SUPERFAMILY 1.75 HMM library and genome assignments server


C-type lectin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Families:   C-type lectin domain [ 56437] (28)
  Aerolysin/Pertussis toxin (APT) domain [ 56467] (2)
  Invasin/intimin cell-adhesion fragment, C-terminal domain [ 56472] (2)
  Link domain [ 56477] (2)
  Endostatin [ 56480] (2)
  Noncollagenous (NC1) domain of collagen IV [ 75585]
  Sulfatase-modifying factor-like [ 143959] (2)
  Mtd variable domain [ 143964]


Superfamily statistics
Genomes (1,619) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 26,536 39,333 125
Proteins 19,011 31,472 121


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.00043651.449e-11Least InformativeDirect
Biological Process (BP)regulation of cellular process0.60071Least InformativeInherited
Biological Process (BP)single-organism cellular process0.19930.2098Least InformativeInherited
Biological Process (BP)multicellular organismal process0.11493.126e-14Least InformativeInherited
Biological Process (BP)multi-organism process1.79e-081.055e-07Moderately InformativeDirect
Biological Process (BP)immune system process1.579e-061.435e-14Moderately InformativeDirect
Biological Process (BP)positive regulation of response to stimulus0.040571.665e-11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.11031Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.052680.2429Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.065381Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.20740.8088Moderately InformativeInherited
Biological Process (BP)signal transduction0.039080.05012Moderately InformativeInherited
Biological Process (BP)biological adhesion6.493e-110InformativeDirect
Biological Process (BP)defense response9.297e-070InformativeDirect
Biological Process (BP)immune response0.00028290.0001815InformativeDirect
Biological Process (BP)regulation of immune response0.00036693.246e-10InformativeDirect
Biological Process (BP)negative regulation of developmental process0.00053930.1291InformativeInherited
Biological Process (BP)regulation of cell proliferation0.0060940.3903InformativeInherited
Biological Process (BP)positive regulation of immune system process0.023886.369e-11InformativeInherited
Biological Process (BP)regulation of defense response0.34130.3141InformativeInherited
Biological Process (BP)cell adhesion3.257e-110Highly InformativeDirect
Biological Process (BP)ossification0.00025242.216e-08Highly InformativeDirect
Biological Process (BP)regulation of wound healing4.954e-060.003222Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation4.54e-080.0183Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.00025260.3667Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.00018430.06921Highly InformativeInherited
Biological Process (BP)positive regulation of defense response0.0025495.109e-06Highly InformativeInherited
Biological Process (BP)regulation of innate immune response0.0081716.035e-06Highly InformativeInherited
Biological Process (BP)immune response-activating signal transduction0.63190.6684Highly InformativeInherited
Molecular Function (MF)binding2.045e-100Least InformativeDirect
Molecular Function (MF)receptor activity1.176e-080InformativeDirect
Molecular Function (MF)monosaccharide binding10.759Highly InformativeInherited
Cellular Component (CC)membrane0.0011130Least InformativeInherited
Cellular Component (CC)extracellular region part7.91e-060Moderately InformativeDirect
Cellular Component (CC)plasma membrane2.702e-050Moderately InformativeDirect
Cellular Component (CC)cell surface9.219e-120InformativeDirect
Cellular Component (CC)extracellular matrix5.728e-060InformativeDirect
Cellular Component (CC)extracellular matrix part4.543e-050Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix0.00010170Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1.449e-11 Least Informative Direct
Biological Process (BP) multicellular organismal process 3.126e-14 Least Informative Direct
Biological Process (BP) developmental process 1.053e-07 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.2098 Least Informative Inherited
Biological Process (BP) localization 0.821 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) multi-organism process 1.055e-07 Moderately Informative Direct
Biological Process (BP) immune system process 1.435e-14 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 1.665e-11 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.8088 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.001757 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.06046 Moderately Informative Inherited
Biological Process (BP) reproduction 0.5645 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.2429 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.8915 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.532 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.1083 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.983 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.05012 Moderately Informative Inherited
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) immune response 0.0001815 Informative Direct
Biological Process (BP) regulation of immune response 3.246e-10 Informative Direct
Biological Process (BP) positive regulation of immune system process 6.369e-11 Informative Direct
Biological Process (BP) positive regulation of transport 2.337e-07 Informative Direct
Biological Process (BP) response to wounding 1.524e-05 Informative Direct
Biological Process (BP) vesicle-mediated transport 5.355e-05 Informative Direct
Biological Process (BP) regulation of cytokine production 1.286e-09 Informative Direct
Biological Process (BP) muscle system process 6.131e-06 Informative Direct
Biological Process (BP) cellular component movement 1.849e-05 Informative Direct
Biological Process (BP) locomotion 3.122e-05 Informative Direct
Biological Process (BP) regulation of immune effector process 0.0003837 Informative Direct
Biological Process (BP) cell projection organization 0.005527 Informative Inherited
Biological Process (BP) response to oxidative stress 0.5643 Informative Inherited
Biological Process (BP) generation of neurons 0.196 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.4823 Informative Inherited
Biological Process (BP) tube development 0.004962 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) reproductive system development 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.4292 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.1553 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.1784 Informative Inherited
Biological Process (BP) regulation of defense response 0.3141 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.3474 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.4103 Informative Inherited
Biological Process (BP) response to bacterium 0.008407 Informative Inherited
Biological Process (BP) response to lipid 0.2658 Informative Inherited
Biological Process (BP) regulation of ion transport 0.1398 Informative Inherited
Biological Process (BP) regulation of secretion 0.001248 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.1291 Informative Inherited
Biological Process (BP) leukocyte activation 0.3044 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.03149 Informative Inherited
Biological Process (BP) gland development 0.2057 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) positive regulation of protein metabolic process 0.1018 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.3903 Informative Inherited
Biological Process (BP) muscle structure development 0.7163 Informative Inherited
Biological Process (BP) muscle tissue development 0.4396 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.91 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) ossification 2.216e-08 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 5.109e-06 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 6.035e-06 Highly Informative Direct
Biological Process (BP) wound healing 0.0008479 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) regulation of protein processing 3.566e-12 Highly Informative Direct
Biological Process (BP) multicellular organismal metabolic process 1.955e-08 Highly Informative Direct
Biological Process (BP) renal system development 6.998e-08 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 9.25e-08 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 8.461e-07 Highly Informative Direct
Biological Process (BP) chemical homeostasis within a tissue 4.248e-06 Highly Informative Direct
Biological Process (BP) chemotaxis 7.985e-05 Highly Informative Direct
Biological Process (BP) regulation of coagulation 0.0001018 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.0001144 Highly Informative Direct
Biological Process (BP) neuron projection development 0.0001199 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.000187 Highly Informative Direct
Biological Process (BP) inflammatory response 0.0002997 Highly Informative Direct
Biological Process (BP) glycosaminoglycan metabolic process 0.0003383 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.0003991 Highly Informative Direct
Biological Process (BP) regulation of hemostasis 0.0004576 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.0004768 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0004859 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 0.0005125 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0.000577 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.0005793 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.0006519 Highly Informative Direct
Biological Process (BP) regulation of endocytosis 0.0009801 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.01089 Highly Informative Inherited
Biological Process (BP) cell part morphogenesis 0.001162 Highly Informative Inherited
Biological Process (BP) regulation of wound healing 0.003222 Highly Informative Inherited
Biological Process (BP) defense response to bacterium 0.1077 Highly Informative Inherited
Biological Process (BP) regulation of cytokine secretion 0.02267 Highly Informative Inherited
Biological Process (BP) positive regulation of lymphocyte mediated immunity 0.05347 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte mediated cytotoxicity 0.6484 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.2827 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.0183 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.3667 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 0.03317 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.06921 Highly Informative Inherited
Biological Process (BP) aging 0.01697 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.1191 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.001499 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.538 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.6684 Highly Informative Inherited
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0.002723 Highly Informative Inherited
Biological Process (BP) humoral immune response 0.0783 Highly Informative Inherited
Biological Process (BP) innate immune response 1 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) structural molecule activity 2.401e-05 Moderately Informative Direct
Molecular Function (MF) anion binding 0.4068 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.05569 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 6.781e-06 Informative Direct
Molecular Function (MF) protein dimerization activity 4.917e-06 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0 Informative Direct
Molecular Function (MF) sulfur compound binding 8.001e-07 Informative Direct
Molecular Function (MF) receptor binding 0.0002088 Informative Direct
Molecular Function (MF) enzyme binding 0.01077 Informative Inherited
Molecular Function (MF) protein homodimerization activity 1.661e-06 Highly Informative Direct
Molecular Function (MF) calcium ion binding 3.543e-10 Highly Informative Direct
Molecular Function (MF) heparin binding 1.238e-07 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.759 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.0799 Moderately Informative Inherited
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) integral to membrane 0.02003 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.8961 Informative Inherited
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 1.128e-05 Highly Informative Direct
Cellular Component (CC) nucleolar part 3.474e-10 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details) Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)urinary system disease0.01584Moderately InformativeInherited
Disease Ontology (DO)obstructive lung disease0.5219Moderately InformativeInherited
Disease Ontology (DO)glomerulonephritis7.596e-05InformativeDirect
Disease Ontology (DO)opportunistic mycosis0.0004362InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.512Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the globe0.09894Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.2998Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of urine homeostasis0.003023InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.00392InformativeInherited
Phenotypic Abnormality (PA)Abnormal renal physiology0.006372InformativeInherited
Phenotypic Abnormality (PA)Anterior lenticonus9.986e-09Highly InformativeDirect
Phenotypic Abnormality (PA)Hematuria0.0003418Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype2.565e-06Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.004042Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.2852Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.3997Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.918Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal protein level1.848e-05Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell physiology0.001694Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.1001Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2502Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.5302Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.6857Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.7294Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.7622Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.9834Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte migration0.02343InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.05238InformativeInherited
Mammalian Phenotype (MP)fibrosis0.07198InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.08207InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.2415InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.3307InformativeInherited
Mammalian Phenotype (MP)skin hemorrhage0.0005102Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating interleukin-17 level0.06127Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.07432Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.1202Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)epithelium0.01879Moderately InformativeInherited
Fly Anatomy (FA)epithelial tube0.0005879InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0.0006452Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0.000123Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases3.706e-05Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase1.307e-08InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity9.985e-08InformativeDirect
Biological processCytolysis0.0001362InformativeDirect
Biological processAngiogenesis0.0004263InformativeDirect
Biological processAcute phase3.256e-11Highly InformativeDirect
Biological processAdaptive immunity1.153e-07Highly InformativeDirect
Biological processHemolysis1.756e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Coding sequence diversityPolymorphism1.796e-05Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane7.647e-07Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainSignal-anchor0InformativeDirect
DomainImmunoglobulin domain4.393e-08InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi0Highly InformativeDirect
DomainLaminin EGF-like domain1.548e-10Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationToxin0InformativeDirect
Post-translational modificationAntimicrobial3.487e-10InformativeDirect
Post-translational modificationHemagglutinin0Highly InformativeDirect
Post-translational modificationHemostasis impairing toxin0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPalmitate0.0006419Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.001238Least InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 72 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 72 hidden Markov models representing the C-type lectin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]