SUPERFAMILY 1.75 HMM library and genome assignments server

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Pili subunits superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Pili subunits [ 54522]
Superfamily:   Pili subunits [ 54523] (7)
Families:   Pilin [ 54524] (4)
  TcpA-like pilin [ 89868]
  Pseudopilin [ 117865]
  YadA C-terminal domain-like [ 143107]
  EpsJ-like [ 160127] (2)
  GspK pilin-like domain [ 160132]
  GSPII I/J protein-like [ 160135] (2)


Superfamily statistics
Genomes (1,771) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 10,633 70,779 15
Proteins 10,530 70,026 15


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.00000032080.0001014Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.000000020480.0003355Least InformativeDirect
Biological Process (BP)localization0.036240.02773Least InformativeInherited
Biological Process (BP)multi-organism process0.00095440.00002498Moderately InformativeDirect
Biological Process (BP)cellular localization0.14440.006471Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.12020.1075Moderately InformativeInherited
Biological Process (BP)organic substance transport0.002510.000008297Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.0049460.00009345Moderately InformativeInherited
Biological Process (BP)protein transport0.000016290.000000005667InformativeDirect
Biological Process (BP)cell projection organization00.0000000000001736InformativeDirect
Biological Process (BP)secretion by cell0.000024640.000000001098InformativeDirect
Biological Process (BP)transmembrane transport0.053460.003512InformativeInherited
Biological Process (BP)pathogenesis0.00005880.000000001216Highly InformativeDirect
Biological Process (BP)cell projection assembly0.00000022170.0000005143Highly InformativeDirect
Molecular Function (MF)structural molecule activity0.0000000022020.0000000003071Moderately InformativeDirect
Cellular Component (CC)cell projection0.0000000000034110.0000000002338Moderately InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.0001014 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.0003355 Least Informative Direct
Biological Process (BP) localization 0.02773 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.00009345 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.00002498 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.000008297 Moderately Informative Direct
Biological Process (BP) cellular localization 0.006471 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.1075 Moderately Informative Inherited
Biological Process (BP) protein transport 0.000000005667 Informative Direct
Biological Process (BP) cell projection organization 0.0000000000001736 Informative Direct
Biological Process (BP) secretion by cell 0.000000001098 Informative Direct
Biological Process (BP) transmembrane transport 0.003512 Informative Inherited
Biological Process (BP) pathogenesis 0.000000001216 Highly Informative Direct
Biological Process (BP) cell projection assembly 0.0000005143 Highly Informative Direct
Molecular Function (MF) structural molecule activity 0.0000000003071 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0000000002338 Moderately Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processCell adhesion0.0000000000001352InformativeDirect
Biological processVirulence0.000005197InformativeDirect
Cellular componentMembrane0.1561Least InformativeInherited
Cellular componentCell outer membrane0.0000000002653InformativeDirect
DomainTransmembrane0.004559Least InformativeInherited
DomainTransmembrane beta strand0.0000005643InformativeDirect
Post-translational modificationMethylation0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 12 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Pili subunits domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 12 hidden Markov models representing the Pili subunits superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]