescence || cellular response to oxidative stress |
| Biological Process (BP) |
anatomical structure morphogenesis |
1 |
1.036 |
Moderately Informative |
INHERITED FROM: ureteric bud morphogenesis || morphogenesis of a branching epithelium || cell morphogenesis involved in neuron differentiation || gland morphogenesis || axonogenesis || prostate gland morphogenesis || branching involved in ureteric bud morphogenesis || axon guidance || branching involved in prostate gland morphogenesis || motor neuron axon guidance || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
tissue development |
0.2616 |
1.143 |
Moderately Informative |
INHERITED FROM: ureteric bud morphogenesis || morphogenesis of a branching epithelium || branching involved in ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || skeletal muscle tissue development || prostate gland epithelium morphogenesis || biomineral tissue development || bone mineralization |
| Biological Process (BP) |
reproduction |
0.6527 |
1.097 |
Moderately Informative |
INHERITED FROM: prostate gland morphogenesis || branching involved in prostate gland morphogenesis || prostate gland development || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
regulation of cellular component organization |
1 |
1.18 |
Moderately Informative |
INHERITED FROM: regulation of phagocytosis |
| Biological Process (BP) |
cell differentiation |
1 |
1.009 |
Moderately Informative |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || neuron projection development || muscle fiber development || axon guidance || motor neuron axon guidance |
| Biological Process (BP) |
nervous system development |
1 |
1.194 |
Moderately Informative |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || neuron projection development || axon guidance || motor neuron axon guidance |
| Biological Process (BP) |
regulation of signaling |
1 |
1.076 |
Moderately Informative |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
regulation of cell communication |
1 |
1.066 |
Moderately Informative |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator || regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
homeostatic process |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: surfactant homeostasis || chemical homeostasis within a tissue |
| Biological Process (BP) |
regulation of protein metabolic process |
0.5272 |
1.119 |
Moderately Informative |
INHERITED FROM: regulation of cytokine biosynthetic process || regulation of plasminogen activation || regulation of protein processing || positive regulation of protein processing || positive regulation of plasminogen activation |
| Biological Process (BP) |
regulation of biosynthetic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of cytokine biosynthetic process |
| Biological Process (BP) |
regulation of cellular metabolic process |
1 |
0.7905 |
Moderately Informative |
INHERITED FROM: regulation of cytokine biosynthetic process |
| Biological Process (BP) |
cellular response to stress |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: cellular response to oxidative stress || stress-induced premature senescence || cellular senescence || oxidative stress-induced premature senescence |
| Biological Process (BP) |
response to oxygen-containing compound |
0.8226 |
1.108 |
Moderately Informative |
INHERITED FROM: response to ATP |
| Biological Process (BP) |
organ development |
0.09948 |
0.9355 |
Moderately Informative |
INHERITED FROM: glomerulus development || gland morphogenesis || prostate gland morphogenesis || skeletal muscle tissue development || prostate gland development || prostate gland epithelium morphogenesis || bone mineralization || branching involved in prostate gland morphogenesis || biomineral tissue development || nephron development || glomerular basement membrane development |
| Biological Process (BP) |
regulation of multicellular organismal process |
0.2307 |
0.9666 |
Moderately Informative |
INHERITED FROM: positive regulation of interferon-gamma production || positive regulation of cytokine secretion || regulation of cytokine production || negative regulation of osteoclast differentiation || negative regulation of angiogenesis || regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation || regulation of cytokine biosynthetic process |
| Biological Process (BP) |
regulation of developmental process |
1 |
1.155 |
Moderately Informative |
INHERITED FROM: negative regulation of angiogenesis || regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
response to organic substance |
1 |
1.018 |
Moderately Informative |
INHERITED FROM: response to purine-containing compound || response to ATP || response to organophosphorus |
| Biological Process (BP) |
response to endogenous stimulus |
1 |
1.237 |
Moderately Informative |
INHERITED FROM: response to purine-containing compound || response to ATP |
| Biological Process (BP) |
positive regulation of metabolic process |
0.9915 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of protein processing || positive regulation of plasminogen activation |
| Biological Process (BP) |
regulation of gene expression |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of plasminogen activation || regulation of protein processing || positive regulation of protein processing || positive regulation of plasminogen activation |
| Biological Process (BP) |
carbohydrate derivative metabolic process |
1 |
1.018 |
Moderately Informative |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan metabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
organic substance catabolic process |
1 |
0.8297 |
Moderately Informative |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
negative regulation of cellular process |
1 |
0.9355 |
Moderately Informative |
INHERITED FROM: negative regulation of myeloid leukocyte differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
signal transduction |
0.1817 |
0.9914 |
Moderately Informative |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || Wnt receptor signaling pathway |
| Biological Process (BP) |
biological adhesion |
0 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
defense response |
4.008e-15 |
1.357 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of immune response |
4.117e-09 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
response to wounding |
2.794e-05 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine production |
1.68e-10 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transport |
4.461e-10 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of immune system process |
3.718e-08 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of response to stress |
1.189e-06 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
cell activation |
0.0004628 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
response to oxidative stress |
0.09559 |
1.469 |
Informative |
INHERITED FROM: oxidative stress-induced premature senescence || cellular response to oxidative stress |
| Biological Process (BP) |
regulation of protein localization |
0.326 |
1.585 |
Informative |
INHERITED FROM: regulation of establishment of protein localization || positive regulation of protein secretion || positive regulation of cytokine secretion |
| Biological Process (BP) |
epithelium development |
1 |
1.377 |
Informative |
INHERITED FROM: ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || morphogenesis of a branching epithelium || prostate gland epithelium morphogenesis || branching involved in ureteric bud morphogenesis |
| Biological Process (BP) |
tissue morphogenesis |
0.8778 |
1.585 |
Informative |
INHERITED FROM: ureteric bud morphogenesis || branching involved in prostate gland morphogenesis || branching involved in ureteric bud morphogenesis || morphogenesis of a branching epithelium || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
tube development |
0.01604 |
1.62 |
Informative |
INHERITED FROM: ureteric bud morphogenesis || ureteric bud development || branching involved in ureteric bud morphogenesis |
| Biological Process (BP) |
organ morphogenesis |
1 |
1.523 |
Informative |
INHERITED FROM: branching involved in prostate gland morphogenesis || prostate gland epithelium morphogenesis || prostate gland morphogenesis |
| Biological Process (BP) |
reproductive system development |
0.9366 |
1.658 |
Informative |
INHERITED FROM: branching involved in prostate gland morphogenesis || prostate gland development || prostate gland morphogenesis || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
developmental process involved in reproduction |
1 |
1.469 |
Informative |
INHERITED FROM: branching involved in prostate gland morphogenesis || prostate gland development || prostate gland morphogenesis || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
anatomical structure homeostasis |
0.05683 |
1.745 |
Informative |
INHERITED FROM: chemical homeostasis within a tissue || surfactant homeostasis |
| Biological Process (BP) |
multicellular organismal homeostasis |
0.1748 |
1.745 |
Informative |
INHERITED FROM: chemical homeostasis within a tissue || surfactant homeostasis |
| Biological Process (BP) |
cellular component morphogenesis |
0.1837 |
1.495 |
Informative |
INHERITED FROM: cell morphogenesis involved in neuron differentiation || axonogenesis || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.9698 |
1.585 |
Informative |
INHERITED FROM: negative regulation of innate immune response |
| Biological Process (BP) |
regulation of cell development |
1 |
1.469 |
Informative |
INHERITED FROM: regulation of osteoclast differentiation || negative regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
positive regulation of signal transduction |
0.4783 |
1.377 |
Informative |
INHERITED FROM: positive regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of signal transduction by p53 class mediator |
| Biological Process (BP) |
locomotion |
0.001587 |
1.444 |
Informative |
INHERITED FROM: taxis || chemotaxis || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
response to external stimulus |
0.5347 |
1.319 |
Informative |
INHERITED FROM: taxis || chemotaxis || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
regulation of immune effector process |
0.001291 |
1.658 |
Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of immune effector process || positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity || regulation of leukocyte mediated immunity || regulation of natural killer cell mediated immunity || regulation of leukocyte mediated cytotoxicity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
response to organic cyclic compound |
0.273 |
1.523 |
Informative |
INHERITED FROM: response to ATP || response to purine-containing compound |
| Biological Process (BP) |
response to organic nitrogen |
0.3206 |
1.495 |
Informative |
INHERITED FROM: response to ATP || response to purine-containing compound |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
1 |
1.585 |
Informative |
INHERITED FROM: positive regulation of interferon-gamma production |
| Biological Process (BP) |
regulation of secretion |
0.00114 |
1.658 |
Informative |
INHERITED FROM: positive regulation of icosanoid secretion || positive regulation of cytokine secretion || positive regulation of secretion || regulation of icosanoid secretion || regulation of arachidonic acid secretion || positive regulation of arachidonic acid secretion || positive regulation of protein secretion |
| Biological Process (BP) |
regulation of ion transport |
0.09135 |
1.585 |
Informative |
INHERITED FROM: positive regulation of icosanoid secretion || regulation of icosanoid secretion || regulation of arachidonic acid secretion || positive regulation of arachidonic acid secretion || positive regulation of fatty acid transport || positive regulation of ion transport || regulation of anion transport || regulation of fatty acid transport |
| Biological Process (BP) |
cellular component disassembly |
0.006596 |
1.745 |
Informative |
INHERITED FROM: extracellular matrix disassembly |
| Biological Process (BP) |
gland development |
0.2165 |
1.658 |
Informative |
INHERITED FROM: gland morphogenesis || branching involved in prostate gland morphogenesis || prostate gland development || prostate gland morphogenesis || prostate gland epithelium morphogenesis |
| Biological Process (BP) |
negative regulation of developmental process |
0.5125 |
1.699 |
Informative |
INHERITED FROM: negative regulation of angiogenesis || negative regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1 |
1.42 |
Informative |
INHERITED FROM: negative regulation of angiogenesis |
| Biological Process (BP) |
positive regulation of protein metabolic process |
0.07188 |
1.469 |
Informative |
INHERITED FROM: positive regulation of protein processing || positive regulation of plasminogen activation |
| Biological Process (BP) |
muscle structure development |
0.6317 |
1.62 |
Informative |
INHERITED FROM: skeletal muscle tissue development || muscle fiber development |
| Biological Process (BP) |
muscle tissue development |
0.2442 |
1.699 |
Informative |
INHERITED FROM: skeletal muscle tissue development |
| Biological Process (BP) |
generation of neurons |
0.4426 |
1.469 |
Informative |
INHERITED FROM: axonogenesis || cell morphogenesis involved in neuron differentiation || neuron projection development || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
cell projection organization |
0.02474 |
1.553 |
Informative |
INHERITED FROM: axonogenesis || neuron projection development || motor neuron axon guidance || axon guidance |
| Biological Process (BP) |
vesicle-mediated transport |
0.005702 |
1.495 |
Informative |
INHERITED FROM: phagocytosis, recognition || endocytosis || receptor-mediated endocytosis |
| Biological Process (BP) |
carbohydrate derivative catabolic process |
0.482 |
1.553 |
Informative |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
organonitrogen compound catabolic process |
0.9072 |
1.268 |
Informative |
INHERITED FROM: aminoglycan catabolic process || glycosaminoglycan catabolic process |
| Biological Process (BP) |
immune response |
0.003638 |
1.495 |
Informative |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
immune effector process |
0.9479 |
1.658 |
Informative |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
cell adhesion |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
ossification |
6.427e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell killing |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
0 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
extracellular matrix organization |
6.976e-14 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein processing |
3.99e-13 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
multicellular organismal metabolic process |
1.198e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of secretion |
2.839e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
aminoglycan catabolic process |
8.163e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
chemical homeostasis within a tissue |
6.331e-06 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
axonogenesis |
8.484e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to purine-containing compound |
5.182e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of ion transport |
8.201e-05 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching epithelium |
0.0001188 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
glycosaminoglycan metabolic process |
0.0004185 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
muscle fiber development |
0.0004857 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
chemotaxis |
0.0005829 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine biosynthetic process |
0.0006895 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of immune effector process |
0.0007895 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to stress |
0.00232 |
1.921 |
Highly Informative |
INHERITED FROM: regulation of response to DNA damage stimulus || positive regulation of DNA damage response, signal transduction by p53 class mediator || regulation of DNA damage response, signal transduction by p53 class mediator || positive regulation of response to DNA damage stimulus |
| Biological Process (BP) |
kidney development |
0.01287 |
2 |
Highly Informative |
INHERITED FROM: nephron development || glomerulus development || glomerular basement membrane development |
| Biological Process (BP) |
epithelial tube morphogenesis |
0.001986 |
1.854 |
Highly Informative |
INHERITED FROM: ureteric bud morphogenesis || branching involved in ureteric bud morphogenesis |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
0.03501 |
1.854 |
Highly Informative |
INHERITED FROM: regulation of phagocytosis |
| Biological Process (BP) |
regulation of protein secretion |
0.005057 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of cytokine secretion || positive regulation of protein secretion |
| Biological Process (BP) |
positive regulation of protein transport |
0.2661 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of protein secretion || positive regulation of cytokine secretion |
| Biological Process (BP) |
negative regulation of immune system process |
0.01785 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of innate immune response |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
0.1873 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of osteoclast differentiation || negative regulation of myeloid leukocyte differentiation || regulation of osteoclast differentiation |
| Biological Process (BP) |
regulation of innate immune response |
0.01035 |
2.097 |
Highly Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || negative regulation of innate immune response || positive regulation of natural killer cell mediated cytotoxicity || innate immune response activating cell surface receptor signaling pathway || regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
positive regulation of cytokine production |
0.3045 |
1.921 |
Highly Informative |
INHERITED FROM: positive regulation of interferon-gamma production |
| Biological Process (BP) |
regulation of angiogenesis |
0.03226 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of angiogenesis |
| Biological Process (BP) |
aging |
0.01637 |
2 |
Highly Informative |
INHERITED FROM: cell aging || stress-induced premature senescence || oxidative stress-induced premature senescence || cellular senescence || replicative senescence |
| Biological Process (BP) |
muscle organ development |
0.08462 |
2 |
Highly Informative |
INHERITED FROM: skeletal muscle tissue development |
| Biological Process (BP) |
phagocytosis |
0.005039 |
2 |
Highly Informative |
INHERITED FROM: phagocytosis, recognition |
| Biological Process (BP) |
regulation of leukocyte differentiation |
0.47 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of myeloid leukocyte differentiation || regulation of osteoclast differentiation || negative regulation of osteoclast differentiation |
| Biological Process (BP) |
wound healing |
0.02416 |
2 |
Highly Informative |
INHERITED FROM: wound healing involved in inflammatory response |
| Biological Process (BP) |
inflammatory response |
0.001363 |
1.921 |
Highly Informative |
INHERITED FROM: wound healing involved in inflammatory response |
| Biological Process (BP) |
activation of immune response |
0.01181 |
1.921 |
Highly Informative |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway || complement activation, lectin pathway |
| Biological Process (BP) |
immune response-regulating signaling pathway |
0.009324 |
2 |
Highly Informative |
INHERITED FROM: innate immune response activating cell surface receptor signaling pathway |
| Biological Process (BP) |
humoral immune response |
0.02594 |
2 |
Highly Informative |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
innate immune response |
1 |
1.921 |
Highly Informative |
INHERITED FROM: complement activation, lectin pathway |
| Biological Process (BP) |
protein activation cascade |
0.001249 |
2.222 |
Highly Informative |
INHERITED FROM: complement activation, lectin pathway |
| Molecular Function (MF) |
carbohydrate binding |
0 |
1.9 |
-- |
DIRECT |
| Molecular Function (MF) |
Gram-negative bacterial cell surface binding |
0.0008123 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
bacterial cell surface binding |
0.0001492 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
galactose binding |
1.302e-07 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
cell surface binding |
2.397e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
identical protein binding |
6.55e-06 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
carbohydrate derivative binding |
0 |
1.833 |
-- |
DIRECT |
| Molecular Function (MF) |
protein-lipid complex binding |
1.466e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
signal transducer activity |
2.191e-08 |
1.599 |
-- |
DIRECT |
| Molecular Function (MF) |
heparin binding |
3.085e-07 |
2.076 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
1 |
0 |
-- |
INHERITED FROM: protein dimerization activity || calcium ion binding || carbohydrate binding || sulfur compound binding || receptor activity || glycosaminoglycan binding || heparin binding || extracellular matrix structural constituent || low-density lipoprotein particle binding || signal transducer activity || pattern recognition receptor activity || molecular transducer activity || cargo receptor activity || hyaluronic acid binding || low-density lipoprotein receptor activity || galactose binding || protein-lipid complex binding || identical protein binding || receptor binding || Gram-negative bacterial cell surface binding || cell surface binding || structural molecule activity || natural killer cell lectin-like receptor binding || carbohydrate derivative binding || bacterial cell surface binding || phospholipase binding || binding || protein homodimerization activity |
| Molecular Function (MF) |
signaling receptor activity |
1 |
1.724 |
-- |
INHERITED FROM: pattern recognition receptor activity |
| Molecular Function (MF) |
ion binding |
1 |
0.8334 |
-- |
INHERITED FROM: heparin binding || calcium ion binding |
| Molecular Function (MF) |
metal ion binding |
0.05133 |
1.134 |
-- |
INHERITED FROM: calcium ion binding |
| Molecular Function (MF) |
binding |
0 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
structural molecule activity |
6.127e-05 |
1.201 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
anion binding |
0.5616 |
1.076 |
Moderately Informative |
INHERITED FROM: heparin binding |
| Molecular Function (MF) |
cation binding |
0.08412 |
1.099 |
Moderately Informative |
INHERITED FROM: calcium ion binding |
| Molecular Function (MF) |
protein binding |
1 |
0.77 |
Moderately Informative |
INHERITED FROM: receptor binding || protein dimerization activity || phospholipase binding || natural killer cell lectin-like receptor binding || identical protein binding || protein homodimerization activity |
| Molecular Function (MF) |
receptor activity |
0 |
1.637 |
Informative |
DIRECT |
| Molecular Function (MF) |
receptor binding |
0.0001468 |
1.565 |
Informative |
DIRECT |
| Molecular Function (MF) |
protein dimerization activity |
2.254e-05 |
1.637 |
Informative |
DIRECT |
| Molecular Function (MF) |
molecular transducer activity |
2.207e-08 |
1.565 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
0.009466 |
1.679 |
Informative |
INHERITED FROM: phospholipase binding |
| Molecular Function (MF) |
protein homodimerization activity |
2.958e-05 |
1.98 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
calcium ion binding |
3.086e-09 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
sulfur compound binding |
2.151e-06 |
1.833 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
glycosaminoglycan binding |
0.000308 |
1.98 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
monosaccharide binding |
0.5523 |
1.98 |
Highly Informative |
INHERITED FROM: galactose binding |
| Cellular Component (CC) |
extracellular region part |
0 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
plasma membrane part |
0 |
1.036 |
-- |
DIRECT |
| Cellular Component (CC) |
cell periphery |
0 |
0.8256 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane part |
0 |
0.6842 |
-- |
DIRECT |
| Cellular Component (CC) |
cellular_component |
5.368e-10 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
collagen |
0 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
basement membrane |
2.053e-13 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
endoplasmic reticulum lumen |
1.496e-08 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
basal lamina |
6.792e-05 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
1 |
0.3713 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
organelle lumen |
1 |
1.023 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
membrane-enclosed lumen |
1 |
0.9395 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
intracellular part |
1 |
0.1266 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
intracellular |
1 |
0.1266 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
organelle |
1 |
0.1836 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
intracellular organelle |
1 |
0.1875 |
-- |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
nuclear lumen |
1 |
1.161 |
-- |
INHERITED FROM: nucleolar part || granular component |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6225 |
-- |
INHERITED FROM: nucleolar part || granular component |
| Cellular Component (CC) |
nucleus |
1 |
0.7857 |
-- |
INHERITED FROM: nucleolar part || granular component |
| Cellular Component (CC) |
cell part |
1 |
0.08068 |
-- |
INHERITED FROM: plasma membrane || endoplasmic reticulum lumen || granular component || cell periphery || external side of plasma membrane || plasma membrane part || nucleolar part || integral to plasma membrane || cell surface |
| Cellular Component (CC) |
cell |
1 |
0.08068 |
-- |
INHERITED FROM: plasma membrane || endoplasmic reticulum lumen || granular component || cell periphery || external side of plasma membrane || plasma membrane part || nucleolar part || integral to plasma membrane || cell surface |
| Cellular Component (CC) |
endoplasmic reticulum part |
0.05073 |
1.365 |
-- |
INHERITED FROM: endoplasmic reticulum lumen |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: endoplasmic reticulum lumen |
| Cellular Component (CC) |
nucleolus |
0.2459 |
1.763 |
-- |
INHERITED FROM: granular component || nucleolar part |
| Cellular Component (CC) |
membrane |
0 |
0.5731 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
intracellular organelle part |
1 |
0.3893 |
Least Informative |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6225 |
Least Informative |
INHERITED FROM: nucleolar part || granular component |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: endoplasmic reticulum lumen |
| Cellular Component (CC) |
extracellular region |
0 |
0.9505 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
plasma membrane |
0 |
0.9734 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle lumen |
1 |
1.023 |
Moderately Informative |
INHERITED FROM: nucleolar part || endoplasmic reticulum lumen || granular component |
| Cellular Component (CC) |
nuclear part |
1 |
0.9505 |
Moderately Informative |
INHERITED FROM: nucleolar part || granular component |
| Cellular Component (CC) |
intrinsic to membrane |
1 |
1.18 |
Moderately Informative |
INHERITED FROM: integral to plasma membrane |
| Cellular Component (CC) |
endoplasmic reticulum |
0.08534 |
1.127 |
Moderately Informative |
INHERITED FROM: endoplasmic reticulum lumen |
| Cellular Component (CC) |
cell surface |
0 |
1.542 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix |
0 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
synapse |
0.652 |
1.462 |
Informative |
INHERITED FROM: neuromuscular junction |
| Cellular Component (CC) |
integral to membrane |
0.02595 |
1.286 |
Informative |
INHERITED FROM: integral to plasma membrane |
| Cellular Component (CC) |
intrinsic to plasma membrane |
0.8844 |
1.696 |
Informative |
INHERITED FROM: integral to plasma membrane |
| Cellular Component (CC) |
proteinaceous extracellular matrix |
0 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
external side of plasma membrane |
0 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
integral to plasma membrane |
1.234e-06 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix part |
0 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
nucleolar part |
4.002e-10 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
neuromuscular junction |
0.0001289 |
2.241 |
Highly Informative |
DIRECT |