SUPERFAMILY 1.75 HMM library and genome assignments server


Ribosomal protein S5 domain 2-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ribosomal protein S5 domain 2-like [ 54210]
Superfamily:   Ribosomal protein S5 domain 2-like [ 54211] (12)
Families:   Translational machinery components [ 54212] (4)
  RNase P protein [ 54220]
  DNA gyrase/MutL, second domain [ 54224] (6)
  Hsp90 middle domain [ 102755]
  Ribonuclease PH domain 1-like [ 54229] (10)
  GHMP Kinase, N-terminal domain [ 54232] (6)
  Early switch protein XOL-1, N-terminal domain [ 89824]
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC [ 89827]
  Imidazole glycerol phosphate dehydratase [ 102766]
  ATP-dependent protease Lon (La), catalytic domain [ 102769]
  YigZ N-terminal domain-like [ 102772] (2)
  Formaldehyde-activating enzyme, FAE [ 117795]


Superfamily statistics
Genomes (2,490) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 58,165 171,345 102
Proteins 52,855 154,869 93


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.059991.922e-12Least InformativeInherited
Biological Process (BP)protein metabolic process0.14250.2001Least InformativeInherited
Biological Process (BP)biosynthetic process0.2458.506e-07Least InformativeInherited
Biological Process (BP)gene expression8.697e-050Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.0033481.603e-11Moderately InformativeInherited
Molecular Function (MF)structural molecule activity3.251e-050.0003913Moderately InformativeDirect
Molecular Function (MF)structural constituent of ribosome2.801e-061.518e-10InformativeDirect
Cellular Component (CC)intracellular organelle part0.1151Least InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle0.00083230.0186Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.61250.1076Least InformativeInherited
Cellular Component (CC)ribonucleoprotein complex1.468e-072.416e-13Moderately InformativeDirect
Cellular Component (CC)small ribosomal subunit1.7e-080InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular macromolecule metabolic process 1.922e-12 Least Informative Direct
Biological Process (BP) biosynthetic process 8.506e-07 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 4.008e-15 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 5.582e-11 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1.724e-05 Least Informative Direct
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.2001 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.08665 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 1.603e-11 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 7.835e-15 Moderately Informative Direct
Biological Process (BP) organelle organization 3.51e-14 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 1.213e-05 Moderately Informative Direct
Biological Process (BP) cellular response to stress 3.212e-05 Moderately Informative Direct
Biological Process (BP) cellular localization 0.8815 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.2896 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 0.9555 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.2696 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.967 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.3749 Moderately Informative Inherited
Biological Process (BP) reproduction 0.6143 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.5621 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.8972 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.2448 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) purine nucleoside metabolic process 0 Informative Direct
Biological Process (BP) organophosphate catabolic process 0 Informative Direct
Biological Process (BP) mitochondrion organization 0 Informative Direct
Biological Process (BP) ribose phosphate metabolic process 0 Informative Direct
Biological Process (BP) ribonucleoside metabolic process 0 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0 Informative Direct
Biological Process (BP) nucleoside triphosphate metabolic process 0 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 2.076e-15 Informative Direct
Biological Process (BP) cellular component disassembly 9.858e-14 Informative Direct
Biological Process (BP) purine nucleotide metabolic process 8.134e-13 Informative Direct
Biological Process (BP) isoprenoid metabolic process 1.198e-07 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 6.358e-07 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 1.823e-06 Informative Direct
Biological Process (BP) response to DNA damage stimulus 0.0003574 Informative Direct
Biological Process (BP) cell cycle process 0.0006487 Informative Direct
Biological Process (BP) protein localization to organelle 0.03347 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.469 Informative Inherited
Biological Process (BP) chromosome organization 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.05229 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.7407 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.1813 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.6747 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.9309 Informative Inherited
Biological Process (BP) ncRNA processing 0.111 Informative Inherited
Biological Process (BP) proteolysis 0.506 Informative Inherited
Biological Process (BP) protein catabolic process 0.524 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.2333 Informative Inherited
Biological Process (BP) hexose metabolic process 0.1233 Informative Inherited
Biological Process (BP) carbohydrate catabolic process 1 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.06198 Informative Inherited
Biological Process (BP) steroid metabolic process 0.09368 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.3163 Informative Inherited
Biological Process (BP) aspartate family amino acid metabolic process 0.03351 Informative Inherited
Biological Process (BP) DNA metabolic process 0.001372 Informative Inherited
Biological Process (BP) immune effector process 0.06591 Informative Inherited
Biological Process (BP) immune response 0.6052 Informative Inherited
Biological Process (BP) cell activation 0.9007 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.004207 Informative Inherited
Biological Process (BP) purine ribonucleoside catabolic process 0 Highly Informative Direct
Biological Process (BP) nucleoside triphosphate catabolic process 0 Highly Informative Direct
Biological Process (BP) nucleotide catabolic process 0 Highly Informative Direct
Biological Process (BP) purine ribonucleoside triphosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) ribonucleoprotein complex subunit organization 5.753e-12 Highly Informative Direct
Biological Process (BP) regulation of nitric oxide biosynthetic process 1.763e-11 Highly Informative Direct
Biological Process (BP) guanosine-containing compound metabolic process 7.631e-11 Highly Informative Direct
Biological Process (BP) meiosis 5.015e-10 Highly Informative Direct
Biological Process (BP) steroid biosynthetic process 2.591e-08 Highly Informative Direct
Biological Process (BP) chromosome segregation 3.378e-06 Highly Informative Direct
Biological Process (BP) response to heat 4.154e-05 Highly Informative Direct
Biological Process (BP) nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 4.495e-05 Highly Informative Direct
Biological Process (BP) sterol metabolic process 0.0001156 Highly Informative Direct
Biological Process (BP) alcohol biosynthetic process 0.0001258 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0002076 Highly Informative Direct
Biological Process (BP) RNA 3'-end processing 0.0003481 Highly Informative Direct
Biological Process (BP) nucleic acid phosphodiester bond hydrolysis 0.1283 Highly Informative Inherited
Biological Process (BP) organelle localization 0.2168 Highly Informative Inherited
Biological Process (BP) DNA recombination 0.1155 Highly Informative Inherited
Biological Process (BP) B cell activation 0.01687 Highly Informative Inherited
Biological Process (BP) leukocyte mediated immunity 0.2964 Highly Informative Inherited
Biological Process (BP) proteasomal protein catabolic process 0.6452 Highly Informative Inherited
Biological Process (BP) modification-dependent protein catabolic process 1 Highly Informative Inherited
Biological Process (BP) DNA packaging 0.004464 Highly Informative Inherited
Biological Process (BP) DNA repair 0.008659 Highly Informative Inherited
Biological Process (BP) acyl-CoA metabolic process 0.01666 Highly Informative Inherited
Biological Process (BP) polyol metabolic process 0.3532 Highly Informative Inherited
Biological Process (BP) leukocyte activation involved in immune response 0.006804 Highly Informative Inherited
Biological Process (BP) rRNA processing 0.04344 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 0.0004824 Least Informative Direct
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) structural molecule activity 0.0003913 Moderately Informative Direct
Molecular Function (MF) heterocyclic compound binding 0 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 2.094e-08 Moderately Informative Direct
Molecular Function (MF) isomerase activity 3.279e-07 Moderately Informative Direct
Molecular Function (MF) anion binding 0.002245 Moderately Informative Inherited
Molecular Function (MF) protein binding 1 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.4813 Moderately Informative Inherited
Molecular Function (MF) lyase activity 0.2729 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) structural constituent of ribosome 1.518e-10 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) nuclease activity 5.496e-11 Informative Direct
Molecular Function (MF) nucleotide binding 1.042e-08 Informative Direct
Molecular Function (MF) RNA binding 0.0004372 Informative Direct
Molecular Function (MF) DNA binding 1 Informative Inherited
Molecular Function (MF) carbon-carbon lyase activity 0.03795 Informative Inherited
Molecular Function (MF) nucleotidyltransferase activity 0.09092 Informative Inherited
Molecular Function (MF) carbon-oxygen lyase activity 0.3841 Informative Inherited
Molecular Function (MF) kinase activity 0.8006 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.6926 Informative Inherited
Molecular Function (MF) peptidase activity 1 Informative Inherited
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Molecular Function (MF) carbohydrate kinase activity 4.552e-15 Highly Informative Direct
Molecular Function (MF) ATP binding 1.143e-06 Highly Informative Direct
Molecular Function (MF) carboxy-lyase activity 5.981e-05 Highly Informative Direct
Molecular Function (MF) structure-specific DNA binding 0.0009081 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.1498 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.1076 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.0186 Least Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 2.416e-13 Moderately Informative Direct
Cellular Component (CC) cytosol 0.04201 Moderately Informative Inherited
Cellular Component (CC) mitochondrial part 0.2008 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.03887 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.00535 Moderately Informative Inherited
Cellular Component (CC) small ribosomal subunit 0 Informative Direct
Cellular Component (CC) microbody 0.0003547 Informative Direct
Cellular Component (CC) cytosolic ribosome 0.6338 Informative Inherited
Cellular Component (CC) plastid 0.004657 Informative Inherited
Cellular Component (CC) cell junction 0.6304 Informative Inherited
Cellular Component (CC) chromosome 0.01487 Informative Inherited
Cellular Component (CC) cytosolic small ribosomal subunit 0.0008972 Highly Informative Direct
Cellular Component (CC) microbody part 0.000299 Highly Informative Direct
Cellular Component (CC) mitochondrial ribosome 0.0003533 Highly Informative Direct
Cellular Component (CC) symplast 0.0005814 Highly Informative Direct
Cellular Component (CC) cell-cell junction 0.1979 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.1224 Highly Informative Inherited
Cellular Component (CC) condensed chromosome 0.007148 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.03273Least InformativeInherited
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases0Moderately InformativeDirect
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases1Moderately InformativeInherited
Enzyme Commission (EC)Sole sub-subclass for isomerases that do not belon1InformativeInherited
Enzyme Commission (EC)Aldehyde-lyases0.3584InformativeInherited
Enzyme Commission (EC)Endopeptidase La0Highly InformativeDirect
Enzyme Commission (EC)Homoserine kinase0Highly InformativeDirect
Enzyme Commission (EC)Polyribonucleotide nucleotidyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Ribonuclease P0Highly InformativeDirect
Enzyme Commission (EC)Histidinol-phosphatase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the abdomen0.01148Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.5332Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the central nervous system0.813Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the abdominal organs0.003179Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genital system0.2018Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the uterus0.0002883InformativeDirect
Phenotypic Abnormality (PA)Neoplasm by histology0.01811InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by anatomical site0.02InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the intestine0.4157InformativeInherited
Phenotypic Abnormality (PA)Uterine neoplasm1.785e-05Highly InformativeDirect
Phenotypic Abnormality (PA)Neoplasm of the large intestine4.772e-05Highly InformativeDirect
Phenotypic Abnormality (PA)Urinary tract neoplasm0.000314Highly InformativeDirect
Phenotypic Abnormality (PA)Migraine0.0003641Highly InformativeDirect
Phenotypic Abnormality (PA)Sarcoma0.0003641Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal reproductive system morphology0.09896Moderately InformativeInherited
Mammalian Phenotype (MP)decreased germ cell number0.009543InformativeInherited
Mammalian Phenotype (MP)abnormal spermatogenesis0.01982InformativeInherited
Mammalian Phenotype (MP)abnormal male meiosis0.0003686Highly InformativeDirect
Mammalian Phenotype (MP)absent gametes0.0006149Highly InformativeDirect
Mammalian Phenotype (MP)abnormal sperm number0.005949Highly InformativeInherited
Mammalian Phenotype (MP)decreased male germ cell number0.006831Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval development variant0.3432Least InformativeInherited
Worm Phenotype (WP)growth variant0.3714Least InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.01511Moderately InformativeInherited
Worm Phenotype (WP)germ cell morphology variant0.03872Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.07052Moderately InformativeInherited
Worm Phenotype (WP)germ cell compartment expansion variant0.0001344InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0001353InformativeDirect
Worm Phenotype (WP)rachis morphology variant0.0001518InformativeDirect
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0001846InformativeDirect
Worm Phenotype (WP)early larval arrest6.174e-05Highly InformativeDirect
Worm Phenotype (WP)nuclear appearance variant0.0001192Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)immune system0.02327Moderately InformativeInherited
Xenopus ANatomical entity (XAN)endocrine system0.001197InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)plant cell0.3002Least InformativeInherited
Plant ANatomical entity (PAN)guard cell1.111e-05Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.02883Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0InformativeDirect
Enzyme Commission (EC)Carboxy-lyases1InformativeInherited
Enzyme Commission (EC)Polyribonucleotide nucleotidyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Ribonuclease P0Highly InformativeDirect
Enzyme Commission (EC)DNA topoisomerase (ATP-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Aldehyde-lyases0.4301Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processDNA damage0Moderately InformativeDirect
Biological processLipid metabolism6.277e-10Moderately InformativeDirect
Biological processCarbohydrate metabolism0.0001393Moderately InformativeDirect
Biological processStress response0InformativeDirect
Biological processLipid biosynthesis0InformativeDirect
Biological processtRNA processing0InformativeDirect
Biological processSteroid metabolism0.05781InformativeInherited
Biological processElongation factor0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processIsoprene biosynthesis0Highly InformativeDirect
Biological processLipid A biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis6.302e-09Highly InformativeDirect
Biological processCholesterol biosynthesis4.809e-06Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentPeroxisome0.0002412InformativeDirect
DomainTransit peptide9.295e-06Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionRNA-binding0Moderately InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationHydrolase0.5383Least InformativeInherited
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationNuclease0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationRibonucleoprotein0Moderately InformativeDirect
Post-translational modificationProtease0.0001014Moderately InformativeDirect
Post-translational modificationIsomerase1Moderately InformativeInherited
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationEndonuclease0InformativeDirect
Post-translational modificationRibosomal protein0InformativeDirect
Post-translational modificationSerine protease0InformativeDirect
Post-translational modificationTopoisomerase0Highly InformativeDirect
Post-translational modificationS-nitrosylation2.033e-06InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)biopolymer metabolism1.122e-11Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis1.938e-13Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)alcohol metabolism1Moderately InformativeInherited
UniPathway (UP)membrane lipid metabolism1Moderately InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis0InformativeDirect
UniPathway (UP)isoprenoid biosynthesis0InformativeDirect
UniPathway (UP)histidine metabolism0InformativeDirect
UniPathway (UP)alcohol biosynthesis0.04438InformativeInherited
UniPathway (UP)terpene metabolism0.5382InformativeInherited
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)L-threonine biosynthesis0Highly InformativeDirect
UniPathway (UP)galactose metabolism0Highly InformativeDirect
UniPathway (UP)lipid IV(A) biosynthesis0Highly InformativeDirect
UniPathway (UP)protein biosynthesis1.602e-14Highly InformativeDirect
UniPathway (UP)cholesterol metabolism4.916e-06Highly InformativeDirect
UniPathway (UP)sterol biosynthesis0.001177Highly InformativeInherited

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 58 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ribosomal protein S5 domain 2-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 58 hidden Markov models representing the Ribosomal protein S5 domain 2-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]