SUPERFAMILY 1.75 HMM library and genome assignments server


DNA-binding domain of Mlu1-box binding protein MBP1 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54615]
Superfamily:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54616]
Families:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54617]


Superfamily statistics
Genomes (262) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,920 2,148 3
Proteins 1,915 2,142 3


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.0002342 Least Informative Direct
Biological Process (BP) developmental process 0.8623 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.00911 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.02568 Least Informative Inherited
Biological Process (BP) regulation of biosynthetic process 3.99e-07 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 6.64e-07 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 6.305e-07 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.08956 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.116 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.01013 Moderately Informative Inherited
Biological Process (BP) mitotic cell cycle 0.000999 Informative Direct
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 5.06e-12 Informative Direct
Biological Process (BP) cell cycle process 6.402e-10 Informative Direct
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.1306 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.07955 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.1821 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.09569 Informative Inherited
Biological Process (BP) mitotic cell cycle phase transition 0 Highly Informative Direct
Biological Process (BP) interphase 0 Highly Informative Direct
Biological Process (BP) positive regulation of transcription, DNA-dependent 0.2076 Highly Informative Inherited
Molecular Function (MF) binding 0.9737 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.03526 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 7.988e-07 Informative Direct
Molecular Function (MF) DNA binding 0.0062 Informative Inherited
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 7.739e-07 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.2152 Least Informative Inherited
Cellular Component (CC) protein complex 0.2617 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.1692 Least Informative Inherited
Cellular Component (CC) nuclear part 0.01346 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.006516 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.02079 Informative Inherited
Cellular Component (CC) transcription factor complex 1.639e-06 Highly Informative Direct

Document: GO annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation2.568e-12Moderately InformativeDirect
Cellular componentNucleus5.906e-12Least InformativeDirect
DomainRepeat0.0001236Least InformativeDirect
DomainANK repeat4.309e-14InformativeDirect
Molecular functionDNA-binding0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0006316Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DNA-binding domain of Mlu1-box binding protein MBP1 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the DNA-binding domain of Mlu1-box binding protein MBP1 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) · Internal database links ]