SUPERFAMILY 1.75 HMM library and genome assignments server

Bet v1-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TBP-like [ 55944] (11)
Superfamily:   Bet v1-like [ 55961] (10)
Families:   Pathogenesis-related protein 10 (PR10)-like [ 55962] (4)
  STAR domain [ 55966] (4)
  Phoshatidylinositol transfer protein, PITP [ 64388]
  Ring hydroxylating alpha subunit catalytic domain [ 55969] (6)
  AHSA1 domain [ 111168] (11)
  oligoketide cyclase/dehydrase-like [ 118101] (3)
  PA1206-like [ 143839]
  Atu1531-like [ 160742] (2)
  Smu440-like [ 160747]
  CoxG-like [ 160750] (2)


Superfamily statistics
Genomes (2,464) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 28,315 85,069 51
Proteins 26,834 83,696 51


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)response to stimulus0.91491Least InformativeInherited
Biological Process (BP)regulation of cellular process0.28461Least InformativeInherited
Biological Process (BP)localization0.041770.02697Least InformativeInherited
Biological Process (BP)ion transport0.0000050520.000009733Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.00003350.0000000006391Moderately InformativeDirect
Biological Process (BP)response to oxygen-containing compound0.0000055890.0003192Moderately InformativeDirect
Biological Process (BP)cellular response to chemical stimulus0.0020660.2169Moderately InformativeInherited
Biological Process (BP)response to organic substance0.00011910.05554Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.68120.1131Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.90581Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.94551Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus0.1260.3346Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.20880.1716Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.00000054080.001291Moderately InformativeInherited
Biological Process (BP)signal transduction0.0069890.1194Moderately InformativeInherited
Biological Process (BP)organic substance transport0.0068270.000000017Moderately InformativeInherited
Biological Process (BP)anion transport0.00060010.00000000005938InformativeDirect
Biological Process (BP)response to hormone stimulus0.0000018650.00000109InformativeDirect
Biological Process (BP)lipid localization00InformativeDirect
Biological Process (BP)response to lipid0.000015050.0001744InformativeDirect
Biological Process (BP)cellular response to oxygen-containing compound0.0000085810.0001415InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.013190.03471InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.0024710.1323InformativeInherited
Biological Process (BP)organic acid transport0.052890.00001387InformativeInherited
Biological Process (BP)hormone-mediated signaling pathway00.0000000005567Highly InformativeDirect
Biological Process (BP)monocarboxylic acid transport0.0000042220.000002932Highly InformativeDirect
Biological Process (BP)organophosphate ester transport0.0000000000099530.000000000000003755Highly InformativeDirect
Biological Process (BP)response to alcohol0.0000000022750.0000001439Highly InformativeDirect
Molecular Function (MF)binding0.53550.8626Least InformativeInherited
Molecular Function (MF)anion binding0.00014830.01767Moderately InformativeInherited
Molecular Function (MF)transporter activity0.011890.0002373Moderately InformativeInherited
Molecular Function (MF)lipid binding00InformativeDirect
Molecular Function (MF)anion transmembrane transporter activity0.000074950.0003749InformativeDirect
Molecular Function (MF)carboxylic acid binding0.0000000028690.00000001933InformativeDirect
Molecular Function (MF)protein dimerization activity0.00000022950.004381InformativeInherited
Molecular Function (MF)lipid transporter activity0.000000000000037140Highly InformativeDirect
Molecular Function (MF)organic cation transmembrane transporter activity0.00000000088390.00000000003029Highly InformativeDirect
Molecular Function (MF)isoprenoid binding0.000052460.00000005122Highly InformativeDirect
Molecular Function (MF)monocarboxylic acid binding00Highly InformativeDirect
Molecular Function (MF)hormone binding00Highly InformativeDirect
Molecular Function (MF)protein homodimerization activity0.000000031470.0001108Highly InformativeDirect
Molecular Function (MF)alcohol binding00Highly InformativeDirect
Molecular Function (MF)organic hydroxy compound transmembrane transporter activity0.00000000042920.0000000000533Highly InformativeDirect
Cellular Component (CC)cell projection0.17110.1464Moderately InformativeInherited
Cellular Component (CC)cell junction0.0087010.003393InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.02484 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) localization 0.02697 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) lipid metabolic process 0.000003749 Moderately Informative Direct
Biological Process (BP) ion transport 0.000009733 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0.0000000006391 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.000000017 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.0003192 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.2169 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.05554 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.2613 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.5218 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.5161 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.2039 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.5044 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.9069 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 0.07909 Moderately Informative Inherited
Biological Process (BP) reproduction 0.5666 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 0.3346 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 0.1716 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.001291 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.7694 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.1131 Moderately Informative Inherited
Biological Process (BP) tissue development 0.1395 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.1194 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.7783 Moderately Informative Inherited
Biological Process (BP) anion transport 0.00000000005938 Informative Direct
Biological Process (BP) cytoskeleton organization 0.0001068 Informative Direct
Biological Process (BP) response to hormone stimulus 0.00000109 Informative Direct
Biological Process (BP) lipid localization 0 Informative Direct
Biological Process (BP) organic acid transport 0.00001387 Informative Direct
Biological Process (BP) actin filament-based process 0.000007797 Informative Direct
Biological Process (BP) response to lipid 0.0001744 Informative Direct
Biological Process (BP) epithelium development 0.0002531 Informative Direct
Biological Process (BP) reproductive system development 0.0001734 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0001415 Informative Direct
Biological Process (BP) tube development 0.02658 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.7461 Informative Inherited
Biological Process (BP) biological adhesion 0.003171 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.04593 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.004771 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 0.001741 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.03701 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.2268 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.03471 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.1323 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.3582 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.0885 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.1038 Informative Inherited
Biological Process (BP) central nervous system development 0.3407 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.05091 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.1034 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.2871 Informative Inherited
Biological Process (BP) regulation of growth 0.5087 Informative Inherited
Biological Process (BP) organ morphogenesis 0.004816 Informative Inherited
Biological Process (BP) intracellular signal transduction 0.7608 Informative Inherited
Biological Process (BP) membrane lipid metabolic process 0.01131 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.1178 Informative Inherited
Biological Process (BP) steroid biosynthetic process 0.0000002766 Highly Informative Direct
Biological Process (BP) small GTPase mediated signal transduction 0.0006212 Highly Informative Direct
Biological Process (BP) hormone-mediated signaling pathway 0.0000000005567 Highly Informative Direct
Biological Process (BP) post-embryonic development 0.0001225 Highly Informative Direct
Biological Process (BP) epidermal cell differentiation 0.0000002121 Highly Informative Direct
Biological Process (BP) monocarboxylic acid transport 0.000002932 Highly Informative Direct
Biological Process (BP) organophosphate ester transport 0.000000000000003755 Highly Informative Direct
Biological Process (BP) morphogenesis of embryonic epithelium 0.00001379 Highly Informative Direct
Biological Process (BP) neural tube development 0.0003235 Highly Informative Direct
Biological Process (BP) cell junction organization 0.0009071 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 0.00003534 Highly Informative Direct
Biological Process (BP) hormone biosynthetic process 0.000006252 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0.0001338 Highly Informative Direct
Biological Process (BP) response to alcohol 0.0000001439 Highly Informative Direct
Biological Process (BP) cell adhesion 0.00179 Highly Informative Inherited
Biological Process (BP) regulation of protein complex assembly 0.004101 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.0126 Highly Informative Inherited
Biological Process (BP) regulation of actin cytoskeleton organization 0.1333 Highly Informative Inherited
Biological Process (BP) actin filament organization 0.14 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.07603 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.07626 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.6736 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.004137 Highly Informative Inherited
Molecular Function (MF) binding 0.8626 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transporter activity 0.0002373 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.8676 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.01767 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.09148 Moderately Informative Inherited
Molecular Function (MF) enzyme activator activity 0.0006983 Informative Direct
Molecular Function (MF) lipid binding 0 Informative Direct
Molecular Function (MF) anion transmembrane transporter activity 0.0003749 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.00000001933 Informative Direct
Molecular Function (MF) protein dimerization activity 0.004381 Informative Inherited
Molecular Function (MF) GTPase regulator activity 1 Informative Inherited
Molecular Function (MF) lipid transporter activity 0 Highly Informative Direct
Molecular Function (MF) organic cation transmembrane transporter activity 0.00000000003029 Highly Informative Direct
Molecular Function (MF) thiolester hydrolase activity 0.0002474 Highly Informative Direct
Molecular Function (MF) isoprenoid binding 0.00000005122 Highly Informative Direct
Molecular Function (MF) monocarboxylic acid binding 0 Highly Informative Direct
Molecular Function (MF) hormone binding 0 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 0.0001108 Highly Informative Direct
Molecular Function (MF) alcohol binding 0 Highly Informative Direct
Molecular Function (MF) metal cluster binding 0.0000003074 Highly Informative Direct
Molecular Function (MF) organic hydroxy compound transmembrane transporter activity 0.0000000000533 Highly Informative Direct
Molecular Function (MF) small GTPase regulator activity 0.009604 Highly Informative Inherited
Molecular Function (MF) GTPase activator activity 0.01538 Highly Informative Inherited
Cellular Component (CC) cell projection 0.1464 Moderately Informative Inherited
Cellular Component (CC) cell junction 0.003393 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)With a reduced iron-sulfur protein as one donor, a0.0006859Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant1Least InformativeInherited
Worm Phenotype (WP)sensillum morphology variant0.0006942InformativeDirect
Worm Phenotype (WP)growth rate variant0.0001758Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.3085Least InformativeInherited
Plant ANatomical entity (PAN)sporangium0.3384Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.35Least InformativeInherited
Plant ANatomical entity (PAN)root system0.4185Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.5599Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.7997Least InformativeInherited
Plant ANatomical entity (PAN)seed1Least InformativeInherited
Plant ANatomical entity (PAN)root tip0.00002335InformativeDirect
Plant ANatomical entity (PAN)primordium0.0001506InformativeDirect
Plant ANatomical entity (PAN)shoot apical meristem0.000000003173Highly InformativeDirect
Plant ANatomical entity (PAN)reproductive shoot apex0.000000475Highly InformativeDirect
Plant ANatomical entity (PAN)plant ovule0.00000785Highly InformativeDirect
Plant ANatomical entity (PAN)primary root0.00001991Highly InformativeDirect
Plant ANatomical entity (PAN)trichome0.0001855Highly InformativeDirect
Plant ANatomical entity (PAN)vegetative shoot apex0.0005812Highly InformativeDirect
Plant ANatomical entity (PAN)phyllome primordium0.0006747Highly InformativeDirect
Plant structure DEvelopment stage (PDE)seedling development stage0.0001858InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor0Highly InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen0.7776Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.00000008733Least InformativeDirect
Biological processTranscription regulation0.0000000003153Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0InformativeDirect
Biological processLipid transport0InformativeDirect
Biological processPlant defense0InformativeDirect
Biological processAntibiotic biosynthesis0.0000003322Highly InformativeDirect
Cellular componentNucleus0.000000000001352Least InformativeDirect
Cellular componentGolgi apparatus0.00000000003348Moderately InformativeDirect
Cellular componentMitochondrion0.000000000103Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0.0000007035Moderately InformativeDirect
Cellular componentCell junction0.0004708Moderately InformativeDirect
Cellular componentPlastid0.05279Moderately InformativeInherited
Cellular componentVacuole0.0003183InformativeDirect
Cellular componentLipid droplet0.000000001774Highly InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
DomainTransit peptide0Moderately InformativeDirect
Molecular functionDNA-binding0.0000007841Least InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionIron0.00000000000008066Moderately InformativeDirect
Molecular functionNAD0.00000000009069Moderately InformativeDirect
Molecular function2Fe-2S0InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationOxidoreductase0.0000001465Moderately InformativeDirect
Post-translational modificationReceptor0.0002896Moderately InformativeDirect
Post-translational modificationGTPase activation0.000000000573InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationAcetylation0.0005008Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)lipid metabolism0.00004993Least InformativeDirect
UniPathway (UP)aromatic compound metabolism0.0005705Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound degradation0Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0.00004145Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0.0001125Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.0009391Moderately InformativeDirect
UniPathway (UP)terpene metabolism0InformativeDirect
UniPathway (UP)polyketide biosynthesis0.0000000007098InformativeDirect
UniPathway (UP)choline metabolism0.00000001092InformativeDirect
UniPathway (UP)antibiotic biosynthesis0.000002866InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.00003984InformativeDirect
UniPathway (UP)phenylpropanoid degradation0.016InformativeInherited
UniPathway (UP)cholesterol metabolism0.000000000008416Highly InformativeDirect
UniPathway (UP)betaine biosynthesis0.000000009269Highly InformativeDirect
UniPathway (UP)pyruvate metabolism0.00003319Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 42 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bet v1-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 42 hidden Markov models representing the Bet v1-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]