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Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001

	GO term	FDR (singleton)	FDR (all)	IC level	SDFO level	Annotation (direct or inherited)
Biological Process (BP)	nucleobase-containing compound metabolic process	3.476e-08	5.148e-05	0.7305	--	DIRECT
Biological Process (BP)	nucleoside diphosphate phosphorylation	1.658e-10	1.348e-14	2.699	--	DIRECT
Biological Process (BP)	GTP biosynthetic process	2.614e-14	0	2.699	--	DIRECT
Biological Process (BP)	phosphorus metabolic process	4.936e-06	0.0003202	0.8013	--	DIRECT
Biological Process (BP)	integrin-mediated signaling pathway	5.073e-13	1.346e-08	2.699	--	DIRECT
Biological Process (BP)	purine nucleoside triphosphate biosynthetic process	2.316e-06	3.058e-05	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleotide biosynthetic process	0.0001795	0.0004566	1.745	--	DIRECT
Biological Process (BP)	nucleoside biosynthetic process	0.0001735	7.48e-05	1.62	--	DIRECT
Biological Process (BP)	ribonucleoside triphosphate biosynthetic process	2.792e-05	0.0004577	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleoside triphosphate biosynthetic process	6.273e-07	3.463e-06	2.222	--	DIRECT
Biological Process (BP)	cellular nitrogen compound metabolic process	3.073e-06	0.0009285	0.585	--	DIRECT
Biological Process (BP)	nucleobase-containing compound biosynthetic process	1.016e-06	8.775e-06	1.167	--	DIRECT
Biological Process (BP)	purine nucleoside biosynthetic process	0.0001855	4.442e-05	1.658	--	DIRECT
Biological Process (BP)	ribonucleoside biosynthetic process	1.11e-07	1.493e-07	1.62	--	DIRECT
Biological Process (BP)	regulation of programmed cell death	1.394e-05	0.0001255	1.319	--	DIRECT
Biological Process (BP)	small molecule metabolic process	6.768e-05	2.888e-05	0.6421	--	DIRECT
Biological Process (BP)	GTP metabolic process	6.393e-06	2.077e-06	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleoside metabolic process	9.175e-05	0.0002728	1.553	--	DIRECT
Biological Process (BP)	purine ribonucleoside biosynthetic process	3.759e-08	4.224e-08	1.658	--	DIRECT
Biological Process (BP)	nucleotide phosphorylation	1.195e-14	0	2.699	--	DIRECT
Biological Process (BP)	regulation of epithelial cell proliferation	5.029e-08	1.622e-05	1.921	--	DIRECT
Biological Process (BP)	organophosphate biosynthetic process	3.636e-11	1.154e-11	1.155	--	DIRECT
Biological Process (BP)	guanosine-containing compound biosynthetic process	4.424e-12	8.402e-13	2.699	--	DIRECT
Biological Process (BP)	nucleoside phosphate biosynthetic process	3.099e-15	1.231e-09	1.444	--	DIRECT
Biological Process (BP)	glycosyl compound metabolic process	0.0001094	2.932e-05	1.377	--	DIRECT
Biological Process (BP)	purine-containing compound metabolic process	0.003898	0.003364	1.357	--	INHERITED FROM: guanosine-containing compound biosynthetic process || GTP metabolic process || purine-containing compound biosynthetic process || purine ribonucleoside metabolic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	positive regulation of cell proliferation	0.02676	0.008941	1.658	--	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	positive regulation of biological process	0.0003584	0.3899	0.8182	--	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	regulation of biological process	1	1	0.4486	--	INHERITED FROM: regulation of epithelial cell proliferation || regulation of programmed cell death || integrin-mediated signaling pathway || positive regulation of epithelial cell proliferation || regulation of apoptotic process
Biological Process (BP)	biological regulation	0.0004273	0.01915	0.4202	--	INHERITED FROM: regulation of epithelial cell proliferation || regulation of programmed cell death || integrin-mediated signaling pathway || positive regulation of epithelial cell proliferation || regulation of apoptotic process
Biological Process (BP)	reproductive process	0.008731	0.03472	1.143	--	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	multicellular organism reproduction	0.001382	0.001614	1.301	--	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	phosphorylation	0.003879	0.1859	1.398	--	INHERITED FROM: nucleotide phosphorylation || nucleoside diphosphate phosphorylation
Biological Process (BP)	biological_process	1	1	0	--	INHERITED FROM: GTP metabolic process || multicellular organismal reproductive process || nucleotide phosphorylation || guanosine-containing compound metabolic process || ribonucleoside biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || purine-containing compound biosynthetic process || nucleobase-containing compound metabolic process || purine nucleoside biosynthetic process || heterocycle biosynthetic process || phosphate-containing compound metabolic process || nucleoside diphosphate metabolic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound metabolic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || cellular nitrogen compound metabolic process || GTP biosynthetic process || nucleoside triphosphate biosynthetic process || regulation of epithelial cell proliferation || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside diphosphate phosphorylation || nucleobase-containing small molecule metabolic process || phosphorus metabolic process || nucleoside phosphate biosynthetic process || glycosyl compound biosynthetic process || regulation of programmed cell death || integrin-mediated signaling pathway || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || organophosphate biosynthetic process || positive regulation of epithelial cell proliferation || organic cyclic compound biosynthetic process || heterocycle metabolic process || small molecule metabolic process || purine ribonucleotide biosynthetic process || purine ribonucleoside biosynthetic process || regulation of apoptotic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process
Biological Process (BP)	organonitrogen compound metabolic process	0.08526	0.07683	0.699	--	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || purine-containing compound biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	primary metabolic process	0.03161	0.0756	0.2976	--	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || nucleobase-containing compound biosynthetic process
Biological Process (BP)	metabolic process	0.1885	0.2032	0.2411	--	INHERITED FROM: GTP metabolic process || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || heterocycle metabolic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || organic cyclic compound metabolic process || nucleoside diphosphate phosphorylation || small molecule metabolic process || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || phosphate-containing compound metabolic process || GTP biosynthetic process
Biological Process (BP)	cellular metabolic process	0.1097	0.1331	0.2708	--	INHERITED FROM: GTP metabolic process || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || heterocycle metabolic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || phosphate-containing compound metabolic process || GTP biosynthetic process
Biological Process (BP)	nucleoside phosphate metabolic process	0.001468	0.0008295	1.194	--	INHERITED FROM: GTP metabolic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || nucleotide phosphorylation || purine ribonucleotide biosynthetic process || nucleoside diphosphate metabolic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleoside diphosphate phosphorylation || nucleoside phosphate biosynthetic process || purine ribonucleoside triphosphate biosynthetic process
Biological Process (BP)	organic substance metabolic process	0.08712	0.2638	0.2676	--	INHERITED FROM: GTP metabolic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || organic cyclic compound metabolic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || GTP biosynthetic process
Biological Process (BP)	cellular process	0.1104	0.1432	0.1415	--	INHERITED FROM: GTP metabolic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || guanosine-containing compound metabolic process || ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || nucleobase-containing small molecule metabolic process || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || phosphate-containing compound metabolic process || integrin-mediated signaling pathway || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || organophosphate biosynthetic process || nucleoside diphosphate metabolic process || purine ribonucleoside triphosphate biosynthetic process || heterocycle metabolic process || purine ribonucleotide biosynthetic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || cellular nitrogen compound metabolic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process
Biological Process (BP)	nucleotide metabolic process	1	1	1.222	--	INHERITED FROM: GTP metabolic process || GTP biosynthetic process || nucleotide phosphorylation || purine ribonucleotide biosynthetic process || nucleoside diphosphate phosphorylation
Biological Process (BP)	regulation of cell death	0.0009458	0.001488	1.301	--	INHERITED FROM: regulation of programmed cell death || regulation of apoptotic process
Biological Process (BP)	cellular biosynthetic process	0.001947	0.006172	0.5498	--	INHERITED FROM: heterocycle biosynthetic process || ribonucleoside triphosphate biosynthetic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || cellular nitrogen compound biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	ribonucleoside triphosphate metabolic process	1	1	2	--	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process
Biological Process (BP)	purine nucleoside triphosphate metabolic process	1	1	1.921	--	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine nucleoside triphosphate biosynthetic process
Biological Process (BP)	organic substance biosynthetic process	0.002094	0.0209	0.5376	--	INHERITED FROM: ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || organophosphate biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	carbohydrate derivative biosynthetic process	0.002443	0.01031	1.222	--	INHERITED FROM: nucleoside biosynthetic process || guanosine-containing compound biosynthetic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process || ribonucleoside biosynthetic process
Biological Process (BP)	nucleoside metabolic process	0.01286	0.00803	1.444	--	INHERITED FROM: nucleoside biosynthetic process || guanosine-containing compound biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || ribonucleoside biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	purine nucleotide biosynthetic process	0.000455	0.001817	1.62	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	ribonucleotide biosynthetic process	0.006874	0.02437	1.745	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	ribose phosphate biosynthetic process	0.0007192	0.007702	1.699	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	cell communication	0.0299	0.01284	0.8477	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	cell surface receptor signaling pathway	4.783e-05	0.005812	1.237	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	signaling	0.007991	0.006881	0.8416	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	single-organism process	0.1553	0.5026	0.3316	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	single organism signaling	0.0159	0.006876	0.8601	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	cellular response to stimulus	0.01167	0.01782	0.7645	--	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	purine ribonucleotide metabolic process	0.5798	0.5819	1.62	--	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	ribonucleotide metabolic process	0.7216	0.8039	1.62	--	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	cellular aromatic compound metabolic process	1.741e-06	0.0007282	0.6271	Least Informative	DIRECT
Biological Process (BP)	heterocycle metabolic process	1.435e-06	0.0004978	0.6308	Least Informative	DIRECT
Biological Process (BP)	organic cyclic compound metabolic process	6.491e-06	0.0009004	0.5817	Least Informative	DIRECT
Biological Process (BP)	multicellular organismal process	0.1306	0.1839	0.6091	Least Informative	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	nitrogen compound metabolic process	4.968e-05	0.003077	0.5171	Least Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || cellular nitrogen compound biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || nucleobase-containing compound biosynthetic process
Biological Process (BP)	single-organism metabolic process	0.001223	0.001253	0.5376	Least Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || small molecule metabolic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || glycosyl compound metabolic process
Biological Process (BP)	biosynthetic process	0.002141	0.00583	0.52	Least Informative	INHERITED FROM: heterocycle biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || cellular nitrogen compound biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || organophosphate biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	regulation of cellular process	0.002472	0.02419	0.5317	Least Informative	INHERITED FROM: integrin-mediated signaling pathway || regulation of epithelial cell proliferation || positive regulation of epithelial cell proliferation || regulation of apoptotic process || regulation of programmed cell death
Biological Process (BP)	single-organism cellular process	0.3881	0.7426	0.3915	Least Informative	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	response to stimulus	0.2359	0.2509	0.5498	Least Informative	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	phosphate-containing compound metabolic process	3.407e-06	7.769e-05	0.8182	Moderately Informative	DIRECT
Biological Process (BP)	heterocycle biosynthetic process	1.203e-05	6.723e-05	0.9355	Moderately Informative	DIRECT
Biological Process (BP)	aromatic compound biosynthetic process	2.128e-06	6.134e-05	0.9747	Moderately Informative	DIRECT
Biological Process (BP)	organophosphate metabolic process	1.251e-07	1.256e-07	0.9914	Moderately Informative	DIRECT
Biological Process (BP)	cellular nitrogen compound biosynthetic process	1.463e-05	8.516e-05	0.9136	Moderately Informative	DIRECT
Biological Process (BP)	nucleobase-containing small molecule metabolic process	3.208e-10	9.122e-12	1.086	Moderately Informative	DIRECT
Biological Process (BP)	organic cyclic compound biosynthetic process	2.333e-05	0.0001001	0.8928	Moderately Informative	DIRECT
Biological Process (BP)	positive regulation of cellular process	0.0001452	0.312	0.9066	Moderately Informative	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	reproduction	0.01812	0.0713	1.097	Moderately Informative	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	organonitrogen compound biosynthetic process	0.05131	0.06711	0.8861	Moderately Informative	INHERITED FROM: nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || purine-containing compound biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process || ribonucleoside biosynthetic process
Biological Process (BP)	carbohydrate derivative metabolic process	0.001523	0.0004861	1.018	Moderately Informative	INHERITED FROM: nucleoside biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || purine ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || guanosine-containing compound metabolic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process || ribonucleoside biosynthetic process
Biological Process (BP)	signal transduction	0.06689	0.005373	0.9914	Moderately Informative	INHERITED FROM: integrin-mediated signaling pathway
Biological Process (BP)	regulation of apoptotic process	7.487e-06	5.663e-05	1.337	Informative	DIRECT
Biological Process (BP)	multicellular organismal reproductive process	0.000454	0.0008032	1.337	Informative	DIRECT
Biological Process (BP)	purine-containing compound biosynthetic process	1.539e-05	3.462e-05	1.523	Informative	DIRECT
Biological Process (BP)	glycosyl compound biosynthetic process	5.981e-05	5.141e-05	1.585	Informative	DIRECT
Biological Process (BP)	purine nucleoside metabolic process	0.5334	0.6725	1.553	Informative	INHERITED FROM: guanosine-containing compound biosynthetic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || guanosine-containing compound metabolic process || purine nucleoside biosynthetic process
Biological Process (BP)	ribonucleoside metabolic process	0.8768	1	1.495	Informative	INHERITED FROM: guanosine-containing compound biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || ribonucleoside biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process
Biological Process (BP)	regulation of cell proliferation	0.009477	0.1167	1.42	Informative	INHERITED FROM: positive regulation of epithelial cell proliferation || regulation of epithelial cell proliferation
Biological Process (BP)	nucleoside triphosphate metabolic process	0.009721	0.002439	1.745	Informative	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine nucleoside triphosphate biosynthetic process || nucleoside triphosphate biosynthetic process
Biological Process (BP)	purine nucleotide metabolic process	0.3072	0.3497	1.553	Informative	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	ribose phosphate metabolic process	0.04389	0.07101	1.585	Informative	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	nucleotide biosynthetic process	0.0003043	0.002509	1.444	Informative	INHERITED FROM: nucleoside diphosphate phosphorylation || GTP biosynthetic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	nucleoside diphosphate metabolic process	6.629e-08	4.368e-10	2.222	Highly Informative	DIRECT
Biological Process (BP)	nucleoside triphosphate biosynthetic process	7.445e-11	1.639e-11	2.097	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of epithelial cell proliferation	8.411e-09	1.445e-06	2	Highly Informative	DIRECT
Biological Process (BP)	guanosine-containing compound metabolic process	1.141e-05	3.612e-06	2.097	Highly Informative	DIRECT
Biological Process (BP)	purine ribonucleoside triphosphate metabolic process	0.8546	1	2	Highly Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process
Molecular Function (MF)	nucleoside binding	0.000182	1.064e-05	1.775	--	DIRECT
Molecular Function (MF)	purine nucleoside binding	4.593e-07	1.03e-05	1.775	--	DIRECT
Molecular Function (MF)	nucleoside diphosphate kinase activity	0	0	2.679	--	DIRECT
Molecular Function (MF)	phosphotransferase activity, phosphate group as acceptor	0	0	2.377	--	DIRECT
Molecular Function (MF)	purine nucleotide binding	5.094e-07	1.527e-05	1.679	--	DIRECT
Molecular Function (MF)	adenyl nucleotide binding	2.831e-10	9.077e-07	1.833	--	DIRECT
Molecular Function (MF)	ribonucleoside binding	4.395e-07	1.022e-05	1.775	--	DIRECT
Molecular Function (MF)	purine ribonucleoside binding	4.332e-07	1.01e-05	1.775	--	DIRECT
Molecular Function (MF)	ribonucleotide binding	6.325e-07	1.663e-05	1.599	--	DIRECT
Molecular Function (MF)	purine ribonucleotide binding	4.395e-07	1.378e-05	1.679	--	DIRECT
Molecular Function (MF)	adenyl ribonucleotide binding	2.386e-10	8.56e-07	1.833	--	DIRECT
Molecular Function (MF)	small molecule binding	6.714e-05	0.0001945	1.317	--	DIRECT
Molecular Function (MF)	nucleoside phosphate binding	0.001376	9.82e-05	1.448	--	INHERITED FROM: adenyl ribonucleotide binding || purine nucleotide binding || ribonucleotide binding || ATP binding || purine ribonucleotide binding || nucleotide binding || adenyl nucleotide binding
Molecular Function (MF)	catalytic activity	0.02327	0.1079	0.2686	--	INHERITED FROM: phosphotransferase activity, phosphate group as acceptor || transferase activity || kinase activity || transferase activity, transferring phosphorus-containing groups || nucleoside diphosphate kinase activity || nucleobase-containing compound kinase activity
Molecular Function (MF)	purine ribonucleoside triphosphate binding	0.001734	0.001435	1.775	--	INHERITED FROM: ATP binding
Molecular Function (MF)	ion binding	0.008084	0.0009748	0.8334	--	INHERITED FROM: ATP binding
Molecular Function (MF)	molecular_function	1	1	0	--	INHERITED FROM: nucleoside binding || ribonucleoside binding || phosphotransferase activity, phosphate group as acceptor || ribonucleotide binding || adenyl nucleotide binding || transferase activity, transferring phosphorus-containing groups || purine ribonucleoside binding || adenyl ribonucleotide binding || nucleotide binding || small molecule binding || ATP binding || transferase activity || purine nucleotide binding || purine nucleoside binding || kinase activity || purine ribonucleotide binding || nucleoside diphosphate kinase activity || nucleobase-containing compound kinase activity
Molecular Function (MF)	transferase activity	1.821e-08	1.467e-07	0.7491	Least Informative	DIRECT
Molecular Function (MF)	binding	0.0212	0.5809	0.3952	Least Informative	INHERITED FROM: purine ribonucleoside binding || purine ribonucleotide binding || purine nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ribonucleoside binding || adenyl nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || small molecule binding || ATP binding
Molecular Function (MF)	transferase activity, transferring phosphorus-containing groups	3.816e-15	7.403e-12	1.134	Moderately Informative	DIRECT
Molecular Function (MF)	organic cyclic compound binding	0.002167	0.1637	0.846	Moderately Informative	INHERITED FROM: purine ribonucleoside binding || ribonucleoside binding || purine nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || adenyl nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ATP binding || purine ribonucleotide binding
Molecular Function (MF)	heterocyclic compound binding	0.001473	0.1517	0.8932	Moderately Informative	INHERITED FROM: purine ribonucleoside binding || ribonucleoside binding || purine nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || adenyl nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ATP binding || purine ribonucleotide binding
Molecular Function (MF)	anion binding	7.544e-06	0.07536	1.076	Moderately Informative	INHERITED FROM: ATP binding
Molecular Function (MF)	nucleotide binding	2.716e-06	9.82e-05	1.448	Informative	DIRECT
Molecular Function (MF)	kinase activity	0	3.487e-13	1.474	Informative	DIRECT
Molecular Function (MF)	ATP binding	1.013e-10	4.93e-07	1.98	Highly Informative	DIRECT
Molecular Function (MF)	nucleobase-containing compound kinase activity	0	0	2.201	Highly Informative	DIRECT
Cellular Component (CC)	mitochondrion	5.707e-08	7.35e-14	0.7422	--	DIRECT
Cellular Component (CC)	cell-substrate adherens junction	2.199e-14	4.804e-09	2.241	--	DIRECT
Cellular Component (CC)	anchoring junction	4.051e-12	1.723e-06	2.064	--	DIRECT
Cellular Component (CC)	cellular_component	0.001514	0.016	0	--	INHERITED FROM: mitochondrion || cell-substrate junction || lamellipodium || cell leading edge || ruffle || anchoring junction || cell-substrate adherens junction
Cellular Component (CC)	cell	8.168e-07	0.001026	0.08068	--	INHERITED FROM: mitochondrion || lamellipodium || cell leading edge || ruffle
Cellular Component (CC)	cell part	7.992e-07	0.001014	0.08068	--	INHERITED FROM: mitochondrion || lamellipodium || cell leading edge || ruffle
Cellular Component (CC)	intracellular	0.03262	0.006349	0.1266	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	cytoplasm	0.102	0.00694	0.2515	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	organelle	1.257e-05	0.006728	0.1836	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	membrane-bounded organelle	0.07388	0.3325	0.2912	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular organelle	0.2963	0.9381	0.1875	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular part	0.02822	0.005013	0.1266	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular membrane-bounded organelle	0.07302	0.3216	0.2961	Least Informative	INHERITED FROM: mitochondrion
Cellular Component (CC)	cytoplasmic part	0.3675	0.1588	0.2605	Least Informative	INHERITED FROM: mitochondrion
Cellular Component (CC)	cell projection	4.187e-05	0.001775	1.079	Moderately Informative	INHERITED FROM: ruffle || lamellipodium
Cellular Component (CC)	cell leading edge	5.392e-10	1.685e-07	1.638	Informative	DIRECT
Cellular Component (CC)	cell junction	7.26e-07	0.001279	1.5	Informative	INHERITED FROM: cell-substrate adherens junction || cell-substrate junction || anchoring junction
Cellular Component (CC)	ruffle	1.787e-09	4.338e-09	2.241	Highly Informative	DIRECT
Cellular Component (CC)	lamellipodium	3.553e-08	2.742e-08	1.763	Highly Informative	DIRECT
Cellular Component (CC)	cell-substrate junction	2.199e-14	1.315e-08	2.241	Highly Informative	DIRECT
Cellular Component (CC)	adherens junction	1	1.221e-06	2.064	Highly Informative	INHERITED FROM: cell-substrate adherens junction

Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001

	GO term	FDR (all)	IC level	SDFO level	Annotation (direct or inherited)
Biological Process (BP)	nucleobase-containing compound metabolic process	5.148e-05	0.7305	--	DIRECT
Biological Process (BP)	nucleoside diphosphate phosphorylation	1.348e-14	2.699	--	DIRECT
Biological Process (BP)	GTP biosynthetic process	0	2.699	--	DIRECT
Biological Process (BP)	nucleoside phosphate metabolic process	0.0008295	1.194	--	DIRECT
Biological Process (BP)	phosphorus metabolic process	0.0003202	0.8013	--	DIRECT
Biological Process (BP)	integrin-mediated signaling pathway	1.346e-08	2.699	--	DIRECT
Biological Process (BP)	determination of left/right symmetry	1.55e-08	2.699	--	DIRECT
Biological Process (BP)	brain development	2.453e-05	1.658	--	DIRECT
Biological Process (BP)	purine nucleoside triphosphate biosynthetic process	3.058e-05	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleotide biosynthetic process	0.0004566	1.745	--	DIRECT
Biological Process (BP)	nucleoside biosynthetic process	7.48e-05	1.62	--	DIRECT
Biological Process (BP)	ribonucleoside triphosphate biosynthetic process	0.0004577	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleoside triphosphate biosynthetic process	3.463e-06	2.222	--	DIRECT
Biological Process (BP)	specification of symmetry	7.814e-08	2.699	--	DIRECT
Biological Process (BP)	determination of bilateral symmetry	7.342e-08	2.699	--	DIRECT
Biological Process (BP)	cellular nitrogen compound metabolic process	0.0009285	0.585	--	DIRECT
Biological Process (BP)	nucleobase-containing compound biosynthetic process	8.775e-06	1.167	--	DIRECT
Biological Process (BP)	purine nucleoside biosynthetic process	4.442e-05	1.658	--	DIRECT
Biological Process (BP)	ribonucleoside biosynthetic process	1.493e-07	1.62	--	DIRECT
Biological Process (BP)	regulation of programmed cell death	0.0001255	1.319	--	DIRECT
Biological Process (BP)	small molecule metabolic process	2.888e-05	0.6421	--	DIRECT
Biological Process (BP)	GTP metabolic process	2.077e-06	2.222	--	DIRECT
Biological Process (BP)	purine ribonucleoside metabolic process	0.0002728	1.553	--	DIRECT
Biological Process (BP)	purine ribonucleoside biosynthetic process	4.224e-08	1.658	--	DIRECT
Biological Process (BP)	nucleotide phosphorylation	0	2.699	--	DIRECT
Biological Process (BP)	regulation of epithelial cell proliferation	1.622e-05	1.921	--	DIRECT
Biological Process (BP)	organophosphate biosynthetic process	1.154e-11	1.155	--	DIRECT
Biological Process (BP)	guanosine-containing compound biosynthetic process	8.402e-13	2.699	--	DIRECT
Biological Process (BP)	nucleoside phosphate biosynthetic process	1.231e-09	1.444	--	DIRECT
Biological Process (BP)	glycosyl compound metabolic process	2.932e-05	1.377	--	DIRECT
Biological Process (BP)	purine-containing compound metabolic process	0.003364	1.357	--	INHERITED FROM: guanosine-containing compound biosynthetic process || GTP metabolic process || purine-containing compound biosynthetic process || purine ribonucleoside metabolic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	single-organism process	0.5026	0.3316	--	INHERITED FROM: protein localization to membrane || left/right pattern formation || receptor clustering || ciliary receptor clustering involved in smoothened signaling pathway || microtubule-based movement || specification of symmetry || integrin-mediated signaling pathway || determination of bilateral symmetry || cytoskeleton-dependent intracellular transport || central nervous system development || determination of left/right symmetry || cellular component movement || epithelial cilium movement || cilium movement || intraflagellar transport || smoothened signaling pathway || brain development || microtubule-based process
Biological Process (BP)	membrane organization	0.001953	1.523	--	INHERITED FROM: protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || receptor clustering
Biological Process (BP)	regionalization	0.3551	2.222	--	INHERITED FROM: left/right pattern formation
Biological Process (BP)	negative regulation of biological process	0.4297	0.8665	--	INHERITED FROM: negative regulation of cell death
Biological Process (BP)	positive regulation of cell proliferation	0.008941	1.658	--	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	positive regulation of biological process	0.3899	0.8182	--	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	regulation of biological process	1	0.4486	--	INHERITED FROM: regulation of epithelial cell proliferation || ciliary receptor clustering involved in smoothened signaling pathway || negative regulation of cell death || regulation of programmed cell death || integrin-mediated signaling pathway || positive regulation of epithelial cell proliferation || regulation of apoptotic process || smoothened signaling pathway
Biological Process (BP)	biological regulation	0.01915	0.4202	--	INHERITED FROM: regulation of epithelial cell proliferation || ciliary receptor clustering involved in smoothened signaling pathway || negative regulation of cell death || regulation of programmed cell death || integrin-mediated signaling pathway || positive regulation of epithelial cell proliferation || regulation of apoptotic process || smoothened signaling pathway
Biological Process (BP)	reproductive process	0.03472	1.143	--	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	multicellular organism reproduction	0.001614	1.301	--	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	phosphorylation	0.1859	1.398	--	INHERITED FROM: nucleotide phosphorylation || nucleoside diphosphate phosphorylation
Biological Process (BP)	biological_process	1	0	--	INHERITED FROM: GTP metabolic process || multicellular organismal reproductive process || nucleotide phosphorylation || left/right pattern formation || guanosine-containing compound metabolic process || receptor clustering || ribonucleoside biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || purine-containing compound biosynthetic process || ciliary receptor clustering involved in smoothened signaling pathway || nucleobase-containing compound metabolic process || purine nucleoside biosynthetic process || heterocycle biosynthetic process || phosphate-containing compound metabolic process || determination of bilateral symmetry || central nervous system development || determination of left/right symmetry || nucleoside diphosphate metabolic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound metabolic process || epithelial cilium movement || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || intraflagellar transport || cellular nitrogen compound metabolic process || nucleoside phosphate metabolic process || microtubule-based process || GTP biosynthetic process || carbohydrate derivative metabolic process || nucleoside triphosphate biosynthetic process || protein localization to membrane || regulation of epithelial cell proliferation || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside diphosphate phosphorylation || nucleobase-containing small molecule metabolic process || phosphorus metabolic process || nucleoside phosphate biosynthetic process || glycosyl compound biosynthetic process || negative regulation of cell death || regulation of programmed cell death || microtubule-based movement || specification of symmetry || integrin-mediated signaling pathway || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || cytoskeleton-dependent intracellular transport || organophosphate biosynthetic process || positive regulation of epithelial cell proliferation || organic cyclic compound biosynthetic process || heterocycle metabolic process || cellular component movement || small molecule metabolic process || purine ribonucleotide biosynthetic process || cilium movement || purine ribonucleoside biosynthetic process || regulation of apoptotic process || smoothened signaling pathway || brain development || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process
Biological Process (BP)	organonitrogen compound metabolic process	0.07683	0.699	--	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || purine-containing compound biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	primary metabolic process	0.0756	0.2976	--	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || nucleoside phosphate metabolic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || nucleobase-containing compound biosynthetic process
Biological Process (BP)	metabolic process	0.2032	0.2411	--	INHERITED FROM: GTP metabolic process || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || heterocycle metabolic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || organic cyclic compound metabolic process || nucleoside diphosphate phosphorylation || small molecule metabolic process || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || nucleoside phosphate metabolic process || phosphate-containing compound metabolic process || GTP biosynthetic process || carbohydrate derivative metabolic process
Biological Process (BP)	cellular metabolic process	0.1331	0.2708	--	INHERITED FROM: GTP metabolic process || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || heterocycle metabolic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || nucleoside phosphate metabolic process || phosphate-containing compound metabolic process || GTP biosynthetic process
Biological Process (BP)	organic substance metabolic process	0.2638	0.2676	--	INHERITED FROM: GTP metabolic process || nucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || organophosphate biosynthetic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || glycosyl compound metabolic process || purine ribonucleoside metabolic process || organic cyclic compound metabolic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || nucleoside phosphate metabolic process || GTP biosynthetic process || carbohydrate derivative metabolic process
Biological Process (BP)	cellular process	0.1432	0.1415	--	INHERITED FROM: GTP metabolic process || nucleoside triphosphate biosynthetic process || protein localization to membrane || nucleotide phosphorylation || guanosine-containing compound metabolic process || receptor clustering || ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || nucleobase-containing compound biosynthetic process || purine ribonucleoside metabolic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || nucleobase-containing small molecule metabolic process || ciliary receptor clustering involved in smoothened signaling pathway || nucleobase-containing compound metabolic process || phosphorus metabolic process || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || heterocycle biosynthetic process || phosphate-containing compound metabolic process || microtubule-based movement || integrin-mediated signaling pathway || cellular nitrogen compound biosynthetic process || nucleoside biosynthetic process || cytoskeleton-dependent intracellular transport || organophosphate biosynthetic process || nucleoside diphosphate metabolic process || purine ribonucleoside triphosphate biosynthetic process || heterocycle metabolic process || cellular component movement || epithelial cilium movement || purine ribonucleotide biosynthetic process || cilium movement || purine ribonucleoside biosynthetic process || organophosphate metabolic process || purine nucleoside triphosphate biosynthetic process || intraflagellar transport || smoothened signaling pathway || cellular nitrogen compound metabolic process || cellular aromatic compound metabolic process || ribonucleoside triphosphate biosynthetic process || nucleoside phosphate metabolic process || microtubule-based process || GTP biosynthetic process
Biological Process (BP)	nucleotide metabolic process	1	1.222	--	INHERITED FROM: GTP metabolic process || GTP biosynthetic process || nucleotide phosphorylation || purine ribonucleotide biosynthetic process || nucleoside diphosphate phosphorylation
Biological Process (BP)	cellular component organization	1	0.6819	--	INHERITED FROM: receptor clustering || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || intraflagellar transport
Biological Process (BP)	protein localization	0.03875	1.222	--	INHERITED FROM: receptor clustering || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway
Biological Process (BP)	cellular protein localization	0.01183	1.337	--	INHERITED FROM: receptor clustering || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway
Biological Process (BP)	cellular macromolecule localization	0.01446	1.319	--	INHERITED FROM: receptor clustering || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway
Biological Process (BP)	regulation of cell death	0.001488	1.301	--	INHERITED FROM: regulation of programmed cell death || regulation of apoptotic process || negative regulation of cell death
Biological Process (BP)	transport	0.1193	0.7747	--	INHERITED FROM: cytoskeleton-dependent intracellular transport || intraflagellar transport
Biological Process (BP)	single-organism transport	0.06266	0.8013	--	INHERITED FROM: cytoskeleton-dependent intracellular transport || intraflagellar transport
Biological Process (BP)	intracellular transport	0.08149	1.194	--	INHERITED FROM: cytoskeleton-dependent intracellular transport || intraflagellar transport
Biological Process (BP)	establishment of localization	0.1381	0.7696	--	INHERITED FROM: cytoskeleton-dependent intracellular transport || intraflagellar transport
Biological Process (BP)	establishment of localization in cell	0.1988	1.119	--	INHERITED FROM: cytoskeleton-dependent intracellular transport || intraflagellar transport
Biological Process (BP)	cellular biosynthetic process	0.006172	0.5498	--	INHERITED FROM: heterocycle biosynthetic process || ribonucleoside triphosphate biosynthetic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || cellular nitrogen compound biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	single-multicellular organism process	0.3119	0.6383	--	INHERITED FROM: specification of symmetry || determination of bilateral symmetry || central nervous system development || determination of left/right symmetry || left/right pattern formation || brain development
Biological Process (BP)	multicellular organismal development	0.314	0.7496	--	INHERITED FROM: specification of symmetry || determination of bilateral symmetry || central nervous system development || determination of left/right symmetry || brain development || left/right pattern formation
Biological Process (BP)	ribonucleoside triphosphate metabolic process	1	2	--	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process
Biological Process (BP)	purine nucleoside triphosphate metabolic process	1	1.921	--	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine nucleoside triphosphate biosynthetic process
Biological Process (BP)	organic substance biosynthetic process	0.0209	0.5376	--	INHERITED FROM: ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || organophosphate biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	carbohydrate derivative biosynthetic process	0.01031	1.222	--	INHERITED FROM: nucleoside biosynthetic process || guanosine-containing compound biosynthetic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process || ribonucleoside biosynthetic process
Biological Process (BP)	nucleoside metabolic process	0.00803	1.444	--	INHERITED FROM: nucleoside biosynthetic process || guanosine-containing compound biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || ribonucleoside biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || purine nucleoside biosynthetic process
Biological Process (BP)	purine nucleotide biosynthetic process	0.001817	1.62	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	ribonucleotide biosynthetic process	0.02437	1.745	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	ribose phosphate biosynthetic process	0.007702	1.699	--	INHERITED FROM: purine ribonucleotide biosynthetic process || GTP biosynthetic process
Biological Process (BP)	system development	0.1384	0.8069	--	INHERITED FROM: central nervous system development || brain development
Biological Process (BP)	anatomical structure development	0.07442	0.7212	--	INHERITED FROM: central nervous system development || brain development
Biological Process (BP)	cell communication	0.01284	0.8477	--	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	signaling	0.006881	0.8416	--	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	single organism signaling	0.006876	0.8601	--	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	cellular response to stimulus	0.01782	0.7645	--	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	cell surface receptor signaling pathway	0.005812	1.237	--	INHERITED FROM: integrin-mediated signaling pathway || smoothened signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway
Biological Process (BP)	purine ribonucleotide metabolic process	0.5819	1.62	--	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	ribonucleotide metabolic process	0.8039	1.62	--	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	cellular aromatic compound metabolic process	0.0007282	0.6271	Least Informative	DIRECT
Biological Process (BP)	heterocycle metabolic process	0.0004978	0.6308	Least Informative	DIRECT
Biological Process (BP)	organic cyclic compound metabolic process	0.0009004	0.5817	Least Informative	DIRECT
Biological Process (BP)	nitrogen compound metabolic process	0.003077	0.5171	Least Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || cellular nitrogen compound biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleobase-containing compound metabolic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || cellular nitrogen compound metabolic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || nucleoside phosphate metabolic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || nucleobase-containing compound biosynthetic process
Biological Process (BP)	single-organism metabolic process	0.001253	0.5376	Least Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside metabolic process || nucleoside diphosphate phosphorylation || small molecule metabolic process || purine ribonucleotide biosynthetic process || nucleobase-containing small molecule metabolic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || nucleotide phosphorylation || purine nucleoside biosynthetic process || nucleoside phosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || nucleoside phosphate metabolic process || guanosine-containing compound metabolic process || nucleoside diphosphate metabolic process || ribonucleoside biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || glycosyl compound metabolic process
Biological Process (BP)	cellular component organization or biogenesis	0.05831	0.6536	Least Informative	INHERITED FROM: receptor clustering || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || intraflagellar transport
Biological Process (BP)	localization	0.2497	0.6946	Least Informative	INHERITED FROM: receptor clustering || cytoskeleton-dependent intracellular transport || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || intraflagellar transport
Biological Process (BP)	biosynthetic process	0.00583	0.52	Least Informative	INHERITED FROM: heterocycle biosynthetic process || ribonucleoside triphosphate biosynthetic process || glycosyl compound biosynthetic process || aromatic compound biosynthetic process || nucleoside diphosphate phosphorylation || purine-containing compound biosynthetic process || purine ribonucleotide biosynthetic process || ribonucleoside biosynthetic process || cellular nitrogen compound biosynthetic process || purine ribonucleoside triphosphate biosynthetic process || organic cyclic compound biosynthetic process || nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || nucleoside triphosphate biosynthetic process || purine nucleoside triphosphate biosynthetic process || guanosine-containing compound biosynthetic process || GTP biosynthetic process || organophosphate biosynthetic process || purine nucleoside biosynthetic process || nucleobase-containing compound biosynthetic process || nucleoside phosphate biosynthetic process
Biological Process (BP)	multicellular organismal process	0.1839	0.6091	Least Informative	INHERITED FROM: specification of symmetry || determination of bilateral symmetry || multicellular organismal reproductive process || central nervous system development || determination of left/right symmetry || left/right pattern formation || brain development
Biological Process (BP)	developmental process	0.1396	0.6904	Least Informative	INHERITED FROM: specification of symmetry || determination of bilateral symmetry || central nervous system development || determination of left/right symmetry || left/right pattern formation || brain development
Biological Process (BP)	response to stimulus	0.2509	0.5498	Least Informative	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	regulation of cellular process	0.02419	0.5317	Least Informative	INHERITED FROM: integrin-mediated signaling pathway || regulation of epithelial cell proliferation || positive regulation of epithelial cell proliferation || ciliary receptor clustering involved in smoothened signaling pathway || regulation of apoptotic process || smoothened signaling pathway || negative regulation of cell death || regulation of programmed cell death
Biological Process (BP)	single-organism cellular process	0.7426	0.3915	Least Informative	INHERITED FROM: integrin-mediated signaling pathway || cytoskeleton-dependent intracellular transport || protein localization to membrane || receptor clustering || cellular component movement || epithelial cilium movement || cilium movement || ciliary receptor clustering involved in smoothened signaling pathway || intraflagellar transport || smoothened signaling pathway || microtubule-based process || microtubule-based movement
Biological Process (BP)	phosphate-containing compound metabolic process	7.769e-05	0.8182	Moderately Informative	DIRECT
Biological Process (BP)	heterocycle biosynthetic process	6.723e-05	0.9355	Moderately Informative	DIRECT
Biological Process (BP)	aromatic compound biosynthetic process	6.134e-05	0.9747	Moderately Informative	DIRECT
Biological Process (BP)	organophosphate metabolic process	1.256e-07	0.9914	Moderately Informative	DIRECT
Biological Process (BP)	cellular nitrogen compound biosynthetic process	8.516e-05	0.9136	Moderately Informative	DIRECT
Biological Process (BP)	nucleobase-containing small molecule metabolic process	9.122e-12	1.086	Moderately Informative	DIRECT
Biological Process (BP)	carbohydrate derivative metabolic process	0.0004861	1.018	Moderately Informative	DIRECT
Biological Process (BP)	organic cyclic compound biosynthetic process	0.0001001	0.8928	Moderately Informative	DIRECT
Biological Process (BP)	macromolecule localization	0.14	1.046	Moderately Informative	INHERITED FROM: protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || receptor clustering
Biological Process (BP)	negative regulation of cellular process	0.3564	0.9355	Moderately Informative	INHERITED FROM: negative regulation of cell death
Biological Process (BP)	positive regulation of cellular process	0.312	0.9066	Moderately Informative	INHERITED FROM: positive regulation of epithelial cell proliferation
Biological Process (BP)	reproduction	0.0713	1.097	Moderately Informative	INHERITED FROM: multicellular organismal reproductive process
Biological Process (BP)	cellular localization	0.2919	1.027	Moderately Informative	INHERITED FROM: cytoskeleton-dependent intracellular transport || protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || intraflagellar transport || receptor clustering
Biological Process (BP)	organonitrogen compound biosynthetic process	0.06711	0.8861	Moderately Informative	INHERITED FROM: nucleoside biosynthetic process || purine ribonucleoside biosynthetic process || guanosine-containing compound biosynthetic process || purine-containing compound biosynthetic process || GTP biosynthetic process || purine ribonucleotide biosynthetic process || purine nucleoside biosynthetic process || ribonucleoside biosynthetic process
Biological Process (BP)	single-organism developmental process	0.06147	0.7645	Moderately Informative	INHERITED FROM: brain development
Biological Process (BP)	organ development	0.08641	0.9355	Moderately Informative	INHERITED FROM: brain development
Biological Process (BP)	nervous system development	0.0307	1.194	Moderately Informative	INHERITED FROM: central nervous system development || brain development
Biological Process (BP)	signal transduction	0.005373	0.9914	Moderately Informative	INHERITED FROM: integrin-mediated signaling pathway || ciliary receptor clustering involved in smoothened signaling pathway || smoothened signaling pathway
Biological Process (BP)	cellular component movement	0.0002554	1.398	Informative	DIRECT
Biological Process (BP)	microtubule-based process	2.6e-06	1.62	Informative	DIRECT
Biological Process (BP)	central nervous system development	0.000293	1.523	Informative	DIRECT
Biological Process (BP)	regulation of apoptotic process	5.663e-05	1.337	Informative	DIRECT
Biological Process (BP)	multicellular organismal reproductive process	0.0008032	1.337	Informative	DIRECT
Biological Process (BP)	negative regulation of cell death	0.0002335	1.699	Informative	DIRECT
Biological Process (BP)	purine-containing compound biosynthetic process	3.462e-05	1.523	Informative	DIRECT
Biological Process (BP)	glycosyl compound biosynthetic process	5.141e-05	1.585	Informative	DIRECT
Biological Process (BP)	purine nucleoside metabolic process	0.6725	1.553	Informative	INHERITED FROM: guanosine-containing compound biosynthetic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || guanosine-containing compound metabolic process || purine nucleoside biosynthetic process
Biological Process (BP)	ribonucleoside metabolic process	1	1.495	Informative	INHERITED FROM: guanosine-containing compound biosynthetic process || GTP metabolic process || purine ribonucleoside metabolic process || ribonucleoside biosynthetic process || guanosine-containing compound metabolic process || purine ribonucleoside biosynthetic process || GTP biosynthetic process
Biological Process (BP)	cellular membrane organization	0.001847	1.523	Informative	INHERITED FROM: protein localization to membrane || ciliary receptor clustering involved in smoothened signaling pathway || receptor clustering
Biological Process (BP)	regulation of cell proliferation	0.1167	1.42	Informative	INHERITED FROM: positive regulation of epithelial cell proliferation || regulation of epithelial cell proliferation
Biological Process (BP)	cell projection organization	0.001537	1.553	Informative	INHERITED FROM: intraflagellar transport
Biological Process (BP)	nucleoside triphosphate metabolic process	0.002439	1.745	Informative	INHERITED FROM: purine ribonucleoside triphosphate biosynthetic process || ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process || GTP metabolic process || purine nucleoside triphosphate biosynthetic process || nucleoside triphosphate biosynthetic process
Biological Process (BP)	purine nucleotide metabolic process	0.3497	1.553	Informative	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	ribose phosphate metabolic process	0.07101	1.585	Informative	INHERITED FROM: GTP biosynthetic process || GTP metabolic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	nucleotide biosynthetic process	0.002509	1.444	Informative	INHERITED FROM: nucleoside diphosphate phosphorylation || GTP biosynthetic process || purine ribonucleotide biosynthetic process
Biological Process (BP)	microtubule-based movement	7.463e-08	2.222	Highly Informative	DIRECT
Biological Process (BP)	nucleoside diphosphate metabolic process	4.368e-10	2.222	Highly Informative	DIRECT
Biological Process (BP)	nucleoside triphosphate biosynthetic process	1.639e-11	2.097	Highly Informative	DIRECT
Biological Process (BP)	positive regulation of epithelial cell proliferation	1.445e-06	2	Highly Informative	DIRECT
Biological Process (BP)	protein localization to membrane	8.393e-08	2.222	Highly Informative	DIRECT
Biological Process (BP)	guanosine-containing compound metabolic process	3.612e-06	2.097	Highly Informative	DIRECT
Biological Process (BP)	purine ribonucleoside triphosphate metabolic process	1	2	Highly Informative	INHERITED FROM: GTP metabolic process || purine ribonucleoside triphosphate biosynthetic process || GTP biosynthetic process
Biological Process (BP)	pattern specification process	0.00161	1.921	Highly Informative	INHERITED FROM: determination of left/right symmetry || specification of symmetry || left/right pattern formation || determination of bilateral symmetry
Molecular Function (MF)	nucleoside binding	1.064e-05	1.775	--	DIRECT
Molecular Function (MF)	purine nucleoside binding	1.03e-05	1.775	--	DIRECT
Molecular Function (MF)	nucleoside diphosphate kinase activity	0	2.679	--	DIRECT
Molecular Function (MF)	phosphotransferase activity, phosphate group as acceptor	0	2.377	--	DIRECT
Molecular Function (MF)	purine nucleotide binding	1.527e-05	1.679	--	DIRECT
Molecular Function (MF)	adenyl nucleotide binding	9.077e-07	1.833	--	DIRECT
Molecular Function (MF)	ribonucleoside binding	1.022e-05	1.775	--	DIRECT
Molecular Function (MF)	purine ribonucleoside binding	1.01e-05	1.775	--	DIRECT
Molecular Function (MF)	ribonucleotide binding	1.663e-05	1.599	--	DIRECT
Molecular Function (MF)	purine ribonucleotide binding	1.378e-05	1.679	--	DIRECT
Molecular Function (MF)	adenyl ribonucleotide binding	8.56e-07	1.833	--	DIRECT
Molecular Function (MF)	small molecule binding	0.0001945	1.317	--	DIRECT
Molecular Function (MF)	ion binding	0.0009748	0.8334	--	DIRECT
Molecular Function (MF)	nucleoside phosphate binding	9.82e-05	1.448	--	DIRECT
Molecular Function (MF)	catalytic activity	0.1079	0.2686	--	INHERITED FROM: phosphotransferase activity, phosphate group as acceptor || transferase activity || kinase activity || transferase activity, transferring phosphorus-containing groups || nucleoside diphosphate kinase activity || nucleobase-containing compound kinase activity
Molecular Function (MF)	purine ribonucleoside triphosphate binding	0.001435	1.775	--	INHERITED FROM: ATP binding
Molecular Function (MF)	molecular_function	1	0	--	INHERITED FROM: nucleoside binding || ribonucleoside binding || phosphotransferase activity, phosphate group as acceptor || ribonucleotide binding || adenyl nucleotide binding || transferase activity, transferring phosphorus-containing groups || purine ribonucleoside binding || adenyl ribonucleotide binding || nucleotide binding || small molecule binding || ATP binding || transferase activity || purine nucleotide binding || ion binding || purine nucleoside binding || kinase activity || purine ribonucleotide binding || nucleoside diphosphate kinase activity || nucleobase-containing compound kinase activity || nucleoside phosphate binding
Molecular Function (MF)	transferase activity	1.467e-07	0.7491	Least Informative	DIRECT
Molecular Function (MF)	binding	0.5809	0.3952	Least Informative	INHERITED FROM: purine ribonucleoside binding || purine ribonucleotide binding || purine nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ribonucleoside binding || ion binding || nucleoside phosphate binding || adenyl nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || small molecule binding || ATP binding
Molecular Function (MF)	transferase activity, transferring phosphorus-containing groups	7.403e-12	1.134	Moderately Informative	DIRECT
Molecular Function (MF)	organic cyclic compound binding	0.1637	0.846	Moderately Informative	INHERITED FROM: purine ribonucleoside binding || ribonucleoside binding || purine nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || nucleoside phosphate binding || adenyl nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ATP binding || purine ribonucleotide binding
Molecular Function (MF)	heterocyclic compound binding	0.1517	0.8932	Moderately Informative	INHERITED FROM: purine ribonucleoside binding || ribonucleoside binding || purine nucleotide binding || purine nucleoside binding || ribonucleotide binding || nucleotide binding || nucleoside phosphate binding || adenyl nucleotide binding || nucleoside binding || adenyl ribonucleotide binding || ATP binding || purine ribonucleotide binding
Molecular Function (MF)	anion binding	0.07536	1.076	Moderately Informative	INHERITED FROM: ATP binding
Molecular Function (MF)	nucleotide binding	9.82e-05	1.448	Informative	DIRECT
Molecular Function (MF)	kinase activity	3.487e-13	1.474	Informative	DIRECT
Molecular Function (MF)	ATP binding	4.93e-07	1.98	Highly Informative	DIRECT
Molecular Function (MF)	nucleobase-containing compound kinase activity	0	2.201	Highly Informative	DIRECT
Cellular Component (CC)	mitochondrion	7.35e-14	0.7422	--	DIRECT
Cellular Component (CC)	cell-substrate adherens junction	4.804e-09	2.241	--	DIRECT
Cellular Component (CC)	anchoring junction	1.723e-06	2.064	--	DIRECT
Cellular Component (CC)	cellular_component	0.016	0	--	INHERITED FROM: mitochondrion || cell-substrate junction || focal adhesion || lamellipodium || cell leading edge || ruffle || adherens junction || anchoring junction || cell-substrate adherens junction
Cellular Component (CC)	cell	0.001026	0.08068	--	INHERITED FROM: mitochondrion || lamellipodium || cell leading edge || ruffle
Cellular Component (CC)	cell part	0.001014	0.08068	--	INHERITED FROM: mitochondrion || lamellipodium || cell leading edge || ruffle
Cellular Component (CC)	intracellular	0.006349	0.1266	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	cytoplasm	0.00694	0.2515	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	organelle	0.006728	0.1836	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	membrane-bounded organelle	0.3325	0.2912	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular organelle	0.9381	0.1875	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular part	0.005013	0.1266	--	INHERITED FROM: mitochondrion
Cellular Component (CC)	intracellular membrane-bounded organelle	0.3216	0.2961	Least Informative	INHERITED FROM: mitochondrion
Cellular Component (CC)	cytoplasmic part	0.1588	0.2605	Least Informative	INHERITED FROM: mitochondrion
Cellular Component (CC)	cell projection	0.001775	1.079	Moderately Informative	INHERITED FROM: ruffle || lamellipodium
Cellular Component (CC)	cell leading edge	1.685e-07	1.638	Informative	DIRECT
Cellular Component (CC)	cell junction	0.001279	1.5	Informative	INHERITED FROM: cell-substrate adherens junction || adherens junction || cell-substrate junction || focal adhesion || anchoring junction
Cellular Component (CC)	ruffle	4.338e-09	2.241	Highly Informative	DIRECT
Cellular Component (CC)	adherens junction	1.221e-06	2.064	Highly Informative	DIRECT
Cellular Component (CC)	lamellipodium	2.742e-08	1.763	Highly Informative	DIRECT
Cellular Component (CC)	cell-substrate junction	1.315e-08	2.241	Highly Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Nucleoside-diphosphate kinase	0	2.56	--	DIRECT
Enzyme Commission (EC)	Transferring phosphorous-containing groups	0	0.2175	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0	--	DIRECT
Enzyme Commission (EC)	Phosphotransferases with a phosphate group as acce	0	1.281	Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	embryonic lethal	0	0.04414	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.007361	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.0009133	--	DIRECT
Worm Phenotype (WP)	physiology variant	0	0.01015	--	DIRECT
Worm Phenotype (WP)	morphology variant	0	0.06908	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.002746	--	DIRECT
Worm Phenotype (WP)	organism morphology variant	0	0.2034	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04212	--	DIRECT

Highlighted in gray are those with FDR_all>0.001

	XA term	FDR (all)	IC level	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	trunk region	0	0.1399	--	DIRECT
Xenopus ANatomical entity (XAN)	urogenital system	0	0.2252	--	DIRECT
Xenopus ANatomical entity (XAN)	genital system	0	0.264	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical group	0	0.01024	--	DIRECT
Xenopus ANatomical entity (XAN)	organism subdivision	0	0.01593	--	DIRECT
Xenopus ANatomical entity (XAN)	trunk	0	0.1399	--	DIRECT
Xenopus ANatomical entity (XAN)	compound organ	0	0.04453	--	DIRECT
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	0.06222	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical region	0	0.02266	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical structure	1	0	--	INHERITED FROM: trunk region || genital system || anatomical group || cavitated compound organ || compound organ || anatomical region || trunk || organism subdivision || gonad || urogenital system
Xenopus ANatomical entity (XAN)	anatomical system	1	0.1237	--	INHERITED FROM: genital system || urogenital system
Xenopus ANatomical entity (XAN)	whole organism	1	0	--	INHERITED FROM: trunk region || genital system || anatomical group || cavitated compound organ || compound organ || anatomical region || trunk || organism subdivision || gonad || urogenital system
Xenopus ANatomical entity (XAN)	gonad	0	0.3817	Least Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	whole plant	0	0.2738	--	DIRECT
Plant ANatomical entity (PAN)	cauline leaf	0	0.5959	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence meristem	0	0.6769	--	DIRECT
Plant ANatomical entity (PAN)	phyllome	0	0.2226	--	DIRECT
Plant ANatomical entity (PAN)	leaf lamina base	0	0.6084	--	DIRECT
Plant ANatomical entity (PAN)	shoot system	0	0.07669	--	DIRECT
Plant ANatomical entity (PAN)	portion of plant tissue	0	0.3703	--	DIRECT
Plant ANatomical entity (PAN)	plant organ	0	0.1026	--	DIRECT
Plant ANatomical entity (PAN)	sporophyll	0	0.3284	--	DIRECT
Plant ANatomical entity (PAN)	stamen	0	0.5172	--	DIRECT
Plant ANatomical entity (PAN)	carpel	0	0.507	--	DIRECT
Plant ANatomical entity (PAN)	flower	0	0.2797	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence	0	0.4686	--	DIRECT
Plant ANatomical entity (PAN)	perianth	0	0.4291	--	DIRECT
Plant ANatomical entity (PAN)	corolla	0	0.502	--	DIRECT
Plant ANatomical entity (PAN)	calyx	0	0.444	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence branch	0	0.5095	--	DIRECT
Plant ANatomical entity (PAN)	cotyledon	0	0.6732	--	DIRECT
Plant ANatomical entity (PAN)	petiole	0	0.6245	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence axis	0	0.5095	--	DIRECT
Plant ANatomical entity (PAN)	leaf apex	0	0.6147	--	DIRECT
Plant ANatomical entity (PAN)	stem internode	0	0.5464	--	DIRECT
Plant ANatomical entity (PAN)	cardinal organ part	0	0.4027	--	DIRECT
Plant ANatomical entity (PAN)	plant axis	0	0.2426	--	DIRECT
Plant ANatomical entity (PAN)	collective phyllome structure	0	0.3251	--	DIRECT
Plant ANatomical entity (PAN)	root system	0	0.4229	--	DIRECT
Plant ANatomical entity (PAN)	shoot axis	0	0.3301	--	DIRECT
Plant ANatomical entity (PAN)	leaf	0	0.3852	--	DIRECT
Plant ANatomical entity (PAN)	lamina	0	0.6052	--	DIRECT
Plant ANatomical entity (PAN)	reproductive shoot system	0	0.2622	--	DIRECT
Plant ANatomical entity (PAN)	microsporangium	0	0.6345	--	DIRECT
Plant ANatomical entity (PAN)	pollen sac	0	0.6447	--	DIRECT
Plant ANatomical entity (PAN)	pollen	0	0.6447	--	DIRECT
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	0.08516	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.02574	--	DIRECT
Plant ANatomical entity (PAN)	cardinal part of multi-tissue plant structure	0	0.4007	--	DIRECT
Plant ANatomical entity (PAN)	stomatal complex	8.438e-05	0.9669	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermal cell	8.592e-05	0.9527	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermis	0.0001353	0.9255	--	DIRECT
Plant ANatomical entity (PAN)	epidermis	0.001108	0.853	--	INHERITED FROM: shoot epidermis || shoot epidermal cell || stomatal complex || guard cell
Plant ANatomical entity (PAN)	epidermal cell	0.004566	0.8818	--	INHERITED FROM: shoot epidermal cell || guard cell
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: lamina || leaf lamina || androecium || inflorescence || vascular leaf || petiole || phyllome || shoot system || inflorescence meristem || microsporangium || portion of meristem tissue || perianth || plant axis || root || reproductive shoot system || plant cell || stamen || shoot internode || shoot apex || leaf apex || cardinal organ part || shoot epidermal cell || carpel || collective leaf structure || plant embryo || multi-tissue plant structure || inflorescence branch || stem || guard cell || calyx || microgametophyte || collective phyllome structure || inflorescence axis || seed || flower || shoot axis || cauline leaf || leaf || petal || shoot epidermis || phyllome apex || sporophyll || portion of plant tissue || sporangium || whole plant || corolla || pedicel || megasporophyll || pollen sac || collective plant structure || microsporophyll || cardinal part of multi-tissue plant structure || stalk || stem internode || cotyledon || root system || pollen || plant organ || sepal || gynoecium || stomatal complex || leaf lamina base
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.05844	--	INHERITED FROM: calyx || collective phyllome structure || inflorescence axis || leaf lamina || androecium || flower || shoot axis || cauline leaf || inflorescence || leaf || vascular leaf || petal || petiole || phyllome || shoot epidermis || phyllome apex || shoot system || sporophyll || corolla || inflorescence meristem || pedicel || megasporophyll || pollen sac || microsporophyll || perianth || root || reproductive shoot system || stem internode || stamen || shoot internode || shoot apex || cotyledon || leaf apex || root system || pollen || shoot epidermal cell || carpel || sepal || collective leaf structure || gynoecium || stomatal complex || leaf lamina base || inflorescence branch || stem || guard cell
Plant ANatomical entity (PAN)	phyllome lamina	1	0.6052	--	INHERITED FROM: leaf lamina base || leaf lamina
Plant ANatomical entity (PAN)	organ lamina	1	0.6052	--	INHERITED FROM: leaf lamina base || leaf lamina
Plant ANatomical entity (PAN)	shoot apex	0	0.4333	Least Informative	DIRECT
Plant ANatomical entity (PAN)	shoot internode	0	0.5437	Least Informative	DIRECT
Plant ANatomical entity (PAN)	plant cell	0	0.5989	Least Informative	DIRECT
Plant ANatomical entity (PAN)	root	0	0.4462	Least Informative	DIRECT
Plant ANatomical entity (PAN)	plant embryo	0	0.4686	Least Informative	DIRECT
Plant ANatomical entity (PAN)	seed	0	0.4756	Least Informative	DIRECT
Plant ANatomical entity (PAN)	portion of meristem tissue	0	0.5837	Least Informative	DIRECT
Plant ANatomical entity (PAN)	vascular leaf	0	0.4066	Least Informative	DIRECT
Plant ANatomical entity (PAN)	megasporophyll	0	0.507	Least Informative	DIRECT
Plant ANatomical entity (PAN)	microsporophyll	0	0.3796	Least Informative	DIRECT
Plant ANatomical entity (PAN)	sepal	0	0.444	Least Informative	DIRECT
Plant ANatomical entity (PAN)	petal	0	0.502	Least Informative	DIRECT
Plant ANatomical entity (PAN)	stem	0	0.464	Least Informative	DIRECT
Plant ANatomical entity (PAN)	pedicel	0	0.5095	Least Informative	DIRECT
Plant ANatomical entity (PAN)	androecium	0	0.5095	Least Informative	DIRECT
Plant ANatomical entity (PAN)	gynoecium	0	0.502	Least Informative	DIRECT
Plant ANatomical entity (PAN)	leaf lamina	0	0.6052	Least Informative	DIRECT
Plant ANatomical entity (PAN)	collective leaf structure	0	0.4187	Least Informative	DIRECT
Plant ANatomical entity (PAN)	stalk	0	0.6021	Least Informative	DIRECT
Plant ANatomical entity (PAN)	sporangium	0	0.6311	Least Informative	DIRECT
Plant ANatomical entity (PAN)	phyllome apex	0	0.6084	Least Informative	DIRECT
Plant ANatomical entity (PAN)	microgametophyte	0	0.6447	Least Informative	DIRECT
Plant ANatomical entity (PAN)	guard cell	7.876e-05	0.9742	Moderately Informative	DIRECT
Plant structure DEvelopment stage (PDE)	leaf development stage	0	0.472	--	DIRECT
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	0.1933	--	DIRECT
Plant structure DEvelopment stage (PDE)	1 main shoot growth stage	0	0.3902	--	DIRECT
Plant structure DEvelopment stage (PDE)	leaf production stage	0	0.3902	--	DIRECT
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	0.2002	--	DIRECT
Plant structure DEvelopment stage (PDE)	3 flower organ development stage	0	0.09024	--	DIRECT
Plant structure DEvelopment stage (PDE)	corolla development stage	0	0.1947	--	DIRECT
Plant structure DEvelopment stage (PDE)	4 anthesis stage	0	0.2141	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	0.2799	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	0.04663	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	0.4694	--	DIRECT
Plant structure DEvelopment stage (PDE)	flower development stage	1	0.06738	--	INHERITED FROM: corolla development stage || 4 anthesis stage || 3 flower organ development stage
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	0.1988	--	INHERITED FROM: 1 main shoot growth stage || LP.02 two leaves visible stage || E expanded cotyledon stage || LP.10 ten leaves visible stage || LP.08 eight leaves visible stage || leaf production stage || LP.06 six leaves visible stage || LP.12 twelve leaves visible stage || LP.04 four leaves visible stage || F mature embryo stage || D bilateral stage || C globular stage || sporophyte vegetative stage || plant embryo stage
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	0.06738	--	INHERITED FROM: corolla development stage || 4 anthesis stage || 3 flower organ development stage
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	1	0.06738	--	INHERITED FROM: corolla development stage || 4 anthesis stage || 3 flower organ development stage
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	0.1988	--	INHERITED FROM: LP.06 six leaves visible stage || LP.12 twelve leaves visible stage || 1 main shoot growth stage || LP.04 four leaves visible stage || F mature embryo stage || D bilateral stage || LP.02 two leaves visible stage || E expanded cotyledon stage || LP.10 ten leaves visible stage || C globular stage || sporophyte vegetative stage || LP.08 eight leaves visible stage || plant embryo stage || leaf production stage
Plant structure DEvelopment stage (PDE)	4 leaf senescence stage	0	0.4745	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	E expanded cotyledon stage	0	0.3496	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	F mature embryo stage	0	0.4054	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	C globular stage	0	0.3902	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	D bilateral stage	0	0.3735	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.12 twelve leaves visible stage	0	0.5631	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.08 eight leaves visible stage	0	0.5826	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.02 two leaves visible stage	0	0.56	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.10 ten leaves visible stage	0	0.5095	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.04 four leaves visible stage	0	0.4303	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.06 six leaves visible stage	0	0.5209	Least Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Transferases	0	0.32	--	DIRECT
Enzyme Commission (EC)	Nucleoside-diphosphate kinase	0	2.926	--	DIRECT
Enzyme Commission (EC)	Transferring phosphorous-containing groups	0	0.5284	Least Informative	DIRECT
Enzyme Commission (EC)	Phosphotransferases with a phosphate group as acceptor	0	1.604	Informative	DIRECT

Highlighted in gray are those with FDR_all>0.001

	KW term	FDR (all)	IC level	SDKW level	Annotation (direct or inherited)
Biological process	Differentiation	0.005407	1.112	Moderately Informative	INHERITED FROM: Spermatogenesis
Biological process	Nucleotide metabolism	0	2.094	Highly Informative	DIRECT
Biological process	Spermatogenesis	0.0009723	1.793	Highly Informative	DIRECT
Cellular component	Cytoplasm	0	0.5208	Least Informative	DIRECT
Molecular function	ATP-binding	0	0.7016	--	DIRECT
Molecular function	Metal-binding	0	0.3713	Least Informative	DIRECT
Molecular function	Nucleotide-binding	0	0.6016	Least Informative	DIRECT
Molecular function	Magnesium	0	0.8908	Moderately Informative	DIRECT
Post-translational modification	Transferase	0	0.5454	Least Informative	DIRECT
Post-translational modification	Kinase	0	1.033	Moderately Informative	DIRECT
Post-translational modification	Phosphoprotein	0	0.4014	Least Informative	DIRECT