SUPERFAMILY 1.75 HMM library and genome assignments server

C-type lectin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Families:   C-type lectin domain [ 56437] (28)
  Aerolysin/Pertussis toxin (APT) domain [ 56467] (2)
  Invasin/intimin cell-adhesion fragment, C-terminal domain [ 56472] (2)
  Link domain [ 56477] (2)
  Endostatin [ 56480] (2)
  Noncollagenous (NC1) domain of collagen IV [ 75585]
  Sulfatase-modifying factor-like [ 143959] (2)
  Mtd variable domain [ 143964]


Superfamily statistics
Genomes (1,620) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 26,554 39,333 125
Proteins 19,026 31,472 121


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.00042770.00000000001808Least InformativeDirect
Biological Process (BP)positive regulation of biological process0.26280.000000003597Least InformativeInherited
Biological Process (BP)regulation of cellular process0.70331Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.16080.0000000001755Least InformativeInherited
Biological Process (BP)defense response0.00000080260Moderately InformativeDirect
Biological Process (BP)immune system process0.0000015580.00000000000001414Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process0.036260.1897Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.11041Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.088211Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus0.044930.00000000009273Moderately InformativeInherited
Biological Process (BP)multi-organism process0.00000049150.001935Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.0047720.009004Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.26480.9562Moderately InformativeInherited
Biological Process (BP)signal transduction0.038510.05555Moderately InformativeInherited
Biological Process (BP)biological adhesion0.000000000052890InformativeDirect
Biological Process (BP)immune response0.00028020.0001743InformativeDirect
Biological Process (BP)regulation of immune response0.00033590.0000000002956InformativeDirect
Biological Process (BP)regulation of response to wounding0.025070.9331InformativeInherited
Biological Process (BP)negative regulation of developmental process0.00059750.2097InformativeInherited
Biological Process (BP)negative regulation of multicellular organismal process0.0032550.01804InformativeInherited
Biological Process (BP)response to bacterium0.011350.008652InformativeInherited
Biological Process (BP)defense response to other organism0.08740.6061InformativeInherited
Biological Process (BP)regulation of cell proliferation0.0055830.401InformativeInherited
Biological Process (BP)positive regulation of immune system process0.02530.0000000001278InformativeInherited
Biological Process (BP)regulation of defense response0.31790.2575InformativeInherited
Biological Process (BP)cell adhesion0.000000000026230Highly InformativeDirect
Biological Process (BP)regulation of wound healing0.000000011920.000009224Highly InformativeDirect
Biological Process (BP)defense response to bacterium0.00018660.0008513Highly InformativeDirect
Biological Process (BP)ossification0.00019380.000000006457Highly InformativeDirect
Biological Process (BP)positive regulation of response to wounding0.0000047180.1035Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.000000049690.01962Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.00025930.4979Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.00017080.0707Highly InformativeInherited
Biological Process (BP)positive regulation of defense response0.0024780.00001218Highly InformativeInherited
Biological Process (BP)regulation of innate immune response0.0095290.00003937Highly InformativeInherited
Biological Process (BP)immune response-activating signal transduction0.63240.6689Highly InformativeInherited
Molecular Function (MF)binding0.00000000024780Least InformativeDirect
Molecular Function (MF)receptor activity0.000000011070InformativeDirect
Molecular Function (MF)monosaccharide binding10.7603Highly InformativeInherited
Cellular Component (CC)membrane0.0011230Least InformativeInherited
Cellular Component (CC)extracellular region part0.00000760Moderately InformativeDirect
Cellular Component (CC)plasma membrane part0.00014280Moderately InformativeDirect
Cellular Component (CC)cell surface0.000000000036950InformativeDirect
Cellular Component (CC)extracellular matrix0.0000052050InformativeDirect
Cellular Component (CC)side of membrane0.00013520InformativeDirect
Cellular Component (CC)extracellular matrix part0.000031750Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix0.000069410Highly InformativeDirect
Cellular Component (CC)external side of plasma membrane0.00053630Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.00000000001808 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.0000000001755 Least Informative Direct
Biological Process (BP) positive regulation of biological process 0.000000003597 Least Informative Direct
Biological Process (BP) developmental process 0.000007085 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 0.9093 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) defense response 0 Moderately Informative Direct
Biological Process (BP) immune system process 0.00000000000001414 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 0.00000000009273 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.9562 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.2187 Moderately Informative Inherited
Biological Process (BP) reproductive process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.2483 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.002435 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.009004 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.9938 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.6835 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.001935 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.05555 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.1897 Moderately Informative Inherited
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) immune response 0.0001743 Informative Direct
Biological Process (BP) regulation of immune response 0.0000000002956 Informative Direct
Biological Process (BP) positive regulation of immune system process 0.0000000001278 Informative Direct
Biological Process (BP) positive regulation of transport 0.0000002304 Informative Direct
Biological Process (BP) vesicle-mediated transport 0.00005823 Informative Direct
Biological Process (BP) regulation of cytokine production 0.000000001671 Informative Direct
Biological Process (BP) muscle system process 0.000005565 Informative Direct
Biological Process (BP) cellular component movement 0.00001137 Informative Direct
Biological Process (BP) locomotion 0.00003263 Informative Direct
Biological Process (BP) regulation of immune effector process 0.0004719 Informative Direct
Biological Process (BP) regulation of ion transport 0.1534 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of secretion 0.001228 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.6651 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.09654 Informative Inherited
Biological Process (BP) response to oxidative stress 0.5948 Informative Inherited
Biological Process (BP) cell projection organization 0.004215 Informative Inherited
Biological Process (BP) regulation of response to wounding 0.9331 Informative Inherited
Biological Process (BP) gland development 0.2804 Informative Inherited
Biological Process (BP) organ morphogenesis 0.9317 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.2388 Informative Inherited
Biological Process (BP) reproductive structure development 0.8415 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.03726 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.4402 Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.161 Informative Inherited
Biological Process (BP) multicellular organismal homeostasis 0.2936 Informative Inherited
Biological Process (BP) tube development 0.02527 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.2097 Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.003137 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.01804 Informative Inherited
Biological Process (BP) positive regulation of intracellular signal transduction 0.02191 Informative Inherited
Biological Process (BP) defense response to other organism 0.6061 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.3538 Informative Inherited
Biological Process (BP) response to bacterium 0.008652 Informative Inherited
Biological Process (BP) response to lipid 0.2714 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.2993 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.4112 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.401 Informative Inherited
Biological Process (BP) generation of neurons 0.2018 Informative Inherited
Biological Process (BP) sexual reproduction 1 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.9135 Informative Inherited
Biological Process (BP) regulation of defense response 0.2575 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.8977 Informative Inherited
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) regulation of wound healing 0.000009224 Highly Informative Direct
Biological Process (BP) defense response to bacterium 0.0008513 Highly Informative Direct
Biological Process (BP) ossification 0.000000006457 Highly Informative Direct
Biological Process (BP) wound healing 0.0002309 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 0.00001218 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 0.00003937 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) multicellular organismal catabolic process 0.0000000006323 Highly Informative Direct
Biological Process (BP) collagen metabolic process 0.000000002724 Highly Informative Direct
Biological Process (BP) kidney development 0.000000003563 Highly Informative Direct
Biological Process (BP) positive regulation of cytokine production 0.00000001552 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 0.00000006124 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 0.0000009123 Highly Informative Direct
Biological Process (BP) chemical homeostasis within a tissue 0.000004212 Highly Informative Direct
Biological Process (BP) chemotaxis 0.00007832 Highly Informative Direct
Biological Process (BP) cell recognition 0.00008535 Highly Informative Direct
Biological Process (BP) neuron projection development 0.0001285 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.0001315 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.0002276 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.0002551 Highly Informative Direct
Biological Process (BP) glycosaminoglycan metabolic process 0.0003465 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.0003955 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 0.0005283 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.0005739 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0.0005888 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.0009854 Highly Informative Direct
Biological Process (BP) aging 0.0128 Highly Informative Inherited
Biological Process (BP) positive regulation of response to wounding 0.1035 Highly Informative Inherited
Biological Process (BP) regulation of endocytosis 0.001019 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte mediated cytotoxicity 0.1344 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.2709 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.01242 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.4979 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.01962 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.0707 Highly Informative Inherited
Biological Process (BP) cell projection morphogenesis 0.002788 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.001603 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.53 Highly Informative Inherited
Biological Process (BP) positive regulation of lymphocyte mediated immunity 0.2287 Highly Informative Inherited
Biological Process (BP) inflammatory response 0.005836 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.6689 Highly Informative Inherited
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0.002687 Highly Informative Inherited
Biological Process (BP) humoral immune response 0.07743 Highly Informative Inherited
Biological Process (BP) innate immune response 1 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.00000003028 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0.00002374 Moderately Informative Direct
Molecular Function (MF) anion binding 0.4055 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.05616 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0.000003686 Informative Direct
Molecular Function (MF) protein dimerization activity 0.000005154 Informative Direct
Molecular Function (MF) sulfur compound binding 0.000001792 Informative Direct
Molecular Function (MF) receptor binding 0.0002111 Informative Direct
Molecular Function (MF) enzyme binding 0.01161 Informative Inherited
Molecular Function (MF) protein homodimerization activity 0.000001605 Highly Informative Direct
Molecular Function (MF) calcium ion binding 0.0000000003587 Highly Informative Direct
Molecular Function (MF) heparin binding 0.0000001248 Highly Informative Direct
Molecular Function (MF) cell adhesion molecule binding 0.0004126 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.7603 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) protein complex 0.9898 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane part 0 Moderately Informative Direct
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.9135 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.0801 Moderately Informative Inherited
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) side of membrane 0 Informative Direct
Cellular Component (CC) synapse 0.8809 Informative Inherited
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0 Highly Informative Direct
Cellular Component (CC) nucleolar part 0.0000000003385 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details) Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)urinary system disease0.01584Moderately InformativeInherited
Disease Ontology (DO)obstructive lung disease0.5219Moderately InformativeInherited
Disease Ontology (DO)glomerulonephritis0.00007596InformativeDirect
Disease Ontology (DO)opportunistic mycosis0.0004362InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.512Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the globe0.09894Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.2998Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of urine homeostasis0.003023InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.00392InformativeInherited
Phenotypic Abnormality (PA)Abnormal renal physiology0.006372InformativeInherited
Phenotypic Abnormality (PA)Anterior lenticonus0.000000009986Highly InformativeDirect
Phenotypic Abnormality (PA)Hematuria0.0003418Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0.000002565Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.004042Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.2852Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.3997Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.918Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.00001848Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell physiology0.001694Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.1001Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2502Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.5302Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.6857Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.7294Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.7622Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.9834Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte migration0.02343InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.05238InformativeInherited
Mammalian Phenotype (MP)fibrosis0.07198InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.08207InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.2415InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.3307InformativeInherited
Mammalian Phenotype (MP)skin hemorrhage0.0005102Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating interleukin-17 level0.06127Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.07432Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.1202Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)epithelium0.01879Moderately InformativeInherited
Fly Anatomy (FA)epithelial tube0.0005879InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0.0006452Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0.000123Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0.00003706Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0.00000001307InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)sensory organs0.0000363Least InformativeDirect
Drugbank ATC_code (DB)musculo-skeletal system0.00000001604Moderately InformativeDirect
Drugbank ATC_code (DB)nasal preparations0.0000003037Moderately InformativeDirect
Drugbank ATC_code (DB)other drugs for disorders of the musculo-skeletal system0InformativeDirect
Drugbank ATC_code (DB)cicatrizants0.0000000000001761InformativeDirect
Drugbank ATC_code (DB)surgical aids0.000000000001841InformativeDirect
Drugbank ATC_code (DB)hyaluronic acid0Highly InformativeDirect
Drugbank ATC_code (DB)hyaluronic acid0Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity0.00000009985InformativeDirect
Biological processCytolysis0.0001362InformativeDirect
Biological processAngiogenesis0.0004263InformativeDirect
Biological processAcute phase0.00000000003256Highly InformativeDirect
Biological processAdaptive immunity0.0000001153Highly InformativeDirect
Biological processHemolysis0.00001756Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Coding sequence diversityPolymorphism0.00001796Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane0.0000007647Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainSignal-anchor0InformativeDirect
DomainImmunoglobulin domain0.00000004393InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi0Highly InformativeDirect
DomainLaminin EGF-like domain0.0000000001548Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationToxin0InformativeDirect
Post-translational modificationAntimicrobial0.0000000003487InformativeDirect
Post-translational modificationHemagglutinin0Highly InformativeDirect
Post-translational modificationHemostasis impairing toxin0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPalmitate0.0006419Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.001238Least InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 72 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 72 hidden Markov models representing the C-type lectin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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