SUPERFAMILY 1.75 HMM library and genome assignments server


C-type lectin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Families:   C-type lectin domain [ 56437] (28)
  Aerolysin/Pertussis toxin (APT) domain [ 56467] (2)
  Invasin/intimin cell-adhesion fragment, C-terminal domain [ 56472] (2)
  Link domain [ 56477] (2)
  Endostatin [ 56480] (2)
  Noncollagenous (NC1) domain of collagen IV [ 75585]
  Sulfatase-modifying factor-like [ 143959] (2)
  Mtd variable domain [ 143964]


Superfamily statistics
Genomes (1,574) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 24,448 28,663 125
Proteins 17,685 22,343 121


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of cellular process0.66861Least InformativeInherited
Biological Process (BP)single-organism cellular process0.18950.0355Least InformativeInherited
Biological Process (BP)response to stimulus0.0037591.224e-09Least InformativeInherited
Biological Process (BP)multicellular organismal process0.26775.076e-14Least InformativeInherited
Biological Process (BP)multi-organism process6.911e-082.702e-06Moderately InformativeDirect
Biological Process (BP)immune system process9.15e-068.23e-12Moderately InformativeDirect
Biological Process (BP)positive regulation of response to stimulus0.0812.474e-11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.087511Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.092420.5598Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.042581Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.13820.9557Moderately InformativeInherited
Biological Process (BP)biological adhesion2.999e-100InformativeDirect
Biological Process (BP)defense response1.176e-050InformativeDirect
Biological Process (BP)negative regulation of developmental process0.00039630.07414InformativeInherited
Biological Process (BP)positive regulation of cell proliferation0.00024080.6584InformativeInherited
Biological Process (BP)cell adhesion1.701e-100Highly InformativeDirect
Biological Process (BP)ossification9.572e-051.416e-07Highly InformativeDirect
Biological Process (BP)regulation of wound healing5.32e-070.0117Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation1.483e-080.01416Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.00023220.2843Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.00026030.0624Highly InformativeInherited
Molecular Function (MF)binding4.384e-090Least InformativeDirect
Molecular Function (MF)receptor activity3e-080InformativeDirect
Molecular Function (MF)monosaccharide binding10.7153Highly InformativeInherited
Cellular Component (CC)membrane0.00055750Least InformativeDirect
Cellular Component (CC)extracellular region part0.00013710Moderately InformativeDirect
Cellular Component (CC)plasma membrane part0.00020550Moderately InformativeDirect
Cellular Component (CC)cell surface5.042e-110InformativeDirect
Cellular Component (CC)extracellular matrix3.67e-060InformativeDirect
Cellular Component (CC)extracellular matrix part2.99e-050Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix3.247e-050Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1.224e-09 Least Informative Direct
Biological Process (BP) multicellular organismal process 5.076e-14 Least Informative Direct
Biological Process (BP) developmental process 2.809e-08 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.0355 Least Informative Inherited
Biological Process (BP) localization 0.6972 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) multi-organism process 2.702e-06 Moderately Informative Direct
Biological Process (BP) immune system process 8.23e-12 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 2.474e-11 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.9557 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.001965 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.2003 Moderately Informative Inherited
Biological Process (BP) reproduction 0.4164 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.9165 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.3819 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.957 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 0.002369 Moderately Informative Inherited
Biological Process (BP) organ development 0.06997 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.5598 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.00143 Moderately Informative Inherited
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) regulation of immune response 3.979e-09 Informative Direct
Biological Process (BP) positive regulation of immune system process 5.452e-10 Informative Direct
Biological Process (BP) response to wounding 0.0001136 Informative Direct
Biological Process (BP) regulation of cytokine production 5.658e-10 Informative Direct
Biological Process (BP) positive regulation of transport 1.279e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 1.584e-05 Informative Direct
Biological Process (BP) locomotion 6.355e-05 Informative Direct
Biological Process (BP) cellular component movement 0.0001535 Informative Direct
Biological Process (BP) regulation of immune effector process 0.0003278 Informative Direct
Biological Process (BP) regulation of secretion 0.0005838 Informative Direct
Biological Process (BP) cell activation 0.0009904 Informative Direct
Biological Process (BP) cell projection organization 0.02437 Informative Inherited
Biological Process (BP) response to oxidative stress 0.1614 Informative Inherited
Biological Process (BP) regulation of protein localization 0.3629 Informative Inherited
Biological Process (BP) generation of neurons 0.2713 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.6308 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) reproductive structure development 0.7491 Informative Inherited
Biological Process (BP) response to bacterium 0.06227 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.1618 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.1913 Informative Inherited
Biological Process (BP) regulation of defense response 0.3819 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.2603 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.3235 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) regulation of ion transport 0.09993 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.07414 Informative Inherited
Biological Process (BP) gland development 0.2069 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) positive regulation of protein metabolic process 0.05882 Informative Inherited
Biological Process (BP) positive regulation of cell proliferation 0.6584 Informative Inherited
Biological Process (BP) muscle structure development 0.6319 Informative Inherited
Biological Process (BP) muscle tissue development 0.2677 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.8474 Informative Inherited
Biological Process (BP) immune response 0.006144 Informative Inherited
Biological Process (BP) immune effector process 0.9713 Informative Inherited
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) ossification 1.416e-07 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 4.023e-05 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 6.057e-05 Highly Informative Direct
Biological Process (BP) regulation of cell killing 0 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte mediated immunity 0 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) regulation of protein processing 1.02e-12 Highly Informative Direct
Biological Process (BP) multicellular organismal catabolic process 3.335e-10 Highly Informative Direct
Biological Process (BP) collagen metabolic process 1.448e-09 Highly Informative Direct
Biological Process (BP) renal system development 4.491e-08 Highly Informative Direct
Biological Process (BP) positive regulation of secretion 1.384e-07 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 6.135e-07 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 8.395e-05 Highly Informative Direct
Biological Process (BP) neuron projection development 9.648e-05 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.0001905 Highly Informative Direct
Biological Process (BP) glycosaminoglycan metabolic process 0.0002094 Highly Informative Direct
Biological Process (BP) chemotaxis 0.0002465 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0002679 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.0003206 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.0003474 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.0005378 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.0006907 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0.0007278 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 0.0009245 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.01015 Highly Informative Inherited
Biological Process (BP) regulation of wound healing 0.0117 Highly Informative Inherited
Biological Process (BP) defense response to bacterium 0.1448 Highly Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.04897 Highly Informative Inherited
Biological Process (BP) regulation of protein secretion 0.003188 Highly Informative Inherited
Biological Process (BP) positive regulation of protein transport 0.33 Highly Informative Inherited
Biological Process (BP) tissue homeostasis 0.1318 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.2659 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.01416 Highly Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.403 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.2843 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 0.02784 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.0624 Highly Informative Inherited
Biological Process (BP) aging 0.01553 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.09196 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.002705 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.4997 Highly Informative Inherited
Biological Process (BP) positive regulation of leukocyte mediated immunity 0.001265 Highly Informative Inherited
Biological Process (BP) inflammatory response 0.001548 Highly Informative Inherited
Biological Process (BP) wound healing 0.01609 Highly Informative Inherited
Biological Process (BP) activation of immune response 0.00646 Highly Informative Inherited
Biological Process (BP) immune response-regulating signaling pathway 0.01438 Highly Informative Inherited
Biological Process (BP) humoral immune response 0.01753 Highly Informative Inherited
Biological Process (BP) innate immune response 1 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) structural molecule activity 7.363e-06 Moderately Informative Direct
Molecular Function (MF) anion binding 0.2755 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.02322 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) protein dimerization activity 4.014e-06 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0 Informative Direct
Molecular Function (MF) molecular transducer activity 1.527e-09 Informative Direct
Molecular Function (MF) sulfur compound binding 3.842e-07 Informative Direct
Molecular Function (MF) receptor binding 9.427e-05 Informative Direct
Molecular Function (MF) enzyme binding 0.006631 Informative Inherited
Molecular Function (MF) protein homodimerization activity 3.224e-06 Highly Informative Direct
Molecular Function (MF) calcium ion binding 1.026e-10 Highly Informative Direct
Molecular Function (MF) heparin binding 1.663e-07 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.7153 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane part 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.04512 Moderately Informative Inherited
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) integral to membrane 0.02026 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 1 Informative Inherited
Cellular Component (CC) nucleolus 0.05885 Informative Inherited
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0 Highly Informative Direct
Cellular Component (CC) integral to plasma membrane 7.4e-06 Highly Informative Direct
Cellular Component (CC) nucleolar part 2.19e-10 Highly Informative Direct
Cellular Component (CC) neuromuscular junction 7.03e-05 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details) Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)kidney disease0.0066Moderately InformativeInherited
Disease Ontology (DO)lung disease0.01795Moderately InformativeInherited
Disease Ontology (DO)opportunistic mycosis0.000358InformativeDirect
Disease Ontology (DO)nephritis0.0344InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.521Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the globe0.1011Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.3057Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of urine homeostasis0.003309InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.004275InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.1131InformativeInherited
Phenotypic Abnormality (PA)Anterior lenticonus9.342e-09Highly InformativeDirect
Phenotypic Abnormality (PA)Hematuria0.000374Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype2.375e-06Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.003635Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.271Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.3784Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.914Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal protein level1.378e-05Moderately InformativeDirect
Mammalian Phenotype (MP)renal/urinary system phenotype0.1568Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.1952Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic system physiology0.3004Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.4981Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.7935Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.8291Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.8544Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.9836Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte migration0.03007InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.07882InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.1071InformativeInherited
Mammalian Phenotype (MP)other phenotype0.2412InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.2504InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.3375InformativeInherited
Mammalian Phenotype (MP)skin hemorrhage0.0005367Highly InformativeDirect
Mammalian Phenotype (MP)other aberrant phenotype0.04762Highly InformativeInherited
Mammalian Phenotype (MP)abnormal circulating interleukin-17 level0.05716Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.116Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.1232Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0.0006385Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0.0001304Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases3.707e-05Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase1.36e-08InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity1.143e-06InformativeDirect
Biological processCytolysis0.0001123InformativeDirect
Biological processAngiogenesis0.0004015InformativeDirect
Biological processAcute phase3.008e-11Highly InformativeDirect
Biological processHemolysis1.543e-05Highly InformativeDirect
Biological processAdaptive immunity2.611e-05Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Coding sequence diversityPolymorphism3.824e-05Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane5.592e-07Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainSignal-anchor0InformativeDirect
DomainImmunoglobulin domain4.514e-08InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi0Highly InformativeDirect
DomainLaminin EGF-like domain1.572e-10Highly InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationToxin0InformativeDirect
Post-translational modificationAntimicrobial2.335e-10InformativeDirect
Post-translational modificationHemagglutinin0Highly InformativeDirect
Post-translational modificationHemostasis impairing toxin0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPalmitate0.0005922Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.001241Least InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 72 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 72 hidden Markov models representing the C-type lectin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]