SUPERFAMILY 1.75 HMM library and genome assignments server

Acyl-CoA N-acyltransferases (Nat) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Acyl-CoA N-acyltransferases (Nat) [ 55728]
Superfamily:   Acyl-CoA N-acyltransferases (Nat) [ 55729] (10)
Families:   N-acetyl transferase, NAT [ 55730] (57)
  N-myristoyl transferase, NMT [ 55748]
  Autoinducer synthetase [ 75508] (2)
  FemXAB nonribosomal peptidyltransferases [ 82749] (3)
  Hypothetical protein cg14615-pa [ 103179]
  LFTR-like [ 143711]
  Ornithine decarboxylase antizyme-like [ 143714]
  AstA-like [ 143717]
  Aq 1966-like [ 143720]
  EF1021-like [ 160644] (3)


Superfamily statistics
Genomes (3,178) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 91,077 529,159 112
Proteins 88,039 498,894 104


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process0.00000075260Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)positive regulation of biological process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.25831Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.70531Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.9691Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.0018120.0000008837Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.68441Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)single-organism metabolic process10.01848Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)cellular protein modification process0.000000000019490Moderately InformativeDirect
Biological Process (BP)response to organic substance0.24211Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.10511Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.083270Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0040460.4611Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.00019320.2917Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process11Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.00056470.1136Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.011940.001435Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.33661Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.000021750.07208Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.000054730.02347Moderately InformativeInherited
Biological Process (BP)single-organism organelle organization0.033370.000000000000005526Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process11Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis11Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process0.0000013790.001452Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process11Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.96021Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.33171Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process0.0000000026060.0000000000001834InformativeDirect
Biological Process (BP)regulation of hormone levels0.0000000000070020.00000001708InformativeDirect
Biological Process (BP)peptidyl-amino acid modification0.000000074560InformativeDirect
Biological Process (BP)amide biosynthetic process0.0000000000044170InformativeDirect
Biological Process (BP)chromosome organization0.00000000091940InformativeDirect
Biological Process (BP)cellular response to nitrogen compound0.0000000000018670.0000133InformativeDirect
Biological Process (BP)response to organonitrogen compound0.000000010430.00304InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound0.0000023290.008324InformativeInherited
Biological Process (BP)response to organic cyclic compound0.0000002550.01291InformativeInherited
Biological Process (BP)peptide metabolic process0.012710.0582InformativeInherited
Biological Process (BP)positive regulation of catabolic process0.17150.6374InformativeInherited
Biological Process (BP)cell cycle process0.32450.9719InformativeInherited
Biological Process (BP)cell division0.075650.9041InformativeInherited
Biological Process (BP)cellular macromolecular complex assembly0.29840.6812InformativeInherited
Biological Process (BP)nucleotide biosynthetic process0.033410.3557InformativeInherited
Biological Process (BP)embryonic morphogenesis0.0000034110.03134InformativeInherited
Biological Process (BP)mitotic cell cycle0.070220.7151InformativeInherited
Biological Process (BP)organelle fission0.0052881InformativeInherited
Biological Process (BP)amino sugar metabolic process0.000000000088290.000000001491Highly InformativeDirect
Biological Process (BP)polyamine metabolic process0.00000000005030.0000000000008244Highly InformativeDirect
Biological Process (BP)chromosome segregation0.0000000068620.000009341Highly InformativeDirect
Biological Process (BP)circadian rhythm00.0000000000004052Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process0.000000066720.00001326Highly InformativeDirect
Biological Process (BP)response to toxic substance0.00000093290.000002387Highly InformativeDirect
Biological Process (BP)response to purine-containing compound00.00000000000002753Highly InformativeDirect
Biological Process (BP)histone modification0.00000000000033290Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification0.00000018950Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process00.00000000000009454Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process00Highly InformativeDirect
Biological Process (BP)hormone biosynthetic process00Highly InformativeDirect
Biological Process (BP)internal protein amino acid acetylation11Highly InformativeInherited
Biological Process (BP)nuclear division0.0025470.1716Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.10680.000007655Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups00InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.0022790.00004445InformativeInherited
Molecular Function (MF)acetyltransferase activity00Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex10.5188Least InformativeInherited
Cellular Component (CC)transferase complex0.00084070Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.23211Moderately InformativeInherited
Cellular Component (CC)protein acetyltransferase complex0.00000000000013410Highly InformativeDirect
Cellular Component (CC)perinuclear region of cytoplasm0.0000000000017080.000005042Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0000008837 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) positive regulation of biological process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.01848 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0 Moderately Informative Direct
Biological Process (BP) single-organism organelle organization 0.000000000000005526 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.4611 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.2917 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.1136 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.8258 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.9537 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.07208 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.02347 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.001435 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.592 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.001452 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 0.0000000000001834 Informative Direct
Biological Process (BP) regulation of hormone levels 0.00000001708 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) amide biosynthetic process 0 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 0.0000133 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0.869 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.6794 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.5026 Informative Inherited
Biological Process (BP) positive regulation of RNA metabolic process 0.5105 Informative Inherited
Biological Process (BP) cell division 0.9041 Informative Inherited
Biological Process (BP) organelle fission 1 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.00304 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.008324 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.01291 Informative Inherited
Biological Process (BP) peptide metabolic process 0.0582 Informative Inherited
Biological Process (BP) positive regulation of catabolic process 0.6374 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.5667 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.1134 Informative Inherited
Biological Process (BP) positive regulation of transport 0.221 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.007453 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) proteolysis 1 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 1 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Informative Inherited
Biological Process (BP) cell cycle process 0.9719 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.6812 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.3557 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tube development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.03134 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.7151 Informative Inherited
Biological Process (BP) amino sugar metabolic process 0.000000001491 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 0.0000000000008244 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.000009341 Highly Informative Direct
Biological Process (BP) circadian rhythm 0.0000000000004052 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 0.00001326 Highly Informative Direct
Biological Process (BP) response to toxic substance 0.000002387 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 0.00000000000002753 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0 Highly Informative Direct
Biological Process (BP) positive regulation of intracellular transport 0.000005429 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 0.00000000000009454 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 0.0004458 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) hormone biosynthetic process 0 Highly Informative Direct
Biological Process (BP) artery morphogenesis 0.0007818 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.004271 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 0.5255 Highly Informative Inherited
Biological Process (BP) peptide biosynthetic process 0.02473 Highly Informative Inherited
Biological Process (BP) ubiquitin-dependent protein catabolic process 0.1938 Highly Informative Inherited
Biological Process (BP) internal protein amino acid acetylation 1 Highly Informative Inherited
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.001293 Highly Informative Inherited
Biological Process (BP) nuclear division 0.1716 Highly Informative Inherited
Biological Process (BP) serine family amino acid metabolic process 0.188 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1247 Highly Informative Inherited
Biological Process (BP) neural tube development 0.04327 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.01116 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.7051 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) enzyme regulator activity 0.000007655 Moderately Informative Direct
Molecular Function (MF) enzyme inhibitor activity 0.00004445 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) acetyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 0.000001113 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring amino-acyl groups 1 Highly Informative Inherited
Molecular Function (MF) transcription factor binding transcription factor activity 0.01545 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.5188 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0001744 Moderately Informative Direct
Cellular Component (CC) transferase complex 0 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.004339 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0 Informative Direct
Cellular Component (CC) chromosome 0.02858 Informative Inherited
Cellular Component (CC) protein acetyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 0.000005042 Highly Informative Direct
Cellular Component (CC) chromatin 0.008959 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.08415 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Amino-acid N-acetyltransferase0.0000001704Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09283Least InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.01586Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality0.5876InformativeInherited
Mammalian Phenotype (MP)embryonic lethality between implantation and placentation0.06019Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.72Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.08071Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.3523Moderately InformativeInherited
Worm Phenotype (WP)somatic gonad development variant0.000002698InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.00051Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0.1569Least InformativeInherited
Xenopus ANatomical entity (XAN)immune system0.001895Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spleen0.0007241InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)blood and blood forming organs0.0104Least InformativeInherited
Drugbank ATC_code (DB)alimentary tract and metabolism0.3602Least InformativeInherited
Drugbank ATC_code (DB)iron preparations0.0004716InformativeDirect
Drugbank ATC_code (DB)other dermatological preparations1InformativeInherited
Drugbank ATC_code (DB)liver therapy, lipotropics0.000001521Highly InformativeDirect
Drugbank ATC_code (DB)eflornithine0.000001521Highly InformativeDirect
Drugbank ATC_code (DB)eflornithine0.000001521Highly InformativeDirect
Drugbank ATC_code (DB)ferrous glycine sulfate0.0000635Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processAntibiotic resistance0InformativeDirect
Biological processBiological rhythms0.0000001586InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processPolyamine biosynthesis0.0000002146Highly InformativeDirect
Biological processDetoxification0.0001633Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus0.00007858Least InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
DomainBromodomain0.000000000000002428Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationActivator0.0000007049Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationAcetylation0.000000002662Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0.00000000000000246Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis0.000000002025Moderately InformativeDirect
UniPathway (UP)amino-acid degradation0.00000005294Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.03255Moderately InformativeInherited
UniPathway (UP)nucleotide metabolism0.2845Moderately InformativeInherited
UniPathway (UP)energy metabolism0.3146Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)hormone biosynthesis0InformativeDirect
UniPathway (UP)siderophore metabolism0.00000003107InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0.000004439InformativeDirect
UniPathway (UP)L-arginine degradation0.000006961InformativeDirect
UniPathway (UP)putrescine metabolism0.001078InformativeInherited
UniPathway (UP)amine and polyamine degradation0.1508InformativeInherited
UniPathway (UP)amine and polyamine biosynthesis0.4748InformativeInherited
UniPathway (UP)ectoine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)melatonin biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis0.00000000006651Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 81 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acyl-CoA N-acyltransferases (Nat) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 81 hidden Markov models representing the Acyl-CoA N-acyltransferases (Nat) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]