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  Home > SCOP hierarchy > Acyl-CoA N-acyltransferases (Nat) superfamily


Acyl-CoA N-acyltransferases (Nat) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Acyl-CoA N-acyltransferases (Nat) [ 55728]
Superfamily:   Acyl-CoA N-acyltransferases (Nat) [ 55729] (10)
Families:   N-acetyl transferase, NAT [ 55730] (57)
  N-myristoyl transferase, NMT [ 55748]
  Autoinducer synthetase [ 75508] (2)
  FemXAB nonribosomal peptidyltransferases [ 82749] (3)
  Hypothetical protein cg14615-pa [ 103179]
  LFTR-like [ 143711]
  Ornithine decarboxylase antizyme-like [ 143714]
  AstA-like [ 143717]
  Aq 1966-like [ 143720]
  EF1021-like [ 160644] (3)

Superfamily statistics
Genomes (2,440) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 71,695 213,696 112
Proteins 69,274 206,769 104

 Functional annotation
General category Metabolism
Detailed category Transferases

Document: Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process2.093e-050Least InformativeDirect
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.34191Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.57311Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)biosynthetic process0.27360.8757Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.29921Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.003630.09849Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.010620.0004147Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)cellular protein modification process3.484e-090Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process1.276e-070.0005416Moderately InformativeDirect
Biological Process (BP)cellular response to chemical stimulus0.010870.8178Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0093980.1565Moderately InformativeInherited
Biological Process (BP)response to organic substance0.40791Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus1.803e-050.06095Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.61541Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.97731Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.0061220.0283Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process3.662e-060.001361Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process7.859e-070.002764Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process4.319e-050.01933Moderately InformativeInherited
Biological Process (BP)organelle organization0.51221.504e-07Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process11Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.95631Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.87071Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.10581Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.51011Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process1.961e-086.081e-13InformativeDirect
Biological Process (BP)response to organic nitrogen1.006e-090.0001277InformativeDirect
Biological Process (BP)regulation of hormone levels1.581e-119.425e-09InformativeDirect
Biological Process (BP)cellular amide metabolic process1.987e-113.488e-11InformativeDirect
Biological Process (BP)chromosome organization6.972e-070InformativeDirect
Biological Process (BP)cellular response to nitrogen compound8.655e-141.341e-07InformativeDirect
Biological Process (BP)cellular response to oxygen-containing compound7.075e-080.0006783InformativeDirect
Biological Process (BP)response to organic cyclic compound4.338e-080.001697InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus4.132e-050.007611InformativeInherited
Biological Process (BP)cellular macromolecular complex assembly0.13160.462InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.0022440InformativeInherited
Biological Process (BP)nucleotide biosynthetic process0.012560.1776InformativeInherited
Biological Process (BP)DNA metabolic process0.75130.8617InformativeInherited
Biological Process (BP)embryonic morphogenesis1.614e-070.004596InformativeInherited
Biological Process (BP)amino sugar metabolic process5.964e-101.576e-08Highly InformativeDirect
Biological Process (BP)DNA packaging1.191e-055.019e-06Highly InformativeDirect
Biological Process (BP)polyamine metabolic process1.053e-140Highly InformativeDirect
Biological Process (BP)chromosome segregation7.12e-050.0008435Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process5.304e-084.164e-06Highly InformativeDirect
Biological Process (BP)response to toxic substance2.123e-081.084e-10Highly InformativeDirect
Biological Process (BP)response to purine-containing compound00Highly InformativeDirect
Biological Process (BP)histone modification0.00010860Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification8.044e-050Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process00Highly InformativeDirect
Biological Process (BP)hormone biosynthetic process00Highly InformativeDirect
Biological Process (BP)cellular response to organic cyclic compound1.628e-142.659e-08Highly InformativeDirect
Biological Process (BP)chromatin assembly or disassembly0.13531Highly InformativeInherited
Biological Process (BP)internal protein amino acid acetylation11Highly InformativeInherited
Biological Process (BP)gastrulation1.254e-130.003242Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.18210.0006028Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups00InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.0043057.27e-05InformativeInherited
Molecular Function (MF)acetyltransferase activity00Highly InformativeDirect
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex10.2972Least InformativeInherited
Cellular Component (CC)perinuclear region of cytoplasm7.366e-141.069e-07Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0004147 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.8757 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.09849 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 1.504e-07 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0005416 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.8178 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.1565 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.06095 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.0283 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.001361 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.002764 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.01933 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.718 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 6.081e-13 Informative Direct
Biological Process (BP) response to organic nitrogen 0.0001277 Informative Direct
Biological Process (BP) regulation of hormone levels 9.425e-09 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) cellular amide metabolic process 3.488e-11 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 1.341e-07 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0006783 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.001697 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.007611 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.462 Informative Inherited
Biological Process (BP) tube development 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.7197 Informative Inherited
Biological Process (BP) embryonic organ development 0.7263 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) proteolysis 1 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.004596 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.1776 Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.002712 Informative Inherited
Biological Process (BP) DNA metabolic process 0.8617 Informative Inherited
Biological Process (BP) chordate embryonic development 0.8799 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) amino sugar metabolic process 1.576e-08 Highly Informative Direct
Biological Process (BP) DNA packaging 5.019e-06 Highly Informative Direct
Biological Process (BP) arginine metabolic process 0.0007712 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 0 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.0008435 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 4.164e-06 Highly Informative Direct
Biological Process (BP) response to toxic substance 1.084e-10 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 3.535e-05 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) hormone biosynthetic process 0 Highly Informative Direct
Biological Process (BP) cellular response to organic cyclic compound 2.659e-08 Highly Informative Direct
Biological Process (BP) stem cell development 0.2348 Highly Informative Inherited
Biological Process (BP) chromatin assembly or disassembly 1 Highly Informative Inherited
Biological Process (BP) modification-dependent protein catabolic process 0.121 Highly Informative Inherited
Biological Process (BP) internal protein amino acid acetylation 1 Highly Informative Inherited
Biological Process (BP) serine family amino acid metabolic process 0.08401 Highly Informative Inherited
Biological Process (BP) tube formation 0.01706 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1673 Highly Informative Inherited
Biological Process (BP) epithelial tube morphogenesis 0.672 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.7423 Highly Informative Inherited
Biological Process (BP) gastrulation 0.003242 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) enzyme regulator activity 0.0006028 Moderately Informative Direct
Molecular Function (MF) enzyme inhibitor activity 7.27e-05 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) acetyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 2.591e-07 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring amino-acyl groups 1 Highly Informative Inherited
Molecular Function (MF) transcription factor binding transcription factor activity 0.01028 Highly Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.2972 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0005153 Moderately Informative Direct
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.004073 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 1 Informative Inherited
Cellular Component (CC) transcription elongation factor complex 1.708e-11 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 1.069e-07 Highly Informative Direct
Cellular Component (CC) spindle 0.2584 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Amino-acid N-acetyltransferase1.704e-07Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the central nervous system0Least InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.72Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.08071Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.3523Moderately InformativeInherited
Worm Phenotype (WP)somatic gonad development variant2.698e-06InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.00051Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0.1575Least InformativeInherited
Xenopus ANatomical entity (XAN)immune system0.001896Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spleen0.0007273InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Histone acetyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)blood and blood forming organs0.01966Least InformativeInherited
Drugbank ATC_code (DB)dermatologicals0.01171Moderately InformativeInherited
Drugbank ATC_code (DB)antiprotozoals8.416e-05InformativeDirect
Drugbank ATC_code (DB)other dermatologicals1InformativeInherited
Drugbank ATC_code (DB)liver therapy, lipotropics2.111e-05Highly InformativeDirect
Drugbank ATC_code (DB)eflornithine2.111e-05Highly InformativeDirect
Drugbank ATC_code (DB)eflornithine2.111e-05Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processAntibiotic resistance0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processBiological rhythms2.113e-08Highly InformativeDirect
Biological processDetoxification0.0001558Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus5.574e-05Least InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
DomainBromodomain1.588e-15Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationActivator3.757e-06Moderately InformativeDirect
Post-translational modificationDevelopmental protein0.5284Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationAcetylation1.569e-09Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism7.203e-15Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis2.565e-09Moderately InformativeDirect
UniPathway (UP)amino-acid degradation2.764e-08Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.02079Moderately InformativeInherited
UniPathway (UP)nucleotide metabolism0.2382Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)hormone metabolism6.827e-14InformativeDirect
UniPathway (UP)siderophore metabolism2.195e-08InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis2.979e-06InformativeDirect
UniPathway (UP)L-arginine degradation4.649e-06InformativeDirect
UniPathway (UP)putrescine metabolism0.002223InformativeInherited
UniPathway (UP)amine and polyamine degradation0.2193InformativeInherited
UniPathway (UP)amine and polyamine biosynthesis0.3707InformativeInherited
UniPathway (UP)ectoine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)melatonin biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis4.212e-11Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 81 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acyl-CoA N-acyltransferases (Nat) domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 81 hidden Markov models representing the Acyl-CoA N-acyltransferases (Nat) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

© Copyright 2013 The SUPERFAMILY authors and Julian Gough.