SUPERFAMILY 1.75 HMM library and genome assignments server


DNA-binding domain of Mlu1-box binding protein MBP1 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54615]
Superfamily:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54616]
Families:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54617]


Superfamily statistics
Genomes (239) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 1,912 1,352 3
Proteins 1,907 1,348 3


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 3.591e-08 Least Informative Direct
Biological Process (BP) single-organism cellular process 1.009e-05 Least Informative Direct
Biological Process (BP) regulation of cellular process 1.826e-05 Least Informative Direct
Biological Process (BP) reproduction 0.0002729 Moderately Informative Direct
Biological Process (BP) regulation of biosynthetic process 1.515e-10 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 2.722e-10 Moderately Informative Direct
Biological Process (BP) regulation of cellular metabolic process 6.579e-09 Moderately Informative Direct
Biological Process (BP) regulation of nitrogen compound metabolic process 2.443e-10 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.02093 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.05788 Moderately Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 2.076e-15 Informative Direct
Biological Process (BP) cell cycle process 2.809e-11 Informative Direct
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.04957 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.02629 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.07366 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.03784 Informative Inherited
Biological Process (BP) mitotic cell cycle 1.34e-05 Highly Informative Direct
Biological Process (BP) cell cycle phase 6.648e-09 Highly Informative Direct
Biological Process (BP) cell cycle phase transition 8.626e-10 Highly Informative Direct
Molecular Function (MF) binding 0.003659 Least Informative Inherited
Molecular Function (MF) organic cyclic compound binding 2.625e-06 Moderately Informative Direct
Molecular Function (MF) heterocyclic compound binding 2.176e-06 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding transcription factor activity 3.24e-07 Informative Direct
Molecular Function (MF) DNA binding 1.001e-10 Informative Direct
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 2.976e-07 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.003789 Least Informative Inherited
Cellular Component (CC) protein complex 0.01417 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.009899 Least Informative Inherited
Cellular Component (CC) nuclear part 0.002147 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.003874 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.02181 Informative Inherited
Cellular Component (CC) transcription factor complex 3.717e-08 Highly Informative Direct

Document: GO annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)development0InformativeDirect

Document: YP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation2.977e-11Moderately InformativeDirect
Cellular componentNucleus5.179e-11Least InformativeDirect
DomainRepeat6.413e-05Least InformativeDirect
DomainANK repeat2.339e-14InformativeDirect
Molecular functionDNA-binding4.612e-16Moderately InformativeDirect
Post-translational modificationPhosphoprotein4.275e-05Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DNA-binding domain of Mlu1-box binding protein MBP1 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the DNA-binding domain of Mlu1-box binding protein MBP1 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) · Internal database links ]