SUPERFAMILY 1.75 HMM library and genome assignments server

Pili subunits superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Pili subunits [ 54522]
Superfamily:   Pili subunits [ 54523] (7)
Families:   Pilin [ 54524] (4)
  TcpA-like pilin [ 89868]
  Pseudopilin [ 117865]
  YadA C-terminal domain-like [ 143107]
  EpsJ-like [ 160127] (2)
  GspK pilin-like domain [ 160132]
  GSPII I/J protein-like [ 160135] (2)


Superfamily statistics
Genomes (1,771) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 10,633 70,779 15
Proteins 10,530 70,026 15


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis0.000000023070.0004546Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0004030.005878Least InformativeInherited
Biological Process (BP)localization0.043230.03271Least InformativeInherited
Biological Process (BP)organic substance transport0.0025750.000008576Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.0040430.00006578Moderately InformativeInherited
Biological Process (BP)cellular localization0.020010.001559Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.11130.09577Moderately InformativeInherited
Biological Process (BP)multi-organism process0.0035670.0008996Moderately InformativeInherited
Biological Process (BP)protein transport0.000016420.000000005901InformativeDirect
Biological Process (BP)cell projection organization00.000000000000001913InformativeDirect
Biological Process (BP)secretion by cell0.0000026950.00000000009452InformativeDirect
Biological Process (BP)pathogenesis0.000016490.00000000002264Highly InformativeDirect
Biological Process (BP)cell projection assembly0.0000002050.0000004517Highly InformativeDirect
Molecular Function (MF)structural molecule activity0.0000000021750.000000000301Moderately InformativeDirect
Cellular Component (CC)cell projection0.000000000004330.0000000003392Moderately InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.0004546 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.005878 Least Informative Inherited
Biological Process (BP) localization 0.03271 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.00006578 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.0008996 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.000008576 Moderately Informative Direct
Biological Process (BP) cellular localization 0.001559 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.09577 Moderately Informative Inherited
Biological Process (BP) protein transport 0.000000005901 Informative Direct
Biological Process (BP) cell projection organization 0.000000000000001913 Informative Direct
Biological Process (BP) secretion by cell 0.00000000009452 Informative Direct
Biological Process (BP) pathogenesis 0.00000000002264 Highly Informative Direct
Biological Process (BP) cell projection assembly 0.0000004517 Highly Informative Direct
Molecular Function (MF) structural molecule activity 0.000000000301 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0000000003392 Moderately Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processCell adhesion0.0000000000001352InformativeDirect
Biological processVirulence0.000005197InformativeDirect
Cellular componentMembrane0.1561Least InformativeInherited
Cellular componentCell outer membrane0.0000000002653InformativeDirect
DomainTransmembrane0.004559Least InformativeInherited
DomainTransmembrane beta strand0.0000005643InformativeDirect
Post-translational modificationMethylation0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 12 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Pili subunits domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 12 hidden Markov models representing the Pili subunits superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]