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ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [ 55873]
Superfamily:   ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [ 55874] (4)
Families:   Heat shock protein 90, HSP90, N-terminal domain [ 55875]
  DNA gyrase/MutL, N-terminal domain [ 55879] (6)
  Histidine kinase [ 55884] (7)
  alpha-ketoacid dehydrogenase kinase, C-terminal domain [ 69804] (2)


Superfamily statistics
Genomes (3,242) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 98,222 513,894 56
Proteins 97,141 511,116 56


Functional annotation
General category Processes_IC
Detailed category Protein modification

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.0000018940.0000004544Least InformativeDirect
Biological Process (BP)single-organism cellular process0.00027630.00000002708Least InformativeDirect
Biological Process (BP)response to stimulus0.0000041610Least InformativeDirect
Biological Process (BP)cellular aromatic compound metabolic process0.000066951Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.00019351Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.000062881Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.00015730.24Least InformativeInherited
Biological Process (BP)cellular response to stress0.00007380.00000681Moderately InformativeDirect
Biological Process (BP)DNA metabolic process0.0000000030540.0000000001035InformativeDirect
Biological Process (BP)response to DNA damage stimulus0.000000000000024560.07658InformativeInherited
Molecular Function (MF)binding0.0000017210.00000001363Least InformativeDirect
Molecular Function (MF)nucleic acid binding0.00000026751Moderately InformativeInherited
Molecular Function (MF)DNA binding0.0000000023360.001154InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0.0000004134 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0000004544 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000002708 Least Informative Direct
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.24 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.007962 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) reproduction 0.0003734 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.00000681 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0000000002181 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.00003916 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.0001429 Moderately Informative Direct
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.3943 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.7437 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.9884 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.8481 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.4693 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.007147 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.02653 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1268 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.02056 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.2871 Moderately Informative Inherited
Biological Process (BP) immune system process 0.9408 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) DNA metabolic process 0.0000000001035 Informative Direct
Biological Process (BP) nucleoside monophosphate metabolic process 0 Informative Direct
Biological Process (BP) nucleoside triphosphate metabolic process 0.000000000002751 Informative Direct
Biological Process (BP) purine ribonucleotide metabolic process 0 Informative Direct
Biological Process (BP) phosphorylation 0 Informative Direct
Biological Process (BP) regulation of lipid metabolic process 0.0000787 Informative Direct
Biological Process (BP) response to nutrient levels 0.00002134 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0.00000000000004938 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0 Informative Direct
Biological Process (BP) organophosphate catabolic process 0 Informative Direct
Biological Process (BP) chromosome organization 0.00008742 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0008034 Informative Direct
Biological Process (BP) apoptotic process 0.5667 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.1301 Informative Inherited
Biological Process (BP) reproductive system development 0.003657 Informative Inherited
Biological Process (BP) response to light stimulus 0.006707 Informative Inherited
Biological Process (BP) response to lipid 0.03168 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.7487 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.7391 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.9988 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.00179 Informative Inherited
Biological Process (BP) cell cycle process 0.01562 Informative Inherited
Biological Process (BP) organelle localization 0.1477 Informative Inherited
Biological Process (BP) cytoskeleton organization 0.9907 Informative Inherited
Biological Process (BP) microtubule-based process 1 Informative Inherited
Biological Process (BP) organelle assembly 0.1927 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.3804 Informative Inherited
Biological Process (BP) response to organonitrogen compound 1 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.1093 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.8705 Informative Inherited
Biological Process (BP) proteolysis 1 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.002798 Informative Inherited
Biological Process (BP) regulation of ion transport 0.06755 Informative Inherited
Biological Process (BP) response to hormone stimulus 0.09734 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.03465 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 0.3555 Informative Inherited
Biological Process (BP) cation homeostasis 0.1793 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.07658 Informative Inherited
Biological Process (BP) protein phosphorylation 0.00000000002132 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.000002215 Highly Informative Direct
Biological Process (BP) meiosis 0.00000000000002458 Highly Informative Direct
Biological Process (BP) nucleoside monophosphate catabolic process 0 Highly Informative Direct
Biological Process (BP) purine nucleoside triphosphate catabolic process 0 Highly Informative Direct
Biological Process (BP) purine ribonucleotide catabolic process 0.00002059 Highly Informative Direct
Biological Process (BP) purine ribonucleoside monophosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) ribonucleoside triphosphate catabolic process 0 Highly Informative Direct
Biological Process (BP) purine ribonucleoside triphosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) response to cytokinin stimulus 0.0005826 Highly Informative Direct
Biological Process (BP) regulation of proton transport 0.000006716 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.00000003262 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.00000003706 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 0.00004022 Highly Informative Direct
Biological Process (BP) regulation of nitric oxide biosynthetic process 0.0000000000007451 Highly Informative Direct
Biological Process (BP) purine ribonucleoside catabolic process 0 Highly Informative Direct
Biological Process (BP) intrinsic apoptotic signaling pathway 0.00006076 Highly Informative Direct
Biological Process (BP) response to hypoxia 0.2006 Highly Informative Inherited
Biological Process (BP) cellular response to radiation 0.02883 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.04812 Highly Informative Inherited
Biological Process (BP) spindle organization 0.005754 Highly Informative Inherited
Biological Process (BP) DNA recombination 0.524 Highly Informative Inherited
Biological Process (BP) ubiquitin-dependent protein catabolic process 0.06407 Highly Informative Inherited
Biological Process (BP) proteasomal protein catabolic process 0.008009 Highly Informative Inherited
Biological Process (BP) hormone-mediated signaling pathway 0.5276 Highly Informative Inherited
Biological Process (BP) response to peptide hormone stimulus 0.2628 Highly Informative Inherited
Biological Process (BP) cellular response to peptide 0.2786 Highly Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.06233 Highly Informative Inherited
Biological Process (BP) response to topologically incorrect protein 0.05745 Highly Informative Inherited
Biological Process (BP) monovalent inorganic cation homeostasis 0.002885 Highly Informative Inherited
Biological Process (BP) regulation of DNA metabolic process 0.001076 Highly Informative Inherited
Molecular Function (MF) binding 0.00000001363 Least Informative Direct
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) isomerase activity 0.00000000004645 Moderately Informative Direct
Molecular Function (MF) anion binding 0.006826 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.2477 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) cation binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleotide binding 0.000000000001572 Informative Direct
Molecular Function (MF) magnesium ion binding 0.000007989 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.0000008403 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) enzyme binding 0.7856 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 0.007946 Informative Inherited
Molecular Function (MF) DNA binding 0.001154 Informative Inherited
Molecular Function (MF) protein kinase activity 0.000000000006149 Highly Informative Direct
Molecular Function (MF) ATP binding 0 Highly Informative Direct
Molecular Function (MF) kinase binding 0.0003699 Highly Informative Direct
Molecular Function (MF) structure-specific DNA binding 0.01388 Highly Informative Inherited
Molecular Function (MF) protein domain specific binding 0.008755 Highly Informative Inherited
Cellular Component (CC) intracellular organelle part 0.3549 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.6406 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.05823 Least Informative Inherited
Cellular Component (CC) protein complex 0.9611 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.8114 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.000043 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.00558 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.005641 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.000009679 Informative Direct
Cellular Component (CC) mitochondrial matrix 0.000003435 Informative Direct
Cellular Component (CC) nuclear chromosome part 0.01744 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0.00001265Moderately InformativeDirect
Enzyme Commission (EC)Protein-histidine kinases0InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for isomerases that do not belon1InformativeInherited

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the abdomen0.3834Least InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.045Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal genital system morphology0.08052Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.0824Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by histology0.0007621InformativeDirect
Phenotypic Abnormality (PA)Abnormality of female internal genitalia0.009391InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the intestine0.02InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by anatomical site0.03629InformativeInherited
Phenotypic Abnormality (PA)Uterine neoplasm0.000004576Highly InformativeDirect
Phenotypic Abnormality (PA)Neoplasm of the large intestine0.00001056Highly InformativeDirect
Phenotypic Abnormality (PA)Urinary tract neoplasm0.00009088Highly InformativeDirect
Phenotypic Abnormality (PA)Sarcoma0.0001048Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal reproductive system morphology0.1709Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal gametes0.003754InformativeInherited
Mammalian Phenotype (MP)decreased germ cell number0.003754InformativeInherited
Mammalian Phenotype (MP)abnormal male germ cell morphology0.006266InformativeInherited
Mammalian Phenotype (MP)abnormal spermatogenesis0.009543InformativeInherited
Mammalian Phenotype (MP)azoospermia0.00007504Highly InformativeDirect
Mammalian Phenotype (MP)abnormal meiosis0.00009752Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)gametogenesis variant0.001002Moderately InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)developmental rate defective0.0002562Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0.00001876Moderately InformativeDirect
Enzyme Commission (EC)Protein-histidine kinases0Highly InformativeDirect
Enzyme Commission (EC)DNA topoisomerase (ATP-hydrolyzing)0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0Moderately InformativeDirect
Biological processCarbohydrate metabolism1Moderately InformativeInherited
Biological processStress response0InformativeDirect
Biological processSensory transduction0InformativeDirect
Biological processSporulation0InformativeDirect
Biological processVirulence0InformativeDirect
Biological processBiological rhythms9.345e-16InformativeDirect
Biological processNitrogen fixation0.0000000003363InformativeDirect
Biological processAntibiotic resistance0.0000622InformativeDirect
Biological processTwo-component regulatory system0Highly InformativeDirect
Biological processGlucose metabolism0.000000000000001398Highly InformativeDirect
Biological processEthylene signaling pathway0.00000000000002322Highly InformativeDirect
Cellular componentMembrane0.0000000336Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionDNA-binding0.0000000005645Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionChromophore0InformativeDirect
Molecular functionCopper0.0001287InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationReceptor0.0000000002691Moderately InformativeDirect
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationProtein phosphatase0.000000000000006994InformativeDirect
Post-translational modificationPhotoreceptor protein0Highly InformativeDirect
Post-translational modificationTopoisomerase0Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationS-nitrosylation0.00002015InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR003594 SSF55874 Protein matches
Abstract

This domain is found in several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases [PubMed15105144], heat shock protein HSP90 [PubMed15292259, PubMed14718169, PubMed15217611], phytochrome-like ATPases and DNA mismatch repair proteins.

More information about this protein can be found at Protein of the Month: DNA Topoisomerase.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 23 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 23 hidden Markov models representing the ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]