SUPERFAMILY 1.75 HMM library and genome assignments server


Phosphoglucomutase, C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TBP-like [ 55944] (11)
Superfamily:   Phosphoglucomutase, C-terminal domain [ 55957]
Families:   Phosphoglucomutase, C-terminal domain [ 55958] (4)


Superfamily statistics
Genomes (3,172) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 8,892 45,198 9
Proteins 8,886 45,190 9


Functional annotation
General category Metabolism
Detailed category Carbohydrate metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.001008 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.05581 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.7211 Least Informative Inherited
Biological Process (BP) developmental process 0.8911 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.714 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.04718 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.1499 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 2.53e-09 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 6.661e-08 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.0002379 Moderately Informative Direct
Biological Process (BP) immune system process 0.06322 Moderately Informative Inherited
Biological Process (BP) organ development 0.4851 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.00138 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.006655 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.007431 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.008164 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.06425 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.007504 Moderately Informative Inherited
Biological Process (BP) reproduction 0.1563 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.5396 Moderately Informative Inherited
Biological Process (BP) hexose metabolic process 0 Informative Direct
Biological Process (BP) polysaccharide metabolic process 2.135e-06 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 3.565e-05 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0.0001049 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0001972 Informative Direct
Biological Process (BP) hematopoietic or lymphoid organ development 0.0002447 Informative Direct
Biological Process (BP) sexual reproduction 0.003685 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.004437 Informative Inherited
Biological Process (BP) single organism reproductive process 0.006527 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.01407 Informative Inherited
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 4.112e-14 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 2.349e-09 Highly Informative Direct
Biological Process (BP) energy reserve metabolic process 5.665e-08 Highly Informative Direct
Biological Process (BP) aminoglycan biosynthetic process 2.519e-06 Highly Informative Direct
Biological Process (BP) spermatogenesis 2.172e-05 Highly Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) intramolecular transferase activity 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases (phosphomutases)0InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0Moderately InformativeDirect
Plant ANatomical entity (PAN)cotyledon0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular transferases (mutases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases (phosphomutases)0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processGlucose metabolism0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis7.474e-09Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.0045Least InformativeInherited
UniPathway (UP)carbohydrate metabolism0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism1.61e-05Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0.002725Moderately InformativeInherited
UniPathway (UP)lipid biosynthesis0.01933Moderately InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis1.124e-05InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis1InformativeInherited
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis3.341e-10Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 4 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Phosphoglucomutase, C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 4 hidden Markov models representing the Phosphoglucomutase, C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]