SUPERFAMILY 1.75 HMM library and genome assignments server

Amine oxidase N-terminal region superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cystatin-like [ 54402] (7)
Superfamily:   Amine oxidase N-terminal region [ 54416]
Families:   Amine oxidase N-terminal region [ 54417] (2)


Superfamily statistics
Genomes (522) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,146 6,849 40
Proteins 1,647 3,507 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.001314 Least Informative Inherited
Biological Process (BP) localization 0.006142 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.8847 Least Informative Inherited
Biological Process (BP) response to stimulus 0.01591 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.9832 Least Informative Inherited
Biological Process (BP) oxidation-reduction process 0 Moderately Informative Direct
Biological Process (BP) ion transport 0.0000000005808 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.000000001219 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 0.00000002722 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0001771 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.0004427 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.1002 Moderately Informative Inherited
Biological Process (BP) cellular response to external stimulus 0.000000000000003707 Informative Direct
Biological Process (BP) ion transmembrane transport 0.000000000000005526 Informative Direct
Biological Process (BP) response to nutrient levels 0.0000000000005269 Informative Direct
Biological Process (BP) response to inorganic substance 0.00000000002561 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 0.00000000009052 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.00000007798 Informative Direct
Biological Process (BP) response to organonitrogen compound 0.0000006285 Informative Direct
Biological Process (BP) biological adhesion 0.001049 Informative Inherited
Biological Process (BP) response to transition metal nanoparticle 0 Highly Informative Direct
Biological Process (BP) response to toxic substance 0 Highly Informative Direct
Biological Process (BP) response to drug 0.00000000001091 Highly Informative Direct
Biological Process (BP) cellular response to metal ion 0.00000389 Highly Informative Direct
Biological Process (BP) cell adhesion 0.0008617 Highly Informative Direct
Molecular Function (MF) binding 0.06671 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0000000000158 Moderately Informative Direct
Molecular Function (MF) transporter activity 0.0000000009178 Moderately Informative Direct
Molecular Function (MF) anion binding 0.2568 Moderately Informative Inherited
Molecular Function (MF) sulfur compound binding 0 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) protein complex binding 0.0000000000001619 Informative Direct
Molecular Function (MF) receptor activity 0.0000000006044 Informative Direct
Molecular Function (MF) copper ion binding 0 Highly Informative Direct
Molecular Function (MF) cation channel activity 0 Highly Informative Direct
Molecular Function (MF) heparin binding 0 Highly Informative Direct
Molecular Function (MF) drug binding 0 Highly Informative Direct
Cellular Component (CC) membrane 0.0457 Least Informative Inherited
Cellular Component (CC) extracellular region part 0.0000003235 Moderately Informative Direct
Cellular Component (CC) extracellular space 0.0000000000008695 Informative Direct
Cellular Component (CC) cell junction 0.0000000001732 Informative Direct
Cellular Component (CC) cell surface 0.00003827 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH(2) group of donors0InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0.000000004513InformativeDirect
Cellular componentSecreted0.0004942Moderately InformativeDirect
DomainSignal0.000005777Least InformativeDirect
DomainTransmembrane0.9262Least InformativeInherited
DomainSignal-anchor0.00000005042InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionCopper0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationGlycoprotein0.0007284Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Amine oxidase N-terminal region domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the Amine oxidase N-terminal region superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]