SUPERFAMILY 1.75 HMM library and genome assignments server


C-type lectin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Families:   C-type lectin domain [ 56437] (28)
  Aerolysin/Pertussis toxin (APT) domain [ 56467] (2)
  Invasin/intimin cell-adhesion fragment, C-terminal domain [ 56472] (2)
  Link domain [ 56477] (2)
  Endostatin [ 56480] (2)
  Noncollagenous (NC1) domain of collagen IV [ 75585]
  Sulfatase-modifying factor-like [ 143959] (2)
  Mtd variable domain [ 143964]


Superfamily statistics
Genomes (1,612) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 25,255 39,333 125
Proteins 18,295 31,472 121


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.00089071.664e-10Least InformativeDirect
Biological Process (BP)regulation of cellular process0.62951Least InformativeInherited
Biological Process (BP)single-organism cellular process0.13850.06564Least InformativeInherited
Biological Process (BP)multicellular organismal process0.14761.077e-14Least InformativeInherited
Biological Process (BP)multi-organism process4.162e-096.709e-07Moderately InformativeDirect
Biological Process (BP)immune system process1.018e-063.722e-15Moderately InformativeDirect
Biological Process (BP)positive regulation of response to stimulus0.04122.611e-11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.11321Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.051920.2313Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.064811Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.1950.7528Moderately InformativeInherited
Biological Process (BP)biological adhesion2.968e-110InformativeDirect
Biological Process (BP)defense response5.502e-060InformativeDirect
Biological Process (BP)immune response0.00016440.0001128InformativeDirect
Biological Process (BP)regulation of immune response0.0003699.253e-10InformativeDirect
Biological Process (BP)regulation of response to stress0.004363.896e-08InformativeInherited
Biological Process (BP)negative regulation of developmental process0.00054570.08391InformativeInherited
Biological Process (BP)regulation of cell proliferation0.0065630.3129InformativeInherited
Biological Process (BP)cell adhesion2.243e-110Highly InformativeDirect
Biological Process (BP)ossification0.00016721.291e-08Highly InformativeDirect
Biological Process (BP)regulation of wound healing6.625e-060.003666Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation2.508e-080.01416Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.00025310.2901Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.00019130.05975Highly InformativeInherited
Molecular Function (MF)binding2.212e-110Least InformativeDirect
Molecular Function (MF)receptor activity6.873e-090InformativeDirect
Molecular Function (MF)monosaccharide binding10.7843Highly InformativeInherited
Cellular Component (CC)membrane0.0002890Least InformativeDirect
Cellular Component (CC)plasma membrane3.777e-060Moderately InformativeDirect
Cellular Component (CC)extracellular region part1.544e-050Moderately InformativeDirect
Cellular Component (CC)cell surface6.382e-120InformativeDirect
Cellular Component (CC)extracellular matrix4.792e-060InformativeDirect
Cellular Component (CC)extracellular matrix part3.775e-050Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix7.355e-050Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1.664e-10 Least Informative Direct
Biological Process (BP) multicellular organismal process 1.077e-14 Least Informative Direct
Biological Process (BP) developmental process 3.685e-09 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.06564 Least Informative Inherited
Biological Process (BP) localization 0.553 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) multi-organism process 6.709e-07 Moderately Informative Direct
Biological Process (BP) immune system process 3.722e-15 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 2.611e-11 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 0.0006114 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.7528 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.001449 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.07894 Moderately Informative Inherited
Biological Process (BP) reproduction 0.4224 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.2313 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.7235 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.3975 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.1425 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.02134 Moderately Informative Inherited
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) immune response 0.0001128 Informative Direct
Biological Process (BP) regulation of immune response 9.253e-10 Informative Direct
Biological Process (BP) regulation of response to stress 3.896e-08 Informative Direct
Biological Process (BP) positive regulation of immune system process 2.984e-10 Informative Direct
Biological Process (BP) positive regulation of transport 1.852e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 7.542e-06 Informative Direct
Biological Process (BP) response to wounding 0.000145 Informative Direct
Biological Process (BP) regulation of cytokine production 1.425e-09 Informative Direct
Biological Process (BP) muscle system process 3.274e-06 Informative Direct
Biological Process (BP) locomotion 1.087e-05 Informative Direct
Biological Process (BP) cellular component movement 1.75e-05 Informative Direct
Biological Process (BP) cellular component disassembly 0.0002196 Informative Direct
Biological Process (BP) regulation of immune effector process 0.0003258 Informative Direct
Biological Process (BP) regulation of establishment of protein localization 0.0007304 Informative Direct
Biological Process (BP) regulation of secretion 0.000954 Informative Direct
Biological Process (BP) mitochondrion organization 0.0009665 Informative Direct
Biological Process (BP) cell projection organization 0.004893 Informative Inherited
Biological Process (BP) response to oxidative stress 0.2993 Informative Inherited
Biological Process (BP) generation of neurons 0.1307 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.4763 Informative Inherited
Biological Process (BP) tube development 0.005485 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) reproductive system development 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) response to other organism 0.01589 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.1589 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.1579 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.262 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.3275 Informative Inherited
Biological Process (BP) regulation of ion transport 0.1352 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.08391 Informative Inherited
Biological Process (BP) leukocyte activation 0.2798 Informative Inherited
Biological Process (BP) gland development 0.2111 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.3129 Informative Inherited
Biological Process (BP) muscle structure development 0.6973 Informative Inherited
Biological Process (BP) muscle tissue development 0.398 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.852 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) ossification 1.291e-08 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 1.986e-05 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 1.505e-05 Highly Informative Direct
Biological Process (BP) regulation of cell killing 0 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte mediated immunity 0 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) regulation of protein processing 1.863e-12 Highly Informative Direct
Biological Process (BP) multicellular organismal metabolic process 1.646e-08 Highly Informative Direct
Biological Process (BP) renal system development 6.554e-08 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 7.954e-08 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 5.677e-07 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in neuron differentiation 9.519e-05 Highly Informative Direct
Biological Process (BP) chemotaxis 9.793e-05 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.0001027 Highly Informative Direct
Biological Process (BP) regulation of coagulation 0.0001168 Highly Informative Direct
Biological Process (BP) axon development 0.0001868 Highly Informative Direct
Biological Process (BP) glycosaminoglycan metabolic process 0.0001936 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.0003107 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0003137 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.0003309 Highly Informative Direct
Biological Process (BP) regulation of hemostasis 0.000515 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.0005603 Highly Informative Direct
Biological Process (BP) regulation of endocytosis 0.0006075 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0.0006184 Highly Informative Direct
Biological Process (BP) phagocytosis 0.0008851 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.008646 Highly Informative Inherited
Biological Process (BP) cell projection morphogenesis 0.002816 Highly Informative Inherited
Biological Process (BP) regulation of wound healing 0.003666 Highly Informative Inherited
Biological Process (BP) defense response to bacterium 0.2759 Highly Informative Inherited
Biological Process (BP) regulation of cytokine secretion 0.01764 Highly Informative Inherited
Biological Process (BP) tissue homeostasis 0.05314 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.2854 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.01416 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.2901 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 0.02715 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.05975 Highly Informative Inherited
Biological Process (BP) aging 0.0156 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.09291 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.5472 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte mediated immunity 0.002164 Highly Informative Inherited
Biological Process (BP) inflammatory response 0.005228 Highly Informative Inherited
Biological Process (BP) wound healing 0.008305 Highly Informative Inherited
Biological Process (BP) activation of immune response 0.007019 Highly Informative Inherited
Biological Process (BP) immune response-regulating signaling pathway 0.0033 Highly Informative Inherited
Biological Process (BP) humoral immune response 0.07008 Highly Informative Inherited
Biological Process (BP) innate immune response 0.8163 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) structural molecule activity 1.211e-05 Moderately Informative Direct
Molecular Function (MF) anion binding 0.3025 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.02742 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 2.363e-06 Informative Direct
Molecular Function (MF) protein dimerization activity 1.81e-06 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0 Informative Direct
Molecular Function (MF) sulfur compound binding 7.926e-07 Informative Direct
Molecular Function (MF) receptor binding 9.584e-05 Informative Direct
Molecular Function (MF) enzyme binding 0.004274 Informative Inherited
Molecular Function (MF) protein homodimerization activity 1.746e-06 Highly Informative Direct
Molecular Function (MF) calcium ion binding 1.175e-10 Highly Informative Direct
Molecular Function (MF) heparin binding 1.634e-07 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.7843 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.9966 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.05204 Moderately Informative Inherited
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) integral to membrane 0.01955 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.8897 Informative Inherited
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 7.255e-06 Highly Informative Direct
Cellular Component (CC) nucleolar part 2.089e-10 Highly Informative Direct
Cellular Component (CC) neuromuscular junction 7.48e-05 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details) Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)urinary system disease0.01738Moderately InformativeInherited
Disease Ontology (DO)lung disease0.01785Moderately InformativeInherited
Disease Ontology (DO)opportunistic mycosis0.0003576InformativeDirect
Disease Ontology (DO)nephritis0.03588InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.5203Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the globe0.1026Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.3053Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of urine homeostasis0.003341InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.004316InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.1131InformativeInherited
Phenotypic Abnormality (PA)Anterior lenticonus9.665e-09Highly InformativeDirect
Phenotypic Abnormality (PA)Hematuria0.0003812Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype2.451e-06Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.00374Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.2169Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.3908Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.9152Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)altered susceptibility to infection3.592e-08Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal protein level1.801e-05Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell physiology0.003981Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.1044Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.1088Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2387Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.5129Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.787Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.8223Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.8494Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.9834Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hepatobiliary system physiology0.002937InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte migration0.02866InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.05257InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.08261InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.2519InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.3318InformativeInherited
Mammalian Phenotype (MP)skin hemorrhage0.0005195Highly InformativeDirect
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0006021Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating interleukin-17 level0.05355Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.1169Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.1242Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)portion of tissue0.1157Moderately InformativeInherited
Fly Anatomy (FA)epithelial tube0.0006505InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0.0006473Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0.0001239Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases3.667e-05Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase1.283e-08InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity1.217e-07InformativeDirect
Biological processCytolysis0.0001332InformativeDirect
Biological processAngiogenesis0.0004229InformativeDirect
Biological processAcute phase3.213e-11Highly InformativeDirect
Biological processAdaptive immunity1.273e-07Highly InformativeDirect
Biological processHemolysis1.709e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Coding sequence diversityPolymorphism2.915e-05Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane6.589e-07Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainSignal-anchor0InformativeDirect
DomainImmunoglobulin domain4.209e-08InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi0Highly InformativeDirect
DomainLaminin EGF-like domain1.53e-10Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationToxin0InformativeDirect
Post-translational modificationAntimicrobial3.41e-10InformativeDirect
Post-translational modificationHemagglutinin0Highly InformativeDirect
Post-translational modificationHemostasis impairing toxin0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPalmitate0.0006338Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.001243Least InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 72 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 72 hidden Markov models representing the C-type lectin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]