SUPERFAMILY 1.75 HMM library and genome assignments server


SCP-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   SCP-like [ 55717]
Superfamily:   SCP-like [ 55718] (4)
Families:   Sterol carrier protein, SCP [ 55719] (3)
  Micothiol-dependent maleylpyruvate isomerase C-terminal domain-like [ 160614]
  Alkylsulfatase C-terminal domain-like [ 160617]
  EF1021 C-terminal domain-like [ 160620] (3)


Superfamily statistics
Genomes (1,720) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,187 20,649 12
Proteins 4,131 20,567 12


Functional annotation
General category Metabolism
Detailed category Coenzyme metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.07022 Least Informative Inherited
Biological Process (BP) cellular catabolic process 0.05345 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.002173 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.01341 Moderately Informative Inherited
Biological Process (BP) lipid catabolic process 9.757e-07 Informative Direct
Biological Process (BP) fatty acid metabolic process 6.205e-06 Informative Direct
Biological Process (BP) carboxylic acid catabolic process 0.0001305 Informative Direct
Biological Process (BP) fatty acid catabolic process 3.937e-09 Highly Informative Direct
Biological Process (BP) lipid modification 2.554e-08 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.02552 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.3199 Least Informative Inherited
Cellular Component (CC) microbody 0 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups2.703e-09Moderately InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)alimentary system0Least InformativeDirect
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)intestine0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ovary0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)gamete0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.01033Least InformativeInherited
Enzyme Commission (EC)Lyases0.01835Least InformativeInherited
Enzyme Commission (EC)Acyltransferases1.193e-08Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors2.494e-05Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0.001695Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1.614e-05InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.001268Least InformativeInherited
Biological processLipid transport5.523e-12InformativeDirect
Cellular componentMitochondrion0.0001178Moderately InformativeDirect
Cellular componentPeroxisome0InformativeDirect
Coding sequence diversityAlternative initiation4.455e-09Moderately InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Molecular functionNADP4.704e-07InformativeDirect
Post-translational modificationTransferase0.1359Least InformativeInherited
Post-translational modificationOxidoreductase2.427e-07Moderately InformativeDirect
Post-translational modificationAcyltransferase1.375e-09InformativeDirect
Post-translational modificationAcetylation9.083e-16Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)fatty acid metabolism0Moderately InformativeDirect
UniPathway (UP)fatty acid degradation0.0008021InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a SCP-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the SCP-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]