SUPERFAMILY 1.73 HMM library and genome assignments server


Creatinase/aminopeptidase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (334)
  Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold:   Creatinase/aminopeptidase [ 55919]
  duplication: composed of two very similar alpha+beta folds
Superfamily:   Creatinase/aminopeptidase [ 55920]
Families:   Creatinase/aminopeptidase [ 55921] (3)


Superfamily statistics
Genomes (1,231) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 6,151 5,954 27
Proteins 6,148 5,951 27


Functional annotation
General category Processes_IC
Detailed category Proteases

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR000994 SSF55920 Protein matches
Abstract

This entry represents the cataltytic core of a group of metallopeptidases and non-peptidase homologs belong to MEROPS peptidase family M24 (clan MG). They includes the enzymes, proline dipeptidase and methionine aminopeptidase.


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Creatinase/aminopeptidase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the Creatinase/aminopeptidase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]