SUPERFAMILY 1.75 HMM library and genome assignments server


Amine oxidase N-terminal region superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cystatin-like [ 54402] (7)
Superfamily:   Amine oxidase N-terminal region [ 54416]
Families:   Amine oxidase N-terminal region [ 54417] (2)


Superfamily statistics
Genomes (437) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 2,723 3,405 40
Proteins 1,422 1,760 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 6.979e-05 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0007675 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.8877 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.001082 Least Informative Inherited
Biological Process (BP) oxidation-reduction process 4.008e-15 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 2.933e-10 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 1.526e-08 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0001311 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.06862 Moderately Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 4.008e-15 Informative Direct
Biological Process (BP) response to inorganic substance 4.685e-11 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 5.068e-11 Informative Direct
Biological Process (BP) response to organic cyclic compound 6.722e-08 Informative Direct
Biological Process (BP) response to organic nitrogen 5.07e-07 Informative Direct
Biological Process (BP) response to external stimulus 1.323e-06 Informative Direct
Biological Process (BP) biological adhesion 0.0002252 Informative Direct
Biological Process (BP) response to toxic substance 0 Highly Informative Direct
Biological Process (BP) cellular response to starvation 0 Highly Informative Direct
Biological Process (BP) response to drug 1.967e-11 Highly Informative Direct
Biological Process (BP) cellular response to organic cyclic compound 8.628e-11 Highly Informative Direct
Biological Process (BP) cellular response to metal ion 7.537e-06 Highly Informative Direct
Molecular Function (MF) binding 0.001427 Least Informative Inherited
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) transporter activity 3.063e-12 Moderately Informative Direct
Molecular Function (MF) protein binding 0.4688 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.1102 Moderately Informative Inherited
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) transition metal ion binding 0 Informative Direct
Molecular Function (MF) receptor activity 7.186e-12 Informative Direct
Molecular Function (MF) copper ion binding 0 Highly Informative Direct
Molecular Function (MF) protein complex binding 0 Highly Informative Direct
Molecular Function (MF) ion channel activity 0 Highly Informative Direct
Molecular Function (MF) drug binding 0 Highly Informative Direct
Molecular Function (MF) glycosaminoglycan binding 0 Highly Informative Direct
Molecular Function (MF) sulfur compound binding 0 Highly Informative Direct
Cellular Component (CC) membrane 0.0002608 Least Informative Direct
Cellular Component (CC) extracellular region 1.04e-09 Moderately Informative Direct
Cellular Component (CC) plasma membrane 2.319e-08 Moderately Informative Direct
Cellular Component (CC) extracellular space 0 Informative Direct
Cellular Component (CC) cell junction 8.868e-14 Informative Direct
Cellular Component (CC) cell surface 0.0003633 Informative Direct
Cellular Component (CC) cell-cell junction 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH(2) group of donors0InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion6.612e-09InformativeDirect
Cellular componentSecreted0.0005077Moderately InformativeDirect
DomainSignal1.2e-05Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainSignal-anchor4.614e-08Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionCopper0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationGlycoprotein0.000852Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Amine oxidase N-terminal region domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the Amine oxidase N-terminal region superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]