|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
autophagic vacuole assembly |
0.000137 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis |
0.0006913 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
neurotransmitter uptake |
1.083e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic development via the syncytial blastoderm |
0.0002124 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
formation of primary germ layer |
1.327e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
B cell homeostasis |
3.99e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
neural plate development |
1.416e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
synaptic transmission, dopaminergic |
2.774e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
startle response |
0.0001524 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte homeostasis |
7.812e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nucleotide metabolic process |
3.335e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
catecholamine metabolic process |
8.486e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
glycerophospholipid metabolic process |
4.098e-07 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
phosphatidylinositol biosynthetic process |
5.603e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cell communication |
7.031e-06 |
0.8477 |
-- |
DIRECT |
| Biological Process (BP) |
JNK cascade |
8.041e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization |
1.477e-06 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell death |
4.576e-06 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell shape |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
phospholipid biosynthetic process |
2.922e-08 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
catabolic process |
7.54e-08 |
0.7852 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule catabolic process |
0 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
catechol-containing compound metabolic process |
0.0003813 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
embryo development |
0.0001013 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catabolic process |
0 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catabolic process |
8.004e-08 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction |
9.166e-09 |
1.119 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
1.158e-14 |
0.1415 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell communication |
7.001e-06 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
dopamine transport |
9.753e-09 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
Wnt receptor signaling pathway |
1.005e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
macroautophagy |
3.054e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
death |
1.965e-07 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
phosphorylation |
2.877e-07 |
1.398 |
-- |
DIRECT |
| Biological Process (BP) |
protein sumoylation |
2.395e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transforming growth factor beta receptor signaling pathway |
0.0006241 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphate metabolic process |
2.484e-13 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
0 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of signaling |
2.415e-06 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of Wnt receptor signaling pathway |
1.743e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
ER-associated protein catabolic process |
5.199e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid elongation |
0.0001543 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transforming growth factor beta receptor signaling pathway |
0.0009459 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein ubiquitination |
3.474e-09 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
0 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular protein metabolic process |
0.0005255 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
1.268e-07 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
0.0003719 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription elongation from RNA polymerase II promoter |
0.0005803 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell junction organization |
0.0006519 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
establishment or maintenance of apical/basal cell polarity |
1.896e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
synaptic transmission, glutamatergic |
1.689e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
peptidyl-tyrosine dephosphorylation |
1.17e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to topologically incorrect protein |
2.227e-06 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
protein modification process |
1.046e-08 |
0.9066 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein catabolic process |
3.412e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
norepinephrine metabolic process |
4.853e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
dopamine metabolic process |
1.001e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of GTPase activity |
3.835e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
1.792e-07 |
0.4634 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein binding |
2.31e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of MAP kinase activity |
0.0009749 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule modification |
0 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of GTPase activity |
6.522e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of DNA-dependent transcription in response to stress |
2.343e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
modification-dependent macromolecule catabolic process |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of molecular function |
0.0003505 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein catabolic process |
0 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein metabolic process |
0 |
0.6778 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
4.785e-11 |
0.3316 |
-- |
DIRECT |
| Biological Process (BP) |
single organism signaling |
2.035e-09 |
0.8601 |
-- |
DIRECT |
| Biological Process (BP) |
glycerolipid biosynthetic process |
1.079e-12 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of proteolysis |
0.0004264 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of embryonic development |
0.0003845 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of JNK cascade |
1.928e-12 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of developmental growth |
5.68e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of skeletal muscle fiber development |
0.0006051 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catalytic activity |
1.782e-08 |
1.155 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of synaptic transmission |
0.0008545 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of binding |
1.049e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
6.564e-12 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
stress-activated MAPK cascade |
0.0008201 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
dopamine uptake involved in synaptic transmission |
3.727e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter transport |
0.000509 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
proteolysis involved in cellular protein catabolic process |
0 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
maintenance of location in cell |
3.618e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
catecholamine uptake involved in synaptic transmission |
3.727e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
catecholamine transport |
1.124e-07 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of synapse assembly |
0.0009345 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
membrane organization |
5.382e-05 |
1.523 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of proteasomal protein catabolic process |
3.33e-12 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
establishment or maintenance of bipolar cell polarity |
0.0006596 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
5.937e-08 |
0.4202 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological quality |
1.303e-05 |
0.8539 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress |
0.0001438 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
chromosome organization involved in meiosis |
0.0001224 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stress-activated protein kinase signaling cascade |
0.0001225 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellular macromolecule localization |
5.002e-06 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle arrest |
0.0001312 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to transforming growth factor beta stimulus |
0.0002139 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to transforming growth factor beta stimulus |
0.0002035 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway by p53 class mediator |
0.0005464 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
tubulin complex biogenesis |
1.723e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
catecholamine uptake |
3.727e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
dopamine uptake |
3.727e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of purine nucleotide metabolic process |
3.029e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of proteasomal protein catabolic process |
0.0005276 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
1.896e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc |
1.106e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein modification process |
0.3025 |
1.585 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of MAP kinase activity || positive regulation of protein ubiquitination |
| Biological Process (BP) |
regulation of protein modification process |
0.4832 |
1.377 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of protein ubiquitination || positive regulation of MAP kinase activity || regulation of protein ubiquitination || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0.851 |
1.301 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of protein ubiquitination || positive regulation of cellular protein metabolic process || positive regulation of MAP kinase activity || positive regulation of protein metabolic process |
| Biological Process (BP) |
protein modification by small protein conjugation |
0.07405 |
1.796 |
-- |
INHERITED FROM: protein linear polyubiquitination || protein autoubiquitination || protein sumoylation || protein ufmylation |
| Biological Process (BP) |
protein polyubiquitination |
0.2938 |
2.699 |
-- |
INHERITED FROM: protein linear polyubiquitination |
| Biological Process (BP) |
cation transport |
1 |
1.319 |
-- |
INHERITED FROM: dopamine uptake || dopamine transport || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
ear development |
0.8383 |
2.222 |
-- |
INHERITED FROM: cochlea morphogenesis || cochlea development |
| Biological Process (BP) |
ear morphogenesis |
0.007718 |
2.398 |
-- |
INHERITED FROM: cochlea morphogenesis |
| Biological Process (BP) |
inner ear morphogenesis |
0.2129 |
2.398 |
-- |
INHERITED FROM: cochlea morphogenesis |
| Biological Process (BP) |
cell part morphogenesis |
0.1929 |
1.796 |
-- |
INHERITED FROM: lamellipodium morphogenesis || axon extension |
| Biological Process (BP) |
cell projection morphogenesis |
0.8472 |
1.854 |
-- |
INHERITED FROM: lamellipodium morphogenesis || axon extension |
| Biological Process (BP) |
response to growth factor stimulus |
0.001233 |
2 |
-- |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || response to transforming growth factor beta stimulus |
| Biological Process (BP) |
cellular response to organic substance |
0.03824 |
1.208 |
-- |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || cellular response to topologically incorrect protein |
| Biological Process (BP) |
regulation of cell cycle |
1 |
1.444 |
-- |
INHERITED FROM: positive regulation of cell cycle arrest || regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of immune system process |
1 |
1.398 |
-- |
INHERITED FROM: nucleotide-binding oligomerization domain containing signaling pathway || TRIF-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
cell cycle |
1 |
1.377 |
-- |
INHERITED FROM: chromosome organization involved in meiosis || synaptonemal complex assembly || synapsis |
| Biological Process (BP) |
response to decreased oxygen levels |
0.1872 |
1.796 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
cellular response to decreased oxygen levels |
0.06985 |
2.398 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter in response to stress |
0.002534 |
2.699 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
response to oxygen levels |
0.2297 |
1.796 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
cellular response to oxygen levels |
0.0519 |
2.398 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
cellular response to hypoxia |
0.2037 |
2.398 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
regulation of primary metabolic process |
0.05058 |
0.7852 |
-- |
INHERITED FROM: regulation of proteasomal protein catabolic process || regulation of proteolysis || positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of protein metabolic process || regulation of transcription elongation from RNA polymerase II promoter || regulation of protein ubiquitination || positive regulation of protein metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || negative regulation of protein catabolic process || negative regulation of protein metabolic process || regulation of cellular protein metabolic process || negative regulation of proteasomal protein catabolic process || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of GTPase activity || regulation of protein catabolic process || negative regulation of DNA-dependent transcription, elongation || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || positive regulation of cellular protein metabolic process || positive regulation of MAP kinase activity || regulation of purine nucleotide metabolic process || negative regulation of proteolysis || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
1 |
0.7959 |
-- |
INHERITED FROM: regulation of proteasomal protein catabolic process || regulation of proteolysis || positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of protein metabolic process || regulation of transcription elongation from RNA polymerase II promoter || regulation of protein ubiquitination || positive regulation of protein metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || negative regulation of protein catabolic process || negative regulation of protein metabolic process || regulation of cellular protein metabolic process || negative regulation of proteasomal protein catabolic process || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of protein catabolic process || negative regulation of DNA-dependent transcription, elongation || positive regulation of cellular protein metabolic process || maintenance of DNA methylation || genetic imprinting || positive regulation of MAP kinase activity || regulation of protein stability || negative regulation of proteolysis || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation || dopamine uptake involved in synaptic transmission || cellular component organization or biogenesis || positive regulation of cell cycle arrest || embryonic morphogenesis || regulation of molecular function || peptidyl-tyrosine dephosphorylation || regulation of cell communication || toll-like receptor 4 signaling pathway || regulation of purine nucleotide metabolic process || protein modification process || positive regulation of cell size || response to transforming growth factor beta stimulus || negative regulation of Wnt receptor signaling pathway || negative regulation of nervous system development || molting cycle, collagen and cuticulin-based cuticle || catecholamine uptake involved in synaptic transmission || leukocyte migration || dopamine metabolic process || negative regulation of cellular catabolic process || regulation of phosphate metabolic process || cytoplasmic microtubule organization || regulation of cellular catabolic process || regulation of nucleoside metabolic process || chromosome organization involved in meiosis || maintenance of DNA methylation || positive regulation of MAP kinase activity || regulation of establishment or maintenance of cell polarity || MyD88-dependent toll-like receptor signaling pathway || JNK cascade || regulation of Wnt receptor signaling pathway || lipid modification || autophagic vacuole assembly || axon extension || positive regulation of type I interferon production || regulation of stress-activated protein kinase signaling cascade || toll-like receptor 5 signaling pathway || negative regulation of DNA-dependent transcription, elongation || cell junction organization || ectoderm development || regulation of proteasomal protein catabolic process || regulation of anatomical structure morphogenesis || nucleotide-binding oligomerization domain containing signaling pathway || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of cell shape || dopamine transport || convergent extension || regulation of protein ubiquitination || axial mesoderm development || glycerolipid metabolic process || macromolecule catabolic process || regulation of intracellular protein kinase cascade || protein insertion into ER membrane || collagen and cuticulin-based cuticle development || fatty acid elongation || cellular macromolecule catabolic process || membrane organization || cellular catabolic process || phospholipid metabolic process || catabolic process || neurotransmitter uptake || macromolecule modification || dorsal closure, elongation of leading edge cells || embryo development || post-anal tail morphogenesis || modification-dependent macromolecule catabolic process || phosphatidylinositol phosphorylation || developmental process || regulation of biological quality || neural plate morphogenesis || stress-activated protein kinase signaling cascade || proteolysis || protein metabolic process || regulation of signaling || regulation of catabolic process || regulation of establishment of planar polarity || regulation of cellular protein metabolic process || regulation of skeletal muscle fiber development || negative regulation of proteasomal protein catabolic process || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || toll-like receptor 3 signaling pathway || leukocyte homeostasis || catecholamine transport || organic substance catabolic process || protein linear polyubiquitination || stress-activated MAPK cascade || regulation of cellular process || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular response to transforming growth factor beta stimulus || actin filament-based process || initiation of dorsal closure || cellular macromolecule metabolic process || synapsis || lipid phosphorylation || dorsal/ventral axis specification || regulation of cell morphogenesis || regulation of GTPase activity || macroautophagy || positive regulation of cellular protein metabolic process || maintenance of location in cell || negative regulation of developmental growth || ER-associated protein catabolic process || positive regulation of phosphorus metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || negative regulation of protein catabolic process || positive regulation of molecular function || toll-like receptor 2 signaling pathway || proteolysis involved in cellular protein catabolic process || phosphatidylinositol-3-phosphate biosynthetic process || norepinephrine metabolic process || chaeta morphogenesis || protein localization || cochlea development || B cell homeostasis || neural plate development || synaptonemal complex assembly || negative regulation of cellular protein metabolic process || cellular macromolecule localization || synaptic transmission, glutamatergic || negative regulation of response to stimulus || catecholamine uptake || phospholipid biosynthetic process || cellular protein metabolic process || T cell receptor signaling pathway || tubulin complex biogenesis || ubiquitin homeostasis || negative regulation of catabolic process || protein polymerization || maintenance of location || cytoplasmic pattern recognition receptor signaling pathway || cellular membrane organization || negative regulation of cell-cell adhesion || protein modification by small protein conjugation or removal || ommatidial rotation || establishment or maintenance of bipolar cell polarity || protein ufmylation || intrinsic apoptotic signaling pathway in response to DNA damage || regulation of catenin import into nucleus || monoubiquitinated protein deubiquitination || signaling || modification-dependent protein catabolic process || regulation of protein stability || negative regulation of cell communication || cellular response to topologically incorrect protein || monoamine transport || positive regulation of protein ubiquitination || establishment of tissue polarity || phosphorylation || regulation of transforming growth factor beta receptor signaling pathway || positive regulation of protein metabolic process || single-organism process || cell communication || non-canonical Wnt receptor signaling pathway || epidermis morphogenesis || intrinsic apoptotic signaling pathway by p53 class mediator || catechol-containing compound metabolic process || embryonic development via the syncytial blastoderm || phosphatidylinositol metabolic process || positive regulation of stress-activated MAPK cascade || biological regulation || negative regulation of type I interferon production || catecholamine metabolic process || regulation of transcription from RNA polymerase II promoter in response to hypoxia || glycerophospholipid metabolic process || negative regulation of proteolysis || protein insertion into membrane || protein sumoylation || regulation of protein metabolic process || lymphocyte homeostasis || TRIF-dependent toll-like receptor signaling pathway || regulation of embryonic development || protein catabolic process || regulation of synaptic transmission || post-chaperonin tubulin folding pathway || regulation of JNK cascade || glycerolipid biosynthetic process || regulation of cell cycle arrest || regulation of type I interferon production || positive regulation of transforming growth factor beta receptor signaling pathway || organelle organization || lamellipodium morphogenesis || regulation of protein catabolic process || cellular process || localization within membrane || asymmetric protein localization || genetic imprinting || regulation of synapse assembly || regulation of protein binding || cell death || cytoskeletal anchoring at plasma membrane || death || synaptic transmission, dopaminergic || synaptonemal complex organization || regulation of signal transduction || tissue morphogenesis || regulation of DNA-dependent transcription in response to stress || establishment or maintenance of apical/basal cell polarity || regulation of nucleotide metabolic process || establishment or maintenance of cell polarity || dopamine uptake || regulation of synaptic growth at neuromuscular junction || regulation of phosphorus metabolic process || response to endoplasmic reticulum stress || single-organism cellular process || regulation of transcription elongation from RNA polymerase II promoter || negative regulation of signaling || cell morphogenesis || endoplasmic reticulum organization || single organism signaling || macromolecule metabolic process || positive regulation of cell communication || nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway || positive regulation of binding || protein autoubiquitination || response to topologically incorrect protein || phosphatidylinositol biosynthetic process || regulation of proteolysis || regulation of neurotransmitter transport || microvillus organization || cochlea morphogenesis || formation of primary germ layer || apical protein localization || signal transduction || autophagy || small GTPase mediated signal transduction || regulation of catalytic activity || microvillus assembly || Wnt receptor signaling pathway || glycerophospholipid biosynthetic process || establishment of planar polarity || negative regulation of synapse assembly || macrophage chemotaxis || axial mesoderm formation || cellular protein catabolic process || cytoskeleton organization || positive regulation of protein binding || positive regulation of signaling || negative regulation of protein metabolic process || startle response || germ-band shortening || axial mesoderm morphogenesis || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || macromolecule localization || positive regulation of GTPase activity || B cell activation || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.104 |
1.237 |
-- |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation || non-canonical Wnt receptor signaling pathway || Wnt receptor signaling pathway || T cell receptor signaling pathway |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation || peptidyl-tyrosine dephosphorylation || modification-dependent macromolecule catabolic process || phospholipid biosynthetic process || phosphatidylinositol phosphorylation || cellular protein metabolic process || protein modification by small protein conjugation or removal || protein ufmylation || dopamine metabolic process || monoubiquitinated protein deubiquitination || modification-dependent protein catabolic process || maintenance of DNA methylation || protein autoubiquitination || lipid modification || phosphatidylinositol biosynthetic process || protein linear polyubiquitination || autophagic vacuole assembly || phosphorylation || cellular macromolecule metabolic process || catechol-containing compound metabolic process || phosphatidylinositol metabolic process || lipid phosphorylation || autophagy || catecholamine metabolic process || macroautophagy || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || ER-associated protein catabolic process || protein sumoylation || cellular protein catabolic process || glycerolipid metabolic process || post-chaperonin tubulin folding pathway || glycerolipid biosynthetic process || proteolysis involved in cellular protein catabolic process || fatty acid elongation || cellular macromolecule catabolic process || phosphatidylinositol-3-phosphate biosynthetic process || norepinephrine metabolic process || cellular catabolic process || phospholipid metabolic process || genetic imprinting |
| Biological Process (BP) |
transmembrane receptor protein serine/threonine kinase signaling pathway |
0.9382 |
2.398 |
-- |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation |
| Biological Process (BP) |
regulation of multicellular organismal development |
1 |
1.268 |
-- |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || dorsal closure, elongation of leading edge cells || regulation of embryonic development || regulation of establishment of planar polarity || negative regulation of nervous system development || regulation of skeletal muscle fiber development || regulation of synapse assembly || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
multicellular organismal signaling |
0.1106 |
1.42 |
-- |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || regulation of synapse assembly || synaptic transmission, dopaminergic || synaptic transmission, glutamatergic || catecholamine uptake involved in synaptic transmission || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
cell-cell signaling |
0.8609 |
1.357 |
-- |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || synaptic transmission, dopaminergic || synaptic transmission, glutamatergic || catecholamine uptake involved in synaptic transmission || dopamine uptake involved in synaptic transmission || regulation of synapse assembly |
| Biological Process (BP) |
neurological system process |
0.01131 |
1.284 |
-- |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || synaptic transmission, dopaminergic || synaptic transmission, glutamatergic || catecholamine uptake involved in synaptic transmission || startle response || dopamine uptake involved in synaptic transmission || regulation of synapse assembly |
| Biological Process (BP) |
transmission of nerve impulse |
0.6311 |
1.42 |
-- |
INHERITED FROM: regulation of synapse assembly || negative regulation of synapse assembly || synaptic transmission, dopaminergic || synaptic transmission, glutamatergic || catecholamine uptake involved in synaptic transmission || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
cellular response to stimulus |
0.01011 |
0.7645 |
-- |
INHERITED FROM: stress-activated MAPK cascade || macrophage chemotaxis || response to endoplasmic reticulum stress || nucleotide-binding oligomerization domain containing signaling pathway || pathway-restricted SMAD protein phosphorylation || autophagic vacuole assembly || TRIF-dependent toll-like receptor signaling pathway || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular response to transforming growth factor beta stimulus || non-canonical Wnt receptor signaling pathway || intrinsic apoptotic signaling pathway by p53 class mediator || intrinsic apoptotic signaling pathway in response to DNA damage || signal transduction || toll-like receptor 2 signaling pathway || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || toll-like receptor 5 signaling pathway || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || T cell receptor signaling pathway || small GTPase mediated signal transduction || nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway || toll-like receptor 4 signaling pathway || macroautophagy || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || Wnt receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || cellular response to topologically incorrect protein || JNK cascade || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
response to stress |
0.4967 |
0.8125 |
-- |
INHERITED FROM: stress-activated MAPK cascade || response to endoplasmic reticulum stress || regulation of DNA-dependent transcription in response to stress || autophagic vacuole assembly || regulation of transcription from RNA polymerase II promoter in response to hypoxia || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || macroautophagy || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway in response to DNA damage || response to topologically incorrect protein || cellular response to topologically incorrect protein || JNK cascade || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
protein complex biogenesis |
0.9436 |
1.301 |
-- |
INHERITED FROM: protein polymerization || tubulin complex biogenesis || post-chaperonin tubulin folding pathway |
| Biological Process (BP) |
protein complex assembly |
1 |
1.319 |
-- |
INHERITED FROM: protein polymerization |
| Biological Process (BP) |
cellular protein complex assembly |
0.2382 |
1.658 |
-- |
INHERITED FROM: protein polymerization |
| Biological Process (BP) |
macromolecular complex assembly |
1 |
1.252 |
-- |
INHERITED FROM: protein polymerization |
| Biological Process (BP) |
cellular component organization |
0.109 |
0.6819 |
-- |
INHERITED FROM: protein insertion into membrane || synaptonemal complex assembly || positive regulation of cell size || dorsal closure, elongation of leading edge cells || autophagic vacuole assembly || cell morphogenesis || axon extension || cytoskeleton organization || cytoskeletal anchoring at plasma membrane || endoplasmic reticulum organization || microvillus organization || synapsis || synaptonemal complex organization || protein insertion into ER membrane || cytoplasmic microtubule organization || organelle organization || lamellipodium morphogenesis || membrane organization || cell junction organization || chromosome organization involved in meiosis || protein polymerization || microvillus assembly || cellular membrane organization |
| Biological Process (BP) |
cellular protein localization |
0.1328 |
1.337 |
-- |
INHERITED FROM: protein insertion into membrane || cytoskeletal anchoring at plasma membrane || protein insertion into ER membrane |
| Biological Process (BP) |
immune response-activating cell surface receptor signaling pathway |
0.01678 |
2.222 |
-- |
INHERITED FROM: T cell receptor signaling pathway |
| Biological Process (BP) |
immune response-regulating cell surface receptor signaling pathway |
0.511 |
2.222 |
-- |
INHERITED FROM: T cell receptor signaling pathway |
| Biological Process (BP) |
antigen receptor-mediated signaling pathway |
0.002432 |
2.699 |
-- |
INHERITED FROM: T cell receptor signaling pathway |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
0.5186 |
2.097 |
-- |
INHERITED FROM: regulation of synaptic transmission |
| Biological Process (BP) |
regulation of striated muscle tissue development |
0.03575 |
2.699 |
-- |
INHERITED FROM: regulation of skeletal muscle fiber development || regulation of synaptic growth at neuromuscular junction |
| Biological Process (BP) |
regulation of muscle organ development |
0.1357 |
2.699 |
-- |
INHERITED FROM: regulation of skeletal muscle fiber development || regulation of synaptic growth at neuromuscular junction |
| Biological Process (BP) |
regulation of muscle tissue development |
0.3391 |
2.699 |
-- |
INHERITED FROM: regulation of skeletal muscle fiber development || regulation of synaptic growth at neuromuscular junction |
| Biological Process (BP) |
system development |
0.735 |
0.8069 |
-- |
INHERITED FROM: axon extension || epidermis morphogenesis || cochlea morphogenesis || ommatidial rotation || chaeta morphogenesis || cochlea development |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
0.7995 |
1.745 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
neurogenesis |
0.006855 |
1.357 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
neuron differentiation |
0.003045 |
1.658 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
neuron projection development |
1 |
1.921 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
cell development |
1 |
1.222 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
developmental cell growth |
0.07042 |
2.398 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
neuron development |
0.002244 |
1.796 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
cell morphogenesis involved in neuron differentiation |
0.6077 |
1.921 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
neuron projection morphogenesis |
0.9804 |
2 |
-- |
INHERITED FROM: axon extension |
| Biological Process (BP) |
negative regulation of growth |
0.2166 |
1.854 |
-- |
INHERITED FROM: negative regulation of developmental growth |
| Biological Process (BP) |
mesoderm development |
0.02213 |
2.699 |
-- |
INHERITED FROM: axial mesoderm development || axial mesoderm morphogenesis || axial mesoderm formation |
| Biological Process (BP) |
response to chemical stimulus |
1 |
0.8861 |
-- |
INHERITED FROM: macrophage chemotaxis || response to transforming growth factor beta stimulus || cellular response to transforming growth factor beta stimulus || regulation of transcription from RNA polymerase II promoter in response to hypoxia || response to topologically incorrect protein || cellular response to topologically incorrect protein |
| Biological Process (BP) |
cell migration |
0.5084 |
1.658 |
-- |
INHERITED FROM: macrophage chemotaxis || leukocyte migration |
| Biological Process (BP) |
cell motility |
0.3106 |
1.585 |
-- |
INHERITED FROM: macrophage chemotaxis || leukocyte migration |
| Biological Process (BP) |
leukocyte chemotaxis |
0.2339 |
2.398 |
-- |
INHERITED FROM: macrophage chemotaxis |
| Biological Process (BP) |
taxis |
0.2944 |
1.921 |
-- |
INHERITED FROM: macrophage chemotaxis |
| Biological Process (BP) |
cell chemotaxis |
0.00911 |
2.222 |
-- |
INHERITED FROM: macrophage chemotaxis |
| Biological Process (BP) |
regulation of cell size |
0.2404 |
2.222 |
-- |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
regulation of nucleotide catabolic process |
1 |
2 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity |
| Biological Process (BP) |
regulation of GTP catabolic process |
0.01957 |
2.097 |
-- |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity |
| Biological Process (BP) |
positive regulation of hydrolase activity |
0.4655 |
1.62 |
-- |
INHERITED FROM: positive regulation of GTPase activity |
| Biological Process (BP) |
organic substance metabolic process |
0.4044 |
0.2676 |
-- |
INHERITED FROM: macromolecule modification || pathway-restricted SMAD protein phosphorylation || peptidyl-tyrosine dephosphorylation || modification-dependent macromolecule catabolic process || phospholipid biosynthetic process || phosphatidylinositol phosphorylation || cellular protein metabolic process || protein modification process || proteolysis || protein metabolic process || protein modification by small protein conjugation or removal || protein ufmylation || dopamine metabolic process || macromolecule metabolic process || monoubiquitinated protein deubiquitination || modification-dependent protein catabolic process || maintenance of DNA methylation || protein autoubiquitination || organic substance catabolic process || lipid modification || phosphatidylinositol biosynthetic process || protein linear polyubiquitination || cellular macromolecule metabolic process || catechol-containing compound metabolic process || phosphatidylinositol metabolic process || lipid phosphorylation || catecholamine metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || ER-associated protein catabolic process || protein sumoylation || cellular protein catabolic process || protein catabolic process || glycerolipid metabolic process || post-chaperonin tubulin folding pathway || glycerolipid biosynthetic process || macromolecule catabolic process || proteolysis involved in cellular protein catabolic process || fatty acid elongation || cellular macromolecule catabolic process || phosphatidylinositol-3-phosphate biosynthetic process || norepinephrine metabolic process || phospholipid metabolic process || genetic imprinting |
| Biological Process (BP) |
regulation of MAPK cascade |
0.656 |
1.699 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity || positive regulation of stress-activated MAPK cascade || regulation of JNK cascade |
| Biological Process (BP) |
positive regulation of intracellular protein kinase cascade |
0.004943 |
1.658 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity || positive regulation of stress-activated MAPK cascade |
| Biological Process (BP) |
positive regulation of protein phosphorylation |
0.3639 |
1.745 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of kinase activity |
0.03803 |
1.854 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of phosphorylation |
0.1145 |
1.469 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of phosphorylation |
0.003215 |
1.745 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of protein kinase activity |
0.008157 |
1.62 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of protein kinase activity |
0.006902 |
1.854 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of phosphate metabolic process |
0.1535 |
1.699 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of transferase activity |
0.002404 |
1.62 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of transferase activity |
0.00307 |
1.854 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of protein serine/threonine kinase activity |
1 |
1.854 |
-- |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway |
0.4528 |
2.097 |
-- |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway in response to DNA damage || intrinsic apoptotic signaling pathway by p53 class mediator || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress |
| Biological Process (BP) |
organonitrogen compound metabolic process |
1 |
0.699 |
-- |
INHERITED FROM: dopamine metabolic process || catecholamine metabolic process || norepinephrine metabolic process |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
0.4705 |
1.301 |
-- |
INHERITED FROM: negative regulation of protein catabolic process || negative regulation of proteasomal protein catabolic process || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of protein metabolic process || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of DNA-dependent transcription, elongation || negative regulation of proteolysis |
| Biological Process (BP) |
leukocyte activation |
0.0296 |
1.553 |
-- |
INHERITED FROM: B cell activation |
| Biological Process (BP) |
lymphocyte activation |
0.4935 |
1.699 |
-- |
INHERITED FROM: B cell activation |
| Biological Process (BP) |
immune response-activating signal transduction |
0.06268 |
2.097 |
-- |
INHERITED FROM: TRIF-dependent toll-like receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 4 signaling pathway || T cell receptor signaling pathway |
| Biological Process (BP) |
activation of innate immune response |
0.08132 |
2.699 |
-- |
INHERITED FROM: TRIF-dependent toll-like receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
innate immune response-activating signal transduction |
0.08243 |
2.699 |
-- |
INHERITED FROM: TRIF-dependent toll-like receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
protein modification by small protein removal |
1 |
2.699 |
-- |
INHERITED FROM: monoubiquitinated protein deubiquitination |
| Biological Process (BP) |
regulation of transport |
0.7673 |
1.155 |
-- |
INHERITED FROM: regulation of catenin import into nucleus || regulation of neurotransmitter transport |
| Biological Process (BP) |
regulation of protein import into nucleus |
0.1754 |
2.222 |
-- |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of protein transport |
0.2695 |
1.658 |
-- |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of cellular localization |
0.4448 |
1.357 |
-- |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of establishment of protein localization |
0.2387 |
1.62 |
-- |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
neuron-neuron synaptic transmission |
0.01252 |
2.398 |
-- |
INHERITED FROM: synaptic transmission, glutamatergic || synaptic transmission, dopaminergic || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
1 |
1.027 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || regulation of GTPase activity || negative regulation of DNA-dependent transcription, elongation || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || regulation of purine nucleotide metabolic process |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
1 |
1.237 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1 |
1.066 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of RNA metabolic process |
1 |
1.131 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
1 |
1.119 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
1 |
1.167 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
1 |
1.009 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of DNA-dependent transcription, elongation |
0.001742 |
2.699 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
0.9538 |
1.658 |
-- |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
positive regulation of immune response |
1 |
1.796 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || T cell receptor signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway |
| Biological Process (BP) |
positive regulation of defense response |
0.6825 |
2.398 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway |
| Biological Process (BP) |
positive regulation of innate immune response |
0.165 |
2.699 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || TRIF-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway |
| Biological Process (BP) |
regulation of defense response |
1 |
1.658 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor 5 signaling pathway || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
regulation of stress-activated MAPK cascade |
0.001273 |
2.398 |
-- |
INHERITED FROM: positive regulation of stress-activated MAPK cascade || regulation of JNK cascade |
| Biological Process (BP) |
positive regulation of response to stimulus |
0.004921 |
1.284 |
-- |
INHERITED FROM: positive regulation of stress-activated MAPK cascade || toll-like receptor 2 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || positive regulation of transforming growth factor beta receptor signaling pathway || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || positive regulation of MAP kinase activity || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
0.9908 |
1.854 |
-- |
INHERITED FROM: negative regulation of DNA-dependent transcription, elongation || negative regulation of transcription elongation from RNA polymerase II promoter |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
1 |
1.796 |
-- |
INHERITED FROM: negative regulation of DNA-dependent transcription, elongation || negative regulation of transcription elongation from RNA polymerase II promoter |
| Biological Process (BP) |
negative regulation of cytokine production |
0.04772 |
2.398 |
-- |
INHERITED FROM: negative regulation of type I interferon production |
| Biological Process (BP) |
regulation of proteasomal ubiquitin-dependent protein catabolic process |
0.04624 |
2.398 |
-- |
INHERITED FROM: negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
regulation of biological process |
0.08752 |
0.4486 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || pathway-restricted SMAD protein phosphorylation || negative regulation of response to stimulus || positive regulation of cell cycle arrest || T cell receptor signaling pathway || regulation of cell communication || negative regulation of catabolic process || toll-like receptor 4 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || regulation of purine nucleotide metabolic process || negative regulation of cell-cell adhesion || negative regulation of Wnt receptor signaling pathway || negative regulation of nervous system development || intrinsic apoptotic signaling pathway in response to DNA damage || negative regulation of cellular catabolic process || regulation of catenin import into nucleus || regulation of phosphate metabolic process || regulation of cellular catabolic process || regulation of nucleoside metabolic process || maintenance of DNA methylation || positive regulation of MAP kinase activity || regulation of protein stability || regulation of establishment or maintenance of cell polarity || MyD88-dependent toll-like receptor signaling pathway || negative regulation of cell communication || JNK cascade || regulation of Wnt receptor signaling pathway || positive regulation of protein ubiquitination || positive regulation of type I interferon production || regulation of transforming growth factor beta receptor signaling pathway || positive regulation of protein metabolic process || regulation of stress-activated protein kinase signaling cascade || non-canonical Wnt receptor signaling pathway || intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of stress-activated MAPK cascade || negative regulation of type I interferon production || regulation of transcription from RNA polymerase II promoter in response to hypoxia || toll-like receptor 5 signaling pathway || negative regulation of DNA-dependent transcription, elongation || negative regulation of proteolysis || regulation of proteasomal protein catabolic process || regulation of anatomical structure morphogenesis || nucleotide-binding oligomerization domain containing signaling pathway || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of protein metabolic process || regulation of cell shape || regulation of protein ubiquitination || TRIF-dependent toll-like receptor signaling pathway || regulation of embryonic development || regulation of synaptic transmission || regulation of JNK cascade || regulation of cell cycle arrest || regulation of type I interferon production || positive regulation of transforming growth factor beta receptor signaling pathway || regulation of intracellular protein kinase cascade || regulation of protein catabolic process || genetic imprinting || regulation of synapse assembly || dorsal closure, elongation of leading edge cells || regulation of signal transduction || regulation of DNA-dependent transcription in response to stress || regulation of nucleotide metabolic process || stress-activated protein kinase signaling cascade || regulation of synaptic growth at neuromuscular junction || regulation of phosphorus metabolic process || regulation of transcription elongation from RNA polymerase II promoter || negative regulation of signaling || regulation of signaling || regulation of catabolic process || regulation of establishment of planar polarity || regulation of cellular protein metabolic process || regulation of skeletal muscle fiber development || negative regulation of proteasomal protein catabolic process || positive regulation of cell communication || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway || toll-like receptor 3 signaling pathway || regulation of proteolysis || stress-activated MAPK cascade || regulation of neurotransmitter transport || regulation of cellular process || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || signal transduction || regulation of cell morphogenesis || regulation of GTPase activity || small GTPase mediated signal transduction || positive regulation of cellular protein metabolic process || regulation of catalytic activity || negative regulation of developmental growth || Wnt receptor signaling pathway || negative regulation of synapse assembly || positive regulation of phosphorus metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || negative regulation of protein catabolic process || positive regulation of signaling || negative regulation of protein metabolic process || toll-like receptor 2 signaling pathway || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of GTPase activity || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
negative regulation of biological process |
0.7411 |
0.8665 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || negative regulation of response to stimulus || negative regulation of type I interferon production || negative regulation of DNA-dependent transcription, elongation || negative regulation of catabolic process || negative regulation of developmental growth || negative regulation of proteolysis || negative regulation of cell-cell adhesion || negative regulation of synapse assembly || negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of Wnt receptor signaling pathway || negative regulation of signaling || negative regulation of protein catabolic process || negative regulation of nervous system development || negative regulation of protein metabolic process || negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of cell communication |
| Biological Process (BP) |
positive regulation of biological process |
1 |
0.8182 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of type I interferon production || positive regulation of protein metabolic process || positive regulation of cell cycle arrest || positive regulation of stress-activated MAPK cascade || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of cellular protein metabolic process || cytoplasmic pattern recognition receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || positive regulation of phosphorus metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || TRIF-dependent toll-like receptor signaling pathway || positive regulation of signaling || toll-like receptor 2 signaling pathway || positive regulation of transforming growth factor beta receptor signaling pathway || positive regulation of cell communication || positive regulation of MAP kinase activity || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0.9804 |
1.208 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of phosphorus metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of cellular protein metabolic process || positive regulation of MAP kinase activity |
| Biological Process (BP) |
protein complex subunit organization |
0.06922 |
1.194 |
-- |
INHERITED FROM: cytoplasmic microtubule organization || protein polymerization |
| Biological Process (BP) |
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
0.7435 |
2.398 |
-- |
INHERITED FROM: positive regulation of transforming growth factor beta receptor signaling pathway || regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
0.3915 |
2.699 |
-- |
INHERITED FROM: positive regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
organic acid metabolic process |
1 |
0.8239 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
fatty acid biosynthetic process |
0.5309 |
1.699 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
organic acid biosynthetic process |
1 |
1.108 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
carboxylic acid metabolic process |
1 |
0.8416 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
oxoacid metabolic process |
1 |
0.8297 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
single-organism biosynthetic process |
1 |
0.983 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
carboxylic acid biosynthetic process |
1 |
1.108 |
-- |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
ubiquitin-dependent protein catabolic process |
0.9107 |
2.097 |
-- |
INHERITED FROM: ER-associated protein catabolic process |
| Biological Process (BP) |
proteasomal ubiquitin-dependent protein catabolic process |
1 |
2.398 |
-- |
INHERITED FROM: ER-associated protein catabolic process |
| Biological Process (BP) |
negative regulation of cell adhesion |
0.1608 |
2.699 |
-- |
INHERITED FROM: negative regulation of cell-cell adhesion |
| Biological Process (BP) |
molting cycle |
0.118 |
2.222 |
-- |
INHERITED FROM: molting cycle, collagen and cuticulin-based cuticle |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.2215 |
1.658 |
-- |
INHERITED FROM: ommatidial rotation || neural plate morphogenesis || dorsal closure, elongation of leading edge cells || initiation of dorsal closure || convergent extension || establishment of planar polarity |
| Biological Process (BP) |
morphogenesis of a polarized epithelium |
0.04113 |
2.699 |
-- |
INHERITED FROM: ommatidial rotation || establishment of planar polarity |
| Biological Process (BP) |
eye development |
1 |
1.62 |
-- |
INHERITED FROM: ommatidial rotation |
| Biological Process (BP) |
cellular homeostasis |
1 |
1.284 |
-- |
INHERITED FROM: ubiquitin homeostasis |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
1 |
0.7305 |
-- |
INHERITED FROM: maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
1 |
0.585 |
-- |
INHERITED FROM: maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
DNA modification |
0.5727 |
2.097 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
DNA alkylation |
0.0216 |
2.398 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
DNA methylation |
0.0216 |
2.398 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
methylation |
0.9217 |
1.854 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
macromolecule methylation |
1 |
1.854 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
nucleic acid metabolic process |
1 |
0.9066 |
-- |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
regionalization |
1 |
2.222 |
-- |
INHERITED FROM: dorsal/ventral axis specification |
| Biological Process (BP) |
axis specification |
0.005549 |
2.398 |
-- |
INHERITED FROM: dorsal/ventral axis specification |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.6421 |
-- |
INHERITED FROM: catechol-containing compound metabolic process || catecholamine metabolic process || dopamine metabolic process || fatty acid elongation || norepinephrine metabolic process |
| Biological Process (BP) |
metabolic process |
0.3688 |
0.2411 |
-- |
INHERITED FROM: catabolic process || macromolecule modification || pathway-restricted SMAD protein phosphorylation || peptidyl-tyrosine dephosphorylation || modification-dependent macromolecule catabolic process || phospholipid biosynthetic process || phosphatidylinositol phosphorylation || cellular protein metabolic process || protein modification process || proteolysis || protein metabolic process || protein modification by small protein conjugation or removal || protein ufmylation || dopamine metabolic process || macromolecule metabolic process || monoubiquitinated protein deubiquitination || modification-dependent protein catabolic process || maintenance of DNA methylation || protein autoubiquitination || organic substance catabolic process || lipid modification || phosphatidylinositol biosynthetic process || protein linear polyubiquitination || autophagic vacuole assembly || phosphorylation || cellular macromolecule metabolic process || catechol-containing compound metabolic process || phosphatidylinositol metabolic process || lipid phosphorylation || autophagy || catecholamine metabolic process || macroautophagy || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || ER-associated protein catabolic process || protein sumoylation || cellular protein catabolic process || protein catabolic process || glycerolipid metabolic process || post-chaperonin tubulin folding pathway || glycerolipid biosynthetic process || macromolecule catabolic process || proteolysis involved in cellular protein catabolic process || fatty acid elongation || cellular macromolecule catabolic process || phosphatidylinositol-3-phosphate biosynthetic process || norepinephrine metabolic process || cellular catabolic process || phospholipid metabolic process || genetic imprinting |
| Biological Process (BP) |
programmed cell death |
1 |
1.553 |
-- |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
regulation of synapse structure and activity |
0.003447 |
2.699 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of synapse assembly || negative regulation of synapse assembly |
| Biological Process (BP) |
regulation of synapse organization |
0.001783 |
2.699 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of synapse assembly || negative regulation of synapse assembly |
| Biological Process (BP) |
regulation of cell differentiation |
1 |
1.357 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of skeletal muscle fiber development |
| Biological Process (BP) |
regulation of skeletal muscle tissue development |
0.001726 |
2.699 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of skeletal muscle fiber development |
| Biological Process (BP) |
regulation of muscle cell differentiation |
0.02754 |
2.699 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of skeletal muscle fiber development |
| Biological Process (BP) |
regulation of striated muscle cell differentiation |
0.003188 |
2.699 |
-- |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of skeletal muscle fiber development |
| Biological Process (BP) |
developmental growth involved in morphogenesis |
0.02166 |
2.097 |
-- |
INHERITED FROM: dorsal closure, elongation of leading edge cells || axon extension |
| Biological Process (BP) |
dorsal closure |
0.001662 |
2.699 |
-- |
INHERITED FROM: dorsal closure, elongation of leading edge cells || initiation of dorsal closure |
| Biological Process (BP) |
cellular developmental process |
1 |
0.9666 |
-- |
INHERITED FROM: dorsal closure, elongation of leading edge cells || cell morphogenesis || axon extension || lamellipodium morphogenesis |
| Biological Process (BP) |
unidimensional cell growth |
0.06168 |
2.398 |
-- |
INHERITED FROM: dorsal closure, elongation of leading edge cells |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.9699 |
1.469 |
-- |
INHERITED FROM: germ-band shortening || neural plate morphogenesis || neural plate development || embryonic development via the syncytial blastoderm || dorsal closure, elongation of leading edge cells || initiation of dorsal closure |
| Biological Process (BP) |
intracellular protein kinase cascade |
0.7651 |
1.745 |
-- |
INHERITED FROM: JNK cascade || stress-activated protein kinase signaling cascade || stress-activated MAPK cascade |
| Biological Process (BP) |
cellular component assembly |
0.006544 |
1.076 |
-- |
INHERITED FROM: synaptonemal complex assembly || protein polymerization || microvillus assembly || autophagic vacuole assembly |
| Biological Process (BP) |
meiosis I |
0.001803 |
2.222 |
-- |
INHERITED FROM: synapsis || synaptonemal complex assembly |
| Biological Process (BP) |
maintenance of protein location in cell |
0.001097 |
2.398 |
-- |
INHERITED FROM: cytoskeletal anchoring at plasma membrane |
| Biological Process (BP) |
maintenance of protein location |
0.006369 |
2.222 |
-- |
INHERITED FROM: cytoskeletal anchoring at plasma membrane |
| Biological Process (BP) |
primary metabolic process |
0.009684 |
0.2976 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || protein linear polyubiquitination || pathway-restricted SMAD protein phosphorylation || peptidyl-tyrosine dephosphorylation || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation || phosphatidylinositol phosphorylation || cellular protein metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || protein modification process || ER-associated protein catabolic process || proteolysis || protein sumoylation || protein metabolic process || cellular protein catabolic process || protein modification by small protein conjugation or removal || protein catabolic process || glycerolipid metabolic process || protein ufmylation || post-chaperonin tubulin folding pathway || glycerolipid biosynthetic process || monoubiquitinated protein deubiquitination || proteolysis involved in cellular protein catabolic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || modification-dependent protein catabolic process || maintenance of DNA methylation || genetic imprinting || protein autoubiquitination || lipid modification |
| Biological Process (BP) |
phosphorus metabolic process |
0.09619 |
0.8013 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || phosphatidylinositol phosphorylation || pathway-restricted SMAD protein phosphorylation || phosphorylation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || peptidyl-tyrosine dephosphorylation || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation |
| Biological Process (BP) |
lipid metabolic process |
0.7459 |
0.9431 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || phosphatidylinositol phosphorylation || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || glycerolipid metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation || lipid modification |
| Biological Process (BP) |
organophosphate biosynthetic process |
0.01422 |
1.155 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || glycerophospholipid biosynthetic process || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
cellular biosynthetic process |
1 |
0.5498 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
organic substance biosynthetic process |
1 |
0.5376 |
-- |
INHERITED FROM: phosphatidylinositol biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
intracellular receptor signaling pathway |
0.8579 |
2.699 |
-- |
INHERITED FROM: cytoplasmic pattern recognition receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |
| Biological Process (BP) |
multicellular organismal development |
0.9121 |
0.7496 |
-- |
INHERITED FROM: neural plate development || dorsal closure, elongation of leading edge cells || embryo development || axon extension || embryonic morphogenesis || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || formation of primary germ layer || embryonic development via the syncytial blastoderm || dorsal/ventral axis specification || neural plate morphogenesis || axial mesoderm formation || ommatidial rotation || germ-band shortening || collagen and cuticulin-based cuticle development || chaeta morphogenesis || cochlea development |
| Biological Process (BP) |
anatomical structure development |
0.06928 |
0.7212 |
-- |
INHERITED FROM: neural plate development || establishment of tissue polarity || dorsal closure, elongation of leading edge cells || embryo development || axon extension || embryonic morphogenesis || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || post-anal tail morphogenesis || formation of primary germ layer || embryonic development via the syncytial blastoderm || tissue morphogenesis || ectoderm development || neural plate morphogenesis || establishment of planar polarity || axial mesoderm formation || cell morphogenesis || convergent extension || axial mesoderm development || ommatidial rotation || germ-band shortening || axial mesoderm morphogenesis || collagen and cuticulin-based cuticle development || lamellipodium morphogenesis || chaeta morphogenesis || cochlea development |
| Biological Process (BP) |
single-multicellular organism process |
1 |
0.6383 |
-- |
INHERITED FROM: neural plate development || neurotransmitter uptake || synaptic transmission, glutamatergic || dorsal closure, elongation of leading edge cells || embryo development || dopamine uptake involved in synaptic transmission || synaptic transmission, dopaminergic || embryonic morphogenesis || neural plate morphogenesis || regulation of synaptic growth at neuromuscular junction || ommatidial rotation || molting cycle, collagen and cuticulin-based cuticle || catecholamine uptake involved in synaptic transmission || axon extension || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || formation of primary germ layer || embryonic development via the syncytial blastoderm || dorsal/ventral axis specification || negative regulation of synapse assembly || axial mesoderm formation || startle response || germ-band shortening || collagen and cuticulin-based cuticle development || chaeta morphogenesis || cochlea development || regulation of synapse assembly |
| Biological Process (BP) |
homeostasis of number of cells |
0.03023 |
1.796 |
-- |
INHERITED FROM: leukocyte homeostasis || B cell homeostasis || lymphocyte homeostasis |
| Biological Process (BP) |
transport |
1 |
0.7747 |
-- |
INHERITED FROM: neurotransmitter uptake || dopamine transport || dopamine uptake involved in synaptic transmission || catecholamine uptake involved in synaptic transmission || catecholamine uptake || dopamine uptake || monoamine transport || catecholamine transport |
| Biological Process (BP) |
single-organism transport |
1 |
0.8013 |
-- |
INHERITED FROM: neurotransmitter uptake || dopamine transport || dopamine uptake involved in synaptic transmission || catecholamine uptake involved in synaptic transmission || catecholamine uptake || dopamine uptake || monoamine transport || catecholamine transport |
| Biological Process (BP) |
establishment of localization |
1 |
0.7696 |
-- |
INHERITED FROM: neurotransmitter uptake || dopamine transport || dopamine uptake involved in synaptic transmission || catecholamine uptake involved in synaptic transmission || catecholamine uptake || dopamine uptake || monoamine transport || catecholamine transport |
| Biological Process (BP) |
response to extracellular stimulus |
0.3482 |
1.699 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
response to nutrient levels |
0.01482 |
1.699 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
cellular response to extracellular stimulus |
0.5541 |
1.921 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
cellular response to nutrient levels |
0.2952 |
1.921 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
response to starvation |
0.00666 |
1.796 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
cellular response to external stimulus |
0.5617 |
1.921 |
-- |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
vacuole organization |
0.09315 |
1.854 |
-- |
INHERITED FROM: autophagic vacuole assembly |
| Biological Process (BP) |
protein metabolic process |
0 |
0.6383 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
0.000962 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
6.322e-12 |
0.4976 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
1.493e-11 |
0.3915 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
9.964e-09 |
0.5317 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular component organization or biogenesis |
1.158e-14 |
0.6536 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0.001512 |
0.5498 |
Least Informative |
INHERITED FROM: stress-activated MAPK cascade || pathway-restricted SMAD protein phosphorylation || autophagic vacuole assembly || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular response to transforming growth factor beta stimulus || non-canonical Wnt receptor signaling pathway || intrinsic apoptotic signaling pathway by p53 class mediator || signal transduction || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || small GTPase mediated signal transduction || toll-like receptor 4 signaling pathway || macroautophagy || cytoplasmic pattern recognition receptor signaling pathway || Wnt receptor signaling pathway || stress-activated protein kinase signaling cascade || macrophage chemotaxis || response to endoplasmic reticulum stress || nucleotide-binding oligomerization domain containing signaling pathway || response to transforming growth factor beta stimulus || TRIF-dependent toll-like receptor signaling pathway || startle response || intrinsic apoptotic signaling pathway in response to DNA damage || toll-like receptor 2 signaling pathway || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway || toll-like receptor 3 signaling pathway || response to topologically incorrect protein || MyD88-dependent toll-like receptor signaling pathway || cellular response to topologically incorrect protein || JNK cascade |
| Biological Process (BP) |
localization |
0.06121 |
0.6946 |
Least Informative |
INHERITED FROM: protein insertion into membrane || neurotransmitter uptake || macrophage chemotaxis || cellular macromolecule localization || dopamine transport || dopamine uptake involved in synaptic transmission || cytoskeletal anchoring at plasma membrane || catecholamine uptake involved in synaptic transmission || leukocyte migration || catecholamine uptake || apical protein localization || protein insertion into ER membrane || localization within membrane || asymmetric protein localization || macromolecule localization || protein localization || maintenance of location || maintenance of location in cell || dopamine uptake || monoamine transport || catecholamine transport |
| Biological Process (BP) |
regulation of metabolic process |
1 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of proteolysis || positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || positive regulation of protein metabolic process || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || regulation of GTPase activity || negative regulation of DNA-dependent transcription, elongation || regulation of nucleotide metabolic process || negative regulation of catabolic process || positive regulation of cellular protein metabolic process || regulation of catalytic activity || regulation of purine nucleotide metabolic process || negative regulation of proteolysis || regulation of proteasomal protein catabolic process || regulation of phosphorus metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of protein metabolic process || regulation of transcription elongation from RNA polymerase II promoter || positive regulation of phosphorus metabolic process || regulation of protein ubiquitination || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || negative regulation of protein catabolic process || regulation of catabolic process || negative regulation of protein metabolic process || regulation of cellular protein metabolic process || negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || regulation of phosphate metabolic process || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of cellular catabolic process || regulation of protein catabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || maintenance of DNA methylation || genetic imprinting || positive regulation of MAP kinase activity || regulation of protein stability || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
heterocycle metabolic process |
1 |
0.6308 |
Least Informative |
INHERITED FROM: maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
1 |
0.6271 |
Least Informative |
INHERITED FROM: catechol-containing compound metabolic process || catecholamine metabolic process || dopamine metabolic process || norepinephrine metabolic process || maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
organic cyclic compound metabolic process |
1 |
0.5817 |
Least Informative |
INHERITED FROM: catechol-containing compound metabolic process || catecholamine metabolic process || dopamine metabolic process || norepinephrine metabolic process || maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
biosynthetic process |
1 |
0.52 |
Least Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || glycerophospholipid biosynthetic process |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5376 |
Least Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || catechol-containing compound metabolic process || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation || phosphatidylinositol phosphorylation || catecholamine metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || glycerolipid metabolic process || glycerolipid biosynthetic process || dopamine metabolic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || norepinephrine metabolic process || phospholipid metabolic process || lipid modification |
| Biological Process (BP) |
nitrogen compound metabolic process |
1 |
0.5171 |
Least Informative |
INHERITED FROM: catecholamine metabolic process || dopamine metabolic process || norepinephrine metabolic process || maintenance of DNA methylation || genetic imprinting |
| Biological Process (BP) |
multicellular organismal process |
0.01212 |
0.6091 |
Least Informative |
INHERITED FROM: neural plate development || neurotransmitter uptake || synaptic transmission, glutamatergic || dorsal closure, elongation of leading edge cells || embryo development || dopamine uptake involved in synaptic transmission || synaptic transmission, dopaminergic || embryonic morphogenesis || neural plate morphogenesis || regulation of synaptic growth at neuromuscular junction || ommatidial rotation || molting cycle, collagen and cuticulin-based cuticle || catecholamine uptake involved in synaptic transmission || axon extension || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || formation of primary germ layer || embryonic development via the syncytial blastoderm || dorsal/ventral axis specification || negative regulation of synapse assembly || axial mesoderm formation || startle response || germ-band shortening || collagen and cuticulin-based cuticle development || chaeta morphogenesis || cochlea development || regulation of synapse assembly |
| Biological Process (BP) |
organelle organization |
2.615e-08 |
0.8996 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
signal transduction |
7.148e-07 |
0.9914 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
1.132e-07 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
1.372e-09 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
macromolecule localization |
2.239e-10 |
1.046 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular catabolic process |
4.181e-10 |
0.8928 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein metabolic process |
0 |
1.119 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of molecular function |
6.905e-07 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organic substance catabolic process |
0.0002896 |
0.8297 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular protein modification process |
0.1709 |
0.9066 |
Moderately Informative |
INHERITED FROM: protein linear polyubiquitination || protein sumoylation || monoubiquitinated protein deubiquitination || pathway-restricted SMAD protein phosphorylation || protein modification by small protein conjugation or removal || protein autoubiquitination || protein ufmylation || peptidyl-tyrosine dephosphorylation |
| Biological Process (BP) |
response to endogenous stimulus |
1 |
1.237 |
Moderately Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || response to transforming growth factor beta stimulus |
| Biological Process (BP) |
response to organic substance |
0.3874 |
1.018 |
Moderately Informative |
INHERITED FROM: response to transforming growth factor beta stimulus || cellular response to transforming growth factor beta stimulus || response to topologically incorrect protein || cellular response to topologically incorrect protein |
| Biological Process (BP) |
regulation of response to stimulus |
0.003261 |
0.9914 |
Moderately Informative |
INHERITED FROM: nucleotide-binding oligomerization domain containing signaling pathway || negative regulation of Wnt receptor signaling pathway || regulation of transforming growth factor beta receptor signaling pathway || negative regulation of response to stimulus || regulation of stress-activated protein kinase signaling cascade || TRIF-dependent toll-like receptor signaling pathway || regulation of JNK cascade || positive regulation of stress-activated MAPK cascade || toll-like receptor 2 signaling pathway || regulation of signal transduction || positive regulation of transforming growth factor beta receptor signaling pathway || regulation of intracellular protein kinase cascade || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || positive regulation of MAP kinase activity || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || regulation of Wnt receptor signaling pathway |
| Biological Process (BP) |
response to abiotic stimulus |
1 |
1.108 |
Moderately Informative |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
negative regulation of cellular process |
0.9269 |
0.9355 |
Moderately Informative |
INHERITED FROM: negative regulation of synapse assembly || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of Wnt receptor signaling pathway || negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of DNA-dependent transcription, elongation || negative regulation of cell communication || negative regulation of proteolysis || negative regulation of cell-cell adhesion |
| Biological Process (BP) |
regulation of developmental process |
0.01668 |
1.155 |
Moderately Informative |
INHERITED FROM: negative regulation of synapse assembly || regulation of anatomical structure morphogenesis || regulation of synaptic growth at neuromuscular junction || regulation of cell shape || dorsal closure, elongation of leading edge cells || regulation of embryonic development || regulation of establishment of planar polarity || negative regulation of nervous system development || regulation of skeletal muscle fiber development || regulation of cell morphogenesis || negative regulation of developmental growth || regulation of synapse assembly || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
regulation of cellular component organization |
0.01774 |
1.18 |
Moderately Informative |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || regulation of cell morphogenesis || regulation of cell shape || dorsal closure, elongation of leading edge cells || regulation of synapse assembly |
| Biological Process (BP) |
system process |
0.5541 |
1.131 |
Moderately Informative |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || synaptic transmission, glutamatergic || dopamine uptake involved in synaptic transmission || synaptic transmission, dopaminergic || catecholamine uptake involved in synaptic transmission || startle response || regulation of synapse assembly |
| Biological Process (BP) |
regulation of localization |
0.9427 |
1.066 |
Moderately Informative |
INHERITED FROM: regulation of neurotransmitter transport || regulation of catenin import into nucleus |
| Biological Process (BP) |
cellular response to stress |
0.001589 |
1.086 |
Moderately Informative |
INHERITED FROM: stress-activated MAPK cascade || response to endoplasmic reticulum stress || macroautophagy || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || regulation of DNA-dependent transcription in response to stress || autophagic vacuole assembly || regulation of transcription from RNA polymerase II promoter in response to hypoxia || intrinsic apoptotic signaling pathway in response to DNA damage || cellular response to topologically incorrect protein || JNK cascade || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
macromolecular complex subunit organization |
0.9102 |
1.131 |
Moderately Informative |
INHERITED FROM: protein polymerization || cytoplasmic microtubule organization |
| Biological Process (BP) |
cellular localization |
0.004641 |
1.027 |
Moderately Informative |
INHERITED FROM: protein insertion into membrane || cellular macromolecule localization || protein insertion into ER membrane || localization within membrane || cytoskeletal anchoring at plasma membrane || maintenance of location in cell |
| Biological Process (BP) |
organ development |
1 |
0.9355 |
Moderately Informative |
INHERITED FROM: epidermis morphogenesis || cochlea morphogenesis || ommatidial rotation || chaeta morphogenesis || cochlea development |
| Biological Process (BP) |
nervous system development |
0.001738 |
1.194 |
Moderately Informative |
INHERITED FROM: axon extension |
| Biological Process (BP) |
cell differentiation |
1 |
1.009 |
Moderately Informative |
INHERITED FROM: axon extension |
| Biological Process (BP) |
cellular response to chemical stimulus |
1 |
1.097 |
Moderately Informative |
INHERITED FROM: macrophage chemotaxis || regulation of transcription from RNA polymerase II promoter in response to hypoxia || cellular response to transforming growth factor beta stimulus || cellular response to topologically incorrect protein |
| Biological Process (BP) |
regulation of gene expression |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation || maintenance of DNA methylation || regulation of protein stability |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || regulation of GTPase activity || negative regulation of DNA-dependent transcription, elongation || regulation of nucleotide metabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || regulation of purine nucleotide metabolic process |
| Biological Process (BP) |
regulation of biosynthetic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
immune system process |
0.8003 |
1.076 |
Moderately Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || macrophage chemotaxis || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 5 signaling pathway || lymphocyte homeostasis || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || leukocyte migration || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || B cell activation || leukocyte homeostasis || B cell homeostasis |
| Biological Process (BP) |
regulation of cellular metabolic process |
1 |
0.7905 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to hypoxia || regulation of GTPase activity || negative regulation of DNA-dependent transcription, elongation || regulation of nucleotide metabolic process || positive regulation of cellular protein metabolic process || regulation of purine nucleotide metabolic process || negative regulation of proteolysis || regulation of proteasomal protein catabolic process || regulation of phosphorus metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || positive regulation of phosphorus metabolic process || regulation of protein ubiquitination || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || regulation of cellular protein metabolic process || negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || regulation of phosphate metabolic process || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of cellular catabolic process || regulation of nucleoside metabolic process || positive regulation of GTPase activity || positive regulation of MAP kinase activity || regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
positive regulation of cellular process |
1 |
0.9066 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of phosphorus metabolic process || positive regulation of cell cycle arrest || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of stress-activated MAPK cascade || positive regulation of transforming growth factor beta receptor signaling pathway || positive regulation of cell communication || positive regulation of cellular protein metabolic process || positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of metabolic process |
0.9145 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of phosphorus metabolic process || positive regulation of protein metabolic process || positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc || positive regulation of cellular protein metabolic process || positive regulation of MAP kinase activity |
| Biological Process (BP) |
negative regulation of metabolic process |
0.6689 |
1.222 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of DNA-dependent transcription, elongation || negative regulation of catabolic process || negative regulation of protein catabolic process || negative regulation of protein metabolic process || negative regulation of proteolysis |
| Biological Process (BP) |
monocarboxylic acid metabolic process |
1 |
1.155 |
Moderately Informative |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
small molecule biosynthetic process |
1 |
1 |
Moderately Informative |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
ion transport |
1 |
1.194 |
Moderately Informative |
INHERITED FROM: dopamine transport || dopamine uptake involved in synaptic transmission || dopamine uptake |
| Biological Process (BP) |
organic substance transport |
1 |
0.9747 |
Moderately Informative |
INHERITED FROM: dopamine transport || dopamine uptake involved in synaptic transmission || catecholamine uptake involved in synaptic transmission || dopamine uptake || monoamine transport || catecholamine uptake || catecholamine transport |
| Biological Process (BP) |
regulation of multicellular organismal process |
0.9687 |
0.9666 |
Moderately Informative |
INHERITED FROM: dorsal closure, elongation of leading edge cells || positive regulation of type I interferon production || negative regulation of type I interferon production || negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || regulation of embryonic development || regulation of establishment of planar polarity || negative regulation of nervous system development || regulation of synaptic transmission || regulation of skeletal muscle fiber development || regulation of type I interferon production || regulation of synapse assembly || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
anatomical structure morphogenesis |
0.0167 |
1.036 |
Moderately Informative |
INHERITED FROM: establishment of tissue polarity || dorsal closure, elongation of leading edge cells || axial mesoderm formation || cell morphogenesis || convergent extension || axon extension || ommatidial rotation || embryonic morphogenesis || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || post-anal tail morphogenesis || formation of primary germ layer || germ-band shortening || axial mesoderm morphogenesis || tissue morphogenesis || lamellipodium morphogenesis || chaeta morphogenesis || neural plate morphogenesis || establishment of planar polarity |
| Biological Process (BP) |
reproduction |
0.6032 |
1.097 |
Moderately Informative |
INHERITED FROM: synaptonemal complex assembly || synapsis || chromosome organization involved in meiosis |
| Biological Process (BP) |
cellular component biogenesis |
0.0484 |
0.983 |
Moderately Informative |
INHERITED FROM: synaptonemal complex assembly || autophagic vacuole assembly || tubulin complex biogenesis || protein polymerization || microvillus assembly || post-chaperonin tubulin folding pathway |
| Biological Process (BP) |
phosphate-containing compound metabolic process |
0.05725 |
0.8182 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || phosphatidylinositol phosphorylation || pathway-restricted SMAD protein phosphorylation || phosphorylation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || peptidyl-tyrosine dephosphorylation || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation |
| Biological Process (BP) |
organophosphate metabolic process |
0.9682 |
0.9914 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || phosphatidylinositol phosphorylation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || phospholipid biosynthetic process || phosphatidylinositol metabolic process |
| Biological Process (BP) |
cellular lipid metabolic process |
0.3846 |
0.9747 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || phosphatidylinositol phosphorylation || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid metabolic process || glycerolipid metabolic process || glycerophospholipid metabolic process || glycerophospholipid biosynthetic process || glycerolipid biosynthetic process || phospholipid biosynthetic process || phosphatidylinositol metabolic process || lipid phosphorylation || lipid modification |
| Biological Process (BP) |
lipid biosynthetic process |
0.02332 |
1.18 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol biosynthetic process || glycerophospholipid biosynthetic process || glycerolipid biosynthetic process || fatty acid elongation || phosphatidylinositol-3-phosphate biosynthetic process || phospholipid biosynthetic process |
| Biological Process (BP) |
organic hydroxy compound metabolic process |
1 |
1.208 |
Moderately Informative |
INHERITED FROM: catecholamine metabolic process || catechol-containing compound metabolic process || dopamine metabolic process || norepinephrine metabolic process |
| Biological Process (BP) |
homeostatic process |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: lymphocyte homeostasis || leukocyte homeostasis || B cell homeostasis || ubiquitin homeostasis |
| Biological Process (BP) |
tissue development |
0.5489 |
1.143 |
Moderately Informative |
INHERITED FROM: neural plate development || dorsal closure, elongation of leading edge cells || axial mesoderm formation || convergent extension || axial mesoderm development || ommatidial rotation || epidermis morphogenesis || initiation of dorsal closure || axial mesoderm morphogenesis || tissue morphogenesis || ectoderm development || neural plate morphogenesis || establishment of planar polarity |
| Biological Process (BP) |
single-organism developmental process |
0.8193 |
0.7645 |
Moderately Informative |
INHERITED FROM: neural plate development || establishment of tissue polarity || dorsal closure, elongation of leading edge cells || embryo development || axon extension || embryonic morphogenesis || epidermis morphogenesis || initiation of dorsal closure || cochlea morphogenesis || post-anal tail morphogenesis || formation of primary germ layer || embryonic development via the syncytial blastoderm || tissue morphogenesis || neural plate morphogenesis || establishment of planar polarity || axial mesoderm formation || cell morphogenesis || convergent extension || ommatidial rotation || germ-band shortening || axial mesoderm morphogenesis || collagen and cuticulin-based cuticle development || lamellipodium morphogenesis || chaeta morphogenesis || cochlea development |
| Biological Process (BP) |
proteolysis |
1.348e-09 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
phospholipid metabolic process |
1.824e-06 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cytoskeleton organization |
1.881e-08 |
1.301 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphorus metabolic process |
1.38e-07 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
0.000182 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell communication |
0.0007357 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular membrane organization |
2.682e-06 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1.251e-07 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signaling |
0.0001874 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
actin filament-based process |
5.015e-10 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
protein catabolic process |
0 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular catabolic process |
0 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule catabolic process |
0 |
1.398 |
Informative |
DIRECT |
| Biological Process (BP) |
glycerolipid metabolic process |
1.658e-09 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.0007416 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic morphogenesis |
4.199e-05 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
tissue morphogenesis |
0.0005123 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein metabolic process |
2.333e-06 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of protein metabolic process |
5.73e-06 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
protein modification by small protein conjugation or removal |
0 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic organ development |
0.7257 |
1.699 |
Informative |
INHERITED FROM: cochlea morphogenesis |
| Biological Process (BP) |
cell projection organization |
0.05246 |
1.553 |
Informative |
INHERITED FROM: lamellipodium morphogenesis || axon extension || microvillus assembly || microvillus organization |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.5018 |
1.377 |
Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
regulation of cell cycle process |
0.7293 |
1.553 |
Informative |
INHERITED FROM: positive regulation of cell cycle arrest || regulation of cell cycle arrest |
| Biological Process (BP) |
chromosome organization |
1 |
1.62 |
Informative |
INHERITED FROM: chromosome organization involved in meiosis || synaptonemal complex assembly || synapsis || synaptonemal complex organization |
| Biological Process (BP) |
cell cycle process |
0.9808 |
1.377 |
Informative |
INHERITED FROM: chromosome organization involved in meiosis || synaptonemal complex assembly || synapsis |
| Biological Process (BP) |
cellular process involved in reproduction |
0.7138 |
1.495 |
Informative |
INHERITED FROM: chromosome organization involved in meiosis || synaptonemal complex assembly || synapsis |
| Biological Process (BP) |
protein phosphorylation |
1 |
1.585 |
Informative |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
0.2603 |
1.658 |
Informative |
INHERITED FROM: pathway-restricted SMAD protein phosphorylation |
| Biological Process (BP) |
negative regulation of developmental process |
0.9208 |
1.699 |
Informative |
INHERITED FROM: negative regulation of synapse assembly || negative regulation of nervous system development || negative regulation of developmental growth |
| Biological Process (BP) |
regulation of nervous system development |
0.02841 |
1.658 |
Informative |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || regulation of synapse assembly || negative regulation of nervous system development || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
regulation of cellular component biogenesis |
0.0622 |
1.658 |
Informative |
INHERITED FROM: negative regulation of synapse assembly || regulation of synaptic growth at neuromuscular junction || regulation of synapse assembly |
| Biological Process (BP) |
negative regulation of cellular component organization |
1 |
1.62 |
Informative |
INHERITED FROM: negative regulation of synapse assembly |
| Biological Process (BP) |
synaptic transmission |
0.1859 |
1.523 |
Informative |
INHERITED FROM: regulation of synapse assembly || negative regulation of synapse assembly || synaptic transmission, dopaminergic || synaptic transmission, glutamatergic || catecholamine uptake involved in synaptic transmission || regulation of synaptic growth at neuromuscular junction || neurotransmitter uptake || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
nitrogen compound transport |
1 |
1.377 |
Informative |
INHERITED FROM: catecholamine uptake involved in synaptic transmission || dopamine transport || dopamine uptake involved in synaptic transmission || dopamine uptake || monoamine transport || catecholamine uptake || catecholamine transport |
| Biological Process (BP) |
cellular macromolecular complex assembly |
0.3834 |
1.523 |
Informative |
INHERITED FROM: protein polymerization |
| Biological Process (BP) |
regulation of system process |
0.7236 |
1.553 |
Informative |
INHERITED FROM: regulation of synaptic transmission |
| Biological Process (BP) |
growth |
0.8167 |
1.523 |
Informative |
INHERITED FROM: axon extension || dorsal closure, elongation of leading edge cells |
| Biological Process (BP) |
generation of neurons |
0.6529 |
1.469 |
Informative |
INHERITED FROM: axon extension |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
0.04681 |
1.444 |
Informative |
INHERITED FROM: axial mesoderm formation || formation of primary germ layer |
| Biological Process (BP) |
cellular component movement |
0.1929 |
1.398 |
Informative |
INHERITED FROM: macrophage chemotaxis || leukocyte migration |
| Biological Process (BP) |
locomotion |
0.09461 |
1.444 |
Informative |
INHERITED FROM: macrophage chemotaxis || leukocyte migration |
| Biological Process (BP) |
localization of cell |
0.1191 |
1.585 |
Informative |
INHERITED FROM: macrophage chemotaxis || leukocyte migration |
| Biological Process (BP) |
response to external stimulus |
0.1284 |
1.319 |
Informative |
INHERITED FROM: macrophage chemotaxis || macroautophagy || startle response || autophagic vacuole assembly |
| Biological Process (BP) |
regulation of anatomical structure size |
1 |
1.745 |
Informative |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
protein localization to organelle |
0.07164 |
1.523 |
Informative |
INHERITED FROM: protein insertion into ER membrane |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.07961 |
1.337 |
Informative |
INHERITED FROM: positive regulation of GTPase activity || positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of protein phosphorylation |
1 |
1.495 |
Informative |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of kinase activity |
0.09422 |
1.62 |
Informative |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
regulation of hydrolase activity |
0.9804 |
1.42 |
Informative |
INHERITED FROM: regulation of GTPase activity || positive regulation of GTPase activity |
| Biological Process (BP) |
apoptotic process |
0.7121 |
1.553 |
Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway in response to DNA damage || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
response to DNA damage stimulus |
0.9059 |
1.495 |
Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process (BP) |
cell activation |
0.03279 |
1.495 |
Informative |
INHERITED FROM: B cell activation |
| Biological Process (BP) |
regulation of intracellular transport |
0.007482 |
1.585 |
Informative |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of protein localization |
0.2353 |
1.585 |
Informative |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
dephosphorylation |
0.4894 |
1.699 |
Informative |
INHERITED FROM: peptidyl-tyrosine dephosphorylation |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
1 |
1.745 |
Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription elongation from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
negative regulation of biosynthetic process |
0.9749 |
1.62 |
Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
1 |
1.745 |
Informative |
INHERITED FROM: negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of DNA-dependent transcription, elongation |
| Biological Process (BP) |
regulation of immune response |
1 |
1.553 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 5 signaling pathway || T cell receptor signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of immune system process |
0.8885 |
1.62 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor 5 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || T cell receptor signaling pathway |
| Biological Process (BP) |
regulation of response to stress |
0.8089 |
1.42 |
Informative |
INHERITED FROM: positive regulation of stress-activated MAPK cascade || toll-like receptor 2 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || toll-like receptor 5 signaling pathway || regulation of stress-activated protein kinase signaling cascade || toll-like receptor 4 signaling pathway || TRIF-dependent toll-like receptor signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway || regulation of JNK cascade || MyD88-dependent toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of signal transduction |
0.01986 |
1.377 |
Informative |
INHERITED FROM: positive regulation of stress-activated MAPK cascade || positive regulation of transforming growth factor beta receptor signaling pathway || positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
1 |
1.585 |
Informative |
INHERITED FROM: positive regulation of type I interferon production |
| Biological Process (BP) |
regulation of cytokine production |
1 |
1.62 |
Informative |
INHERITED FROM: negative regulation of type I interferon production || positive regulation of type I interferon production || regulation of type I interferon production |
| Biological Process (BP) |
posttranscriptional regulation of gene expression |
0.003561 |
1.745 |
Informative |
INHERITED FROM: regulation of protein stability |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.3978 |
1.301 |
Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of proteasomal protein catabolic process || negative regulation of cellular protein metabolic process || negative regulation of transcription elongation from RNA polymerase II promoter || negative regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of DNA-dependent transcription, elongation || negative regulation of proteolysis |
| Biological Process (BP) |
microtubule-based process |
0.01479 |
1.62 |
Informative |
INHERITED FROM: cytoplasmic microtubule organization |
| Biological Process (BP) |
fatty acid metabolic process |
1 |
1.42 |
Informative |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
monocarboxylic acid biosynthetic process |
1 |
1.523 |
Informative |
INHERITED FROM: fatty acid elongation |
| Biological Process (BP) |
DNA metabolic process |
1 |
1.268 |
Informative |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
intracellular signal transduction |
0.002766 |
1.398 |
Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage || stress-activated MAPK cascade || JNK cascade || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || nucleotide-binding oligomerization domain containing signaling pathway || stress-activated protein kinase signaling cascade || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cytoplasmic pattern recognition receptor signaling pathway || small GTPase mediated signal transduction || intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
regulation of cell development |
0.3034 |
1.469 |
Informative |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || regulation of skeletal muscle fiber development |
| Biological Process (BP) |
regulation of growth |
0.8927 |
1.42 |
Informative |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || negative regulation of developmental growth |
| Biological Process (BP) |
sensory organ development |
0.03897 |
1.553 |
Informative |
INHERITED FROM: chaeta morphogenesis || cochlea morphogenesis || ommatidial rotation || cochlea development |
| Biological Process (BP) |
organ morphogenesis |
0.08028 |
1.523 |
Informative |
INHERITED FROM: chaeta morphogenesis || ommatidial rotation || epidermis morphogenesis || cochlea morphogenesis |
| Biological Process (BP) |
epithelium development |
0.5206 |
1.377 |
Informative |
INHERITED FROM: neural plate development || dorsal closure, elongation of leading edge cells || convergent extension || ommatidial rotation || neural plate morphogenesis || initiation of dorsal closure || establishment of planar polarity |
| Biological Process (BP) |
chordate embryonic development |
1 |
1.495 |
Informative |
INHERITED FROM: neural plate morphogenesis || neural plate development |
| Biological Process (BP) |
cellular component morphogenesis |
0.5493 |
1.495 |
Informative |
INHERITED FROM: cell morphogenesis || lamellipodium morphogenesis || axon extension || dorsal closure, elongation of leading edge cells |
| Biological Process (BP) |
leukocyte homeostasis |
1.192e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
autophagy |
2.19e-09 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
establishment or maintenance of cell polarity |
4.008e-15 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
small GTPase mediated signal transduction |
0.000111 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of nucleoside metabolic process |
5.461e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
monoamine transport |
1.461e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
modification-dependent protein catabolic process |
0.0001982 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell morphogenesis |
2.096e-08 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of proteolysis |
2.081e-14 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lipid modification |
4.673e-05 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stress-activated protein kinase signaling cascade |
6.988e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular catabolic process |
9.398e-08 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein ubiquitination |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein stability |
6.565e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to endoplasmic reticulum stress |
7.789e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to topologically incorrect protein |
1.498e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
B cell activation |
4.154e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein catabolic process |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
glycerophospholipid biosynthetic process |
3.963e-06 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
phosphatidylinositol metabolic process |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte migration |
0.0001021 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
maintenance of location |
0.000311 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein polymerization |
0.0002786 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle arrest |
6.392e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein ubiquitination |
1 |
2.097 |
Highly Informative |
INHERITED FROM: protein linear polyubiquitination || protein autoubiquitination |
| Biological Process (BP) |
organic hydroxy compound transport |
0.01682 |
1.796 |
Highly Informative |
INHERITED FROM: dopamine uptake || catecholamine uptake || catecholamine uptake involved in synaptic transmission || catecholamine transport || dopamine transport || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
regulation of organ morphogenesis |
0.1067 |
2.222 |
Highly Informative |
INHERITED FROM: regulation of establishment of planar polarity || regulation of establishment of planar polarity involved in neural tube closure |
| Biological Process (BP) |
inner ear development |
0.2708 |
2.222 |
Highly Informative |
INHERITED FROM: cochlea morphogenesis || cochlea development |
| Biological Process (BP) |
embryonic organ morphogenesis |
0.3607 |
2 |
Highly Informative |
INHERITED FROM: cochlea morphogenesis |
| Biological Process (BP) |
cellular response to growth factor stimulus |
0.01314 |
2 |
Highly Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
positive regulation of cell cycle process |
0.4467 |
1.921 |
Highly Informative |
INHERITED FROM: positive regulation of cell cycle arrest |
| Biological Process (BP) |
meiosis |
0.06167 |
2.097 |
Highly Informative |
INHERITED FROM: chromosome organization involved in meiosis || synaptonemal complex assembly || synapsis |
| Biological Process (BP) |
response to hypoxia |
0.3529 |
1.854 |
Highly Informative |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| Biological Process (BP) |
regulation of binding |
0.01682 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of binding || positive regulation of protein binding || regulation of protein binding |
| Biological Process (BP) |
regulation of neurological system process |
0.006076 |
2 |
Highly Informative |
INHERITED FROM: regulation of synaptic transmission |
| Biological Process (BP) |
epidermis development |
0.006329 |
1.854 |
Highly Informative |
INHERITED FROM: epidermis morphogenesis |
| Biological Process (BP) |
developmental growth |
0.08894 |
1.921 |
Highly Informative |
INHERITED FROM: axon extension || dorsal closure, elongation of leading edge cells |
| Biological Process (BP) |
axonogenesis |
1 |
2 |
Highly Informative |
INHERITED FROM: axon extension |
| Biological Process (BP) |
gastrulation |
0.01022 |
2.222 |
Highly Informative |
INHERITED FROM: axial mesoderm formation || formation of primary germ layer |
| Biological Process (BP) |
chemotaxis |
0.05139 |
1.921 |
Highly Informative |
INHERITED FROM: macrophage chemotaxis |
| Biological Process (BP) |
regulation of cellular component size |
0.5904 |
1.854 |
Highly Informative |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
regulation of purine nucleotide catabolic process |
0.01644 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of GTPase activity || regulation of GTPase activity |
| Biological Process (BP) |
positive regulation of MAPK cascade |
1 |
1.854 |
Highly Informative |
INHERITED FROM: positive regulation of MAP kinase activity || positive regulation of stress-activated MAPK cascade |
| Biological Process (BP) |
regulation of MAP kinase activity |
0.09254 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
positive regulation of protein serine/threonine kinase activity |
0.2588 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of MAP kinase activity |
| Biological Process (BP) |
signal transduction by p53 class mediator |
0.001028 |
2.222 |
Highly Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
diol metabolic process |
0.001882 |
2 |
Highly Informative |
INHERITED FROM: dopamine metabolic process || norepinephrine metabolic process || catechol-containing compound metabolic process || catecholamine metabolic process |
| Biological Process (BP) |
regulation of intracellular protein transport |
0.00196 |
1.921 |
Highly Informative |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of nucleocytoplasmic transport |
0.02209 |
2 |
Highly Informative |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
regulation of protein localization to nucleus |
0.003904 |
2.097 |
Highly Informative |
INHERITED FROM: regulation of catenin import into nucleus |
| Biological Process (BP) |
protein dephosphorylation |
0.8827 |
1.854 |
Highly Informative |
INHERITED FROM: peptidyl-tyrosine dephosphorylation |
| Biological Process (BP) |
regulation of innate immune response |
0.731 |
2.097 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || TRIF-dependent toll-like receptor signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 3 signaling pathway |
| Biological Process (BP) |
activation of immune response |
0.157 |
1.921 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || TRIF-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || T cell receptor signaling pathway |
| Biological Process (BP) |
immune response-regulating signaling pathway |
0.7624 |
2 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || cytoplasmic pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || TRIF-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || nucleotide-binding oligomerization domain containing signaling pathway || T cell receptor signaling pathway |
| Biological Process (BP) |
regulation of cellular response to stress |
0.006393 |
1.921 |
Highly Informative |
INHERITED FROM: positive regulation of stress-activated MAPK cascade || regulation of JNK cascade || regulation of stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
negative regulation of RNA metabolic process |
1 |
1.921 |
Highly Informative |
INHERITED FROM: negative regulation of DNA-dependent transcription, elongation || negative regulation of transcription elongation from RNA polymerase II promoter |
| Biological Process (BP) |
positive regulation of cytokine production |
0.4087 |
1.921 |
Highly Informative |
INHERITED FROM: positive regulation of type I interferon production |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
0.2252 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of type I interferon production |
| Biological Process (BP) |
microtubule cytoskeleton organization |
0.5684 |
1.854 |
Highly Informative |
INHERITED FROM: cytoplasmic microtubule organization |
| Biological Process (BP) |
regulation of cellular response to growth factor stimulus |
0.002914 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of transforming growth factor beta receptor signaling pathway || regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
proteasomal protein catabolic process |
1 |
2.222 |
Highly Informative |
INHERITED FROM: ER-associated protein catabolic process |
| Biological Process (BP) |
negative regulation of signal transduction |
0.07606 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of Wnt receptor signaling pathway |
| Biological Process (BP) |
cell projection assembly |
0.2165 |
2 |
Highly Informative |
INHERITED FROM: microvillus assembly |
| Biological Process (BP) |
regulation of cell adhesion |
0.3044 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of cell-cell adhesion |
| Biological Process (BP) |
eye morphogenesis |
0.05293 |
1.921 |
Highly Informative |
INHERITED FROM: ommatidial rotation |
| Biological Process (BP) |
regulation of gene expression, epigenetic |
0.6805 |
2.097 |
Highly Informative |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
DNA methylation or demethylation |
0.03937 |
2.097 |
Highly Informative |
INHERITED FROM: maintenance of DNA methylation |
| Biological Process (BP) |
pattern specification process |
0.0332 |
1.921 |
Highly Informative |
INHERITED FROM: dorsal/ventral axis specification || ommatidial rotation |
| Biological Process (BP) |
phenol-containing compound metabolic process |
0.05205 |
2 |
Highly Informative |
INHERITED FROM: catechol-containing compound metabolic process || dopamine metabolic process || norepinephrine metabolic process || catecholamine metabolic process |
| Biological Process (BP) |
apoptotic signaling pathway |
0.07745 |
2 |
Highly Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage || intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
regulation of developmental growth |
0.3186 |
2.222 |
Highly Informative |
INHERITED FROM: regulation of synaptic growth at neuromuscular junction || negative regulation of developmental growth |
| Biological Process (BP) |
cell growth |
0.04641 |
2.222 |
Highly Informative |
INHERITED FROM: dorsal closure, elongation of leading edge cells || axon extension |
| Biological Process (BP) |
MAPK cascade |
0.04763 |
2 |
Highly Informative |
INHERITED FROM: JNK cascade || stress-activated MAPK cascade |
| Biological Process (BP) |
protein folding |
0.5961 |
1.796 |
Highly Informative |
INHERITED FROM: post-chaperonin tubulin folding pathway |
| Biological Process (BP) |
neuromuscular process |
0.07955 |
2.097 |
Highly Informative |
INHERITED FROM: startle response |
| Biological Process (BP) |
morphogenesis of embryonic epithelium |
0.00807 |
2 |
Highly Informative |
INHERITED FROM: neural plate morphogenesis || dorsal closure, elongation of leading edge cells || initiation of dorsal closure |
| Biological Process (BP) |
regulation of neurotransmitter levels |
0.3669 |
1.854 |
Highly Informative |
INHERITED FROM: neurotransmitter uptake || catecholamine uptake involved in synaptic transmission || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
neurotransmitter transport |
0.02861 |
2.097 |
Highly Informative |
INHERITED FROM: neurotransmitter uptake || catecholamine uptake involved in synaptic transmission || dopamine uptake involved in synaptic transmission |
| Biological Process (BP) |
cellular response to starvation |
0.3421 |
1.921 |
Highly Informative |
INHERITED FROM: autophagic vacuole assembly || macroautophagy |
| Biological Process (BP) |
organelle assembly |
0.19 |
1.921 |
Highly Informative |
INHERITED FROM: autophagic vacuole assembly |
| Molecular Function (MF) |
motor activity |
5.41e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
ubiquitin thiolesterase activity |
0.0007684 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein tyrosine phosphatase activity |
1.158e-12 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
non-membrane spanning protein tyrosine phosphatase activity |
2.042e-06 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
cysteine-type peptidase activity |
1.489e-12 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
ligase activity |
0.0001381 |
1.356 |
-- |
DIRECT |
| Molecular Function (MF) |
Ras GTPase binding |
1.504e-11 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
SUMO ligase activity |
3.576e-06 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein domain specific binding |
6.167e-08 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding, bridging |
3.103e-07 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
actin-dependent ATPase activity |
3.491e-07 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
small GTPase binding |
3.557e-11 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein tag |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
small conjugating protein binding |
0 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleoprotein complex binding |
0.0004611 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
ribosome binding |
2.89e-07 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
ubiquitin binding |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
small conjugating protein ligase binding |
3.934e-07 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
binding, bridging |
3.575e-08 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
nucleoside-triphosphatase regulator activity |
0 |
1.724 |
-- |
DIRECT |
| Molecular Function (MF) |
catalytic activity |
1 |
0.2686 |
-- |
INHERITED FROM: phosphatidylinositol bisphosphate kinase activity || phosphatidylinositol 3-kinase activity || SUMO ligase activity || 2'-5'-oligoadenylate synthetase activity || small conjugating protein-specific protease activity || ligase activity || cysteine-type peptidase activity || non-membrane spanning protein tyrosine kinase activity || ubiquitin thiolesterase activity || actin-dependent ATPase activity || phosphatidylinositol kinase activity || phosphoprotein phosphatase activity || non-membrane spanning protein tyrosine phosphatase activity || phosphatidylinositol phosphate kinase activity || transferase activity, transferring phosphorus-containing groups || small conjugating protein ligase activity || ligase activity, forming carbon-nitrogen bonds || motor activity || diacylglycerol kinase activity || protein tyrosine phosphatase activity |
| Molecular Function (MF) |
nucleic acid binding |
1 |
1.11 |
-- |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
double-stranded DNA binding |
0.00505 |
2.679 |
-- |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
molecular_function |
0.0393 |
0 |
-- |
INHERITED FROM: small GTPase binding || phosphatidylinositol bisphosphate kinase activity || phosphatidylinositol 3-kinase activity || SUMO ligase activity || 2'-5'-oligoadenylate synthetase activity || protein tag || small conjugating protein ligase binding || ribosome binding || ligase activity || cysteine-type peptidase activity || non-membrane spanning protein tyrosine kinase activity || binding, bridging || ubiquitin thiolesterase activity || actin-dependent ATPase activity || phosphatidylinositol kinase activity || cytoskeletal protein binding || enzyme binding || proteasome binding || enzyme regulator activity || protein domain specific binding || transferase activity, transferring phosphorus-containing groups || ribonucleoprotein complex binding || Rap guanyl-nucleotide exchange factor activity || protein binding || ubiquitin binding || small conjugating protein binding || protein tyrosine phosphatase activity || I-SMAD binding || small conjugating protein-specific protease activity || GTPase regulator activity || phosphoprotein phosphatase activity || protein complex binding || non-membrane spanning protein tyrosine phosphatase activity || phosphatidylinositol phosphate kinase activity || Ral guanyl-nucleotide exchange factor activity || Ras GTPase binding || small conjugating protein ligase activity || ligase activity, forming carbon-nitrogen bonds || spectrin binding || PH domain binding || protein binding, bridging || hemi-methylated DNA-binding || binding || nucleoside-triphosphatase regulator activity || motor activity || beta-catenin binding || diacylglycerol kinase activity || insulin receptor substrate binding |
| Molecular Function (MF) |
ATPase activity |
1 |
1.599 |
-- |
INHERITED FROM: actin-dependent ATPase activity |
| Molecular Function (MF) |
ATPase activity, coupled |
0.9571 |
1.637 |
-- |
INHERITED FROM: actin-dependent ATPase activity |
| Molecular Function (MF) |
acid-amino acid ligase activity |
0.119 |
1.637 |
-- |
INHERITED FROM: SUMO ligase activity || small conjugating protein ligase activity |
| Molecular Function (MF) |
GTPase binding |
0.007715 |
2.679 |
-- |
INHERITED FROM: Ras GTPase binding || small GTPase binding |
| Molecular Function (MF) |
Ras guanyl-nucleotide exchange factor activity |
0.003138 |
2.377 |
-- |
INHERITED FROM: Ral guanyl-nucleotide exchange factor activity || Rap guanyl-nucleotide exchange factor activity |
| Molecular Function (MF) |
peptidase activity, acting on L-amino acid peptides |
0.1069 |
1.565 |
-- |
INHERITED FROM: cysteine-type peptidase activity || small conjugating protein-specific protease activity |
| Molecular Function (MF) |
phosphatase activity |
0.1223 |
1.565 |
-- |
INHERITED FROM: phosphoprotein phosphatase activity || protein tyrosine phosphatase activity || non-membrane spanning protein tyrosine phosphatase activity |
| Molecular Function (MF) |
protein tyrosine kinase activity |
0.003068 |
2.377 |
-- |
INHERITED FROM: non-membrane spanning protein tyrosine kinase activity |
| Molecular Function (MF) |
pyrophosphatase activity |
1 |
1.298 |
-- |
INHERITED FROM: motor activity || actin-dependent ATPase activity |
| Molecular Function (MF) |
hydrolase activity, acting on acid anhydrides |
1 |
1.281 |
-- |
INHERITED FROM: motor activity || actin-dependent ATPase activity |
| Molecular Function (MF) |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
1 |
1.281 |
-- |
INHERITED FROM: motor activity || actin-dependent ATPase activity |
| Molecular Function (MF) |
binding |
0 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
hydrolase activity |
1 |
0.6657 |
Least Informative |
INHERITED FROM: cysteine-type peptidase activity || non-membrane spanning protein tyrosine phosphatase activity || ubiquitin thiolesterase activity || actin-dependent ATPase activity || motor activity || small conjugating protein-specific protease activity || protein tyrosine phosphatase activity || phosphoprotein phosphatase activity |
| Molecular Function (MF) |
transferase activity |
0.8961 |
0.7491 |
Least Informative |
INHERITED FROM: non-membrane spanning protein tyrosine kinase activity || phosphatidylinositol bisphosphate kinase activity || phosphatidylinositol 3-kinase activity || phosphatidylinositol phosphate kinase activity || 2'-5'-oligoadenylate synthetase activity || phosphatidylinositol kinase activity || diacylglycerol kinase activity || transferase activity, transferring phosphorus-containing groups |
| Molecular Function (MF) |
protein binding |
0 |
0.77 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring phosphorus-containing groups |
1.755e-05 |
1.134 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
enzyme regulator activity |
1.21e-12 |
1.134 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
organic cyclic compound binding |
1 |
0.846 |
Moderately Informative |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
heterocyclic compound binding |
1 |
0.8932 |
Moderately Informative |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
hydrolase activity, acting on ester bonds |
0.7669 |
1.122 |
Moderately Informative |
INHERITED FROM: protein tyrosine phosphatase activity || phosphoprotein phosphatase activity || non-membrane spanning protein tyrosine phosphatase activity || ubiquitin thiolesterase activity |
| Molecular Function (MF) |
cytoskeletal protein binding |
1.789e-09 |
1.423 |
Informative |
DIRECT |
| Molecular Function (MF) |
ligase activity, forming carbon-nitrogen bonds |
1.513e-08 |
1.448 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
5.258e-07 |
1.679 |
Informative |
DIRECT |
| Molecular Function (MF) |
GTPase regulator activity |
0 |
1.724 |
Informative |
DIRECT |
| Molecular Function (MF) |
kinase activity |
0.07577 |
1.474 |
Informative |
INHERITED FROM: phosphatidylinositol kinase activity || non-membrane spanning protein tyrosine kinase activity || diacylglycerol kinase activity || phosphatidylinositol bisphosphate kinase activity || phosphatidylinositol phosphate kinase activity || phosphatidylinositol 3-kinase activity |
| Molecular Function (MF) |
phosphotransferase activity, alcohol group as acceptor |
0.01154 |
1.599 |
Informative |
INHERITED FROM: phosphatidylinositol kinase activity || non-membrane spanning protein tyrosine kinase activity || diacylglycerol kinase activity || phosphatidylinositol bisphosphate kinase activity || phosphatidylinositol phosphate kinase activity |
| Molecular Function (MF) |
DNA binding |
1 |
1.423 |
Informative |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
peptidase activity |
0.2739 |
1.502 |
Informative |
INHERITED FROM: cysteine-type peptidase activity || small conjugating protein-specific protease activity |
| Molecular Function (MF) |
phosphoric ester hydrolase activity |
0.07579 |
1.502 |
Informative |
INHERITED FROM: phosphoprotein phosphatase activity || protein tyrosine phosphatase activity || non-membrane spanning protein tyrosine phosphatase activity |
| Molecular Function (MF) |
nucleoside-triphosphatase activity |
1 |
1.502 |
Informative |
INHERITED FROM: motor activity || actin-dependent ATPase activity |
| Molecular Function (MF) |
nucleotidyltransferase activity |
0.9408 |
1.474 |
Informative |
INHERITED FROM: 2'-5'-oligoadenylate synthetase activity |
| Molecular Function (MF) |
phosphoprotein phosphatase activity |
7.383e-06 |
1.98 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
small conjugating protein ligase activity |
4.514e-10 |
1.833 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
protein complex binding |
3.529e-06 |
1.98 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
structure-specific DNA binding |
0.06837 |
2.076 |
Highly Informative |
INHERITED FROM: hemi-methylated DNA-binding |
| Molecular Function (MF) |
small GTPase regulator activity |
0.007008 |
1.9 |
Highly Informative |
INHERITED FROM: Ral guanyl-nucleotide exchange factor activity || Rap guanyl-nucleotide exchange factor activity |
| Molecular Function (MF) |
guanyl-nucleotide exchange factor activity |
0.002375 |
2.076 |
Highly Informative |
INHERITED FROM: Ral guanyl-nucleotide exchange factor activity || Rap guanyl-nucleotide exchange factor activity |
| Molecular Function (MF) |
protein kinase activity |
1 |
1.98 |
Highly Informative |
INHERITED FROM: non-membrane spanning protein tyrosine kinase activity |
| Molecular Function (MF) |
thiolester hydrolase activity |
0.02004 |
2.076 |
Highly Informative |
INHERITED FROM: ubiquitin thiolesterase activity |
| Molecular Function (MF) |
adenylyltransferase activity |
0.003009 |
2.076 |
Highly Informative |
INHERITED FROM: 2'-5'-oligoadenylate synthetase activity |
| Cellular Component (CC) |
nucleotide-excision repair complex |
0.0009837 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
7.28e-07 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
5.647e-07 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleus |
0.0007694 |
0.7857 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
0.0002184 |
0.2515 |
-- |
DIRECT |
| Cellular Component (CC) |
autophagic vacuole |
0 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
microvillus |
2.452e-09 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
extrinsic to membrane |
7.778e-05 |
1.843 |
-- |
DIRECT |
| Cellular Component (CC) |
beta-catenin destruction complex |
2.517e-10 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
non-membrane-bounded organelle |
2.659e-07 |
0.6225 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
4.584e-07 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoskeletal part |
0.0001034 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
cytosolic part |
0 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
cell cortex part |
0.0004586 |
1.696 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
5.251e-07 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
apical part of cell |
9.39e-13 |
1.763 |
-- |
DIRECT |
| Cellular Component (CC) |
anchoring junction |
4.513e-09 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
neuron projection |
1 |
1.638 |
-- |
INHERITED FROM: type Is terminal bouton || type Ib terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
axon |
1 |
2.064 |
-- |
INHERITED FROM: type Ib terminal bouton || type Is terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
axon terminus |
0.0195 |
2.542 |
-- |
INHERITED FROM: type Ib terminal bouton || type Is terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
neuron projection terminus |
0.2969 |
2.542 |
-- |
INHERITED FROM: type Ib terminal bouton || type Is terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
synapse part |
0.06239 |
1.638 |
-- |
INHERITED FROM: type Ib terminal bouton || type Is terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
extracellular region part |
1 |
1.127 |
-- |
INHERITED FROM: collagen and cuticulin-based cuticle extracellular matrix |
| Cellular Component (CC) |
organelle |
0.2468 |
0.1836 |
-- |
INHERITED FROM: non-membrane-bounded organelle || nuclear body || cytoskeleton || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || heterochromatin || U2-type spliceosomal complex || stereocilium || euchromatin || cytoskeletal part || actin cytoskeleton || stereocilium bundle || intracellular non-membrane-bounded organelle || autophagic vacuole || nucleus || actin filament |
| Cellular Component (CC) |
nuclear outer membrane-endoplasmic reticulum membrane network |
0.001626 |
1.365 |
-- |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
endoplasmic reticulum part |
0.1598 |
1.365 |
-- |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
cellular_component |
0.001368 |
0 |
-- |
INHERITED FROM: trailing edge || phosphatidylinositol 3-kinase complex || cell || cytosolic part || nuclear body || cytoskeleton || cytosol || beta-catenin destruction complex || nucleotide-excision repair complex || extrinsic to membrane || LUBAC complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || ubiquitin ligase complex || basolateral plasma membrane || cell cortex part || cytoplasm || filopodium tip || type Is terminal bouton || type Ib terminal bouton || connecting hemi-adherens junction || euchromatin || internal side of plasma membrane || apical junction complex || actin filament || cell junction || cell part || cell projection || microvillus || zonula adherens || non-membrane-bounded organelle || cell-substrate junction || filopodium || heterochromatin || lamellipodium || cell leading edge || U2-type spliceosomal complex || ruffle || collagen and cuticulin-based cuticle extracellular matrix || ER membrane insertion complex || adherens junction || stereocilium || cell projection part || cytoskeletal part || actin cytoskeleton || type I terminal bouton || anchoring junction || intracellular part || stereocilium bundle || intracellular || uropod || apical part of cell || intracellular non-membrane-bounded organelle || synapse || autophagic vacuole || cell cortex || nucleus |
| Cellular Component (CC) |
intracellular organelle |
1 |
0.1875 |
-- |
INHERITED FROM: nuclear body || cytoskeleton || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || heterochromatin || U2-type spliceosomal complex || stereocilium || euchromatin || cytoskeletal part || actin cytoskeleton || stereocilium bundle || intracellular non-membrane-bounded organelle || autophagic vacuole || nucleus || actin filament |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: nuclear body || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || U2-type spliceosomal complex || autophagic vacuole || nucleus |
| Cellular Component (CC) |
organelle part |
0.3839 |
0.3713 |
-- |
INHERITED FROM: nuclear body || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || heterochromatin || U2-type spliceosomal complex || stereocilium || euchromatin || cytoskeletal part || actin filament |
| Cellular Component (CC) |
nucleoplasm |
1 |
1.337 |
-- |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
membrane-enclosed lumen |
0.9962 |
0.9395 |
-- |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
nuclear lumen |
0.2025 |
1.161 |
-- |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
organelle lumen |
1 |
1.023 |
-- |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
plasma membrane part |
1 |
1.036 |
-- |
INHERITED FROM: basolateral plasma membrane || internal side of plasma membrane |
| Cellular Component (CC) |
membrane part |
1 |
0.6842 |
-- |
INHERITED FROM: internal side of plasma membrane || extrinsic to membrane || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || basolateral plasma membrane |
| Cellular Component (CC) |
macromolecular complex |
0.09083 |
0.4276 |
-- |
INHERITED FROM: phosphatidylinositol 3-kinase complex || beta-catenin destruction complex || nucleotide-excision repair complex || LUBAC complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || ubiquitin ligase complex || U2-type spliceosomal complex || ER membrane insertion complex || actin filament |
| Cellular Component (CC) |
cell periphery |
0.1256 |
0.8256 |
-- |
INHERITED FROM: cell cortex || basolateral plasma membrane || cell cortex part || internal side of plasma membrane |
| Cellular Component (CC) |
cell-substrate adherens junction |
0.01596 |
2.241 |
-- |
INHERITED FROM: connecting hemi-adherens junction |
| Cellular Component (CC) |
cell-cell adherens junction |
0.002361 |
2.542 |
-- |
INHERITED FROM: zonula adherens |
| Cellular Component (CC) |
chromosomal part |
0.9712 |
1.587 |
-- |
INHERITED FROM: heterochromatin || euchromatin |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1.095e-07 |
0.6225 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
0.6649 |
0.2605 |
Least Informative |
INHERITED FROM: ER membrane insertion complex || phosphatidylinositol 3-kinase complex || cytosolic part || cytosol || beta-catenin destruction complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || autophagic vacuole || cell cortex || cell cortex part |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: nuclear body || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || U2-type spliceosomal complex || autophagic vacuole || nucleus |
| Cellular Component (CC) |
intracellular organelle part |
1 |
0.3893 |
Least Informative |
INHERITED FROM: nuclear body || nucleotide-excision repair complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || heterochromatin || U2-type spliceosomal complex || euchromatin || cytoskeletal part || actin filament |
| Cellular Component (CC) |
membrane |
0.281 |
0.5731 |
Least Informative |
INHERITED FROM: internal side of plasma membrane || extrinsic to membrane || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || basolateral plasma membrane |
| Cellular Component (CC) |
protein complex |
0.03536 |
0.5639 |
Least Informative |
INHERITED FROM: phosphatidylinositol 3-kinase complex || beta-catenin destruction complex || nucleotide-excision repair complex || LUBAC complex || Cdc48p-Npl4p-Ufd1p AAA ATPase complex || ubiquitin ligase complex || ER membrane insertion complex || actin filament |
| Cellular Component (CC) |
cytosol |
0 |
0.9618 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
cytoskeleton |
1.74e-06 |
1.036 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
cell projection |
3.129e-15 |
1.079 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
extracellular region |
1 |
0.9505 |
Moderately Informative |
INHERITED FROM: collagen and cuticulin-based cuticle extracellular matrix |
| Cellular Component (CC) |
endoplasmic reticulum |
0.5769 |
1.127 |
Moderately Informative |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
endomembrane system |
0.04409 |
1.11 |
Moderately Informative |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
organelle membrane |
0.3208 |
0.8514 |
Moderately Informative |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
intracellular organelle lumen |
1 |
1.023 |
Moderately Informative |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
plasma membrane |
0.6556 |
0.9734 |
Moderately Informative |
INHERITED FROM: basolateral plasma membrane || internal side of plasma membrane |
| Cellular Component (CC) |
nuclear part |
0.6684 |
0.9505 |
Moderately Informative |
INHERITED FROM: U2-type spliceosomal complex || nucleotide-excision repair complex || nuclear body |
| Cellular Component (CC) |
ribonucleoprotein complex |
1 |
0.9505 |
Moderately Informative |
INHERITED FROM: U2-type spliceosomal complex |
| Cellular Component (CC) |
ubiquitin ligase complex |
0.0009945 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell cortex |
1.614e-15 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
actin cytoskeleton |
0.000112 |
1.428 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell junction |
0 |
1.5 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell leading edge |
0 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell projection part |
2.495e-05 |
1.337 |
Informative |
DIRECT |
| Cellular Component (CC) |
synapse |
0.0003954 |
1.462 |
Informative |
DIRECT |
| Cellular Component (CC) |
neuron part |
0.005081 |
1.542 |
Informative |
INHERITED FROM: type Is terminal bouton || type Ib terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
extracellular matrix |
1 |
1.638 |
Informative |
INHERITED FROM: collagen and cuticulin-based cuticle extracellular matrix |
| Cellular Component (CC) |
endoplasmic reticulum membrane |
0.003706 |
1.462 |
Informative |
INHERITED FROM: Cdc48p-Npl4p-Ufd1p AAA ATPase complex |
| Cellular Component (CC) |
nucleoplasm part |
1 |
1.337 |
Informative |
INHERITED FROM: nuclear body |
| Cellular Component (CC) |
vacuole |
0.06627 |
1.337 |
Informative |
INHERITED FROM: autophagic vacuole |
| Cellular Component (CC) |
chromosome |
1 |
1.462 |
Informative |
INHERITED FROM: heterochromatin || euchromatin |
| Cellular Component (CC) |
ruffle |
1.97e-09 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
actin filament |
0.0006642 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
adherens junction |
0 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
internal side of plasma membrane |
0.0004585 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
basolateral plasma membrane |
0.0004949 |
1.843 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
nuclear body |
0.00018 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
lamellipodium |
8.49e-07 |
1.763 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
cell-substrate junction |
1.221e-05 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
axon part |
0.679 |
2.064 |
Highly Informative |
INHERITED FROM: type Ib terminal bouton || type Is terminal bouton || type I terminal bouton |
| Cellular Component (CC) |
proteinaceous extracellular matrix |
0.7613 |
2.064 |
Highly Informative |
INHERITED FROM: collagen and cuticulin-based cuticle extracellular matrix |
| Cellular Component (CC) |
cell-cell junction |
1 |
1.763 |
Highly Informative |
INHERITED FROM: zonula adherens || apical junction complex |
| Cellular Component (CC) |
spliceosomal complex |
0.1131 |
2.064 |
Highly Informative |
INHERITED FROM: U2-type spliceosomal complex |
| Cellular Component (CC) |
chromatin |
0.5523 |
2.064 |
Highly Informative |
INHERITED FROM: heterochromatin || euchromatin |
0
