SUPERFAMILY 1.75 HMM library and genome assignments server


DNA-binding domain of Mlu1-box binding protein MBP1 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54615]
Superfamily:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54616]
Families:   DNA-binding domain of Mlu1-box binding protein MBP1 [ 54617]


Superfamily statistics
Genomes (262) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,920 2,148 3
Proteins 1,915 2,142 3


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.0002243 Least Informative Direct
Biological Process (BP) developmental process 0.668 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.001079 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.002681 Least Informative Inherited
Biological Process (BP) regulation of gene expression 3.912e-08 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 8.14e-09 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 3.656e-08 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 1.74e-08 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.09208 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.1194 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.07511 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.003992 Moderately Informative Inherited
Biological Process (BP) mitotic cell cycle 0.0009938 Informative Direct
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 2.002e-13 Informative Direct
Biological Process (BP) cell cycle process 5.695e-10 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.0008827 Informative Direct
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.1318 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.08161 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.1839 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.09666 Informative Inherited
Biological Process (BP) cell cycle phase 8.2e-12 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0 Highly Informative Direct
Biological Process (BP) positive regulation of transcription, DNA-dependent 0.2114 Highly Informative Inherited
Molecular Function (MF) binding 0.7707 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.01706 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 3.203e-11 Informative Direct
Molecular Function (MF) DNA binding 0.002812 Informative Inherited
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 3.073e-11 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.06235 Least Informative Inherited
Cellular Component (CC) protein complex 0.1511 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.0698 Least Informative Inherited
Cellular Component (CC) nuclear part 0.01258 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.003479 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.02187 Informative Inherited

Document: GO annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation2.582e-12Moderately InformativeDirect
Cellular componentNucleus5.804e-12Least InformativeDirect
DomainRepeat0.0001235Least InformativeDirect
DomainANK repeat4.29e-14InformativeDirect
Molecular functionDNA-binding0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0006341Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DNA-binding domain of Mlu1-box binding protein MBP1 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the DNA-binding domain of Mlu1-box binding protein MBP1 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Yeast Phenotype (YP) · UniProtKB KeyWords (KW) · Internal database links ]